-
1
-
-
48949093381
-
Steroidogenic enzymes
-
Miller, W. L. (2008) Steroidogenic enzymes. Endocr. Dev. 13, 1-18
-
(2008)
Endocr. Dev.
, vol.13
, pp. 1-18
-
-
Miller, W.L.1
-
2
-
-
77952800717
-
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones
-
Hu, J., Zhang, Z., Shen, W. J., and Azhar, S. (2010) Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. Nutr. Metab. 7, 47-73
-
(2010)
Nutr. Metab.
, vol.7
, pp. 47-73
-
-
Hu, J.1
Zhang, Z.2
Shen, W.J.3
Azhar, S.4
-
3
-
-
0018611739
-
Characterization of the lipoidal derivatives of pregnenolone prepared by incubation of the steroid with adrenal mitochondria
-
Mellon-Nussbaum, S., Ponticorvo, L., and Lieberman, S. (1979) Characterization of the lipoidal derivatives of pregnenolone prepared by incubation of the steroid with adrenal mitochondria. J. Biol. Chem. 254, 12500-12505 (Pubitemid 10138176)
-
(1979)
Journal of Biological Chemistry
, vol.254
, Issue.24
, pp. 12500-12505
-
-
Mellon-Nussbaum, S.1
Ponticorvo, L.2
Lieberman, S.3
-
4
-
-
0020399484
-
GLC/MS identification of new pregnenolone metabolites in confluent embryonic rat fibroblast cultures
-
DOI 10.1016/0022-4731(82)90034-6
-
Damon, M., and Chavis, C. (1982) GLC/MS identification of new pregnenolone metabolites in confluent embryonic rat fibroblast cultures. J. Steroid. Biochem. 16, 771-778 (Pubitemid 13228091)
-
(1982)
Journal of Steroid Biochemistry
, vol.16
, Issue.6
, pp. 771-778
-
-
Damon, M.1
Chavis, C.2
-
5
-
-
0025609473
-
Steroid fatty acid esters in adrenals and plasma: Effects of ACTH
-
Bélanger, B., Caron, S., Bélanger, A., and Dupont, A. (1990) Steroid fatty acid esters in adrenals and plasma: effects of ACTH. J. Endocrinol. 127, 505-511
-
(1990)
J. Endocrinol.
, vol.127
, pp. 505-511
-
-
Bélanger, B.1
Caron, S.2
Bélanger, A.3
Dupont, A.4
-
6
-
-
0030020791
-
Formation of pregnenolone- and dehydroepiandrosterone-fatty acid esters by lecithin-cholesterol acyltransferase in human plasma high density lipoproteins
-
Lavallée, B., Provost, P. R., and Belanger, A. (1996) Formation of pregnenolone- and dehydroepiandrosterone-fatty acid esters by lecithin-cholesterol acyltransferase in human plasma high density lipoproteins. Biochim. Biophys. Acta 1299, 306-312
-
(1996)
Biochim. Biophys. Acta
, vol.1299
, pp. 306-312
-
-
Lavallée, B.1
Provost, P.R.2
Belanger, A.3
-
7
-
-
67650032647
-
Acyl-coenzyme A:cholesterol acyltransferases
-
Chang, T. Y., Li, B. L., Chang, C. C., and Urano, Y. (2009) Acyl-coenzyme A:cholesterol acyltransferases. Am. J. Physiol. Endocrinol. Metab. 297, E1-E9
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Chang, T.Y.1
Li, B.L.2
Chang, C.C.3
Urano, Y.4
-
8
-
-
77649259094
-
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
-
Bryleva, E. Y., Rogers, M. A., Chang, C. C., Buen, F., Harris, B. T., Rousselet, E., Seidah, N. G., Oddo, S., LaFerla, F. M., Spencer, T. A., Hickey, W. F., and Chang, T. Y. (2010) ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proc. Natl. Acad. Sci. U.S.A. 107, 3081-3086
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 3081-3086
-
-
Bryleva, E.Y.1
Rogers, M.A.2
Chang, C.C.3
Buen, F.4
Harris, B.T.5
Rousselet, E.6
Seidah, N.G.7
Oddo, S.8
LaFerla, F.M.9
Spencer, T.A.10
Hickey, W.F.11
Chang, T.Y.12
-
9
-
-
27844475676
-
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain
-
DOI 10.1074/jbc.M508384200
-
Guo, Z. Y., Lin, S., Heinen, J. A., Chang, C. C., and Chang, T. Y. (2005) The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain. J. Biol. Chem. 280, 37814-37826 (Pubitemid 41642392)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.45
, pp. 37814-37826
-
-
Guo, Z.-Y.1
Lin, S.2
Heinen, J.A.3
Chang, C.C.Y.4
Chang, T.-Y.5
-
10
-
-
84861212469
-
Membrane bound O-acyltransferases (MBOAT)
-
Chang, C. C., Sun, J., and Chang, T. Y. (2011) Membrane bound O-acyltransferases (MBOAT). Front. Biol. 6, 177-182
-
(2011)
Front. Biol.
, vol.6
, pp. 177-182
-
-
Chang, C.C.1
Sun, J.2
Chang, T.Y.3
-
11
-
-
0038175518
-
Cholesterol is superior to 7-ketocholesterol or 7alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:Cholesterol acyltransferase 1
-
DOI 10.1074/jbc.M211559200
-
Zhang, Y., Yu, C., Liu, J., Spencer, T. A., Chang, C. C., and Chang, T. Y. (2003) Cholesterol is superior to 7-ketocholesterol or 7 alpha- hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1. J. Biol. Chem. 278, 11642-11647 (Pubitemid 36792726)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11642-11647
-
-
Zhang, Y.1
Yu, C.2
Liu, J.3
Spencer, T.A.4
Chang, C.C.Y.5
Chang, T.-Y.6
-
12
-
-
27444431715
-
Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: In vitro and intact cell studies
-
DOI 10.1042/BJ20050428
-
Liu, J., Chang, C. C., Westover, E. J., Covey, D. F., and Chang, T. Y. (2005) Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies. Biochem. J. 391, 389-397 (Pubitemid 41532437)
-
(2005)
Biochemical Journal
, vol.391
, Issue.2
, pp. 389-397
-
-
Liu, J.1
Chang, C.C.Y.2
Westover, E.J.3
Covey, D.F.4
Chang, T.-Y.5
-
13
-
-
0019051169
-
A method for the chemical synthesis of 14C-labeled fatty acyl coenzyme A's of high specific activity
-
Bishop, J. E., and Hajra, A. K. (1980) A method for the chemical synthesis of 14C-labeled fatty acyl coenzyme A's of high specific activity. Anal. Biochem. 106, 344-350
-
(1980)
Anal. Biochem.
, vol.106
, pp. 344-350
-
-
Bishop, J.E.1
Hajra, A.K.2
-
14
-
-
0034623070
-
Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine
-
Chang, C. C., Sakashita, N., Ornvold, K., Lee, O., Chang, E. T., Dong, R., Lin, S., Lee, C. Y., Strom, S. C., Kashyap, R., Fung, J. J., Farese, R. V., Jr., Patoiseau, J. F., Delhon, A., and Chang, T. Y. (2000) Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine. J. Biol. Chem. 275, 28083-28092
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28083-28092
-
-
Chang, C.C.1
Sakashita, N.2
Ornvold, K.3
Lee, O.4
Chang, E.T.5
Dong, R.6
Lin, S.7
Lee, C.Y.8
Strom, S.C.9
Kashyap, R.10
Fung, J.J.11
Farese Jr., R.V.12
Patoiseau, J.F.13
Delhon, A.14
Chang, T.Y.15
-
15
-
-
0033579429
-
Human acyl-CoA:cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro
-
Yu, C., Chen, J., Lin, S., Liu, J., Chang, C. C., and Chang, T. Y. (1999) Human acyl-CoA:cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro. J. Biol. Chem. 274, 36139-36145
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36139-36145
-
-
Yu, C.1
Chen, J.2
Lin, S.3
Liu, J.4
Chang, C.C.5
Chang, T.Y.6
-
16
-
-
78649278881
-
Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescence spectroscopy
-
Chang, C. C., Miyazaki, A., Dong, R., Kheirollah, A., Yu, C., Geng, Y., Higgs, H. N., and Chang, T. Y. (2010) Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescence spectroscopy. Biochemistry 49, 9957-9963
-
(2010)
Biochemistry
, vol.49
, pp. 9957-9963
-
-
Chang, C.C.1
Miyazaki, A.2
Dong, R.3
Kheirollah, A.4
Yu, C.5
Geng, Y.6
Higgs, H.N.7
Chang, T.Y.8
-
17
-
-
77957222802
-
Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice
-
Rousset, X., Vaisman, B., Auerbach, B., Krause, B. R., Homan, R., Stonik, J., Csako, G., Shamburek, R., and Remaley, A. T. (2010) Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice. J. Pharmacol. Exp. Ther. 335, 140-148
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.335
, pp. 140-148
-
-
Rousset, X.1
Vaisman, B.2
Auerbach, B.3
Krause, B.R.4
Homan, R.5
Stonik, J.6
Csako, G.7
Shamburek, R.8
Remaley, A.T.9
-
18
-
-
10044255546
-
Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain
-
DOI 10.1194/jlr.M400244-JLR200
-
Liere, P., Pianos, A., Eychenne, B., Cambourg, A., Liu, S., Griffiths, W., Schumacher, M., Sjövall, J., and Baulieu, E. E. (2004) Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain. J. Lipid Res. 45, 2287-2302 (Pubitemid 39602976)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.12
, pp. 2287-2302
-
-
Liere, P.1
Pianos, A.2
Eychenne, B.3
Cambourg, A.4
Liu, S.5
Griffiths, W.6
Schumacher, M.7
Sjovall, J.8
Baulieu, E.-E.9
-
19
-
-
33746615977
-
Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids
-
DOI 10.1373/clinchem.2006.068445
-
Kushnir, M. M., Rockwood, A. L., Roberts, W. L., Pattison, E. G., Owen, W. E., Bunker, A. M., and Meikle, A. W. (2006) Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids. Clin. Chem. 52, 1559-1567 (Pubitemid 44148319)
-
(2006)
Clinical Chemistry
, vol.52
, Issue.8
, pp. 1559-1567
-
-
Kushnir, M.M.1
Rockwood, A.L.2
Roberts, W.L.3
Pattison, E.G.4
Owen, W.E.5
Bunker, A.M.6
Meikle, A.W.7
-
20
-
-
12644304902
-
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: Evidence suggesting multiple cholesterol esterification enzymes in mammals
-
DOI 10.1073/pnas.93.24.14041
-
Meiner, V. L., Cases, S., Myers, H. M., Sande, E. R., Bellosta, S., Schambelan, M., Pitas, R. E., McGuire, J., Herz, J., and Farese, R. V., Jr. (1996) Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals. Proc. Natl. Acad. Sci. U.S.A. 93, 14041-14046 (Pubitemid 26424243)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.24
, pp. 14041-14046
-
-
Meiner, V.L.1
Cases, S.2
Myers, H.M.3
Sande, E.R.4
Bellosta, S.5
Schambelan, M.6
Pitas, R.E.7
Mcguire, J.8
Herzu, J.9
Farese Jr., R.V.10
-
22
-
-
0036133869
-
Neurosteroids: Biochemistry and clinical significance
-
DOI 10.1016/S1043-2760(01)00503-3, PII S1043276001005033
-
Mellon, S. H., and Griffin, L. D. (2002) Neurosteroids: biochemistry and clinical significance. Trends Endocrinol. Metab. 13, 35-43 (Pubitemid 36734014)
-
(2002)
Trends in Endocrinology and Metabolism
, vol.13
, Issue.1
, pp. 35-43
-
-
Mellon, S.H.1
Griffin, L.D.2
-
23
-
-
0028982924
-
Pregneolone-from Selye to Alzheimer and a model of the pregnenolone sulfate binding site on the GABAA receptor
-
Roberts, E. (1995) Pregneolone-from Selye to Alzheimer and a model of the pregnenolone sulfate binding site on the GABAA receptor. Biochem. Pharmacol. 49, 1-16
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 1-16
-
-
Roberts, E.1
-
24
-
-
0026588852
-
Δ5-3β-hydroxysteroid acyl transferase activity in the rat brain
-
Vourc'h, C., Eychenne, B., Jo, D. H., Raulin, J., Lapous, D., Baulieu, E. E., and Robel, P. (1992)Δ5-3β-hydroxysteroid acyl transferase activity in the rat brain. Steroids 57, 210-215
-
(1992)
Steroids
, vol.57
, pp. 210-215
-
-
Vourc'H, C.1
Eychenne, B.2
Jo, D.H.3
Raulin, J.4
Lapous, D.5
Baulieu, E.E.6
Robel, P.7
-
25
-
-
0037133501
-
Role of the N-terminal hydrophilic domain of acyl-coenzyme A:cholesterol acyltransferase 1 on the enzyme's quaternary structure and catalytic efficiency
-
DOI 10.1021/bi0120188
-
Yu, C., Zhang, Y., Lu, X., Chen, J., Chang, C. C., and Chang, T. Y. (2002) Role of the N-terminal hydrophilic domain of acyl-coenzyme A:cholesterol acyltransferase 1 on the enzyme's quaternary structure and catalytic efficiency. Biochemistry 41, 3762-3769 (Pubitemid 34224690)
-
(2002)
Biochemistry
, vol.41
, Issue.11
, pp. 3762-3769
-
-
Yu, C.1
Zhang, Y.2
Lu, X.3
Chen, J.4
Chang, C.C.Y.5
Chang, T.-Y.6
-
27
-
-
0037417922
-
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice
-
DOI 10.1073/pnas.0336398100
-
Willner, E. L., Tow, B., Buhman, K. K., Wilson, M., Sanan, D. A., Rudel, L. L., and Farese, R. V., Jr. (2003) Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 100, 1262-1267 (Pubitemid 36183990)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.3
, pp. 1262-1267
-
-
Willner, E.L.1
Tow, B.2
Buhman, K.K.3
Wilson, M.4
Sanan, D.A.5
Rudel, L.L.6
Farese Jr., R.V.7
|