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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 11, 2012, Pages 3837-3841

Synthesis and biological activity of carbamate-linked cationic lipids for gene delivery in vitro

(9) Zhi, Defu a,b Zhang, Shubiao b Qureshi, Farooq c Zhao, Yinan b Cui, Shaohui b Wang, Bing b Chen, Huiying b Wang, Yinhuan d Zhao, Defeng a

a DALIAN UNIVERSITY OF TECHNOLOGY (China)

b DALIAN NATIONALITIES UNIVERSITY (China)

c Pharmaceutical and Analytical R and D (United States)

d Dalian Trico Chemical Co Ltd (China)

Author keywords

Carbamate linked cationic lipids; Cytotoxicity; DNA condensation; Gene delivery; Transfection efficiency

Indexed keywords

CARBAMIC ACID; CATION; HYDROCARBON; LIPID; LIPOFECTAMINE; LIPOSOME; N 1 2,3 DIDODECYL CARBAMOYLOXY PROPYL N ETHYL N,N DIMETHYLAMMONIUM IODIDE; N 1 2,3 DIDODECYLCARBAMOYLOXY PROPYL N,N,N TRIMETHYLAMMONIUM IODIDE; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DNA BINDING; GENE TARGETING; GENETIC TRANSFECTION; HELA CELL; HEP 2 CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; SYNTHESIS; ZETA POTENTIAL;

APOPTOSIS; CARBAMATES; CATIONS; ELECTROPHORESIS, AGAR GEL; HELA CELLS; HEP G2 CELLS; HUMANS; LIPOSOMES; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; TRANSFECTION;

EID: 84861197074 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.01.097 Document Type: Article

Times cited : (36)

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