3′-Phosphoadenosine 5′-phosphosulfate (PAPS) synthases, naturally fragile enzymes specifically stabilized by nucleotide binding

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17645-17655

  Van Den Boom, Johannes ^a,b   Heider, Dominik ^a   Martin, Stephen R ^b   Pastore, Annalisa ^b   Mueller, Jonathan W ^a,b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIFUNCTIONAL; CAENORHABDITIS ELEGANS; CONTRIBUTING FACTOR; EXTRACELLULAR MATRICES; HUMAN PROTEINS; INTRINSIC TRYPTOPHAN FLUORESCENCES; MACHINE LEARNING TECHNIQUES; NATURAL LIGANDS; NATURALLY OCCURRING; NUCLEOTIDE BINDING; PHYSIOLOGICAL TEMPERATURE; PROTEIN MODIFICATIONS; PROTEIN STABILITY; RETROVIRAL INFECTIONS; SULFATION REACTION; SYNTHASE ENZYMES; SYNTHASES; THERMAL UNFOLDING; TIME-SCALES;

AMINO ACIDS; CIRCULAR DICHROISM SPECTROSCOPY; CLONING; ENZYMES; NUCLEOTIDES; PHYSIOLOGY;

PROTEINS;

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE SYNTHASE 1; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE SYNTHASE 2; ADENOSINE 5' PHOSPHOSULFATE; INSECT PROTEIN; MICROBIAL ENZYME; PPS 1 PROTEIN; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; MULTIENZYME COMPLEX; PAPS SYNTHETASE; SULFATE ADENYLYLTRANSFERASE;

ARTICLE; BINDING AFFINITY; CAENORHABDITIS ELEGANS; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME STABILITY; MOLECULAR CLONING; MOLECULAR MODEL; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN UNFOLDING; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT; ANIMAL; BINDING SITE; CHEMISTRY; HEAT; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN FOLDING;

CAENORHABDITIS ELEGANS; EUKARYOTA; INVERTEBRATA; METAZOA; NEMATODA;

ADENOSINE PHOSPHOSULFATE; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ENZYME STABILITY; HOT TEMPERATURE; HUMANS; MULTIENZYME COMPLEXES; PROTEIN BINDING; PROTEIN FOLDING; SULFATE ADENYLYLTRANSFERASE;

EID: 84861204831     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.325498     Document Type: Article

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