Measurement of liver iron overload: Noninvasive calibration of MRI-R 2* by magnetic iron detector susceptometer

Magnetic Resonance in Medicine

Volumn 67, Issue 6, 2012, Pages 1782-1786

  Gianesin, B ^a,b   Zefiro, D ^a   Musso, M ^a   Rosa, A ^a   Bruzzone, C ^c   Balocco, M ^a   Carrara, P ^a   Bacigalupo, L ^a   Banderali, S ^a   Rollandi, G A ^a   Gambaro, M ^a   Marinelli, M ^b,c   Forni, G L ^a  

^a GALLIERA HOSPITAL   (Italy)

^b INFN SEZIONE DI GENOVA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

liver iron overload; magnetic iron detector; magnetic susceptometry; MRI

Indexed keywords

BIOPSY; CALIBRATION; DISEASE CONTROL; MAGNETIC RESONANCE IMAGING; MAGNETISM; TISSUE;

IRON ACCUMULATION; IRON CONCENTRATIONS; IRON OVERLOADS; LINEAR CALIBRATION; MAGNETIC SUSCEPTOMETRY; NONINVASIVE TECHNIQUE; OBSERVATIONAL STUDY; TRANSVERSE RELAXATION RATE;

IRON;

IRON;

ADOLESCENT; ADULT; AGED; ANALYTICAL EQUIPMENT; ARTICLE; CALCULATION; CALIBRATION; CHILD; DATA ANALYSIS SOFTWARE; EVALUATION; FEMALE; HUMAN; IMAGE ANALYSIS; INTERMETHOD COMPARISON; IRON OVERLOAD; LIVER BIOPSY; LIVER LEVEL; MAGNETIC IRON DETECTOR SUSCEPTOMETER; MAGNETIC IRON DETECTOR SUSCEPTOMETRY; MAGNETISM; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; NON INVASIVE MEASUREMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OBSERVATIONAL STUDY; RETROSPECTIVE STUDY; SCHOOL CHILD;

EID: 84861228543     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.23148     Document Type: Article

References (37)

1. Brittenham GM, Badman DG,. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Workshop. Noninvasive measurement of iron: report of an NIDDK workshop. Blood 2003; 101: 15-19.
2. Worwood M,. The laboratory assessment of iron status-an update. Clin Chim Acta 1997; 259: 3-23.
3. Olivé A, Juncà J,. Elevated serum ferritin levels: associated diseases and clinical significance. Am J Med 1996; 101: 120-121.
4. Angelucci E, Brittenham GM, McLaren CE, Ripalti M, Baronciani D, Giardni C, Galimberti M, Polchi P, Lucarelli G,. Hepatic iron concentration and total body iron stores in thalassemia major. N Engl J Med 2000; 343: 327-331.
5. Maggio A, Hoffbrand AV,. Clinical aspect and therapy of thalassemia. Firenze, Italia: Società Editrice Europea di Nicodemo Maggiulli & C; 2004.
6. Butensky E, Fischer R, Hudes M, Schumacher L, Williams R, Moyer TP, Vichinsky E, Harmatz P,. Variability in hepatic iron concentration in percutaneous needle biopsy specimens from patients with transfusional hemosiderosis. Am J Clin Pathol 2005; 123: 146-152.
7. St Pierre TG, Clark PR, Chua-Anusorn W, Fleming AJ, Jeffrey GP, Olynyk JK, Pootrakul P, Robins E, Lindeman R,. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 2005; 105: 855-861.
8. Wood JC, Enriquez C, Ghugre N, Tyzka JM, Carson S, Nelson MD, Coates TD,. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood 2005; 106: 1460-1465.
9. Angelucci E, Giovagnoni A, Valeri G, Paci E, Ripalti M, Muretto P, McLauren C, Brittenham GM, Lucarelli G,. Limitations of magnetic resonance imaging in measurement of hepatic iron. Blood 1997; 90: 4736-4742.
10. Gandon Y, Olivié D, Guyader D, Aubé C, Oberti F, Sebille V, Deugnier Y,. Non-invasive assessment of hepatic iron stores by MRI. Lancet 2004; 363: 357-362.
11. Carneiro AA, Fernandes JP, de Araujo DB, Elias J Jr, Martinelli AL, Covas DT, Zago MA, Angulo IL, St Pierre TG, Baffa O,. Liver iron concentration evaluated by two magnetic methods: magnetic resonance imaging and magnetic susceptometry. Magn Reson Med 2005; 54: 122-128.
12. Brittenham GM, Farrell DE, Harris JW, Feldman ES, Danish EH, Muir WA, Tripp JH, Bellon EM,. Magnetic-susceptibility measurement of human iron stores. N Engl J Med 1982; 307: 1671-1675.
13. Paulson DN, Fagaly RL, Toussaint RM, Fischer R,. Biomagnetic susceptometer with SQUID instrumentation. IEEE Trans Magn 1991; 27: 3249-3252.
14. Brittenham GM, Sheth S, Allen CJ, Farrell DE,. Noninvasive methods for quantitative assessment of transfusional iron overload in sickle cell disease. Semin Hematol 2001; 38: 37-56.
15. Farrell DE, Tripp JH, Zanzucchi PE, Harris JW, Brittenham GM, Muirl WA,. Magnetic measurement of human iron stores. IEEE Trans Magn 1980; 26: 818-823.
16. Nielsen P, Fischer R, Engelhardt R, Tondüry P, Gabbe EE, Janka GE,. Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone. Br J Haematol 1995; 91: 827-833.
17. Fischer R, Eich E, Engelhardt R, Heinrich HC, Kessler M, Nielsen P,. The calibration problem in liver iron susceptometry. In:, Williamson SJ, editor. Advances in biomagnetism. New York: Plenum; 1989. pp 501-504.
18. Fischer R,. Large-scale study in thalassemia using biomagnetic liver susceptometry. In: Proceedings of the 11th International conference on Biomagnetism, Sendai, Japan, 1998.
19. Marinelli M, Cuneo S, Gianesin B, Lavagetto A, Lamagna M, Oliveri E, Sobrero G, Terenzani L, Forni GL,. Non-invasive measurement of iron overload in the human body. IEEE Trans Appl Supercond 2006; 16: 1513-1518.
20. Marinelli M, Gianesin B, Lamagna M, Lavagetto A, Oliveri E, Saccone ML, Sobrero G, Terenzani L, Forni GL,. Whole liver iron overload measurement by a non cryogenic magnetic susceptometer. Int Congr Ser 2007; 1300: 299-302.
21. Marinelli M, Gianesin B, Avignolo C, Minganti V, Parodi S,. Iron overload detection in rats by means of a susceptometer operating at room temperature. Phys Med Biol 2008; 53: 6849-6860.
22. Marinelli M, Gianesin B, Balocco M, Beruto P, Bruzzone C, Carrara P, Gallusi P, Macco A, Musso M, Oliveri E, Pelucchi S, Sobrero G, Villa R, Forni GL,. Total iron-overload measurement in the human liver region by the magnetic iron detector. IEEE Trans Magn 2010; 57: 2295-2302.
23. Baldassarre L, Barla A, Gianesin B, Marinelli M,. Vector valued regression for iron overload estimation. In: Proceedings of the 19th International Conference on Pattern Recognition, ICPR, Florida, USA, 2008.
24. Gianesin B, Baldassarre L,. Computational models for estimating liver iron overload with the magnetic iron detector. In: Proceedings of the 4th Conference on Advanced Engineering Computing and Application in Sciences, IARIA, Florence, Italy, 2010.
25. Fischer R, Piga A, Harmatz P, Nielsen P,. Monitoring long-term efficacy of iron chelation treatment with biomagnetic liver susceptometry. Ann NY Acad Sci 2005; 1054: 350-357.
26. Fischer R, Harmatz P, Nielsen P, Cappellini MD,. Does liver biopsy overestimate liver iron concentration? Blood 2006; 108: 1775-1776.
27. Cohen AR, Glimm E, Porter JB,. Effect of transfusional iron intake on response to chelation therapy in β-thalassemia major. Blood 2008; 111: 583-587.
28. Anderson LJ, Holden S, Davis B, Prescott E, Charrier CC, Bunce NH, Firmin DN, Wonke B, Porter J, Walker JM, Pennell DJ,. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001; 22: 2171-2179.
29. Zuyderhoudt FM, Hengeveld P, van Gool J, Jorning GG,. A method for measurement of liver iron fractions in needle biopsy specimens and some results in acute liver disease. Clin Chim Acta 1978; 86: 313-321.
30. Ghugre NR, Wood JC,. Relaxivity-iron calibration in hepatic iron overload: probing underlying biophysical mechanisms using a Monte Carlo model. Magn Reson Med 2011; 65: 837-847.
31. Chan YL, Li CK, Chik KW, Law MY, Howard R,. Liver volume in thalassaemia major: relationship with body weight, serum ferritin, and liver function. Pediatr Radiol 2005; 35: 165-168
32. Vauthey JN, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, Lerut J, Materne R, Wang X, Encarnacion A, Herron D, Mathey C, Ferrari G, Charnsangavej C, Do KA, Denys A,. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl 2002; 8: 233-240.
33. Bland JM, Altman DG,. Statistical methods for assigning agreement between two methods of clinical measurement. Lancet 1986; 8476: 307-310.
34. Bothwell T, MacPhail A,. Hereditary hemochromatosis: etiologic, pathologic, and clinical aspects. Semin Hematol 1988; 35: 55-71.
35. Michaelis L, Coryell CD, Granick S,. Ferritin III: the magnetic properties of ferritin and some other colloidal ferric compounds. J Biol Chem 1943; 148: 463-480.
36. Shoden A, Richter GW,. On the extraction and staining of ferritin. Folia Haematol (Frankf) 1960; 4: 180-183.
37. Fernández-Seara MA, Wehrli FW,. Postprocessing technique to correct for background gradients in image-based R*(2) measurements. Magn Reson Med 2000; 44: 358-366.