HIV-2 genome dimerization is required for the correct processing of gag: A second-site reversion in matrix can restore both processes in dimerization-impaired mutant viruses

Journal of Virology

Volumn 86, Issue 10, 2012, Pages 5867-5876

  L'Hernault, Anne ^a   Weiss, Eva U ^a   Greatorex, Jane S ^a,b   Lever, Andrew M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; MATRIX PROTEIN; MUTANT PROTEIN; PURINE; STEM LOOP 1 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; GENETIC ANALYSIS; GENETIC PARAMETERS; GENOME DIMERIZATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PACKAGING SIGNAL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN STRUCTURE; REVERTANT; VIRAL PHENOMENA AND FUNCTIONS; VIRUS EXAMINATION; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS REPLICATION;

AMINO ACID MOTIFS; CELL LINE; DIMERIZATION; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENOME, VIRAL; HIV INFECTIONS; HIV-2; HUMANS; INVERTED REPEAT SEQUENCES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 84861312728     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00124-12     Document Type: Article

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