-
1
-
-
71049154453
-
Third consensus on medical treatment of metastatic breast cancer
-
S. Beslija, J. Bonneterre, H.J. Burstein Third consensus on medical treatment of metastatic breast cancer Ann Oncol 20 2009 1771 1785
-
(2009)
Ann Oncol
, vol.20
, pp. 1771-1785
-
-
Beslija, S.1
Bonneterre, J.2
Burstein, H.J.3
-
3
-
-
68449084678
-
Metastatic breast cancer: Therapeutic options according to molecular subtypes and prior adjuvant therapy
-
V. Guarneri, P. Conte Metastatic breast cancer: therapeutic options according to molecular subtypes and prior adjuvant therapy Oncologist 14 2009 645 656
-
(2009)
Oncologist
, vol.14
, pp. 645-656
-
-
Guarneri, V.1
Conte, P.2
-
5
-
-
0029038721
-
The prognostic value of c-erbB2 in primary breast carcinomas: A study on 942 cases
-
N. Quénel, J. Wafflart, F. Bonichon The prognostic value of c-erbB2 in primary breast carcinomas: a study on 942 cases Breast Cancer Res Treat 35 1995 283 291
-
(1995)
Breast Cancer Res Treat
, vol.35
, pp. 283-291
-
-
Quénel, N.1
Wafflart, J.2
Bonichon, F.3
-
6
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
D.J. Slamon, B. Leyland-Jones, S. Shak Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N Engl J Med 344 2001 783 792
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
7
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group
-
M. Marty, F. Cognetti, D. Maraninchi Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group J Clin Oncol 23 2005 4265 4274
-
(2005)
J Clin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
-
8
-
-
43449119572
-
Superior long-term survival benefits of trastuzumab plus docetaxel compared to docetaxel alone in patients with HER2-positive metastatic breast cancer: Patients surviving more than 4 years in the M77001 study
-
abstract 2067
-
M. Marty, F. Cognetti, D. Maraninchi Superior long-term survival benefits of trastuzumab plus docetaxel compared to docetaxel alone in patients with HER2-positive metastatic breast cancer: patients surviving more than 4 years in the M77001 study Breast Cancer Res Treat 100 suppl 1 2006 abstract 2067
-
(2006)
Breast Cancer Res Treat
, vol.100
, Issue.SUPPL. 1
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
-
9
-
-
79951974161
-
Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: The HERNATA study
-
M. Andersson, E. Lidbrink, K. Bjerre Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: the HERNATA study J Clin Oncol 29 2011 264 271
-
(2011)
J Clin Oncol
, vol.29
, pp. 264-271
-
-
Andersson, M.1
Lidbrink, E.2
Bjerre, K.3
-
10
-
-
33745530224
-
Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer
-
N. Robert, B. Leyland-Jones, L. Asmar Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer J Clin Oncol 24 2006 2786 2792
-
(2006)
J Clin Oncol
, vol.24
, pp. 2786-2792
-
-
Robert, N.1
Leyland-Jones, B.2
Asmar, L.3
-
11
-
-
79951982754
-
Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): Two highly active therapeutic regimens
-
V. Valero, J. Forbes, M.D. Pegram Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens J Clin Oncol 29 2011 149 156
-
(2011)
J Clin Oncol
, vol.29
, pp. 149-156
-
-
Valero, V.1
Forbes, J.2
Pegram, M.D.3
-
12
-
-
74849122823
-
A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: An Eastern Cooperative Oncology Group trial
-
S. Moulder, H. Li, M. Wang A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: an Eastern Cooperative Oncology Group trial Breast Cancer Res Treat 119 2010 663 671
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 663-671
-
-
Moulder, S.1
Li, H.2
Wang, M.3
-
13
-
-
70350596106
-
The role of HER2-targeted therapies in women with HER2-overexpressing metastatic breast cancer
-
S. Dent, S.H. Verma, J. Latreille The role of HER2-targeted therapies in women with HER2-overexpressing metastatic breast cancer Curr Oncol 16 2009 25 35
-
(2009)
Curr Oncol
, vol.16
, pp. 25-35
-
-
Dent, S.1
Verma, S.H.2
Latreille, J.3
-
14
-
-
57649236271
-
Efficacy and safety of trastuzumab plus vinorelbine as second-line treatment for women with HER2-positive metastatic breast cancer beyond disease progression
-
abstract 1094 Accessed: March 28, 2012
-
T. Bachelot, L. Mauriac, C. Delcambre Efficacy and safety of trastuzumab plus vinorelbine as second-line treatment for women with HER2-positive metastatic breast cancer beyond disease progression J Clin Oncol 25 suppl 2007 abstract 1094 www.asco.org Accessed: March 28, 2012
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Bachelot, T.1
Mauriac, L.2
Delcambre, C.3
-
15
-
-
34548543191
-
Capecitabine and trastuzumab in heavily pretreated metastatic breast cancer
-
R. Bartsch, C. Wenzel, G. Altorjai Capecitabine and trastuzumab in heavily pretreated metastatic breast cancer J Clin Oncol 25 2007 3853 3858
-
(2007)
J Clin Oncol
, vol.25
, pp. 3853-3858
-
-
Bartsch, R.1
Wenzel, C.2
Altorjai, G.3
-
16
-
-
70350610174
-
Trastuzumab-containing therapies: Activity beyond disease progression in M.B.C. - A pivotal experience
-
abstract 10788
-
S. Del Bianco, R. Rondinelli Trastuzumab-containing therapies: activity beyond disease progression in M.B.C. - a pivotal experience J Clin Oncol 24 suppl 2006 abstract 10788
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Del Bianco, S.1
Rondinelli, R.2
-
17
-
-
33749416983
-
Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer
-
L. Orlando, A. Cardillo, R. Ghisini Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer BMC Cancer 6 2006 225 233
-
(2006)
BMC Cancer
, vol.6
, pp. 225-233
-
-
Orlando, L.1
Cardillo, A.2
Ghisini, R.3
-
18
-
-
33748557778
-
Trastuzumab in combination with gemcitabine and vinorelbine as second-line therapy for HER-2/neu overexpressing metastatic breast cancer
-
A. Morabito, R. Longo, D. Gattuso Trastuzumab in combination with gemcitabine and vinorelbine as second-line therapy for HER-2/neu overexpressing metastatic breast cancer Oncol Rep 16 2006 393 398
-
(2006)
Oncol Rep
, vol.16
, pp. 393-398
-
-
Morabito, A.1
Longo, R.2
Gattuso, D.3
-
19
-
-
1842614245
-
Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression
-
D. Tripathy, D.J. Slamon, M. Cobleigh Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression J Clin Oncol 22 2004 1063 1070
-
(2004)
J Clin Oncol
, vol.22
, pp. 1063-1070
-
-
Tripathy, D.1
Slamon, D.J.2
Cobleigh, M.3
-
20
-
-
77956793546
-
Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: The observational Hermine study
-
J.M. Extra, E.C. Antoine, A. Vincent-Salomon Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: the observational Hermine study Oncologist 15 2010 799 809
-
(2010)
Oncologist
, vol.15
, pp. 799-809
-
-
Extra, J.M.1
Antoine, E.C.2
Vincent-Salomon, A.3
-
21
-
-
65849322821
-
Continuing trastuzumab beyond disease progression: Outcomes analysis in patients with metastatic breast cancer
-
G. Cancello, E. Montagna, D. D'Agostino Continuing trastuzumab beyond disease progression: outcomes analysis in patients with metastatic breast cancer Breast Cancer Res 10 2008 R60
-
(2008)
Breast Cancer Res
, vol.10
, pp. 60
-
-
Cancello, G.1
Montagna, E.2
D'Agostino, D.3
-
22
-
-
65349110371
-
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A german breast group 26/breast international group 03-05 study
-
G. von Minckwitz, A. du Bois, M. Schmidt Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study J Clin Oncol 27 2009 1999 2006
-
(2009)
J Clin Oncol
, vol.27
, pp. 1999-2006
-
-
Von Minckwitz, G.1
Du Bois, A.2
Schmidt, M.3
-
23
-
-
42049121934
-
Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: Molecular mechanism and clinical implications for endocrine therapy resistance
-
G. Arpino, L. Wiechmann, C.K. Osborne Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance Endocr Rev 29 2008 217 233
-
(2008)
Endocr Rev
, vol.29
, pp. 217-233
-
-
Arpino, G.1
Wiechmann, L.2
Osborne, C.K.3
-
24
-
-
71949087792
-
Lapatinib plus letrozole for postmenopausal patients with advanced HER2(+)/HR(+) breast cancer
-
V. Guarneri Lapatinib plus letrozole for postmenopausal patients with advanced HER2(+)/HR(+) breast cancer Expert Rev Anticancer Ther 9 2009 1549 1557
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, pp. 1549-1557
-
-
Guarneri, V.1
-
25
-
-
0037420192
-
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer
-
C.K. Osborne, V. Bardou, T.A. Hopp Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer J Natl Cancer Inst 95 2003 353 361
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 353-361
-
-
Osborne, C.K.1
Bardou, V.2
Hopp, T.A.3
-
26
-
-
27644597480
-
A meta-analysis on the interaction between HER-2 expression and response to endocrine treatment in advanced breast cancer
-
M. De Laurentiis, G. Arpino, E. Massarelli A meta-analysis on the interaction between HER-2 expression and response to endocrine treatment in advanced breast cancer Clin Cancer Res 11 2005 4741 4748
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4741-4748
-
-
De Laurentiis, M.1
Arpino, G.2
Massarelli, E.3
-
27
-
-
83855160939
-
Hormone-receptor expression and activity of trastuzumab with chemotherapy in HER2-positive advanced breast cancer patients
-
F. Montemurro, V. Rossi, M. Cossu Rocca Hormone-receptor expression and activity of trastuzumab with chemotherapy in HER2-positive advanced breast cancer patients Cancer 118 2012 17 26
-
(2012)
Cancer
, vol.118
, pp. 17-26
-
-
Montemurro, F.1
Rossi, V.2
Cossu Rocca, M.3
-
28
-
-
73949105921
-
Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor+ metastatic breast cancer: Results from the randomized phase III TAnDEM study
-
B. Kaufman, J.R. Mackey, M.R. Clemens Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor+ metastatic breast cancer: results from the randomized phase III TAnDEM study J Clin Oncol 27 2009 5529 5537
-
(2009)
J Clin Oncol
, vol.27
, pp. 5529-5537
-
-
Kaufman, B.1
MacKey, J.R.2
Clemens, M.R.3
-
29
-
-
4644289313
-
A unique structure for epidermal growth factor receptor bound to GW572016 (lapatinib): Relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells
-
E.R. Wood, A.T. Truesdale, O.B. McDonald A unique structure for epidermal growth factor receptor bound to GW572016 (lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells Cancer Res 64 2004 6652 6659
-
(2004)
Cancer Res
, vol.64
, pp. 6652-6659
-
-
Wood, E.R.1
Truesdale, A.T.2
McDonald, O.B.3
-
30
-
-
44849108294
-
A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer
-
H.J. Burstein, A.M. Storniolo, S. Franco A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer Ann Oncol 19 2008 1068 1074
-
(2008)
Ann Oncol
, vol.19
, pp. 1068-1074
-
-
Burstein, H.J.1
Storniolo, A.M.2
Franco, S.3
-
31
-
-
46449113024
-
Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer
-
H.L. Gomez, D.C. Doval, M.A. Chavez Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer J Clin Oncol 26 2008 2999 3005
-
(2008)
J Clin Oncol
, vol.26
, pp. 2999-3005
-
-
Gomez, H.L.1
Doval, D.C.2
Chavez, M.A.3
-
32
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
C.E. Geyer, J. Foster, D. Lindquist Lapatinib plus capecitabine for HER2-positive advanced breast cancer N Engl J Med 356 2006 2733 2743
-
(2006)
N Engl J Med
, vol.356
, pp. 2733-2743
-
-
Geyer, C.E.1
Foster, J.2
Lindquist, D.3
-
33
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
D. Cameron, M. Casey, M. Press A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses Breast Cancer Res Treat 112 2008 533 543
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 533-543
-
-
Cameron, D.1
Casey, M.2
Press, M.3
-
34
-
-
73149115341
-
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor+ metastatic breast cancer
-
S. Johnston, J. Pippen Jr, X. Pivot Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor+ metastatic breast cancer J Clin Oncol 27 2009 5538 5546
-
(2009)
J Clin Oncol
, vol.27
, pp. 5538-5546
-
-
Johnston, S.1
Pippen, Jr.J.2
Pivot, X.3
-
35
-
-
40449112910
-
Letrozole versus letrozole plus lapatinib (GW572016) in hormone-sensitive, HER2-negative operable breast cancer: A double-blind, randomized, phase II study with biomarker evaluation (EGF109077-LAP107692/ LETLOB)
-
A. Frassoldati, V. Guarneri, F. Piacentini Letrozole versus letrozole plus lapatinib (GW572016) in hormone-sensitive, HER2-negative operable breast cancer: a double-blind, randomized, phase II study with biomarker evaluation (EGF109077-LAP107692/LETLOB) Clin Breast Cancer 8 2008 97 100
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 97-100
-
-
Frassoldati, A.1
Guarneri, V.2
Piacentini, F.3
-
36
-
-
84855404334
-
TBCRC 003: Phase II trial of trastuzumab (T) and lapatinib (L) in patients (pts) with HER2+ metastatic breast cancer (MBC)
-
abstract 527 Accessed: March 28, 2012
-
N.U. Lin, I.A. Mayer, N.S. Najita TBCRC 003: phase II trial of trastuzumab (T) and lapatinib (L) in patients (pts) with HER2+ metastatic breast cancer (MBC) J Clin Oncol 29 suppl 2011 abstract 527 www.asco.org Accessed: March 28, 2012
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Lin, N.U.1
Mayer, I.A.2
Najita, N.S.3
-
37
-
-
77949884661
-
Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
-
K.L. Blackwell, H.J. Burstein, A.M. Storniolo Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer J Clin Oncol 28 2010 1124 1130
-
(2010)
J Clin Oncol
, vol.28
, pp. 1124-1130
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
38
-
-
77949721591
-
Updated survival analysis of a randomized study of lapatinib alone or in combination with trastuzumab in women with HER2-positive metastatic breast cancer progressing on trastuzumab therapy
-
abstract 61
-
K.L. Blackwell, H.L. Burstein, G.W. Sledge Updated survival analysis of a randomized study of lapatinib alone or in combination with trastuzumab in women with HER2-positive metastatic breast cancer progressing on trastuzumab therapy Cancer Res (San Antonio Breast Cancer Symposium) 69 2009 abstract 61
-
(2009)
Cancer Res (San Antonio Breast Cancer Symposium)
, vol.69
-
-
Blackwell, K.L.1
Burstein, H.L.2
Sledge, G.W.3
-
39
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
K. Miller, M. Wang, J. Gralow Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer N Engl J Med 357 2007 2666 2676
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
40
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
D.W. Miles, A. Chan, L.Y. Dirix Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer J Clin Oncol 28 2010 3239 3247
-
(2010)
J Clin Oncol
, vol.28
, pp. 3239-3247
-
-
Miles, D.W.1
Chan, A.2
Dirix, L.Y.3
-
41
-
-
79953874259
-
RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
-
N.J. Robert, V. Diéras, J. Glaspy RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer J Clin Oncol 29 2011 1252 1260
-
(2011)
J Clin Oncol
, vol.29
, pp. 1252-1260
-
-
Robert, N.J.1
Diéras, V.2
Glaspy, J.3
-
42
-
-
81155123190
-
RIBBON-2: A randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
A.M. Brufsky, S. Hurvitz, E. Perez RIBBON-2: a randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer J Clin Oncol 29 2011 4286 4293
-
(2011)
J Clin Oncol
, vol.29
, pp. 4286-4293
-
-
Brufsky, A.M.1
Hurvitz, S.2
Perez, E.3
-
43
-
-
77949686134
-
Comparison of subgroup analyses of PFS from three phase III studies of bevacizumab in combination with chemotherapy in patients with HER2-negative metastatic breast cancer
-
abstract 207
-
J. O'Shaughnessy, V. Dieras, J. Glaspy Comparison of subgroup analyses of PFS from three phase III studies of bevacizumab in combination with chemotherapy in patients with HER2-negative metastatic breast cancer Cancer Res 69 suppl 1 2009 abstract 207
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL. 1
-
-
O'Shaughnessy, J.1
Dieras, V.2
Glaspy, J.3
-
44
-
-
84898694397
-
Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: A meta-analysis
-
[Epub ahead of print]
-
J. Cortes, V. Calvo, N. Ramírez-Merino Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis Ann Oncol 2011 Oct 4 [Epub ahead of print]
-
(2011)
Ann Oncol
-
-
Cortes, J.1
Calvo, V.2
Ramírez-Merino, N.3
-
45
-
-
82455194681
-
Impact of bevacizumab (BEV) on efficacy of second-line chemotherapy (CT) for triple-negative breast cancer (TNBC): Analysis of ribbon-2
-
abstract 1010 Accessed: March 28, 2012
-
A. Brufsky, V. Valero, B. Tiangco Impact of bevacizumab (BEV) on efficacy of second-line chemotherapy (CT) for triple-negative breast cancer (TNBC): analysis of ribbon-2 J Clin Oncol 29 suppl 2011 abstract 1010 www.asco.org Accessed: March 28, 2012
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Brufsky, A.1
Valero, V.2
Tiangco, B.3
-
47
-
-
79551520348
-
Treatment-related mortality with bevacizumab in cancer patientsTreatment-related mortality with bevacizumab in cancer patients: A meta-analyssis
-
V. Ranpura, S. Hapani, S. Wu Treatment-related mortality with bevacizumab in cancer patientsTreatment-related mortality with bevacizumab in cancer patients: a meta-analyssis JAMA 305 2011 487 494
-
(2011)
JAMA
, vol.305
, pp. 487-494
-
-
Ranpura, V.1
Hapani, S.2
Wu, S.3
-
49
-
-
34548157209
-
Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine
-
E.A. Perez, G. Lerzo, X. Pivot Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine J Clin Oncol 25 2007 3407 3414
-
(2007)
J Clin Oncol
, vol.25
, pp. 3407-3414
-
-
Perez, E.A.1
Lerzo, G.2
Pivot, X.3
-
50
-
-
34548179878
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy
-
H. Roché, L. Yelle, F. Cognetti Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy J Clin Oncol 25 2007 3415 3420
-
(2007)
J Clin Oncol
, vol.25
, pp. 3415-3420
-
-
Roché, H.1
Yelle, L.2
Cognetti, F.3
-
51
-
-
34548187738
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer
-
E. Thomas, J. Tabernero, M. Fornier Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer J Clin Oncol 25 2007 3399 3406
-
(2007)
J Clin Oncol
, vol.25
, pp. 3399-3406
-
-
Thomas, E.1
Tabernero, J.2
Fornier, M.3
-
52
-
-
36849071808
-
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
-
E.S. Thomas, H.L. Gomez, R.K. Li Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment J Clin Oncol 25 2007 5210 5217
-
(2007)
J Clin Oncol
, vol.25
, pp. 5210-5217
-
-
Thomas, E.S.1
Gomez, H.L.2
Li, R.K.3
-
53
-
-
77954752064
-
Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
J.A. Sparano, E. Vrdoljak, O. Rixe Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane J Clin Oncol 28 2010 3256 3263
-
(2010)
J Clin Oncol
, vol.28
, pp. 3256-3263
-
-
Sparano, J.A.1
Vrdoljak, E.2
Rixe, O.3
-
54
-
-
79251530503
-
Ixabepilone plus capecitabine in metastatic breast cancer patients with reduced performance status previously treated with anthracyclines and taxanes: A pooled analysis by performance status of efficacy and safety data from 2 phase III studies
-
H. Roché, P. Conte, E.A. Perez Ixabepilone plus capecitabine in metastatic breast cancer patients with reduced performance status previously treated with anthracyclines and taxanes: a pooled analysis by performance status of efficacy and safety data from 2 phase III studies Breast Cancer Res Treat 125 2011 755 765
-
(2011)
Breast Cancer Res Treat
, vol.125
, pp. 755-765
-
-
Roché, H.1
Conte, P.2
Perez, E.A.3
-
55
-
-
72149108389
-
Ixabepilone plus capecitabine improves overall survival in symptomatic patients with metastatic breast cancer previously treated with anthracycline and taxane in 2 large phase III studies
-
Paper presented at December 10-14 San Antonio, TX. abstract 6114
-
Conte P, Roché H, Perez E, et al. Ixabepilone plus capecitabine improves overall survival in symptomatic patients with metastatic breast cancer previously treated with anthracycline and taxane in 2 large phase III studies. Paper presented at: 31st Annual San Antonio Breast Cancer Symposium; December 10-14, 2008; San Antonio, TX. abstract 6114.
-
(2008)
31st Annual San Antonio Breast Cancer Symposium
-
-
Conte P, R.1
-
56
-
-
77953025896
-
Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer
-
E.A. Perez, T. Patel, A. Moreno-Aspitia Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer Breast Cancer Res Treat 121 2010 261 271
-
(2010)
Breast Cancer Res Treat
, vol.121
, pp. 261-271
-
-
Perez, E.A.1
Patel, T.2
Moreno-Aspitia, A.3
-
57
-
-
61349093596
-
Triple-negative breast cancer: Current management and future options
-
P.F. Conte, V. Guarneri Triple-negative breast cancer: current management and future options Eur J Cancer Suppl 7 2009 14 18
-
(2009)
Eur J Cancer Suppl
, vol.7
, pp. 14-18
-
-
Conte, P.F.1
Guarneri, V.2
-
58
-
-
79952836195
-
Randomized study of weekly vs every 3 week ixabepilone plus bevacizumab (ixa/bev) vs paclitaxel plus bev (pac/bev) as first-line therapy for metastatic breast cancer (MBC): Final results
-
Abstract 1040 Accessed: March 28, 2012
-
H.S. Rugo, M. Campone, D. Amadori Randomized study of weekly vs every 3 week ixabepilone plus bevacizumab (ixa/bev) vs paclitaxel plus bev (pac/bev) as first-line therapy for metastatic breast cancer (MBC): final results J Clin Oncol 28 suppl 2010 Abstract 1040 www.asco.org Accessed: March 28, 2012
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Rugo, H.S.1
Campone, M.2
Amadori, D.3
-
59
-
-
77949901499
-
Open-label, phase II, multicenter, randomized study of the efficacy and safety of two dose levels of pertuzumab, a human epidermal growth factor receptor 2 dimerization inhibitor, in patients with human epidermal growth factor receptor 2-negative metastatic breast cancer
-
L. Gianni, A. Lladó, G. Bianchi Open-label, phase II, multicenter, randomized study of the efficacy and safety of two dose levels of pertuzumab, a human epidermal growth factor receptor 2 dimerization inhibitor, in patients with human epidermal growth factor receptor 2-negative metastatic breast cancer J Clin Oncol 28 2010 1131 1137
-
(2010)
J Clin Oncol
, vol.28
, pp. 1131-1137
-
-
Gianni, L.1
Lladó, A.2
Bianchi, G.3
-
60
-
-
77949903478
-
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
-
J. Baselga, K.A. Gelmon, S. Verma Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy J Clin Oncol 28 2010 1138 1144
-
(2010)
J Clin Oncol
, vol.28
, pp. 1138-1144
-
-
Baselga, J.1
Gelmon, K.A.2
Verma, S.3
-
61
-
-
84855297353
-
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (neosphere): A randomised multicentre, open-label, phase 2 trial
-
L. Gianni, T. Pienkowski, Y.H. Im Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (neosphere): a randomised multicentre, open-label, phase 2 trial Lancet Oncol 13 2012 25 32
-
(2012)
Lancet Oncol
, vol.13
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
-
62
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
J. Baselga, J. Cortés, S.B. Kim Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer N Engl J Med 366 2012 109 119
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
-
63
-
-
65349194552
-
A phase i study of trastuzumab-DM1, a first-in-class HER2-antibody drug conjugate, in patients with advanced HER2 breast cancer
-
abstract 1028
-
S. Modi, M. Beeram, I.E. Krop A phase I study of trastuzumab-DM1, a first-in-class HER2-antibody drug conjugate, in patients with advanced HER2 breast cancer J Clin Oncol 26 suppl 2008 abstract 1028
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Modi, S.1
Beeram, M.2
Krop, I.E.3
-
64
-
-
79952092706
-
Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy
-
H.A. Burris, H.S. Rugo, S.J. Vukelja Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy J Clin Oncol 29 2011 398 405
-
(2011)
J Clin Oncol
, vol.29
, pp. 398-405
-
-
Burris, H.A.1
Rugo, H.S.2
Vukelja, S.J.3
-
65
-
-
84856617116
-
Trastuzumab emtansine (T-DM1) versus trastuzumabadocetaxel in previously untreated HER2-positive metastatic breast cancer (MBC): Primary results of a randomized, multicenter, open-label phase II study (TDM4450g/BO21976)
-
Paper presented at September 23-27 Stockholm, Sweden. Abstract 5001
-
Hurvitz SA, Dirix L, Kocsis J, et al. Trastuzumab emtansine (T-DM1) versus trastuzumabadocetaxel in previously untreated HER2-positive metastatic breast cancer (MBC): primary results of a randomized, multicenter, open-label phase II study (TDM4450g/BO21976). Paper presented at: European Multidisciplinary Cancer Congress (ECCO/ESMO); September 23-27, 2011; Stockholm, Sweden. Abstract 5001.
-
(2011)
European Multidisciplinary Cancer Congress (ECCO/ESMO)
-
-
Hurvitz, S.A.1
Dirix, L.2
Kocsis, J.3
-
66
-
-
0035256698
-
Untangling the ErbB signaling networkUntangling the ErbB signalling network
-
Y. Yarden, M.X. Sliwkowski Untangling the ErbB signaling networkUntangling the ErbB signalling network Nat Rev Mol Cell Biol 2 2001 127 137
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
67
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
D.J. Slamon, G.M. Clark, S.G. Wong Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Science 235 1987 177 182
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
68
-
-
0024822342
-
Epidermal growth factor receptors in breast cancer: Association with early relapse and death, poor response to hormones and interactions with neu
-
A.L. Harris, S. Nicholson, J.R. Sainsbury Epidermal growth factor receptors in breast cancer: association with early relapse and death, poor response to hormones and interactions with neu J Steroid Biochem 34 1989 123 131
-
(1989)
J Steroid Biochem
, vol.34
, pp. 123-131
-
-
Harris, A.L.1
Nicholson, S.2
Sainsbury, J.R.3
-
69
-
-
0026571910
-
The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients
-
J.G. Klijn, P.M. Berns, P.I. Schmitz The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: a review on 5232 patients Endocr Rev 13 1992 3 17
-
(1992)
Endocr Rev
, vol.13
, pp. 3-17
-
-
Klijn, J.G.1
Berns, P.M.2
Schmitz, P.I.3
-
70
-
-
0028330743
-
The epidermal growth factor receptor as a prognostic marker: Results of 370 patients and review for 3009 patientsThe epidermal growth factor receptor as a prognostic marker: Results of 370 patients and review of 3009 patients
-
S.B. Fox, K. Smith, J. Hollyer The epidermal growth factor receptor as a prognostic marker: results of 370 patients and review for 3009 patientsThe epidermal growth factor receptor as a prognostic marker: results of 370 patients and review of 3009 patients Breast Cancer Res Treat 29 1994 41 49
-
(1994)
Breast Cancer Res Treat
, vol.29
, pp. 41-49
-
-
Fox, S.B.1
Smith, K.2
Hollyer, J.3
-
71
-
-
43549106185
-
Preliminary results of a randomized phase II study of weekly irinotecan/carboplatin with or without cetuximab in patients with metastatic breast cancer
-
abstract 308
-
J. O'Shaughnessy, D. Weckstein, S. Vukelja Preliminary results of a randomized phase II study of weekly irinotecan/carboplatin with or without cetuximab in patients with metastatic breast cancer Breast Cancer Res Treat 106 suppl 1 2007 abstract 308
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.SUPPL. 1
-
-
O'Shaughnessy, J.1
Weckstein, D.2
Vukelja, S.3
-
72
-
-
61349152550
-
TBCRC 001: EGFR inhibition with cetuximab added to carboplatin in metastatic triple negative (basal-like) breast cancer
-
abstract 1009 Accessed: March 29, 2012
-
L. Carey, H. Rugo, P. Marcom TBCRC 001: EGFR inhibition with cetuximab added to carboplatin in metastatic triple negative (basal-like) breast cancer J Clin Oncol 26 suppl 2008 abstract 1009 www.asco.org Accessed: March 29, 2012
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Carey, L.1
Rugo, H.2
Marcom, P.3
-
73
-
-
78649760941
-
The addition of cetuximab to cisplatin increases overall response rate (ORR) and progression-free survival (PFS) in metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II study (BALI-1)
-
(abstract 274O)
-
J. Baselga, P. Gomez, A. Awada The addition of cetuximab to cisplatin increases overall response rate (ORR) and progression-free survival (PFS) in metastatic triple-negative breast cancer (TNBC): results of a randomized phase II study (BALI-1) Ann Oncol 21 suppl 8 2010 vii96 (abstract 274O)
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL. 8
, pp. 96
-
-
Baselga, J.1
Gomez, P.2
Awada, A.3
-
74
-
-
79951841310
-
Exploratory subset analysis according to prior endocrine treatment of two randomized phase II trials comparing gefitinib with placebo in combination with tamoxifen or anastrozole in hormone receptor+ metastatic breast cancer
-
abstract 1014 Accessed: March 29, 2012
-
M. Cristofanilli, R. Schiff, V. Valero Exploratory subset analysis according to prior endocrine treatment of two randomized phase II trials comparing gefitinib with placebo in combination with tamoxifen or anastrozole in hormone receptor+ metastatic breast cancer J Clin Oncol 27 suppl 2009 abstract 1014 www.asco.org Accessed: March 29, 2012
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Cristofanilli, M.1
Schiff, R.2
Valero, V.3
-
75
-
-
34247857540
-
Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: A review of four phase i trials in patients with advanced refractory solid tumors
-
D. Strumberg, J.W. Clark, A. Awada Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors Oncologist 12 2007 426 437
-
(2007)
Oncologist
, vol.12
, pp. 426-437
-
-
Strumberg, D.1
Clark, J.W.2
Awada, A.3
-
76
-
-
33644986559
-
A phase II multicentre uncontrolled trial of sorafenib (BAY 43-9006) in patients with metastatic breast cancer
-
abstract 276
-
G. Bianchi, S. Loibl, C. Zamagni A phase II multicentre uncontrolled trial of sorafenib (BAY 43-9006) in patients with metastatic breast cancer Eur J Cancer 3 suppl 2 2005 abstract 276
-
(2005)
Eur J Cancer
, vol.3
, Issue.SUPPL. 2
-
-
Bianchi, G.1
Loibl, S.2
Zamagni, C.3
-
77
-
-
33749263319
-
BAY 43-9006 as single oral agent in patients with metastatic breast cancer previously exposed to anthracycline and/or taxane
-
abstract 577 Accessed: March 29, 2012
-
A. Moreno-Aspitia, D.W. Hillman, M. Wiesenfeld BAY 43-9006 as single oral agent in patients with metastatic breast cancer previously exposed to anthracycline and/or taxane J Clin Oncol 24 suppl 2006 abstract 577 www.asco.org Accessed: March 29, 2012
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Moreno-Aspitia, A.1
Hillman, D.W.2
Wiesenfeld, M.3
-
78
-
-
58149335533
-
Phase II trial of sorafenib in patients with metastatic breast cancer previously exposed to anthracyclines or taxanes: North Central Cancer Treatment Group and Mayo Clinic trial N0336
-
A. Moreno-Aspitia, R.F. Morton, D.W. Hillman Phase II trial of sorafenib in patients with metastatic breast cancer previously exposed to anthracyclines or taxanes: North Central Cancer Treatment Group and Mayo Clinic trial N0336 J Clin Oncol 27 2009 11 15
-
(2009)
J Clin Oncol
, vol.27
, pp. 11-15
-
-
Moreno-Aspitia, A.1
Morton, R.F.2
Hillman, D.W.3
-
79
-
-
77952470230
-
A double-blind, randomized, placebo-controlled, phase 2b study evaluating the efficacy and safety of sorafenib (SOR) in combination with paclitaxel (PAC) as first-line therapy in patients (pts) with locally recurrent or metastatic breast cancer (BC)
-
Paper presented at: December 9-13; San Antonio, TX. Abstract 44
-
Gradishar WJ, Kaklamani V, Prasad Sahoo T, et al. A double-blind, randomized, placebo-controlled, phase 2b study evaluating the efficacy and safety of sorafenib (SOR) in combination with paclitaxel (PAC) as first-line therapy in patients (pts) with locally recurrent or metastatic breast cancer (BC). Paper presented at: 32nd San Antonio Breast Cancer Symposium; December 9-13; San Antonio, TX. Abstract 44.
-
32nd San Antonio Breast Cancer Symposium
-
-
Gradishar, W.J.1
Kaklamani, V.2
Prasad Sahoo, T.3
-
80
-
-
77954654158
-
Solti-0701: A double-blind, randomized phase 2b study evaluating the efficacy and safety of sorafenib (SOR) compared to placebo (PL) when administered in combination with capecitabine (CAP) in patients (pts) with locally advanced breast cancer (adv BC)
-
abstract 3LBA
-
J. Baselga, J.G.M. Segalla, H. Roché Solti-0701: a double-blind, randomized phase 2b study evaluating the efficacy and safety of sorafenib (SOR) compared to placebo (PL) when administered in combination with capecitabine (CAP) in patients (pts) with locally advanced breast cancer (adv BC) Eur J Cancer 7 suppl 3 2009 abstract 3LBA
-
(2009)
Eur J Cancer
, vol.7
, Issue.SUPPL. 3
-
-
Baselga, J.1
Segalla, J.G.M.2
Roché, H.3
-
81
-
-
84858642912
-
Sorafenib (SOR) plus chemotherapy (CRx) for patients (pts) with advanced (adv) breast cancer (BC) previously treated with bevacizumab (BEV)
-
abstract 1009 Accessed: March 29, 2012
-
C. Hudis, K.W. Tauer, R.C. Hermann Sorafenib (SOR) plus chemotherapy (CRx) for patients (pts) with advanced (adv) breast cancer (BC) previously treated with bevacizumab (BEV) J Clin Oncol 29 suppl 2011 abstract 1009 www.asco.org Accessed: March 29, 2012
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Hudis, C.1
Tauer, K.W.2
Hermann, R.C.3
-
82
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
D.B. Mendel, A.D. Laird, X. Xin In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship Clin Cancer Res 9 2003 327 337
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
83
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
S. Faivre, C. Delbaldo, K. Vera Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer J Clin Oncol 24 2006 25 35
-
(2006)
J Clin Oncol
, vol.24
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
-
84
-
-
42949148257
-
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
H.J. Burstein, A.D. Elias, H.S. Rugo Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane J Clin Oncol 26 2008 1810 1816
-
(2008)
J Clin Oncol
, vol.26
, pp. 1810-1816
-
-
Burstein, H.J.1
Elias, A.D.2
Rugo, H.S.3
-
85
-
-
77957604275
-
SABRE-B: An evaluation of paclitaxel and bevacizumab with or without sunitinib as first-line treatment of metastatic breast cancer
-
E.L. Mayer, S. Dhakil, T. Patel SABRE-B: an evaluation of paclitaxel and bevacizumab with or without sunitinib as first-line treatment of metastatic breast cancer Ann Oncol 21 2010 2371 2376
-
(2010)
Ann Oncol
, vol.21
, pp. 2371-2376
-
-
Mayer, E.L.1
Dhakil, S.2
Patel, T.3
-
86
-
-
77955894152
-
Phase II trial of sunitinib (SU) in combination with capecitabine (C) versus C in previously treated advanced breast cancer (ABC)
-
abstract LBA 1011
-
J. Crown, V. Dieras, E. Staroslawska Phase II trial of sunitinib (SU) in combination with capecitabine (C) versus C in previously treated advanced breast cancer (ABC) J Clin Oncol 28 suppl 2010 abstract LBA 1011
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Crown, J.1
Dieras, V.2
Staroslawska, E.3
-
87
-
-
77955911251
-
Sunitinib (SU) in combination with docetaxel (D) versus D alone for the first-line treatment of advanced breast cancer (ABC)
-
abstract LBA 1010
-
J. Bergh, R. Greil, N. Voytko Sunitinib (SU) in combination with docetaxel (D) versus D alone for the first-line treatment of advanced breast cancer (ABC) J Clin Oncol 28 suppl 2010 abstract LBA 1010
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Bergh, J.1
Greil, R.2
Voytko, N.3
-
88
-
-
77951296573
-
Phase III randomized trial of sunitinib vs. capecitabine in patients with previously treated HER2-negative advanced breast cancerPhase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
-
C.H. Barrios, M.C. Liu, S.C. Lee Phase III randomized trial of sunitinib vs. capecitabine in patients with previously treated HER2-negative advanced breast cancerPhase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer Breast Cancer Res Treat 121 2010 121 131
-
(2010)
Breast Cancer Res Treat
, vol.121
, pp. 121-131
-
-
Barrios, C.H.1
Liu, M.C.2
Lee, S.C.3
-
89
-
-
80052483131
-
Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: Possible combinations in solid tumors
-
J.C. Montero, S. Seoane, A. Ocaña Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors Clin Cancer Res 17 2011 5546 5552
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5546-5552
-
-
Montero, J.C.1
Seoane, S.2
Ocaña, A.3
-
90
-
-
80052505248
-
Src: A potential target for the treatment of triple-negative breast cancer
-
D. Tryfonopoulos, S. Walsh, D.M. Collins Src: a potential target for the treatment of triple-negative breast cancer Ann Oncol 22 2011 2234 2240
-
(2011)
Ann Oncol
, vol.22
, pp. 2234-2240
-
-
Tryfonopoulos, D.1
Walsh, S.2
Collins, D.M.3
-
91
-
-
80455173400
-
Dasatinib as a single agent in triple-negative breast cancer: Results of an open-label phase 2 study
-
R.S. Finn, C. Bengala, N. Ibrahim Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study Clin Cancer Res 17 2011 6905 6913
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6905-6913
-
-
Finn, R.S.1
Bengala, C.2
Ibrahim, N.3
-
92
-
-
80052860747
-
Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing
-
C.I. Herold, V. Chadaram, B.L. Peterson Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing Clin Cancer Res 17 2011 6061 6070
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6061-6070
-
-
Herold, C.I.1
Chadaram, V.2
Peterson, B.L.3
-
93
-
-
80455132309
-
A phase 2 trial of dasatinib in patients with advanced HER2-positive and/or hormone receptor+ breast cancer
-
E.L. Mayer, J.F. Baurain, J. Sparano A phase 2 trial of dasatinib in patients with advanced HER2-positive and/or hormone receptor+ breast cancer Clin Cancer Res 17 2011 6897 6904
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6897-6904
-
-
Mayer, E.L.1
Baurain, J.F.2
Sparano, J.3
-
94
-
-
77952114407
-
Development of candidate genomic markers to select breast cancer patients for dasatinib therapy
-
S. Moulder, K. Yan, F. Huang Development of candidate genomic markers to select breast cancer patients for dasatinib therapy Mol Cancer Ther 9 2010 1120 1127
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1120-1127
-
-
Moulder, S.1
Yan, K.2
Huang, F.3
-
95
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
B.T. Hennessy, D.L. Smith, P.T. Ram Exploiting the PI3K/AKT pathway for cancer drug discovery Nat Rev Drug Discov 4 2005 988 1004
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
-
96
-
-
28244479028
-
Breast cancer associated PI3KCA mutations are oncogenic in mammary epithelial cells
-
S.J. Isakoff, J.A. Engelman, H.Y. Irie Breast cancer associated PI3KCA mutations are oncogenic in mammary epithelial cells Cancer Res 65 2006 10992 11000
-
(2006)
Cancer Res
, vol.65
, pp. 10992-11000
-
-
Isakoff, S.J.1
Engelman, J.A.2
Irie, H.Y.3
-
97
-
-
37149020235
-
The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: Results of a phase i study with pharmacokinetics
-
A. Awada, F. Cardoso, C. Fontaine The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics Eur J Cancer 44 2008 84 91
-
(2008)
Eur J Cancer
, vol.44
, pp. 84-91
-
-
Awada, A.1
Cardoso, F.2
Fontaine, C.3
-
98
-
-
78650984926
-
Phase i study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab
-
F. Andre, M. Campone, R. O'Regan Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab J Clin Oncol 28 2010 5110 5115
-
(2010)
J Clin Oncol
, vol.28
, pp. 5110-5115
-
-
Andre, F.1
Campone, M.2
O'Regan, R.3
-
99
-
-
73649109111
-
Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163
-
S.L. Ellard, M. Clemons, K.A. Gelmon Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163 J Clin Oncol 27 2009 4536 4541
-
(2009)
J Clin Oncol
, vol.27
, pp. 4536-4541
-
-
Ellard, S.L.1
Clemons, M.2
Gelmon, K.A.3
-
100
-
-
79951814007
-
TAMRAD: A GINECO randomized phase II trial of everolimus in combination with tamoxifen versus tamoxifen alone in patients (pts) with hormone-receptor-positive, HER2 negative metastatic breast cancer (MBC) with prior exposure to aromatase inhibitors (AI)
-
Paper presented at December 8-12; San Antonio, TX. Abstract S1-6
-
Bachelot T, Bourgier C, Cropet C, et al. TAMRAD: A GINECO randomized phase II trial of everolimus in combination with tamoxifen versus tamoxifen alone in patients (pts) with hormone-receptor-positive, HER2 negative metastatic breast cancer (MBC) with prior exposure to aromatase inhibitors (AI). Paper presented at: 33rd Annual San Antonio Breast Cancer Symposium; December 8-12; San Antonio, TX. Abstract S1-6.
-
33rd Annual San Antonio Breast Cancer Symposium
-
-
Bachelot, T.1
Bourgier, C.2
Cropet, C.3
-
101
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
J. Baselga, M. Campone, M. Piccart Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer N Engl J Med 366 2012 520 529
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
-
103
-
-
77956657460
-
Poly(ADP-ribose) polymerase as a novel therapeutic target in cancerPoly (ADP-ribose) polymerase as a novel therapeutic target in cancer
-
C.M. Annunziata, J. O'Shaughnessy Poly(ADP-ribose) polymerase as a novel therapeutic target in cancerPoly (ADP-ribose) polymerase as a novel therapeutic target in cancer Clin Cancer Res 16 2010 4517 4526
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4517-4526
-
-
Annunziata, C.M.1
O'Shaughnessy, J.2
-
104
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
J. O'Shaughnessy, C. Osborne, J.E. Pippen Iniparib plus chemotherapy in metastatic triple-negative breast cancer N Engl J Med 364 2011 205 214
-
(2011)
N Engl J Med
, vol.364
, pp. 205-214
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.E.3
-
105
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
P.C. Fong, T.A. Yap, D.S. Boss Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval J Clin Oncol 28 2010 2512 2519
-
(2010)
J Clin Oncol
, vol.28
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
-
106
-
-
33745876586
-
Inhibition of poly(ADP-ribose) polymerase in cancer
-
E.R. Plummer Inhibition of poly(ADP-ribose) polymerase in cancer Curr Opin Pharmacol 6 2006 364 368
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 364-368
-
-
Plummer, E.R.1
-
107
-
-
80052330662
-
A randomized phase III study of iniparib (BSI-201) in combination with gemcitabine/carboplatin (G/C) in metastatic triple-negative breast cancer (TNBC)
-
abstract 1007
-
J. O'Shaughnessy, L.S. Schwartzberg, M.A. Danso A randomized phase III study of iniparib (BSI-201) in combination with gemcitabine/carboplatin (G/C) in metastatic triple-negative breast cancer (TNBC) J Clin Oncol 29 suppl 2011 abstract 1007
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
O'Shaughnessy, J.1
Schwartzberg, L.S.2
Danso, M.A.3
-
108
-
-
84862907868
-
Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor
-
X. Liu, Y. Shi, D.X. Maag Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor Clin Cancer Res 18 2012 510 523
-
(2012)
Clin Cancer Res
, vol.18
, pp. 510-523
-
-
Liu, X.1
Shi, Y.2
Maag, D.X.3
-
109
-
-
84858198901
-
Failure of iniparib to inhibit poly(ADP-ribose) polymerase in vitro
-
A.G. Patel, S. De Lorenzo, K. Flatten Failure of iniparib to inhibit poly(ADP-ribose) polymerase in vitro Clin Cancer Res 18 2012 1655 1662
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1655-1662
-
-
Patel, A.G.1
De Lorenzo, S.2
Flatten, K.3
-
110
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
A. Tutt, M. Robson, J.E. Garber Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial Lancet 376 2010 235 244
-
(2010)
Lancet
, vol.376
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
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