LC-MS/MS method for simultaneous determination of viramidine and ribavirin levels in monkey red blood cells

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 3, 2007, Pages 1057-1064

  Yeh, Li Tain ^a   Nguyen, Mai ^a   Dadgostari, Sohelia ^a   Bu, Wei ^a   Lin, Chin Chung ^a  

^a Valeant Research and Development   (United States)

Author keywords

Hepatitis C; LC MS MS; Nucleoside; Nucleotide; Prodrug; Ribavirin; Viramidine

Indexed keywords

AMINOPROPYL; PERCHLORIC ACID; PROPANE; RIBAMIDINE; RIBAVIRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DILUTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; DRUG PURIFICATION; ELECTROSPRAY; ERYTHROCYTE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; QUALITY CONTROL; SOLID PHASE EXTRACTION; STANDARD;

ANIMALS; ANTIVIRAL AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTIDINE; ERYTHROCYTES; FEMALE; HAPLORHINI; MALE; MASS SPECTROMETRY; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; RIBAVIRIN;

EID: 33846614532     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.09.001     Document Type: Article

References (24)

1. Witkowski J.T., Robins R.K., Sidwell R.W., and Simon L.N. J. Med. Chem. 15 (1972) 1150-1154
2. Sidwell R.W., Huffman J.H., Khare G.P., Allen L.B., Witkowski J.T., and Robins R.K. Science 177 (1972) 705-706
3. Tam R.C., Lau J.Y., and Hong Z. Antiviral Chem. Chemother. 12 (2002) 260-272
4. Smee D.F., and Matthews T.R. Antimicrob. Agents Chemother. 30 (1986) 117-121
5. Zimmerman T.P., and Deeprose R.D. Biochem. Pharmacol. 27 (1978) 709-716
6. Page T., and Connor J.D. Int. J. Biochem. 22 (1990) 379-383
7. Glue P. Semin. Livers Dis. 19 (1999) 17-24
8. Wu J.Z., Walker H., Lau J.Y., and Hong Z. Antimicrob. Agents Chemother. 47 (2003) 426-431
9. Lin C., Yeh L.T., Vitarella D., and Hong Z. Antiviral Chem. Chemother. 14 (2003) 145-152
10. Lin C., Lourenco D., Xu G., and Yeh L.T. Antimicrob. Agents Chemother. 48 (2004) 1872-1875
11. Austin R.K., Trefts P.E., Hintz M., Connor J.D., and Kagnoff M.F. Antimicrob. Agents Chemother. 24 (1983) 696-701
12. Homma M., Jayewardene A.L., Gambertoglio J., and Aweeka F. Antimicrob. Agents Chemother. 43 (1999) 2716-2719
13. Lin C., Yeh L.T., and Lau J.Y. J. Chromatogr. B 779 (2002) 241-248
14. Yeh L.T., Nguyen M., Lourenco D., and Lin C.C. J. Pharm. Biomed. Anal. 38 (2005) 34-40
15. Yeh L.T., Nguyen M., and Lin C.C. J. Chromatogr. Sci. 41 (2003) 255-260
16. Shou W.Z., Bu H., Addison T., Jiang X., and Naidong W. J. Pharm. Biomed. Anal. 29 (2002) 83-94
17. Liu Y., Xu C., Yan R., Lim C., Yeh L.T., and Lin C. J. Chromatogr. B 832 (2006) 17-23
18. Moore J.D., Valette G., Darque A., Zhou X.J., and Sommadossi J.P. J. Am. Soc. Mass Spectrom. 11 (2000) 1134-1143
19. Rodriguez J.F., Rodriguez J.L., Santana J., Garcia H., and Rosario O. Antomicrob. Agents Chemother. 44 (2000) 3097-3100
20. Becher F., Pruvost A., Goujard C., Guerreiro C., Delfraissy J.F., Grassi J., and Benech H. Rapid Commun. Mass Spectrom. 16 (2002) 555-565
21. Becher F., Schlemmer D., Pruvost A., Nevers M.C., Goujard C., Jorajuria S., Guerreiro C., Brossette T., Lebeau L., Creminon C., Grassi J., and Benech H. Anal. Chem. 74 (2002) 4220-4227
22. Shi G., Wu J.T., Li Y., Geleziunas R., Gallagher K., Emm T., Olah T., and Unger S. Rapid Commun. Mass. Spectrom. 16 (2002) 1092-1099
23. Henneré G., Becher F., Pruvost A., Goujard C., Grassi J., and Benech H. J. Chromatogr. B 789 (2003) 273-281
24. Becher F., Pruvost A., Gale J., Couerbe P., Goujard C., Boutet V., Ezan E., Grassi J., and Benech H. J. Mass Spectrom. 38 (2003) 879-890