Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 17, 2011, Pages 7046-7051

  Eltit, José Miguel ^a,e   Li, Hongli ^a,f   Ward, Christopher W ^b   Molinski, Tadeusz ^c   Pessah, Isaac N ^d   Allen, Paul D ^a   Lopez, José R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF NURSING   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^f THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

L type calcium channel; Resting calcium

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; CALCIUM ION; RYANODINE RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CHANNEL GATING; CONFORMATION; DEPOLARIZATION; EXCITATION CONTRACTION COUPLING; MICROELECTRODE; MUSCLE CONTRACTION; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; HALOGENATED DIPHENYL ETHERS; ION CHANNEL GATING; MICE; MICE, MUTANT STRAINS; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOLEMMA;

EID: 79955566354     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018380108     Document Type: Article

References (36)

1. Perez CF, López JR, Allen PD (2005) Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle. Am J Physiol Cell Physiol 288:C640-C649. (Pubitemid 40229493)
2. Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: Dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4:517-529. (Pubitemid 36773404)
3. Turner PR, Westwood T, Regen CM, Steinhardt RA (1988) Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice. Nature 335:735-738.
4. Yang T, et al. (2007) Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol 292:C1591-C1598. (Pubitemid 47080573)
5. Lopez JR, Gerardi A, Lopez MJ, Allen PD (1992) Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia. Anesthesiology 76:711-719.
6. Moussa CE, et al. (2006) Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. FASEB J 20: 2165-2167.
7. Christensen RA, Shtifman A, Allen PD, Lopez JR, Querfurth HW (2004) Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes. J Biol Chem 279: 3524-53532.
8. Martonosi AN (1984) Mechanisms of Ca2+ release from sarcoplasmic reticulum of skeletal muscle. Physiol Rev 64:1240-1320.
9. Ríos E (2010) The cell boundary theorem: A simple law of the control of cytosolic calcium concentration. J Physiol Sci 60:81-84.
10. Eltit JM, et al. (2010) RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem 285:13781-13787.
11. Li H, et al. (2010) Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes. J Biol Chem 285:39171-39179.
12. Rios E (2010) RyR1 expression and the cell boundary theorem. J Biol Chem 285:le13; author reply le14.
13. Eltit JM, Perez C, Pessah IN, Allen PD, Lopez JR (2010) Reply to Rios: Cell boundary theorem and Ca2+ fluxes in skeletal muscle. J Biol Chem 285:le14.
14. Nakai J, et al. (1996) Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature 380:72-75. (Pubitemid 26076239)
15. Franzini-Armstrong C, Kish JW (1995) Alternate disposition of tetrads in peripheral couplings of skeletal muscle. J Muscle Res Cell Motil 16:319-324.
16. Takekura H, Bennett L, Tanabe T, Beam KG, Franzini-Armstrong C (1994) Restoration of junctional tetrads in dysgenic myotubes by dihydropyridine receptor cDNA. Biophys J 67:793-803. (Pubitemid 24235408)
17. Protasi F, Franzini-Armstrong C, Allen PD (1998) Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle. J Cell Biol 140:831-842. (Pubitemid 28141221)
18. Pessah IN, et al. (1997) Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol 272:C601-C614.
19. Mack MM, Molinski TF, Buck ED, Pessah IN (1994) Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J Biol Chem 269:23236-23249
20. Protasi F, Franzini-Armstrong C, Flucher BE (1997) Coordinated incorporation of skeletal muscle dihydropyridine receptors and ryanodine receptors in peripheral couplings of BC3H1 cells. J Cell Biol 137:859-870. (Pubitemid 27215508)
21. He LP, Hewavitharana T, Soboloff J, Spassova MA, Gill DL (2005) A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl) pyrazole derivative, BTP2. J Biol Chem 280:10997-11006. (Pubitemid 40418402)
22. Ward CW, et al. (2001) Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J 81:3216-3230. (Pubitemid 33111471)
23. Watras J, Katz AM (1984) Calcium release from two fractions of sarcoplasmic reticulum from rabbit skeletal muscle. Biochim Biophys Acta 769:429-439. (Pubitemid 14183702)
24. Tong J, McCarthy TV, MacLennan DH (1999) Measurement of resting cytosolic Ca2+ concentrations and Ca2+ store size in HEK-293 cells transfected with malignant hyperthermia or central core disease mutant Ca2+ release channels. J Biol Chem 274: 693-702.
25. Yang T, Ta TA, Pessah IN, Allen PD (2003) Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem 278:25722-25730. (Pubitemid 36835328)
26. Weiss RG, et al. (2004) Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. Am J Physiol Cell Physiol 287:C1094-C1102. (Pubitemid 39238334)
27. Pirone A, et al. (2010) Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the Cavalpha1S-subunit. Am J Physiol Cell Physiol 299:C1345-C1354.
28. Carpenter D, et al. (2009) The role of CACNA1S in predisposition to malignant hyperthermia. BMC Med Genet 10:104.
29. Zhou J, et al. (2006) A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle. Am J Physiol Cell Physiol 290:C539-C553.
30. Ward CW, et al. (2000) Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes. J Physiol 525:91-103. (Pubitemid 30311937)
31. Brandman O, Liou J, Park WS, Meyer T (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131:1327-1339. (Pubitemid 350297421)
32. López JR, Contreras J, Linares N, Allen PD (2000) Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ]. Anesthesiology 92:1799-1806. (Pubitemid 30412501)
33. Grabner M, Dirksen RT, Beam KG (1998) Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes. Proc Natl Acad Sci USA 95:1903-1908.
34. Westerman KA, Penvose A, Yang Z, Allen PD, Vacanti CA (2010) Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres. Exp Cell Res 316: 1966-1976.
35. Iribe G, et al. (2009) Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. Circ Res 104:787-795.
36. Lehnart SE, et al. (2008) Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest 118:2230-2245. (Pubitemid 351872341)