-
1
-
-
0033828949
-
Genetic polymorphism of thiopurine S-methyltransferase: Molecular mechanisms and clinical importance
-
Krynetski EY, Evans WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology. 2000;61:136-146.
-
(2000)
Pharmacology
, vol.61
, pp. 136-146
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
2
-
-
34250304874
-
Clinical pharmacogenomics of thiopurine S-methyltransferase
-
Zhou S. Clinical pharmacogenomics of thiopurine S-methyltransferase. Curr Clin Pharmacol. 2006;1:119-128.
-
(2006)
Curr Clin Pharmacol
, vol.1
, pp. 119-128
-
-
Zhou, S.1
-
3
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet. 1980;32:651-662. (Pubitemid 10061685)
-
(1980)
American Journal of Human Genetics
, vol.32
, Issue.5
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
4
-
-
0027524983
-
Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia
-
Lennard L, Gibson BES, Nicole T, et al. Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia. Arch Dis Child. 1993;69:577-579. (Pubitemid 23355853)
-
(1993)
Archives of Disease in Childhood
, vol.69
, Issue.5
, pp. 577-579
-
-
Lennard, L.1
Gibson, B.E.S.2
Nicole, T.3
Lilleyman, J.S.4
-
5
-
-
67349087340
-
TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients
-
Kurzawski M, Dziewanowski K, Lener A, et al. TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients. Eur J Clin Pharmacol. 2009;65:533-540.
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 533-540
-
-
Kurzawski, M.1
Dziewanowski, K.2
Lener, A.3
-
6
-
-
38549151340
-
Characterization of the inosine triphosphatase (ITPA) gene: Haplotype structure, haplotype-phenotype correlation and promoter function
-
DOI 10.1097/FTD.0b013e318161a21a, PII 0000769120080200000004
-
Von Ahsen N, Oellerich M, Armstrong VW. Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotypephenotype correlation and promoter function. Ther Drug Monit. 2008; 30:16-22. (Pubitemid 351161094)
-
(2008)
Therapeutic Drug Monitoring
, vol.30
, Issue.1
, pp. 16-22
-
-
Von Ahsen, N.1
Oellerich, M.2
Armstrong, V.W.3
-
7
-
-
34547830873
-
Meta-analysis: Inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease
-
DOI 10.1111/j.1365-2036.2007.03412.x
-
Van Dieren JM, Hansen BE, Kuipers EJ, et al. Meta-analysis: inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease. Aliment Pharmacol Ther. 2007;26:643-652. (Pubitemid 47246201)
-
(2007)
Alimentary Pharmacology and Therapeutics
, vol.26
, Issue.5
, pp. 643-652
-
-
Van Dieren, J.M.1
Hansen, B.E.2
Kuipers, E.J.3
Nieuwenhuis, E.E.S.4
Van Der Woude, C.J.5
-
8
-
-
67651163895
-
Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease
-
Smith MA, Marinaki AM, Arenas M, et al. Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease. Aliment Pharmacol Ther. 2009;30:375-384.
-
(2009)
Aliment Pharmacol Ther
, vol.30
, pp. 375-384
-
-
Smith, M.A.1
Marinaki, A.M.2
Arenas, M.3
-
9
-
-
0029900435
-
Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH)
-
DOI 10.1006/geno.1996.0262
-
Xu P, Huecksteadt TP, Hoidal JR. Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH). Genomics. 1996; 34:173-180. (Pubitemid 26172841)
-
(1996)
Genomics
, vol.34
, Issue.2
, pp. 173-180
-
-
Xu, P.1
Huecksteadt, T.P.2
Hoidal, J.R.3
-
10
-
-
0021028642
-
Inhibition of first-pass metabolism in cancer chemotherapy: Interaction of 6-mercaptopurine and allopurinol
-
Zimm S, Collins JM, O'Neill D, et al. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol. Clin Pharmacol Ther. 1983;34:810-817. (Pubitemid 14219930)
-
(1983)
Clinical Pharmacology and Therapeutics
, vol.34
, Issue.6
, pp. 810-817
-
-
Zimm, S.1
Collins, J.M.2
O'Neill, D.3
-
11
-
-
0029987936
-
Detection and identification of 6-methylmercapto-8-hydroxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration
-
Keuzenkamp-Jansen CW, van Baal JM, De Abreu RA, et al. Detection and identification of 6-methylmercapto-8-hydoxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration. Clin Chem. 1996;42:380-386. (Pubitemid 26080922)
-
(1996)
Clinical Chemistry
, vol.42
, Issue.3
, pp. 380-386
-
-
Keuzenkamp-Jansen, C.W.1
Van Baal, J.M.2
De Abreu, R.A.3
De Jong, J.G.N.4
Zuiderent, R.5
Trijbels, J.M.F.6
-
12
-
-
0034812332
-
Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II
-
DOI 10.1006/bbrc.2001.4719
-
Ichida K, Matsumura T, Sakuma R, et al. Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II. Biochem Biophys Res Commun. 2001;282:1194-1200. (Pubitemid 32912852)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.282
, Issue.5
, pp. 1194-1200
-
-
Ichida, K.1
Matsumura, T.2
Sakuma, R.3
Hosoya, T.4
Nishino, T.5
-
13
-
-
42049122605
-
Role of pharmacogenetics of immunosuppressive drugs in organ transplantation
-
DOI 10.1097/FTD.0b013e31816babef, PII 0000769120080400000003
-
Thervet E, Anglicheau D, Legendre C, et al. Role of pharmacogenetics of immunosuppressive drugs in organ transplantation. Ther Drug Monit. 2008;30:143-150. (Pubitemid 351521640)
-
(2008)
Therapeutic Drug Monitoring
, vol.30
, Issue.2
, pp. 143-150
-
-
Thervet, E.1
Anglicheau, D.2
Legendre, C.3
Beaune, P.4
-
14
-
-
45849107951
-
Clinical pharmacology and pharmacogenetics of thiopurines
-
Sahasranaman S, Howard D, Roy S. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008;64: 753-767.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 753-767
-
-
Sahasranaman, S.1
Howard, D.2
Roy, S.3
-
15
-
-
12144285961
-
Adverse drug reactions to azathioptine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
-
DOI 10.1097/00008571-200403000-00006
-
Marinaki AM, Ansari A, Duley JA, et al. Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Pharmacogenetics. 2004;14:181-187. (Pubitemid 38373112)
-
(2004)
Pharmacogenetics
, vol.14
, Issue.3
, pp. 181-187
-
-
Marinaki, A.M.1
Ansari, A.2
Duley, J.A.3
Arenas, M.4
Sumi, S.5
Lewis, C.M.6
Shobowale-Bakre, E.-M.7
Escuredo, E.8
Fairbanks, L.D.9
Sanderson, J.D.10
-
16
-
-
33645885609
-
Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease
-
Stocco G, Martelossi S, Sartor F, et al. Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease. Dig Dis Sci. 2006;51:474-479.
-
(2006)
Dig Dis Sci
, vol.51
, pp. 474-479
-
-
Stocco, G.1
Martelossi, S.2
Sartor, F.3
-
17
-
-
78249243846
-
The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease
-
Ban H, Andoh A, Imaeda H, et al. The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease. J Gastroenterol. 2010;45:1014-1021.
-
(2010)
J Gastroenterol
, vol.45
, pp. 1014-1021
-
-
Ban, H.1
Andoh, A.2
Imaeda, H.3
-
18
-
-
79955904447
-
Evidence for a functional genetic polymorphism of the Rho-GTPase Rac1.Implication in azathioprine response?
-
Bourgine J, Garat A, Allorge D, et al. Evidence for a functional genetic polymorphism of the Rho-GTPase Rac1. Implication in azathioprine response? Pharmacogenet Genomics. 2011;21:313-324.
-
(2011)
Pharmacogenet Genomics
, vol.21
, pp. 313-324
-
-
Bourgine, J.1
Garat, A.2
Allorge, D.3
-
19
-
-
80051788056
-
Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease
-
Shipkova M, Franz J, Abe M, et al. Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease. Ther Drug Monit. 2011;33:321-328.
-
(2011)
Ther Drug Monit
, vol.33
, pp. 321-328
-
-
Shipkova, M.1
Franz, J.2
Abe, M.3
-
20
-
-
34848819742
-
In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase
-
Rashidi MR, Beedham C, Smith JS, et al. In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase. Drug Metab Pharmacokinet. 2007;22:299-306.
-
(2007)
Drug Metab Pharmacokinet
, vol.22
, pp. 299-306
-
-
Rashidi, M.R.1
Beedham, C.2
Smith, J.S.3
-
22
-
-
77956961565
-
Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase
-
Kudo M, Sasaki T, Ishikawa M, et al. Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase. Drug Metab Pharmacokinet. 2010;25:361-366.
-
(2010)
Drug Metab Pharmacokinet
, vol.25
, pp. 361-366
-
-
Kudo, M.1
Sasaki, T.2
Ishikawa, M.3
-
23
-
-
78951470115
-
Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene
-
Kudo M, Sasaki T, Ishikawa M, et al. Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene. Drug Metab Pharmacokinet. 2010;25:599-604.
-
(2010)
Drug Metab Pharmacokinet
, vol.25
, pp. 599-604
-
-
Kudo, M.1
Sasaki, T.2
Ishikawa, M.3
-
24
-
-
0022504824
-
The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver
-
Ikegami T, Nishino T. The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver. Arch Biochem Biophys. 1986;247:254-260. (Pubitemid 16077528)
-
(1986)
Archives of Biochemistry and Biophysics
, vol.247
, Issue.2
, pp. 254-260
-
-
Ikegami, T.1
Nishino, T.2
-
25
-
-
0345375261
-
Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II
-
DOI 10.1016/S0026-0495(03)00272-5
-
Yamamoto T, Moriwaki Y, Takahashi S, et al. Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II. Metabolism. 2003;52:1501-1504. (Pubitemid 37461122)
-
(2003)
Metabolism: Clinical and Experimental
, vol.52
, Issue.11
, pp. 1501-1504
-
-
Yamamoto, T.1
Moriwaki, Y.2
Takahashi, S.3
Tsutsumi, Z.4
Tuneyoshi, K.5
Matsui, K.6
Cheng, J.7
Hada, T.8
-
26
-
-
73649092728
-
Human Genetic variation, Population Pharmacokinetic-dynamic models, Bayesian feedback control, and maximally precise Individualized drug dosage regimens
-
Jelliffe R, Schumitzky A, Bayard D, et al. Human Genetic variation, Population Pharmacokinetic-dynamic models, Bayesian feedback control, and maximally precise Individualized drug dosage regimens. Curr Pharmacogenomics Person Med. 2009;7:249-262.
-
(2009)
Curr Pharmacogenomics Person Med
, vol.7
, pp. 249-262
-
-
Jelliffe, R.1
Schumitzky, A.2
Bayard, D.3
|