-
1
-
-
0022876328
-
Huntington's disease. Pathogenesis and management
-
Martin J.B., Gusella J.F. Huntington's disease. Pathogenesis and management. N. Engl. J. Med. 1986, 315:1267-1276.
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 1267-1276
-
-
Martin, J.B.1
Gusella, J.F.2
-
2
-
-
0001589776
-
Differential loss of striatal projection neurons in Huntington disease
-
Reiner A., Albin R.L., Anderson K.D., D'Amato C.J., Penney J.B., Young A.B. Differential loss of striatal projection neurons in Huntington disease. Proc. Natl. Acad. Sci. USA 1988, 85:5733-5737.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5733-5737
-
-
Reiner, A.1
Albin, R.L.2
Anderson, K.D.3
D'Amato, C.J.4
Penney, J.B.5
Young, A.B.6
-
3
-
-
0038476184
-
Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis
-
Rosas H.D., Koroshetz W.J., Chen Y.I., Skeuse C., Vangel M., Cudkowicz M.E., Caplan K., Marek K., Seidman L.J., Makris N., Jenkins B.G., Goldstein J.M. Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis. Neurology 2003, 60:1615-1620.
-
(2003)
Neurology
, vol.60
, pp. 1615-1620
-
-
Rosas, H.D.1
Koroshetz, W.J.2
Chen, Y.I.3
Skeuse, C.4
Vangel, M.5
Cudkowicz, M.E.6
Caplan, K.7
Marek, K.8
Seidman, L.J.9
Makris, N.10
Jenkins, B.G.11
Goldstein, J.M.12
-
4
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983. The Huntington's Disease Collaborative Research Group.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
5
-
-
77955643169
-
Molecular mechanisms and potential therapeutical targets in Huntington's disease
-
Zuccato C., Valenza M., Cattaneo E. Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiol. Rev. 2010, 90:905-981.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 905-981
-
-
Zuccato, C.1
Valenza, M.2
Cattaneo, E.3
-
6
-
-
79957748358
-
Milestones in huntington disease
-
Shoulson I., Young A.B. Milestones in huntington disease. Mov. Disord. 2011, 26:1127-1133.
-
(2011)
Mov. Disord.
, vol.26
, pp. 1127-1133
-
-
Shoulson, I.1
Young, A.B.2
-
7
-
-
79955955066
-
Proteasomal dysfunction in aging and Huntington disease
-
Li X.J., Li S. Proteasomal dysfunction in aging and Huntington disease. Neurobiol. Dis. 2011, 43:4-8.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 4-8
-
-
Li, X.J.1
Li, S.2
-
8
-
-
79551554590
-
The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease
-
Munoz-Sanjuan I., Bates G.P. The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease. J. Clin. Invest. 2011, 121:476-483.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 476-483
-
-
Munoz-Sanjuan, I.1
Bates, G.P.2
-
9
-
-
79551518229
-
Energy deficit in Huntington disease: why it matters
-
Mochel F., Haller R.G. Energy deficit in Huntington disease: why it matters. J. Clin. Invest. 2011, 121:493-499.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 493-499
-
-
Mochel, F.1
Haller, R.G.2
-
11
-
-
84861222373
-
The recycling endosome and its role in neurological disorders
-
Li X., Difiglia M. The recycling endosome and its role in neurological disorders. Prog. Neurobiol. 2011.
-
(2011)
Prog. Neurobiol.
-
-
Li, X.1
Difiglia, M.2
-
12
-
-
78650764923
-
Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity
-
Pellerin L. Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity. Diabetes Metab. 2010, 36(Suppl 3):S59-S63.
-
(2010)
Diabetes Metab.
, vol.36
, Issue.SUPPL. 3
-
-
Pellerin, L.1
-
13
-
-
0019991784
-
Cerebral metabolism and atrophy in Huntington's disease determined by 18FDG and computed tomographic scan
-
Kuhl D.E., Phelps M.E., Markham C.H., Metter E.J., Riege W.H., Winter J. Cerebral metabolism and atrophy in Huntington's disease determined by 18FDG and computed tomographic scan. Ann. Neurol. 1982, 12:425-434.
-
(1982)
Ann. Neurol.
, vol.12
, pp. 425-434
-
-
Kuhl, D.E.1
Phelps, M.E.2
Markham, C.H.3
Metter, E.J.4
Riege, W.H.5
Winter, J.6
-
14
-
-
0022641113
-
Positron emission tomography in the early diagnosis of Huntington's disease
-
Hayden M.R., Martin W.R., Stoessl A.J., Clark C., Hollenberg S., Adam M.J., Ammann W., Harrop R., Rogers J., Ruth T., et al. Positron emission tomography in the early diagnosis of Huntington's disease. Neurology 1986, 36:888-894.
-
(1986)
Neurology
, vol.36
, pp. 888-894
-
-
Hayden, M.R.1
Martin, W.R.2
Stoessl, A.J.3
Clark, C.4
Hollenberg, S.5
Adam, M.J.6
Ammann, W.7
Harrop, R.8
Rogers, J.9
Ruth, T.10
-
15
-
-
0022553413
-
PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline
-
Young A.B., Penney J.B., Starosta-Rubinstein S., Markel D.S., Berent S., Giordani B., Ehrenkaufer R., Jewett D., Hichwa R. PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline. Ann. Neurol. 1986, 20:296-303.
-
(1986)
Ann. Neurol.
, vol.20
, pp. 296-303
-
-
Young, A.B.1
Penney, J.B.2
Starosta-Rubinstein, S.3
Markel, D.S.4
Berent, S.5
Giordani, B.6
Ehrenkaufer, R.7
Jewett, D.8
Hichwa, R.9
-
16
-
-
0025153344
-
Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease
-
Kuwert T., Lange H.W., Langen K.J., Herzog H., Aulich A., Feinendegen L.E. Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain 1990, 113(Pt 5):1405-1423.
-
(1990)
Brain
, vol.113
, Issue.PART. 5
, pp. 1405-1423
-
-
Kuwert, T.1
Lange, H.W.2
Langen, K.J.3
Herzog, H.4
Aulich, A.5
Feinendegen, L.E.6
-
17
-
-
0026508939
-
Cortical glucose metabolism in Huntington's disease
-
Martin W.R., Clark C., Ammann W., Stoessl A.J., Shtybel W., Hayden M.R. Cortical glucose metabolism in Huntington's disease. Neurology 1992, 42:223-229.
-
(1992)
Neurology
, vol.42
, pp. 223-229
-
-
Martin, W.R.1
Clark, C.2
Ammann, W.3
Stoessl, A.J.4
Shtybel, W.5
Hayden, M.R.6
-
18
-
-
33747777842
-
Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease
-
Ciarmiello A., Cannella M., Lastoria S., Simonelli M., Frati L., Rubinsztein D.C., Squitieri F. Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J. Nucl. Med. 2006, 47:215-222.
-
(2006)
J. Nucl. Med.
, vol.47
, pp. 215-222
-
-
Ciarmiello, A.1
Cannella, M.2
Lastoria, S.3
Simonelli, M.4
Frati, L.5
Rubinsztein, D.C.6
Squitieri, F.7
-
19
-
-
0041691176
-
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats
-
Menalled L.B., Sison J.D., Dragatsis I., Zeitlin S., Chesselet M.F. Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats. J. Comp. Neurol. 2003, 465:11-26.
-
(2003)
J. Comp. Neurol.
, vol.465
, pp. 11-26
-
-
Menalled, L.B.1
Sison, J.D.2
Dragatsis, I.3
Zeitlin, S.4
Chesselet, M.F.5
-
20
-
-
77950682093
-
Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease
-
Li X., Valencia A., Sapp E., Masso N., Alexander J., Reeves P., Kegel K.B., Aronin N., Difiglia M. Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease. J. Neurosci. 2010, 30:4552-4561.
-
(2010)
J. Neurosci.
, vol.30
, pp. 4552-4561
-
-
Li, X.1
Valencia, A.2
Sapp, E.3
Masso, N.4
Alexander, J.5
Reeves, P.6
Kegel, K.B.7
Aronin, N.8
Difiglia, M.9
-
21
-
-
70349785084
-
Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease
-
Li X., Sapp E., Chase K., Comer-Tierney L.A., Masso N., Alexander J., Reeves P., Kegel K.B., Valencia A., Esteves M., Aronin N., Difiglia M. Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease. Neurobiol. Dis. 2009, 36:374-383.
-
(2009)
Neurobiol. Dis.
, vol.36
, pp. 374-383
-
-
Li, X.1
Sapp, E.2
Chase, K.3
Comer-Tierney, L.A.4
Masso, N.5
Alexander, J.6
Reeves, P.7
Kegel, K.B.8
Valencia, A.9
Esteves, M.10
Aronin, N.11
Difiglia, M.12
-
22
-
-
0029850677
-
Rab11 regulates recycling through the pericentriolar recycling endosome
-
Ullrich O., Reinsch S., Urbe S., Zerial M., Parton R.G. Rab11 regulates recycling through the pericentriolar recycling endosome. J. Cell Biol. 1996, 135:913-924.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 913-924
-
-
Ullrich, O.1
Reinsch, S.2
Urbe, S.3
Zerial, M.4
Parton, R.G.5
-
23
-
-
71949120013
-
Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity
-
Li X., Standley C., Sapp E., Valencia A., Qin Z.H., Kegel K.B., Yoder J., Comer-Tierney L.A., Esteves M., Chase K., Alexander J., Masso N., Sobin L., Bellve K., Tuft R., Lifshitz L., Fogarty K., Aronin N., DiFiglia M. Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity. Mol. Cell. Biol. 2009, 29:6106-6116.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 6106-6116
-
-
Li, X.1
Standley, C.2
Sapp, E.3
Valencia, A.4
Qin, Z.H.5
Kegel, K.B.6
Yoder, J.7
Comer-Tierney, L.A.8
Esteves, M.9
Chase, K.10
Alexander, J.11
Masso, N.12
Sobin, L.13
Bellve, K.14
Tuft, R.15
Lifshitz, L.16
Fogarty, K.17
Aronin, N.18
DiFiglia, M.19
-
24
-
-
26444441008
-
HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism
-
Seong I.S., Ivanova E., Lee J.M., Choo Y.S., Fossale E., Anderson M., Gusella J.F., Laramie J.M., Myers R.H., Lesort M., MacDonald M.E. HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum. Mol. Genet. 2005, 14:2871-2880.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2871-2880
-
-
Seong, I.S.1
Ivanova, E.2
Lee, J.M.3
Choo, Y.S.4
Fossale, E.5
Anderson, M.6
Gusella, J.F.7
Laramie, J.M.8
Myers, R.H.9
Lesort, M.10
MacDonald, M.E.11
-
25
-
-
34548399406
-
Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism
-
Lee J.M., Ivanova E.V., Seong I.S., Cashorali T., Kohane I., Gusella J.F., MacDonald M.E. Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. PLoS Genet. 2007, 3:e135.
-
(2007)
PLoS Genet.
, vol.3
-
-
Lee, J.M.1
Ivanova, E.V.2
Seong, I.S.3
Cashorali, T.4
Kohane, I.5
Gusella, J.F.6
MacDonald, M.E.7
-
26
-
-
0032568657
-
Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes
-
Ren M., Xu G., Zeng J., De Lemos-Chiarandini C., Adesnik M., Sabatini D.D. Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes. Proc. Natl. Acad. Sci. USA 1998, 95:6187-6192.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6187-6192
-
-
Ren, M.1
Xu, G.2
Zeng, J.3
De Lemos-Chiarandini, C.4
Adesnik, M.5
Sabatini, D.D.6
-
27
-
-
1842734654
-
Glucose transporter expression in the central nervous system: relationship to synaptic function
-
McEwen B.S., Reagan L.P. Glucose transporter expression in the central nervous system: relationship to synaptic function. Eur. J. Pharmacol. 2004, 490:13-24.
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 13-24
-
-
McEwen, B.S.1
Reagan, L.P.2
|