Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Chen, Ding Bang ^a   Feng, Li ^a   Lin, Xiao Pu ^b   Zhang, Wei ^a   Li, Fu Rong ^a   Liang, Xiu Ling ^a   Li, Xun Hua ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; COPPER; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALONALDEHYDE; MENKES PROTEIN; MESSENGER RNA; PENICILLAMINE; PROTEIN CTR1; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN LEVEL; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHOROID PLEXUS; CONTROLLED STUDY; COPPER BLOOD LEVEL; COPPER METABOLISM; GOLGI COMPLEX; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CATION TRANSPORT PROTEINS; CELL MEMBRANE; COPPER; DISEASE MODELS, ANIMAL; GLUTATHIONE SYNTHASE; GOLGI APPARATUS; HEPATOLENTICULAR DEGENERATION; MALONDIALDEHYDE; MICE; NEURONS; OXIDATIVE STRESS; PENICILLAMINE; SUPEROXIDE DISMUTASE;

ANIMALIA; MUS;

EID: 84861306264     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037709     Document Type: Article

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