Positive allosteric modulation of α4β2 nAChR agonist induced behaviour

Brain Research

Volumn 1458, Issue , 2012, Pages 67-75

  Rode, F ^a   Munro, G ^a   Holst, D ^a   Nielsen, E O ^a   Troelsen, K B ^a   Timmermann, D B ^a   Ronn, L C B ^a   Grunnet, M ^a  

^a NEUROSEARCH A S   (Denmark)

Author keywords

4 2 nAChR; 6 OHDA model; Acute pain; Partial agonist; Positive allosteric modulation; Striatal dopamine release

Indexed keywords

ANALGESIC AGENT; MECAMYLAMINE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR ALPHA4BETA2; NOMIFENSINE; NS 3956; NS 9283; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DOPAMINE RELEASE; FEMALE; IN VITRO STUDY; LOW DRUG DOSE; MALE; NONHUMAN; PAIN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; STOICHIOMETRY;

ALLOSTERIC REGULATION; ANIMALS; AZEPINES; CORPUS STRIATUM; FEMALE; MALE; NICOTINIC AGONISTS; OXADIAZOLES; OXIDOPAMINE; PAIN; PAIN MEASUREMENT; PARKINSONIAN DISORDERS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, NICOTINIC; ROTATION;

ANIMALIA; RATTUS;

EID: 84861197048     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.03.064     Document Type: Article

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