Overexpression of mouse angiotensinogen in renal proximal tubule causes salt-sensitive hypertension in mice

American Journal of Hypertension

Volumn 25, Issue 6, 2012, Pages 684-689

  Ying, Jian ^a   Stuart, Deborah ^a   Hillas, Elaine ^a   Gociman, Barbu R ^a   Ramkumar, Nirupama ^a   Lalouel, Jean Marc ^a   Kohan, Donald E ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

Angiotensinogen; blood pressure; hypertension; kidney; proximal tubule; renin; transgene

Indexed keywords

ANGIOTENSIN II; ANGIOTENSINOGEN; COMPLEMENTARY DNA; KIDNEY ANDROGEN PROTEIN; MESSENGER RNA; POTASSIUM ION; PROTEIN; RENIN; SODIUM CHLORIDE; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; GENE OVEREXPRESSION; HYPERTENSION; IN SITU HYBRIDIZATION; INTERNAL RIBOSOME ENTRY SITE; KIDNEY; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALT SENSITIVE HYPERTENSION; SODIUM INTAKE; SYSTOLIC BLOOD PRESSURE; TELEMETRY; TRANSGENE; URINARY EXCRETION; URINE LEVEL;

ANGIOTENSINOGEN; ANIMALS; BLOOD PRESSURE; CHIMERA; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCK-IN TECHNIQUES; HYPERTENSION; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED C57BL; RENIN; RENIN-ANGIOTENSIN SYSTEM; RNA, MESSENGER; SODIUM CHLORIDE, DIETARY;

EID: 84861191190     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2012.16     Document Type: Article

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