The effects of levosimendan vs dobutamine added to dopamine on liver functions assessed with noninvasive liver function monitoring in patients with septic shock

Journal of Critical Care

Volumn 27, Issue 3, 2012, Pages 318.e1-318.e6

  Memiş, Dilek ^a   Inal, Mehmet Turan ^a   Sut, Necdet ^a  

^a TRAKYA UNIVERSITY   (Turkey)

Author keywords

Dobutamine; Indocyanine green; Levosimendan; Plasma disappearance rate; Septic shock

Indexed keywords

DOBUTAMINE; DOPAMINE; INDOCYANINE GREEN; LEVOSIMENDAN;

ADULT; ARTERY PERFUSION; ARTICLE; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; FEMALE; HEART HEMODYNAMICS; HUMAN; INTENSIVE CARE UNIT; LIVER FUNCTION; LIVER FUNCTION MONITORING; MALE; MEAN ARTERIAL PRESSURE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEPTIC SHOCK; SYSTEMIC CIRCULATION; SYSTOLIC BLOOD PRESSURE;

EID: 84861199740     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2011.06.008     Document Type: Article

References (35)

1. Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 29:1303-1310.
2. Brun-Buisson C. The epidemiology of the systemic inflammatory response. Intensive Care Med 2000, 26:64-74.
3. Pinto B.B., Rehberg S., Ertmer C., Westphal M. Role of levosimendan in sepsis and septic shock. Curr Opin Anaesthesiol 2008, 21:168-177.
4. Fries M., Ince C., Rossaint R., Bleilevens C., Bickenbach J., Rex S., et al. Levosimendan but not norepinephrine improves microvascular oxygenation during experimental septic shock. Crit Care Med 2008, 36:1886-1891.
5. Dubin A., Maskin B., Murias G., Pozo M.O., Sottile J.P., Barán M., et al. Effects of levosimendan in normodynamic endotoxaemia: a controlled experimental study. Resuscitation 2006, 69:277-286.
6. Parrillo J.E. Pathogenetic mechanisms of septic shock. N Engl J Med 1993, 328:1471-1477.
7. Task Force of the American College of Critical Care Medicine, Society of Critical Care Practice parameters for hemodynamic support of sepsis in adult patients in sepsis. Crit Care Med 1999, 27:639-660.
8. Fiddian-Green R.G., Haglund U., Gutierrez G., Shoemaker W.C. Goals for the resuscitation of shock. Crit Care Med 1993, 21:25-31.
9. Hiltebrand L.B., Krejci V., Sigurdsson G.H. Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia. Anesthesiology 2004, 100:1188-1197.
10. Martikainen T.J., Uusaro A., Tenhunen J.J., Ruokonen E. Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock. Acta Anaesthesiol Scand 2004, 48:935-943.
11. Boyd O., Lamb G., Mackay C.J., Grounds R.M., Bennett E.D. A comparison of the efficacy of dopexamine and dobutamine for increasing oxygen delivery in high-risk surgical patients. Anaesth Intensive Care 1995, 23:478-484.
12. Webb A.R., Moss R.F., Tighe D., Al-Saady N., Bennett E.D. The effects of dobutamine, dopexamine and fluid on hepatic histological responses to porcine faecal peritonitis. Intensive Care Med 1991, 17:487-493.
13. Priebe H.J., Nöldge G.F., Armbruster K., Geiger K. Differential effects of dobutamine, dopamine, and noradrenaline on splanchnic haemodynamics and oxygenation in the pig. Acta Anaesthesiol Scand 1995, 39:1088-1096.
14. Heino A., Hartikainen J., Merasto M.E., Koski E.M., Tenhunen J., Alhava E., et al. Effects of dobutamine on splanchnic tissue perfusion during partial superior mesenteric artery occlusion. Crit Care Med 2000, 28:3484-3490.
15. Oldner A., Konrad D., Weitzberg E., Rudehill A., Rossi P., Wanecek M. Effects of levosimendan, a novel inotropic calcium sensitizing drug, in experimental septic shock. Crit Care Med 2001, 29:2185-2193.
16. Morelli A., De Castro S., Teboul J.L., Singer M., Rocco M., Conti G., et al. Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive Care Med 2005, 31:638-644.
17. Faybik P., Krenn C.G., Baker A., Lahner D., Berlakovich G., Steltzer H., et al. Comparison of invasive and noninvasive measurement of plasma disappearance rate of indocyanine green in patients undergoing liver transplantation: a prospective investigator-blinded study. Liver Transpl 2004, 10:1060-1064.
18. Sakka S.G., Reinhart K., Meier-Hellmann A. Comparison of invasive and noninvasive measurements of indocyanine green plasma disappearance rate in critically ill patients with mechanical ventilation and stable hemodynamics. Intensive Care Med 2000, 26:1553-1557.
19. Sakka S.G., Reinhart K., Meier-Hellmann A. Prognostic value of the indocyanine green plasma disappearance rate in critically ill patients. Chest 2002, 122(5):1715-1720.
20. Bone R.C., Balk R.A., Cerra F.B., Dellinger R.P., Fein A.M., Knaus W.A., et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992, 101:1644-1655.
21. Bellomo R., Ronco C., Kellum J.A., Mehta R.L., Palevsky P. Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Critical Care 2004, 8:204-212.
22. Inal M.T., Memiş D., Kargi M., Sut N. Prognostic value of indocyanine green elimination assessed with LiMON in septic patients. J Crit Care 2009, 24:329-334.
23. Ueno S., Tanabe G., Yamada H., Kusano C., Yoshidome S., Nuruki K., et al. Response of patients with cirrhosis who have undergone partial hepatectomy to treatment aimed at achieving supranormal oxygen delivery and consumption. Surgery 1998, 123:278-286.
24. Kimura S., Yoshioka T., Shibuya M., Sakano T., Tanaka R., Matsuyama S. Indocyanine green elimination rate detects hepatocellular dysfunction early in septic shock and correlates with survival. Crit Care Med 2001, 29:1159-1163.
25. Follath F., Cleland J.G., Just H., Papp J.G., Scholz H., Peuhkurinen K., et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet 2002, 360:196-202.
26. Nanas J.N., Papazoglou P.P., Terrovitis J.V., Kanakakis J., Dalianis A., Tsolakis E., et al. Hemodynamic effects of levosimendan added to dobutamine in patients with decompensated advanced heart failure refractory to dobutamine alone. Am J Cardiol 2004, 94:1329-1332.
27. Nieminen M.S., Akkila J., Hasenfuss G., Kleber F.X., Lehtonen L.A., Mitrovic V., et al. Hemodynamic and neurohumoral effects of continuous infusion of levosimendan in patients with congestive heart failure. J Am Coll Cardiol 2000, 36:1903-1912.
28. Barraud D., Faivre V., Damy T., Welschbillig S., Gayat E., Heymes C., et al. Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: comparison with dobutamine and milrinone. Crit Care Med 2007, 35:1376-1382.
29. Morelli A., Teboul J.L., Maggiore S.M., Vieillard-Baron A., Rocco M., Conti G., et al. Effects of levosimendan on right ventricular afterload in patients with acute respiratory distress syndrome: a pilot study. Crit Care Med 2006, 34:2287-2293.
30. Regnier B., Safran D., Carlet J., Teisseire B. Comparative haemodynamic effects of dopamine and dobutamine in septic shock. Intensive Care Med 1979, 5:115-120.
31. Tell B., Majerus T.C., Flancbaum L. Dobutamine in elderly septic shock patients refractory to dopamine. Intensive Care Med 1987, 13:14-18.
32. Uusaro A., Ruokonen E., Takala J. Splanchnic oxygen transport after cardiac surgery: evidence for inadequate tissue perfusion after stabilization of hemodynamics. Intensive Care Med 1996, 22:26-33.
33. Joly L.M., Monchi M., Cariou A., Chiche J.D., Bellenfant F., Brunet F., et al. Effects of dobutamine on gastric mucosal perfusion and hepatic metabolism in patients with septic shock. Am J Resp Crit Care Med 1999, 160:1983-1986.
34. Creteur J., De Backer D., Vincent J.L. A dobutamine test can disclose hepatosplanchnic hypoperfusion in septic patients. Am J Resp Crit Care Med 1999, 160:839-845.
35. 2 gradient in abdominal aortic aneurysm surgery. Acta Anaesthesiol Scand 2008, 52:785-792.