The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles

Biomaterials

Volumn 33, Issue 22, 2012, Pages 5584-5592

  Jang, Eue Soon ^a,c   Shin, June Ho ^a   Ren, Gang ^a   Park, Mi Jin ^c   Cheng, Kai ^a   Chen, Xiaoyuan ^b   Wu, Joseph C ^a   Sunwoo, John B ^a   Cheng, Zhen ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^c Kumoh National Institute of Technology   (South Korea)

Author keywords

Fe 3O 4 SiO 2 core shell nanoparticles; Magnetic field guided cell control; Multifunctional nanoparticles; Natural killer cells; Tumor killing activity

Indexed keywords

CELL CONTROL; CELL MANIPULATION; CLINICAL TREATMENTS; CORE/SHELL NANOPARTICLES; ENHANCED INFILTRATION; EXTERNAL MAGNETIC FIELD; MAGNETIC NANOPARTICLES; MULTI-FUNCTIONAL NANOPARTICLES; NATURAL KILLER CELLS; REDUCED TOXICITY; RELATIVE RATIOS; TARGET SITES; TUMOR SITE;

CELLS; CYTOLOGY; ELECTROMAGNETIC FIELD EFFECTS; MAGNETIC FIELDS; NANOPARTICLES; TUMORS;

MOLECULAR BIOLOGY;

IRON OXIDE; MAGNETIC NANOPARTICLE; NANOSHELL; SILICON DIOXIDE;

ARTICLE; CELL ACTIVITY; CELL INFILTRATION; CELL MANIPULATION; CELL MOTION; CELL SELECTION; CELL STRAIN; CONCENTRATION (PARAMETERS); CYTOTOXICITY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VIVO STUDY; MAGNETIC FIELD; NATURAL KILLER CELL; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ANIMALS; CELL LINE; CELL MOVEMENT; IMMUNOMAGNETIC SEPARATION; KILLER CELLS, NATURAL; MAGNETIC FIELDS; MAGNETITE NANOPARTICLES; NEOPLASMS, EXPERIMENTAL; RATS; TREATMENT OUTCOME;

EID: 84861225600     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.04.041     Document Type: Article

References (39)

1. Gao J., Chen K., Miao Z., Ren G., Chen X., Gambhir S.S., et al. Affibody-based nanoprobes for HER2-expressing cell and tumor imaging. Biomaterials 2011, 32:2141-2148.
2. Jokerst J.V., Miao Z., Zavaleta C., Cheng Z., Gambhir S.S. Affibody-functionalized gold-silica nanoparticles for Raman molecular imaging of the epidermal growth factor receptor. Small 2011, 7:625-633.
3. Smith B.R., Cheng Z., De A., Rosenberg J., Gambhir S.S. Dynamic visualization of RGD-quantum dot binding to tumor neovasculature and extravasation in multiple living mouse models using intravital microscopy. Small 2010, 6:2222-2229.
4. Huang J., Bu L., Xie J., Chen K., Cheng Z., Chen X. Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles. ACS Nano 2010, 4:7151-7160.
5. Gao J., Chen K., Xie R., Xie J., Lee S., Cheng Z., et al. Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging. Small 2010, 6:256-261.
6. Choi H.S., Liu W., Misra P., Tanaka E., Zimmer J.P., Ipe B.I., et al. Renal clearance of quantum dots. Nat Biotechnol 2007, 25:1165-1170.
7. Bhabra G., Sood A., Fisher B., Cartwright L., Saunders M., Evans W.H., et al. Nanoparticles can cause DNA damage across a cellular barrier. Nat Nanotechnol 2009, 4:876-883.
8. Mahmoudi M., Azadmanesh K., Shokrgozar M.A., Journeay W.S., Laurent S. Protein-nanoparticle interactions: opportunities and challenges. Chem Rev 2011, 111:5610-5637.
9. Schipper M.L., Lyer G., Koh A.L., Cheng Z., Ebenstein Y., Aharoni A., et al. Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small 2009, 5:126-134.
10. Huang J., Xie J., Chen K., Bu L., Lee S., Cheng Z., et al. HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging. Chem Commun 2010, 46:6684-6686.
11. Orr M.T., Lanier L.L. Natural killer cell education and tolerance. Cell 2010, 142:847-856.
12. Höglund P., Brodin P. Current perspectives of natural killer cell education by MHC class I molecules. Nat Rev Immunol 2010, 10:724-734.
13. Groh V., Wu J., Yee C., Spies T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 2002, 419:734-748.
14. Ishigami S., Natsugoe S., Tokuda K., Nakajo A., Che X., Iwashige H., et al. Prognostic value of intratumoral natural killer cells in gastric carcinoma. Cancer 2000, 88:577-583.
15. Yoon T.J., Yu K.N., Kim E., Kim J.S., Kim B.G., Yun S.H., et al. Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomaterials. Small 2006, 2:209-215.
16. Amendola V., Meneghetti M., Granozzi G., Agnoli S., Polizzi S., Riello P., et al. Top-down synthesis of multifunctional iron oxide nanoparticles for macrophage labelling and manipulation. J Mater Chem 2011, 21:3803-3813.
17. Galanzha E.I., Shashkov E.V., Kelly T., Kim J.W., Yang L., Zharov V.P. In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells. Nat Nanotechnol 2009, 4:855-860.
18. Riegler J., Allain B., Cook R.J., Lythgoe M.F., Pankhurs Q.A. Magnetically assisted delivery of cells using a magnetic resonance imaging system. J Phys D: Appl Phys 2011, 44. 055001.
19. Pan Y., Long M.J.C., Li X., Shi J., Hedstrom L., Xu B. Glutathione (GSH)-decorated magnetic nanoparticles for binding glutathione-S-transferase (GST) fusion protein and manipulating live cells. Chem Sci 2011, 2:945-948.
20. Riegler J., Wells J.A., Kyrtatos P.G., Price A.N., Pankhurst Q.A., Lythgoe M.F. Targeted magnetic delivery and tracking of cells using a magnetic resonance imaging system. Biomaterials 2010, 31:5366-5371.
21. Caligiuri M.A. Human natural killer cells. Blood 2008, 112:461-469.
22. Fujisaki H., Kakuda H., Shimasaki N., Imai C., Ma J., Lockey T., et al. Expansion of highly cytotoxic human natural killer cells for cancer cell therapy. Cancer Res 2009, 69:4010-4017.
23. Mahmoudi M., Hosseinkhani H., Hosseinkhani M., Boutry S., Simchi A., Journeay W.S., et al. Effect of nanoparticles on the cell life cycle. Chem Rev 2011, 111:253-280.
24. Yi D.K., Lee S.S., Papaefthymiou G.C., Ying J.Y. Synthesis and applications of magnetic nanocomposite catalysts. Chem Mater 2006, 18:614-619.
25. Yang Y., Jing L., Yu X., Yan D., Gao M. Coating aqueous quantum dots with silica via reverse microemulsion method: toward size-controllable and robust fluorescent nanoparticles. Chem Mater 2007, 19:4123-4128.
26. Koole R., Schooneveld M.M., Hilhort J., Donegá C.M., Hart D.C., Blaaderen A., et al. On the incorporation mechanism of hydrophobic quantum dots in silica spheres by a reverse microemulsion method. Chem Mater 2008, 20:2503-2512.
27. Kim J., Kim H.S., Lee N., Kim T., Kim H., Yu T., et al. Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew Chem Int Ed 2008, 47:8438-8441.
28. Stöber W., Fink A., Bohn E. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Int Sci 1968, 26:62-69.
29. Lu F., Wu S.H., Hung Y., Mou C.Y. Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles. Small 2009, 5:1408-1413.
30. Bagwe B.P., Hilliard L.R., Tan W. Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding. Langmuir 2006, 22:4357-4362.
31. Cha E.J., Jang E.S., Sun I.C., Lee I.J., Ko J.H., Kim Y.I. Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles. J Control Release 2011, 155:152-158.
32. Kievit F.M., Veiseh O., Bhattarai N., Fang C., Gunn J.W., Lee D., et al. PEI-PEG-chitosan-copolymer-coated iron oxide nanoparticles for safe gene delivery: synthesis, complexation, and transfection. Adv Funct Mater 2009, 19:2244-2251.
33. Arsianti M., Lim M., Marquis C.P., Amal R. Assembly of polyethylenimine-based magnetic iron oxide vectors: insights into gene delivery. Langmuir 2010, 26:7314-7326.
34. Lee S., Cha E.J., Park K., Lee S.Y., Hong J.K., Sun I.C., et al. A near-infrared-fluorescence-quenched gold-nanoparticle imaging probe for in vivo drug screening and protease activity determination. Angew Chem Int Ed 2008, 120:2846-2849.
35. Cho Y.S., Yoon T.J., Jang E.S., Hong K.S., Lee S.Y., Kim O.R., et al. Cetuximab-conjugated magneto-fluorescent silica nanoparticles for in vivo colon cancer targeting and imaging. Cancer Lett 2010, 299:63-71.
36. Nel A.E., Mädler L., Velegol D., Xia T., Hoek E.M.V., Somasundaran P., et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 2009, 8:543-557.
37. McEver R.P., Zhu C. Rolling cell adhesion. Annu Rev Cell Dev Biol 2010, 26:363-396.
38. Lee J.H., Huh Y.M., Jun Y.W., Jang J.T., Song H.T., Kim S., et al. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat Med 2007, 13:95-99.
39. Lee J.H., Jang J.T., Choi J.S., Moon S.H., Noh S.H., Kim J.W., et al. Exchange-coupled magnetic nanoparticles for efficient heat induction. Nat Nanotechnol 2011, 6:418-422.