메뉴 건너뛰기




Volumn 34, Issue 3, 2012, Pages 266-274

Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine

Author keywords

Aldehyde oxidase1 (AOX1); Azathioprine (AZA); Genetic polymorphism; Kidney transplantation; Molybdenum cofactor sulfurase (MOCOS); Xanthine dehydrogenase (XDH)

Indexed keywords

ACETYLSALICYLIC ACID; ALANINE AMINOTRANSFERASE; ALDEHYDE OXIDASE; ALDEHYDE OXIDASE 1; AZATHIOPRINE; BASILIXIMAB; CEFUROXIME; COTRIMOXAZOLE; CYCLOSPORIN; CYCLOSPORIN A; ENZYME; MOLYBDENUM COFACTOR SULFURASE; PREDNISONE; PURINE; UNCLASSIFIED DRUG; XANTHINE DEHYDROGENASE;

EID: 84861232022     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e31824aa681     Document Type: Article
Times cited : (32)

References (26)
  • 1
    • 0033828949 scopus 로고    scopus 로고
    • Genetic polymorphism of thiopurine S-methyltransferase: Molecular mechanisms and clinical importance
    • Krynetski EY, Evans WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology. 2000;61:136-146.
    • (2000) Pharmacology , vol.61 , pp. 136-146
    • Krynetski, E.Y.1    Evans, W.E.2
  • 2
    • 34250304874 scopus 로고    scopus 로고
    • Clinical pharmacogenomics of thiopurine S-methyltransferase
    • Zhou S. Clinical pharmacogenomics of thiopurine S-methyltransferase. Curr Clin Pharmacol. 2006;1:119-128.
    • (2006) Curr Clin Pharmacol , vol.1 , pp. 119-128
    • Zhou, S.1
  • 3
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet. 1980;32:651-662. (Pubitemid 10061685)
    • (1980) American Journal of Human Genetics , vol.32 , Issue.5 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 4
    • 0027524983 scopus 로고
    • Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia
    • Lennard L, Gibson BES, Nicole T, et al. Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia. Arch Dis Child. 1993;69:577-579. (Pubitemid 23355853)
    • (1993) Archives of Disease in Childhood , vol.69 , Issue.5 , pp. 577-579
    • Lennard, L.1    Gibson, B.E.S.2    Nicole, T.3    Lilleyman, J.S.4
  • 5
    • 67349087340 scopus 로고    scopus 로고
    • TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients
    • Kurzawski M, Dziewanowski K, Lener A, et al. TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients. Eur J Clin Pharmacol. 2009;65:533-540.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 533-540
    • Kurzawski, M.1    Dziewanowski, K.2    Lener, A.3
  • 6
    • 38549151340 scopus 로고    scopus 로고
    • Characterization of the inosine triphosphatase (ITPA) gene: Haplotype structure, haplotype-phenotype correlation and promoter function
    • DOI 10.1097/FTD.0b013e318161a21a, PII 0000769120080200000004
    • Von Ahsen N, Oellerich M, Armstrong VW. Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotypephenotype correlation and promoter function. Ther Drug Monit. 2008; 30:16-22. (Pubitemid 351161094)
    • (2008) Therapeutic Drug Monitoring , vol.30 , Issue.1 , pp. 16-22
    • Von Ahsen, N.1    Oellerich, M.2    Armstrong, V.W.3
  • 7
  • 8
    • 67651163895 scopus 로고    scopus 로고
    • Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease
    • Smith MA, Marinaki AM, Arenas M, et al. Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease. Aliment Pharmacol Ther. 2009;30:375-384.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 375-384
    • Smith, M.A.1    Marinaki, A.M.2    Arenas, M.3
  • 9
    • 0029900435 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH)
    • DOI 10.1006/geno.1996.0262
    • Xu P, Huecksteadt TP, Hoidal JR. Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH). Genomics. 1996; 34:173-180. (Pubitemid 26172841)
    • (1996) Genomics , vol.34 , Issue.2 , pp. 173-180
    • Xu, P.1    Huecksteadt, T.P.2    Hoidal, J.R.3
  • 10
    • 0021028642 scopus 로고
    • Inhibition of first-pass metabolism in cancer chemotherapy: Interaction of 6-mercaptopurine and allopurinol
    • Zimm S, Collins JM, O'Neill D, et al. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol. Clin Pharmacol Ther. 1983;34:810-817. (Pubitemid 14219930)
    • (1983) Clinical Pharmacology and Therapeutics , vol.34 , Issue.6 , pp. 810-817
    • Zimm, S.1    Collins, J.M.2    O'Neill, D.3
  • 11
    • 0029987936 scopus 로고    scopus 로고
    • Detection and identification of 6-methylmercapto-8-hydroxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration
    • Keuzenkamp-Jansen CW, van Baal JM, De Abreu RA, et al. Detection and identification of 6-methylmercapto-8-hydoxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration. Clin Chem. 1996;42:380-386. (Pubitemid 26080922)
    • (1996) Clinical Chemistry , vol.42 , Issue.3 , pp. 380-386
    • Keuzenkamp-Jansen, C.W.1    Van Baal, J.M.2    De Abreu, R.A.3    De Jong, J.G.N.4    Zuiderent, R.5    Trijbels, J.M.F.6
  • 13
    • 42049122605 scopus 로고    scopus 로고
    • Role of pharmacogenetics of immunosuppressive drugs in organ transplantation
    • DOI 10.1097/FTD.0b013e31816babef, PII 0000769120080400000003
    • Thervet E, Anglicheau D, Legendre C, et al. Role of pharmacogenetics of immunosuppressive drugs in organ transplantation. Ther Drug Monit. 2008;30:143-150. (Pubitemid 351521640)
    • (2008) Therapeutic Drug Monitoring , vol.30 , Issue.2 , pp. 143-150
    • Thervet, E.1    Anglicheau, D.2    Legendre, C.3    Beaune, P.4
  • 14
    • 45849107951 scopus 로고    scopus 로고
    • Clinical pharmacology and pharmacogenetics of thiopurines
    • Sahasranaman S, Howard D, Roy S. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008;64: 753-767.
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 753-767
    • Sahasranaman, S.1    Howard, D.2    Roy, S.3
  • 16
    • 33645885609 scopus 로고    scopus 로고
    • Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease
    • Stocco G, Martelossi S, Sartor F, et al. Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease. Dig Dis Sci. 2006;51:474-479.
    • (2006) Dig Dis Sci , vol.51 , pp. 474-479
    • Stocco, G.1    Martelossi, S.2    Sartor, F.3
  • 17
    • 78249243846 scopus 로고    scopus 로고
    • The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease
    • Ban H, Andoh A, Imaeda H, et al. The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease. J Gastroenterol. 2010;45:1014-1021.
    • (2010) J Gastroenterol , vol.45 , pp. 1014-1021
    • Ban, H.1    Andoh, A.2    Imaeda, H.3
  • 18
    • 79955904447 scopus 로고    scopus 로고
    • Evidence for a functional genetic polymorphism of the Rho-GTPase Rac1.Implication in azathioprine response?
    • Bourgine J, Garat A, Allorge D, et al. Evidence for a functional genetic polymorphism of the Rho-GTPase Rac1. Implication in azathioprine response? Pharmacogenet Genomics. 2011;21:313-324.
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 313-324
    • Bourgine, J.1    Garat, A.2    Allorge, D.3
  • 19
    • 80051788056 scopus 로고    scopus 로고
    • Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease
    • Shipkova M, Franz J, Abe M, et al. Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease. Ther Drug Monit. 2011;33:321-328.
    • (2011) Ther Drug Monit , vol.33 , pp. 321-328
    • Shipkova, M.1    Franz, J.2    Abe, M.3
  • 20
    • 34848819742 scopus 로고    scopus 로고
    • In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase
    • Rashidi MR, Beedham C, Smith JS, et al. In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase. Drug Metab Pharmacokinet. 2007;22:299-306.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 299-306
    • Rashidi, M.R.1    Beedham, C.2    Smith, J.S.3
  • 21
    • 0026346078 scopus 로고
    • Human liver xanthine oxidase: Nature and extent of individual variation
    • Guerciolini R, Szumlanski C, Weinshilboum RM. Human liver xanthine oxidase: nature and extent of individual variation. Clin Pharmacol Ther. 1991;50:663-672.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 663-672
    • Guerciolini, R.1    Szumlanski, C.2    Weinshilboum, R.M.3
  • 22
    • 77956961565 scopus 로고    scopus 로고
    • Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase
    • Kudo M, Sasaki T, Ishikawa M, et al. Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase. Drug Metab Pharmacokinet. 2010;25:361-366.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 361-366
    • Kudo, M.1    Sasaki, T.2    Ishikawa, M.3
  • 23
    • 78951470115 scopus 로고    scopus 로고
    • Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene
    • Kudo M, Sasaki T, Ishikawa M, et al. Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene. Drug Metab Pharmacokinet. 2010;25:599-604.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 599-604
    • Kudo, M.1    Sasaki, T.2    Ishikawa, M.3
  • 24
    • 0022504824 scopus 로고
    • The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver
    • Ikegami T, Nishino T. The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver. Arch Biochem Biophys. 1986;247:254-260. (Pubitemid 16077528)
    • (1986) Archives of Biochemistry and Biophysics , vol.247 , Issue.2 , pp. 254-260
    • Ikegami, T.1    Nishino, T.2
  • 26
    • 73649092728 scopus 로고    scopus 로고
    • Human Genetic variation, Population Pharmacokinetic-dynamic models, Bayesian feedback control, and maximally precise Individualized drug dosage regimens
    • Jelliffe R, Schumitzky A, Bayard D, et al. Human Genetic variation, Population Pharmacokinetic-dynamic models, Bayesian feedback control, and maximally precise Individualized drug dosage regimens. Curr Pharmacogenomics Person Med. 2009;7:249-262.
    • (2009) Curr Pharmacogenomics Person Med , vol.7 , pp. 249-262
    • Jelliffe, R.1    Schumitzky, A.2    Bayard, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.