2-Amino-3-cyano-4-(5-arylisoxazol-3-yl)-4H-chromenes: Synthesis and in vitro cytotoxic activity

Archiv der Pharmazie

Volumn 345, Issue 5, 2012, Pages 386-392

  Akbarzadeh, Tahmineh ^a   Rafinejad, Ali ^a   Mollaghasem, Javad Malekian ^a   Safavi, Maliheh ^a   Fallah Tafti, Asal ^a   Pordeli, Mahboobeh ^b   Ardestani, Sussan Kabudanian ^b   Shafiee, Abbas ^a   Foroumadi, Alireza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

Author keywords

4 (5 Arylisoxazol 3 yl) 4H chromenes; Cancer; Cytotoxic activity; Synthesis

Indexed keywords

2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 (5 PHENYLISOXAZOL 3 YL) 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (2 FLUOROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (2,4 DICHLOROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (3 METHOXYPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (3 METHYLPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (3 NITROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (3,4 DIMETHOXYPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (3,4,5 TRIMETHOXYPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (4 BROMOPHENYL) ISOXAZOL 3 YL) 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (4 FLUOROPHENYL)ISOXAZOL 3 YL)4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (4 METHOXYPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (4 METHYLPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5 (4 NITROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5(2 CHLOROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 2 AMINO 3 CYANO 7 DIMETHYLAMINO 4 [5(4 CHLOROPHENYL)ISOXAZOL 3 YL] 4H CHROMENE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYTOTOXIC AGENT; DOXORUBICIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CELL STRAIN HEPG2; CELL STRAIN KB; CELL STRAIN MCF 7; COLORIMETRY; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CARCINOMA; NASOPHARYNX CARCINOMA; NEUROBLASTOMA; PRIORITY JOURNAL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BENZOPYRANS; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS;

EID: 84861302776     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100345     Document Type: Article

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