Insulin resistance and risk factors for cardiovascular disease in young adult survivors of childhood acute lymphoblastic leukemia

Journal of Clinical Oncology

Volumn 27, Issue 22, 2009, Pages 3698-3704

  Oeffinger, Kevin C ^a   Adams Huet, Beverley ^a   Victor, Ronald G ^a   Church, Timothy S ^a   Snell, Peter G ^a   Dunn, Andrea L ^a   Eshelman Kent, Debra A ^a   Ross, Robert ^a   Janiszewski, Peter M ^a   Turoff, Alicia J ^a   Brooks, Sandra ^a   Vega, Gloria Lena ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; C REACTIVE PROTEIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; ETOPOSIDE; GLUCOSE; INSULIN; LIPID; METHOTREXATE; PREDNISONE; VINCRISTINE; ANTINEOPLASTIC AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; BLOOD PRESSURE; CANCER RADIOTHERAPY; CANCER SURVIVOR; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; FEMALE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; SEX DIFFERENCE; CANCER STAGING; CHILD; CONFIDENCE INTERVAL; CROSS-SECTIONAL STUDY; DISEASE FREE SURVIVAL; FOLLOW UP; GLUCOSE BLOOD LEVEL; METHODOLOGY; MORTALITY; MULTIMODALITY CANCER THERAPY; ONSET AGE; PRESCHOOL CHILD; RADIATION EXPOSURE; RISK; RISK FACTOR; SKULL IRRADIATION; STATISTICS; SURVIVAL; SURVIVOR; TIME;

ADULT; AGE OF ONSET; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CONFIDENCE INTERVALS; CRANIAL IRRADIATION; CROSS-SECTIONAL STUDIES; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; INSULIN RESISTANCE; MALE; NEOPLASM STAGING; ODDS RATIO; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREVALENCE; RISK FACTORS; SURVIVAL ANALYSIS; SURVIVORS; TIME FACTORS; YOUNG ADULT;

EID: 68949110445     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2008.19.7251     Document Type: Article

References (55)

1. Geenen MM, Cardous-Ubbink MC, Kremer LC, et al: Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA 297:2705-2715, 2007
2. Mertens AC, Yasui Y, Neglia JP, et al: Late mortality experience in five-year survivors of childhood and adolescent cancer: The Childhood Cancer Survivor Study. J Clin Oncol 19:3163-3172, 2001
3. Pui CH, Cheng C, Leung W, et al: Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 349:640-649, 2003
4. Pui CH, Pei D, Sandlund JT, et al: Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia. J Clin Oncol 23:7936-7941, 2005
5. Oeffinger KC, Mertens AC, Sklar CA, et al: Chronic health conditions in adult survivors of childhood cancer. N Engl J Med 355:1572-1582, 2006
6. Ries LAG HD, Krapcho M, et al: SEER cancer statistics review, 1975-2003. Bethesda, MD, National Cancer Institute, 2006
7. Garmey EG, Liu Q, Sklar CA, et al: Longitudinal changes in obesity and body mass index among adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study. J Clin Oncol 26:4639-4645, 2008
8. Oeffinger KC, Mertens AC, Sklar CA, et al: Obesity in adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study. J Clin Oncol 21:1359-1365, 2003
9. Florin TA, Fryer GE, Miyoshi T, et al: Physical inactivity in adult survivors of childhood acute lymphoblastic leukemia: A report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev 16:1356-1363, 2007
10. Ness KK, Baker KS, Dengel DR, et al: Body composition, muscle strength deficits and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 49: 975-981, 2007
11. Gurney JG, Ness KK, Sibley SD, et al: Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia. Cancer 107:1303-1312, 2006
12. Kourti M, Tragiannidis A, Makedou A, et al: Metabolic syndrome in children and adolescents with acute lymphoblastic leukemia after the completion of chemotherapy. J Pediatr Hematol Oncol 27:499-501, 2005
13. Link K, Moell C, Garwicz S, et al: Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood. J Clin Endocrinol Metab 89:5003-5012, 2004
14. Oeffinger KC, Buchanan GR, Eshelman DA, et al: Cardiovascular risk factors in young adult survivors of childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol 23:424-430, 2001
15. Talvensaari KK, Lanning M, Tapanainen P, et al: Long-term survivors of childhood cancer have an increased risk of manifesting the metabolic syndrome. J Clin Endocrinol Metab 81:3051-3055, 1996
16. Janiszewski PM, Oeffinger KC, Church TS, et al: Abdominal obesity, liver fat and muscle composition in survivors of childhood acute lymphoblastic leukemia. J Clin Endocrinol Metab 92:3816-3821, 2007
17. Victor RG, Haley RW, Willett DL, et al: The Dallas Heart Study: A population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health. Am J Cardiol 93:1473-1480, 2004
18. Folsom AR, Jacobs DR Jr, Wagenknecht LE, et al: Increase in fasting insulin and glucose over seven years with increasing weight and inactivity of young adults: The CARDIA Study - Coronary Artery Risk Development in Young Adults. Am J Epidemiol 144:235-246, 1996
19. Bao W, Srinivasan SR, Berenson GS: Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults: The Bogalusa Heart Study. Circulation 93:54-59, 1996
20. Chen W, Srinivasan SR, Li S, et al: Clustering of long-term trends in metabolic syndrome variables from childhood to adulthood in Blacks and Whites: The Bogalusa Heart Study. Am J Epidemiol 166:527-533, 2007
21. Mattsson N, Ronnemaa T, Juonala M, et al: The prevalence of the metabolic syndrome in young adults: The Cardiovascular Risk in Young Finns Study. J Intern Med 261:159-169, 2007
22. Greenlund KJ, Kiefe CI, Gidding SS, et al: Differences in cardiovascular disease risk factors in black and white young adults: Comparisons among five communities of the CARDIA and the Bogalusa heart studies - Coronary Artery Risk Development In Young Adults. Ann Epidemiol 8:22-30, 1998
23. Diez Roux AV, Jacobs DR, Kiefe CI: Neighborhood characteristics and components of the insulin resistance syndrome in young adults: The coronary artery risk development in young adults (CARDIA) study. Diabetes Care 25:1976-1982, 2002
24. O'Brien E, Mee F, Atkins N, et al: Inaccuracy of seven popular sphygmomanometers for home measurement of blood pressure. J Hypertens 8:621-634, 1990
25. Khera A, de Lemos JA, Peshock RM, et al: Relationship between C-reactive protein and sub-clinical atherosclerosis: The Dallas Heart Study. Circulation 113:38-43, 2006
26. Vega GL, Adams-Huet B, Peshock R, et al: Influence of body fat content and distribution on variation in metabolic risk. J Clin Endocrinol Metab 91:4459-4466, 2006
27. Matthews DR, Hosker JP, Rudenski AS, et al: Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985
28. Grundy SM, Cleeman JI, Daniels SR, et al: Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112:2735-2752, 2005
29. Chen J, Wildman RP, Hamm LL, et al: Association between inflammation and insulin resistance in U.S. nondiabetic adults: Results from the Third National Health and Nutrition Examination Survey. Diabetes Care 27:2960-2965, 2004
30. Howard SC, Pui CH: Endocrine complications in pediatric patients with acute lymphoblastic leukemia. Blood Rev 16:225-243, 2002
31. Mohn A, Di Marzio A, Capanna R, et al: Persistence of impaired pancreatic beta-cell function in children treated for acute lymphoblastic leukaemia. Lancet 363:127-128, 2004
32. Mohn A, Di Marzio D, De Berardiniis A, et al: Long-term follow-up of children treated for acute lymphoblastic leukemia and the recovery of beta-cell function. Haematologica 91:1424-1425, 2006
33. Neville KA, Cohn RJ, Steinbeck KS, et al: Hyperinsulinemia, impaired glucose tolerance, and diabetes mellitus in survivors of childhood cancer: Prevalence and risk factors. J Clin Endocrinol Metab 91:4401-4407, 2006
34. Cook NR, Buring JE, Ridker PM: The effect of including C-reactive protein in cardiovascular risk prediction models for women. Ann Intern Med 145: 21-29, 2006
35. Ridker PM, Buring JE, Cook NR, et al: C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14 719 initially healthy American women. Circulation 107:391-397, 2003
36. Rutter MK, Meigs JB, Sullivan LM, et al: C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110:380-385, 2004
37. Tsimikas S, Willerson JT, Ridker PM: C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol 47:C19-31, 2006
38. Abdullah SM, Khera A, Leonard D, et al: Sex differences in the association between leptin and CRP: Results from the Dallas Heart Study. Atherosclerosis 195:404-410, 2007
39. Herder C, Schneitler S, Rathmann W, et al: Low-grade inflammation, obesity, and insulin resistance in adolescents. J Clin Endocrinol Metab 92: 4569-4574, 2007
40. Galassi A, Reynolds K, He J: Metabolic syndrome and risk of cardiovascular disease: A meta-analysis. Am J Med 119:812-819, 2006
41. Haffner SM: Risk constellations in patients with the metabolic syndrome: Epidemiology, diagnosis, and treatment patterns. Am J Med 119:S3-S9, 2006
42. Weiss R, Dziura J, Burgert TS, et al: Obesity and the metabolic syndrome in children and adolescents. N Engl J Med 350:2362-2374, 2004
43. Brennan BM, Rahim A, Blum WF, et al: Hyperleptinaemia in young adults following cranial irradiation in childhood: Growth hormone deficiency or leptin insensitivity? Clin Endocrinol (Oxf) 50:163-169, 1999
44. Ross JA, Oeffinger KC, Davies SM, et al: Genetic variation in the leptin receptor gene and obesity in survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study. J Clin Oncol 22:3558-3562, 2004
45. Armstrong GT, Sklar CA, Hudson MM, et al: Long-term health status among survivors of childhood cancer: Does sex matter? J Clin Oncol 25: 4477-4489, 2007
46. Chen W, Srinivasan SR, Berenson GS: Path analysis of metabolic syndrome components in black versus white children, adolescents, and adults: The Bogalusa Heart Study. Ann Epidemiol 18:85-91, 2008
47. Nguyen QM, Srinivasan SR, Xu JH, et al: Changes in risk variables of metabolic syndrome since childhood in prediabetic and type 2 diabetic subjects: The Bogalusa Heart Study. Diabetes Care 31:2044-2049, 2008
48. Ferrannini E, Mari A: How to measure insulin sensitivity. J Hypertens 16:895-906, 1998
49. Muniyappa R, Lee S, Chen H, et al: Current approaches for assessing insulin sensitivity and resistance in vivo: Advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab 294: E15-E26, 2008
50. Schwartz B, Jacobs DR Jr, Moran A, et al: Measurement of insulin sensitivity in children: Comparison between the euglycemic-hyperinsulinemic clamp and surrogate measures. Diabetes Care 31: 783-788, 2008
51. Bravata DM, Wells CK, Concato J, et al: Two measures of insulin sensitivity provided similar information in a U.S. population. J Clin Epidemiol 57: 1214-1217, 2004
52. Malita FM, Karelis AD, St-Pierre DH, et al: Surrogate indexes vs. euglycaemic-hyperinsulinemic clamp as an indicator of insulin resistance and cardiovascular risk factors in overweight and obese postmenopausal women. Diabetes Metab 32:251-255, 2006
53. Song Y, Manson JE, Tinker L, et al: Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: The Women's Health Initiative Observational Study. Diabetes Care 30:1747-1752, 2007
54. Wallace TM, Levy JC, Matthews DR: Use and abuse of HOMA modeling. Diabetes Care 27:1487-1495, 2004
55. Wallace TM, Matthews DR: The assessment of insulin resistance in man. Diabet Med 19:527-534, 2002