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Volumn 104, Issue 10, 2012, Pages 720-722

Cotinine conundrum-A step forward but questions Remain

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYCOTININE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; COTININE; CYTOCHROME P450 2A6; NICOTINE; NICOTINIC RECEPTOR; PROTEIN CHRNA5; UNCLASSIFIED DRUG;

EID: 84861304903     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djs211     Document Type: Editorial
Times cited : (8)

References (19)
  • 1
    • 42649091460 scopus 로고    scopus 로고
    • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
    • Amos CI, Wu X, Broderick P, et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 2008;40(5):616-622.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 616-622
    • Amos, C.I.1    Wu, X.2    Broderick, P.3
  • 2
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson TE, Geller F, Sulem P, et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature. 2008;452(7187):638-642.
    • (2008) Nature , vol.452 , Issue.7187 , pp. 638-642
    • Thorgeirsson, T.E.1    Geller, F.2    Sulem, P.3
  • 3
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • Hung RJ, McKay JD, Gaborieau V, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature. 2008;452(7187):633-637.
    • (2008) Nature , vol.452 , Issue.7187 , pp. 633-637
    • Hung, R.J.1    McKay, J.D.2    Gaborieau, V.3
  • 4
    • 40849097777 scopus 로고    scopus 로고
    • Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking
    • Berrettini W, Yuan X, Tozzi F, et al. Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry. 2008;13(4):368-373.
    • (2008) Mol Psychiatry , vol.13 , Issue.4 , pp. 368-373
    • Berrettini, W.1    Yuan, X.2    Tozzi, F.3
  • 5
    • 33846510020 scopus 로고    scopus 로고
    • Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    • Saccone SF, Hinrichs AL, Saccone NL, et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet. 2007;16(1):36-49.
    • (2007) Hum Mol Genet , vol.16 , Issue.1 , pp. 36-49
    • Saccone, S.F.1    Hinrichs, A.L.2    Saccone, N.L.3
  • 6
    • 51349156208 scopus 로고    scopus 로고
    • Variants in nicotinic receptors and risk for nicotine dependence
    • Bierut LJ, Stitzel JA, Wang JC, et al. Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry. 2008;165(9):1163-1171.
    • (2008) Am J Psychiatry , vol.165 , Issue.9 , pp. 1163-1171
    • Bierut, L.J.1    Stitzel, J.A.2    Wang, J.C.3
  • 7
    • 78651336831 scopus 로고    scopus 로고
    • Acetylcholine receptor (AChR) alpha5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (alpha4beta2)alpha5 AChR function
    • Kuryatov A, Berrettini W, Lindstrom J. Acetylcholine receptor (AChR) alpha5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (alpha4beta2)alpha5 AChR function. Mol Pharmacol. 2011;79(1):119-125.
    • (2011) Mol Pharmacol , vol.79 , Issue.1 , pp. 119-125
    • Kuryatov, A.1    Berrettini, W.2    Lindstrom, J.3
  • 8
    • 84861325364 scopus 로고    scopus 로고
    • Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure
    • Munafò MR, Timofeeva MN, Morris RW, et al. Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst. 2012;104(10):740-748.
    • (2012) J Natl Cancer Inst. , vol.104 , Issue.10 , pp. 740-748
    • Munafò, M.R.1    Timofeeva, M.N.2    Morris, R.W.3
  • 9
    • 70349573295 scopus 로고    scopus 로고
    • Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15
    • Keskitalo K, Broms U, Heliövaara M, et al. Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. Hum Mol Genet. 2009;18(20):4007-4012.
    • (2009) Hum Mol Genet , vol.18 , Issue.20 , pp. 4007-4012
    • Keskitalo, K.1    Broms, U.2    Heliövaara, M.3
  • 10
    • 55749093830 scopus 로고    scopus 로고
    • The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer
    • Spitz MR, Amos CI, Dong Q, Lin J, Wu X. The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. J Natl Cancer Inst. 2008;100(21):1552-1556.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.21 , pp. 1552-1556
    • Spitz, M.R.1    Amos, C.I.2    Dong, Q.3    Lin, J.4    Wu, X.5
  • 11
    • 0037251810 scopus 로고    scopus 로고
    • Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
    • West KA, Brognard J, Clark AS, et al. Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. J Clin Invest. 2003;111(1):81-90.
    • (2003) J Clin Invest , vol.111 , Issue.1 , pp. 81-90
    • West, K.A.1    Brognard, J.2    Clark, A.S.3
  • 12
    • 34250307900 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers
    • Lam DC, Girard L, Ramirez R, et al. Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers. Cancer Res. 2007;67(10):4638-4647.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4638-4647
    • Lam, D.C.1    Girard, L.2    Ramirez, R.3
  • 13
    • 84859261460 scopus 로고    scopus 로고
    • Dissection of the phenotypic and genotypic associations with nicotinic dependence
    • Chen LS, Baker TB, Grucza R, et al. Dissection of the phenotypic and genotypic associations with nicotinic dependence. Nicotine Tob Res. 2012;14(4):425-433.
    • (2012) Nicotine Tob Res. , vol.14 , Issue.4 , pp. 425-433
    • Chen, L.S.1    Baker, T.B.2    Grucza, R.3
  • 14
    • 56449101208 scopus 로고    scopus 로고
    • Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine
    • Le Marchand L, Derby KS, Murphy SE, et al. Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine. Cancer Res. 2008;68(22):9137-9140.
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9137-9140
    • Le Marchand, L.1    Derby, K.S.2    Murphy, S.E.3
  • 15
    • 58449110294 scopus 로고    scopus 로고
    • A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers
    • Church TR, Anderson KE, Caporaso NE, et al. A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer Epidemiol Biomarkers Prev. 2009;18(1):260-266.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.1 , pp. 260-266
    • Church, T.R.1    Anderson, K.E.2    Caporaso, N.E.3
  • 16
    • 80052681515 scopus 로고    scopus 로고
    • Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk
    • Wassenaar CA, Dong Q, Wei Q, Amos CI, Spitz MR, Tyndale RF. Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. J Natl Cancer Inst. 2011;103(17):1342-1346.
    • (2011) J Natl Cancer Inst , vol.103 , Issue.17 , pp. 1342-1346
    • Wassenaar, C.A.1    Dong, Q.2    Wei, Q.3    Amos, C.I.4    Spitz, M.R.5    Tyndale, R.F.6
  • 17
    • 80052027888 scopus 로고    scopus 로고
    • Recent advances in gene manipulation and nicotinic acetylcholine receptor biology
    • Tammimäki A, Horton WJ, Stitzel JA. Recent advances in gene manipulation and nicotinic acetylcholine receptor biology. Biochem Pharmacol. 2011;82(8):808-819.
    • (2011) Biochem Pharmacol , vol.82 , Issue.8 , pp. 808-819
    • Tammimäki, A.1    Horton, W.J.2    Stitzel, J.A.3
  • 18
    • 79959877467 scopus 로고    scopus 로고
    • Reward, addiction, withdrawal to nicotine
    • De Biasi M, Dani JA. Reward, addiction, withdrawal to nicotine. Annu Rev Neurosci. 2011;34:105-130.
    • (2011) Annu Rev Neurosci , vol.34 , pp. 105-130
    • De Biasi, M.1    Dani, J.A.2
  • 19
    • 70350215708 scopus 로고    scopus 로고
    • Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1
    • Liu Y, Liu P, Wen W, et al. Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Res. 2009;69(19):7844-7850.
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7844-7850
    • Liu, Y.1    Liu, P.2    Wen, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.