Detection and identification of 6-methylmercapto-8-hydroxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration

Clinical Chemistry

Volumn 42, Issue 3, 1996, Pages 380-386

  Keuzenkamp Jansen, Carin W ^a   Van Baal, John M ^a   De Abreu, Ronney A ^a   De Jong, Jan G N ^a   Zuiderent, Richard ^a   Trijbels, J M Frans ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

acute lymphoblastic leukemia; drug metabolism; methotrexate; thiouric acid

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; MERCAPTOPURINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG EXCRETION; DRUG MEGADOSE; GAS CHROMATOGRAPHY; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; KIDNEY CLEARANCE; MASS SPECTROMETRY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0029987936     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/42.3.380     Document Type: Article

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