The cerebellum link to neuroticism: A volumetric MRI association study in healthy volunteers

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Schutter, Dennis J L G ^a,b   Koolschijn, P Cédric M P ^b   Peper, Jiska S ^b   Crone, Eveline A ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANXIETY; ARTICLE; BRAIN FUNCTION; BRAIN REGION; BRAIN SIZE; CEREBELLUM; CLINICAL ARTICLE; CORRELATIONAL STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; GRAY MATTER; HUMAN; IMAGE ANALYSIS; MALE; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NEUROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; RATING SCALE; REVISED NEO PERSONALITY INVENTORY; RIGHT HANDEDNESS; SCORING SYSTEM; VOLUMETRY; WHITE MATTER; ANXIETY DISORDER; BRAIN; HISTOLOGY; PATHOLOGY;

ANXIETY DISORDERS; BRAIN; CEREBELLUM; DEPRESSIVE DISORDER; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROTIC DISORDERS; YOUNG ADULT;

EID: 84861214468     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037252     Document Type: Article

References (34)

1. Snider RS, Maiti A, (1976) Cerebellar contributions to the Papez circuit. J Neurosci Res 2: 133-146.
2. Heath RG, Dempsey CW, Fontana CJ, Myers WA, (1978) Cerebellar stimulation Effects on septal region, hippocampus and amygdala of cats and rats. Biol Psychiatry 13: 501-529.
3. Schmahmann JD, Sherman JC, (1998) The cerebellar cognitive affective syndrome. Brain 121: 561-579.
4. Ivry RB, Spencer RM, (2004) The neural representation of time. Curr Opin Neurobiol 14: 225-232.
5. Zhu JN, Yung WH, Kwok-Chong Chow B, Chan YS, Wang JJ, (2006) The cerebellar hypothalamic circuits: Potential pathways underlying cerebellar involvement in somatic-visceral integration. Brain Res Rev 52: 93-106.
6. Schutter DJLG, Van Honk J, (2009) The cerebellum in emotion regulation: a repetitive transcranial magnetic stimulation study. Cerebellum 8: 28-34.
7. Shah SA, Doraiswamy PM, Husain MM, Escalona PR, Na C, et al. (1992) Posterior fossa abnormalities in major depression: A controlled magnetic resonance imaging study. Acta Psychiatr Scand 85: 474-479.
8. Escalona PR, MacDonald WM, Doraiswamy PM, Fiegel GS, Boyko OB, Ellinwood ER, et al. (1993) Reduction of cerebellar volume in major depression: A controlled MRI study. Depression 1: 156-158.
9. De Bellis MD, Kuchibhatla M, (2006) Cerebellar volumes in pediatric maltreatment related posttraumatic stress disorder. Biol Psychiatry 60: 697-703.
10. Pillay SS, Yurgelun-Todd DA, Bonello CM, Lafer B, Fava M, et al. (1997) A quantitative magnetic resonance imaging study of cerebral and cerebellar gray matter volume in primary unipolar major depression: Relationship to treatment response and clinical severity. Biol Psychiatry 42: 79-84.
11. Schutter DJLG, Van Honk J, (2005) The cerebellum on the rise in human emotion. Cerebellum 4: 290-294.
12. Baldaçara L, Jackowski AP, Schoedl A, Pupo M, Andreoli SB, et al. (2011) Reduced cerebellar left hemisphere and vermal volume in adults with PTSD from a community sample. J Psychiatr Res 45: 1627-1633.
13. Torvik A, Torp S, (1986) The prevalence of alcoholic cerebellar atrophy. A morphometric and histological study of an autopsy material. J Neurol Sci 75: 43-51.
14. Kühn S, Romanowski A, Schilling C, Mobascher A, Warbrick T, et al. (2012) Brain grey matter deficits in smokers: focus on the cerebellum. Brain Struct Funct 217: 517-522.
15. Van Haren NE, Koolschijn PC, Cahn W, Schnack HG, Hulshoff Pol HE, et al. (2010) Cigarette smoking and progressive brain volume loss in schizophrenia. Eur Neuropsychopharmacol 20: 454-458.
16. Costa PT, McCrae RR, (1992) Revised NEO Personality Inventory and NEO Five Factor Inventory Professional Manual Odessa, FL Psychological Assessment Resources.
17. Hoekstra HA, Ormel J, De Fruyt F, (1996) Handleiding NEO persoonlijkheidsvragenlijsten: NEO-PI-R en NEO-FFI Lisse Swets Test Services.
18. Kendler KS, Kuhn J, Prescott CA, (2004) The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression. Am J Psychiatry 161: 631-636.
19. Dale AM, Fischl B, Sereno MI, (1999) Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 9: 179-194.
20. Fischl B, Sereno MI, Dale AM, (1999) Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage 9: 195-207.
21. Fischl B, Dale AM, (2000) Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proc Natl Acad Sci U S A 97: 11050-11055.
22. Segonne F, Dale AM, Busa E, Glessner M, Salat D, et al. (2004) A hybrid approach to the skull stripping problem in MRI. Neuroimage 22: 1060-1075.
23. Fischl B, Salat DH, Busa E, Albert M, Dieterich M, et al. (2002) Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 33: 341-355.
24. Schraa-Tam CK, Rietdijk WJ, Verbeke WJ, Dietvorst RC, van den Berg WE, et al. (2012) fMRI activities in the emotional cerebellum: A preference for negative stimuli and goal-directed behavior. Cerebellum 11: 233-245.
25. Stoodley CJ, Schmahmann JD, (2010) Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing. Cortex 46: 831-844.
26. Baldaçara L, Nery-Fernandes F, Rocha M, Quarantini LC, Rocha GG, et al. (2011) Is cerebellar volume related to bipolar disorder? J Affect Disord 135: 305-309.
27. Yates WR, Jacoby CG, Andreasen NC, (1987) Cerebellar atrophy in schizophrenia and affective disorder. Am J Psychiatry 144: 465-467.
28. Buck R, (1999) The biological affects: a typology. Psychol Rev 106: 301-336.
29. Schmahmann JD, (2000) The role of the cerebellum in affect and psychosis. J Neurolinguistics 13: 189-214.
30. Ferrucci R, Giannicola G, Rosa M, Fumagalli M, Boggio PS, et al. (2011) Cerebellum and processing of negative facial emotions: Cerebellar transcranial DC stimulation specifically enhances the emotional recognition of facial anger and sadness. Cogn Emot DOI:10.1080/02699931.2011.619520.
31. Nater UM, Hoppmann C, Klumb P, (2010) Neuroticism and conscientiousness are associated with cortisol diurnal profiles in adults-role of positive and negative affect. Psychoneuroendocrinology 35: 1573-1577.
32. Pavlík A, Buresová M, (1984) The neonatal cerebellum: the highest level of glucocorticoid receptors in the brain. Brain Res 314: 13-20.
33. Karatsoreos IN, McEwen BS, (2011) Psychobiological allostasis: resistance, resilience and vulnerability. Trends Cogn Sci 15: 576-584.
34. Haines DE, Dietrichs E, (1984) An HRP study of hypothalamo-cerebellar and cerebello-hypothalamic connections in squirrel monkey (Saimiri scieureus). J Comp Neurol 229: 559-575.