Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 20, 2012, Pages 7923-7928

  Eltit, Jose Miguel ^a,b   Bannister, Roger A ^c   Moua, Ong ^c   Altamirano, Francisco ^d   Hopkins, Philip M ^e   Pessah, Isaac N ^f   Molinski, Tadeusz F ^g   López, Jose R ^a   Beam, Kurt G ^c   Allen, Paul D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CHILE   (Chile)

^e ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

IS; 1,4 Dihydropyridine receptor

Indexed keywords

CAFFEINE; CALCIUM CHANNEL L TYPE; RYANODINE RECEPTOR 1;

ANESTHESIA; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE MUTATION; IN VITRO STUDY; MALIGNANT HYPERTHERMIA; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SARCOPLASMIC RETICULUM; SENSITIVITY ANALYSIS; SKELETAL MUSCLE; WILD TYPE;

ANALYSIS OF VARIANCE; ANESTHETICS; BODY TEMPERATURE; CAFFEINE; CALCIUM; CAVEOLIN 1; DNA, COMPLEMENTARY; EXCITATION CONTRACTION COUPLING; FLUORESCENCE; GENES, DOMINANT; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALIGNANT HYPERTHERMIA; MICROELECTRODES; MUSCLE, SKELETAL; MUTATION, MISSENSE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 84861209384     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119207109     Document Type: Article

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