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Volumn 39, Issue 2, 2012, Pages 345-362

Pharmacologic Issues in Management of Chronic Disease

Author keywords

Adherence; Adverse drug events; Inappropriate prescribing; Polypharmacy

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; CARDIOVASCULAR AGENT; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HORMONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OPIATE DERIVATIVE; VITAMIN D; WARFARIN;

EID: 84861168161     PISSN: 00954543     EISSN: 1558299X     Source Type: Journal    
DOI: 10.1016/j.pop.2012.03.007     Document Type: Review
Times cited : (14)

References (84)
  • 1
    • 45749111537 scopus 로고    scopus 로고
    • Slone Epidemiology Center at Boston University Web site, Available at:, Accessed August 15, 2011
    • Patterns of medication use in the United States 2006: a report from the Slone Survey 2011, Slone Epidemiology Center at Boston University Web site, Available at:, Accessed August 15, 2011. http://www.bu.edu/slone/SloneSurvey/AnnualRpt/SloneSurveyWebReport2006.pdf.
    • (2011) Patterns of medication use in the United States 2006: a report from the Slone Survey
  • 2
    • 58149269468 scopus 로고    scopus 로고
    • Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States
    • Qato D.M., Alexander G.C., Conti R.M., et al. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA 2008, 300(24):2867-2878.
    • (2008) JAMA , vol.300 , Issue.24 , pp. 2867-2878
    • Qato, D.M.1    Alexander, G.C.2    Conti, R.M.3
  • 3
    • 67649819484 scopus 로고    scopus 로고
    • Concomitant use of prescription drugs and dietary supplements in ambulatory elderly people
    • Nahin R.L., Pecha M., Welmerink D.B., et al. Concomitant use of prescription drugs and dietary supplements in ambulatory elderly people. J Am Geriatr Soc 2009, 57(7):1197-1205.
    • (2009) J Am Geriatr Soc , vol.57 , Issue.7 , pp. 1197-1205
    • Nahin, R.L.1    Pecha, M.2    Welmerink, D.B.3
  • 4
    • 78650762905 scopus 로고    scopus 로고
    • Deaths: preliminary data for 2010
    • National vital statistics reports,. Hyattsville (MD): National Center for Health Statistics; 2012. Available at: Accessed January 15
    • Murphy SL, Xu J, Kochanek KD. Deaths: preliminary data for 2010. National vital statistics reports, vol. 60(4). Hyattsville (MD): National Center for Health Statistics; 2012. Available at: Accessed January 15, 2012. http://www.cdc.gov/nchs/data/nvsr/nvsr60/nvsr60_04.pdf.
    • (2012) , vol.60 , Issue.4
    • Murphy, S.L.1    Xu, J.2    Kochanek, K.D.3
  • 6
    • 27744586186 scopus 로고    scopus 로고
    • Health outcomes and polypharmacy in elderly individuals
    • Frazier S.C. Health outcomes and polypharmacy in elderly individuals. J Gerontol Nurs 2005, 31(9):4-11.
    • (2005) J Gerontol Nurs , vol.31 , Issue.9 , pp. 4-11
    • Frazier, S.C.1
  • 7
    • 67749134070 scopus 로고    scopus 로고
    • Patterns of drug use and factors associated with polypharmacy and excessive polypharmacy in elderly persons
    • Jyrkka J., Enlund H., Korhonen M.J., et al. Patterns of drug use and factors associated with polypharmacy and excessive polypharmacy in elderly persons. Drugs Aging 2009, 26(6):493-503.
    • (2009) Drugs Aging , vol.26 , Issue.6 , pp. 493-503
    • Jyrkka, J.1    Enlund, H.2    Korhonen, M.J.3
  • 8
    • 0141538307 scopus 로고    scopus 로고
    • Reduction of polypharmacy in the elderly: a systematic review of the role of the pharmacist
    • Rollason V., Vogt N. Reduction of polypharmacy in the elderly: a systematic review of the role of the pharmacist. Drugs Aging 2003, 20(11):817-832.
    • (2003) Drugs Aging , vol.20 , Issue.11 , pp. 817-832
    • Rollason, V.1    Vogt, N.2
  • 9
    • 35748946027 scopus 로고    scopus 로고
    • Inappropriate polypharmacy: reducing the burden of multiple medication
    • Milton J.C., Jackson S.H. Inappropriate polypharmacy: reducing the burden of multiple medication. Clin Med 2007, 7(5):514-517.
    • (2007) Clin Med , vol.7 , Issue.5 , pp. 514-517
    • Milton, J.C.1    Jackson, S.H.2
  • 10
    • 0029920270 scopus 로고    scopus 로고
    • Factors predicting change in prescription and nonprescription drug use in a community-residing black and white elderly population
    • Fillenbaum G.G., Horner R.D., Hanlon J.T., et al. Factors predicting change in prescription and nonprescription drug use in a community-residing black and white elderly population. J Clin Epidemiol 1996, 49:587-593.
    • (1996) J Clin Epidemiol , vol.49 , pp. 587-593
    • Fillenbaum, G.G.1    Horner, R.D.2    Hanlon, J.T.3
  • 11
    • 77957938650 scopus 로고    scopus 로고
    • Feasibility study of a systematic approach for discontinuation of multiple medications in older adults
    • Garfinkel D., Mangin D. Feasibility study of a systematic approach for discontinuation of multiple medications in older adults. Arch Intern Med 2010, 170(18):1648-1654.
    • (2010) Arch Intern Med , vol.170 , Issue.18 , pp. 1648-1654
    • Garfinkel, D.1    Mangin, D.2
  • 12
    • 0032984738 scopus 로고    scopus 로고
    • Polypharmacy management in Medicare managed care: changes in prescribing by primary care physicians resulting from a program promoting medication reviews
    • Fillit H.M., Futterman R., Orland B.I., et al. Polypharmacy management in Medicare managed care: changes in prescribing by primary care physicians resulting from a program promoting medication reviews. Am J Manag Care 1999, 5(5):587-594.
    • (1999) Am J Manag Care , vol.5 , Issue.5 , pp. 587-594
    • Fillit, H.M.1    Futterman, R.2    Orland, B.I.3
  • 13
    • 27644598241 scopus 로고    scopus 로고
    • Reduction of high-risk polypharmacy drug combinations in patients in a managed care setting
    • Zarowitz B.J., Stebelsky L.A., Muma B.K., et al. Reduction of high-risk polypharmacy drug combinations in patients in a managed care setting. Pharmacotherapy 2005, 25(11):1636-1645.
    • (2005) Pharmacotherapy , vol.25 , Issue.11 , pp. 1636-1645
    • Zarowitz, B.J.1    Stebelsky, L.A.2    Muma, B.K.3
  • 14
    • 0036832049 scopus 로고    scopus 로고
    • The continuing challenge of inappropriate prescribing in the elderly: an update of the evidence
    • Liu G.G., Christensen D.B. The continuing challenge of inappropriate prescribing in the elderly: an update of the evidence. J Am Pharm Assoc (Wash) 2002, 42(6):847-857.
    • (2002) J Am Pharm Assoc (Wash) , vol.42 , Issue.6 , pp. 847-857
    • Liu, G.G.1    Christensen, D.B.2
  • 15
    • 38549109081 scopus 로고    scopus 로고
    • Inappropriate prescribing in an acutely ill population of elderly patients as determined by Beers' Criteria
    • Gallagher P.F., Barry P.J., Ryan C., et al. Inappropriate prescribing in an acutely ill population of elderly patients as determined by Beers' Criteria. Age Ageing 2008, 37(1):96-101.
    • (2008) Age Ageing , vol.37 , Issue.1 , pp. 96-101
    • Gallagher, P.F.1    Barry, P.J.2    Ryan, C.3
  • 16
    • 56749164053 scopus 로고    scopus 로고
    • STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria
    • Gallagher P., O'Mahony D. STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria. Age Ageing 2008, 37(6):673-679.
    • (2008) Age Ageing , vol.37 , Issue.6 , pp. 673-679
    • Gallagher, P.1    O'Mahony, D.2
  • 17
    • 37149000545 scopus 로고    scopus 로고
    • START (screening tool to alert doctors to the right treatment)-an evidence-based screening tool to detect prescribing omissions in elderly patients
    • Barry P.J., Gallagher P., Ryan C., et al. START (screening tool to alert doctors to the right treatment)-an evidence-based screening tool to detect prescribing omissions in elderly patients. Age Ageing 2007, 36(6):632-638.
    • (2007) Age Ageing , vol.36 , Issue.6 , pp. 632-638
    • Barry, P.J.1    Gallagher, P.2    Ryan, C.3
  • 18
    • 38449106799 scopus 로고    scopus 로고
    • Medication use leading to emergency department visits for adverse drug events in older adults
    • Budnitz D.S., Shehab N., Kegler S.R., et al. Medication use leading to emergency department visits for adverse drug events in older adults. Ann Intern Med 2007, 147(11):755-765.
    • (2007) Ann Intern Med , vol.147 , Issue.11 , pp. 755-765
    • Budnitz, D.S.1    Shehab, N.2    Kegler, S.R.3
  • 19
    • 34447308781 scopus 로고    scopus 로고
    • Appropriate prescribing in elderly people: how well can it be measured and optimised?
    • Spinewine A., Schmader K.E., Barber N., et al. Appropriate prescribing in elderly people: how well can it be measured and optimised?. Lancet 2007, 370(9582):173-184.
    • (2007) Lancet , vol.370 , Issue.9582 , pp. 173-184
    • Spinewine, A.1    Schmader, K.E.2    Barber, N.3
  • 20
    • 80052395734 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011
    • What is a serious adverse event? 2011, U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011. http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm.
    • (2011) What is a serious adverse event?
  • 21
    • 1642407902 scopus 로고
    • European Agency for the Evaluation of Medicinal Products, Human Medicines Evaluation Unit, Available at:, Accessed January 13, 2012
    • Clinical safety data management: definitions and standards for expedited reporting 1995, European Agency for the Evaluation of Medicinal Products, Human Medicines Evaluation Unit, Available at:, Accessed January 13, 2012. http://eudravigilance.ema.europa.eu/human/docs/e2a.pdf.
    • (1995) Clinical safety data management: definitions and standards for expedited reporting
  • 22
    • 46249126174 scopus 로고    scopus 로고
    • Potentially inappropriate medications and adverse drug effects in elders in the ED
    • Nixdorff N., Hustey F.M., Brady A.K., et al. Potentially inappropriate medications and adverse drug effects in elders in the ED. Am J Emerg Med 2008, 26(6):697-700.
    • (2008) Am J Emerg Med , vol.26 , Issue.6 , pp. 697-700
    • Nixdorff, N.1    Hustey, F.M.2    Brady, A.K.3
  • 23
    • 0031012726 scopus 로고    scopus 로고
    • The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group
    • Bates D.W., Spell N., Cullen D.J. The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group. JAMA 1997, 277(4):307-311.
    • (1997) JAMA , vol.277 , Issue.4 , pp. 307-311
    • Bates, D.W.1    Spell, N.2    Cullen, D.J.3
  • 24
    • 0028024127 scopus 로고
    • A summated score for the Medication Appropriateness Index: development and assessment of clinimetric properties including content validity
    • Samsa G.P., Hanlon J.T., Schmader K.E. A summated score for the Medication Appropriateness Index: development and assessment of clinimetric properties including content validity. J Clin Epidemiol 1994, 47(8):891-896.
    • (1994) J Clin Epidemiol , vol.47 , Issue.8 , pp. 891-896
    • Samsa, G.P.1    Hanlon, J.T.2    Schmader, K.E.3
  • 25
    • 0025954423 scopus 로고
    • UCLA Division of Geriatric Medicine. Explicit criteria for determining inappropriate medication use in nursing home residents
    • Beers M.H., Ouslander J.G., Rollingher I., et al. UCLA Division of Geriatric Medicine. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med 1991, 151(9):1825-1832.
    • (1991) Arch Intern Med , vol.151 , Issue.9 , pp. 1825-1832
    • Beers, M.H.1    Ouslander, J.G.2    Rollingher, I.3
  • 26
    • 0030802061 scopus 로고    scopus 로고
    • Explicit criteria for determining potentially inappropriate medication use by the elderly: an update
    • Beers M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med 1997, 157(14):1531-1536.
    • (1997) Arch Intern Med , vol.157 , Issue.14 , pp. 1531-1536
    • Beers, M.H.1
  • 27
    • 0345600187 scopus 로고    scopus 로고
    • Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts
    • Fick D.M., Cooper J.W., Wade W.E., et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003, 163(22):2716-2724.
    • (2003) Arch Intern Med , vol.163 , Issue.22 , pp. 2716-2724
    • Fick, D.M.1    Cooper, J.W.2    Wade, W.E.3
  • 28
    • 0035852040 scopus 로고    scopus 로고
    • Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey
    • Zhan C., Sangl J., Bierman A.S., et al. Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. JAMA 2001, 286(22):2823-2829.
    • (2001) JAMA , vol.286 , Issue.22 , pp. 2823-2829
    • Zhan, C.1    Sangl, J.2    Bierman, A.S.3
  • 29
    • 19444380378 scopus 로고    scopus 로고
    • Use of the beers criteria to predict adverse drug reactions among first-visit elderly outpatients
    • Chang C.M., Liu P.Y., Yang Y.H., et al. Use of the beers criteria to predict adverse drug reactions among first-visit elderly outpatients. Pharmacotherapy 2005, 25(6):831-838.
    • (2005) Pharmacotherapy , vol.25 , Issue.6 , pp. 831-838
    • Chang, C.M.1    Liu, P.Y.2    Yang, Y.H.3
  • 30
    • 33644938429 scopus 로고    scopus 로고
    • Adverse drug reactions in an elderly hospitalised population: inappropriate prescription is a leading cause
    • Passarelli M.C., Jacob-Filho W., Figueras A. Adverse drug reactions in an elderly hospitalised population: inappropriate prescription is a leading cause. Drugs Aging 2005, 22(9):767-777.
    • (2005) Drugs Aging , vol.22 , Issue.9 , pp. 767-777
    • Passarelli, M.C.1    Jacob-Filho, W.2    Figueras, A.3
  • 31
    • 66549125080 scopus 로고    scopus 로고
    • Inappropriate medication use as a risk factor for self-reported adverse drug effects in older adults
    • Chrischilles E.A., VanGilder R., Wright K., et al. Inappropriate medication use as a risk factor for self-reported adverse drug effects in older adults. J Am Geriatr Soc 2009, 57(6):1000-1006.
    • (2009) J Am Geriatr Soc , vol.57 , Issue.6 , pp. 1000-1006
    • Chrischilles, E.A.1    VanGilder, R.2    Wright, K.3
  • 32
    • 84861119889 scopus 로고    scopus 로고
    • National Committee for Quality Assurance
    • Available at: Accessed August 15
    • National Committee for Quality Assurance. NCQA Releases HEDIS 2006; New measures address overuse, follow-up. Available at: Accessed August 15, 2011. http://www.ncqa.org/tabid/277/Default.aspx.
    • (2011) NCQA Releases HEDIS 2006; New measures address overuse, follow-up
  • 33
    • 84861137608 scopus 로고    scopus 로고
    • National Committee for Quality Assurance
    • HEDIS, & quality measurement. Available at: Accessed August 15
    • National Committee for Quality Assurance. HEDIS, & quality measurement. Available at: Accessed August 15, 2011. http://www.ncqa.org/tabid/59/Default.aspx.
    • (2011)
  • 34
    • 77952930358 scopus 로고    scopus 로고
    • Inappropriate prescribing predicts adverse drug events in older adults
    • Lund B.C., Carnahan R.M., Egge J.A., et al. Inappropriate prescribing predicts adverse drug events in older adults. Ann Pharmacother 2010, 44(6):957-963.
    • (2010) Ann Pharmacother , vol.44 , Issue.6 , pp. 957-963
    • Lund, B.C.1    Carnahan, R.M.2    Egge, J.A.3
  • 35
    • 0031010731 scopus 로고    scopus 로고
    • Reliability of a modified medication appropriateness index in ambulatory older persons
    • Fitzgerald L.S., Hanlon J.T., Shelton P.S., et al. Reliability of a modified medication appropriateness index in ambulatory older persons. Ann Pharmacother 1997, 31(5):543-548.
    • (1997) Ann Pharmacother , vol.31 , Issue.5 , pp. 543-548
    • Fitzgerald, L.S.1    Hanlon, J.T.2    Shelton, P.S.3
  • 36
    • 39049123608 scopus 로고    scopus 로고
    • STOPP (Screening Toll of Older Persons' Prescriptions) and START (screening tool to alert doctors to right treatment): consensus validation
    • Gallagher P., Ryan C., Byrne S., et al. STOPP (Screening Toll of Older Persons' Prescriptions) and START (screening tool to alert doctors to right treatment): consensus validation. Int J Clin Pharmacol Ther 2008, 46:72-83.
    • (2008) Int J Clin Pharmacol Ther , vol.46 , pp. 72-83
    • Gallagher, P.1    Ryan, C.2    Byrne, S.3
  • 37
    • 85027951831 scopus 로고    scopus 로고
    • Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria
    • Gallagher P.F., O'Connor M.N., O'Mahony D. Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria. Clin Pharmacol Ther 2011, 89(6):845-854.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.6 , pp. 845-854
    • Gallagher, P.F.1    O'Connor, M.N.2    O'Mahony, D.3
  • 38
    • 79959296825 scopus 로고    scopus 로고
    • Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients
    • Hamilton H., Gallagher P., Ryan C., et al. Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med 2011, 171(11):1013-1019.
    • (2011) Arch Intern Med , vol.171 , Issue.11 , pp. 1013-1019
    • Hamilton, H.1    Gallagher, P.2    Ryan, C.3
  • 39
    • 33750301096 scopus 로고    scopus 로고
    • Medication adherence and persistence as the cornerstone of effective antihypertensive therapy
    • Burnier M. Medication adherence and persistence as the cornerstone of effective antihypertensive therapy. Am J Hypertens 2006, 19(11):1190-1196.
    • (2006) Am J Hypertens , vol.19 , Issue.11 , pp. 1190-1196
    • Burnier, M.1
  • 40
    • 77951102841 scopus 로고    scopus 로고
    • Primary medication non-adherence: analysis of 195,930 electronic prescriptions
    • Fischer M.A., Stedman M.R., Lii J., et al. Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med 2010, 25(4):284-290.
    • (2010) J Gen Intern Med , vol.25 , Issue.4 , pp. 284-290
    • Fischer, M.A.1    Stedman, M.R.2    Lii, J.3
  • 41
    • 65449169135 scopus 로고    scopus 로고
    • Barriers to and determinants of medication adherence in hypertension management: perspective of the cohort study of medication adherence among older adults
    • Krousel-Wood M.A., Muntner P., Islam T., et al. Barriers to and determinants of medication adherence in hypertension management: perspective of the cohort study of medication adherence among older adults. Med Clin North Am 2009, 93(3):753-769.
    • (2009) Med Clin North Am , vol.93 , Issue.3 , pp. 753-769
    • Krousel-Wood, M.A.1    Muntner, P.2    Islam, T.3
  • 42
    • 77952552600 scopus 로고    scopus 로고
    • World Health Organization, Available at:, Accessed August 15, 2011
    • Adherence to long-term therapy: evidence for action 2003, World Health Organization, Available at:, Accessed August 15, 2011. http://www.who.int/chp/knowledge/publications/adherence_introduction.pdf.
    • (2003) Adherence to long-term therapy: evidence for action
  • 43
    • 67649523031 scopus 로고    scopus 로고
    • Medication adherence: its importance in cardiovascular outcomes
    • Ho P.M., Bryson C.L., Rumsfeld J.S. Medication adherence: its importance in cardiovascular outcomes. Circulation 2009, 119(23):3028-3035.
    • (2009) Circulation , vol.119 , Issue.23 , pp. 3028-3035
    • Ho, P.M.1    Bryson, C.L.2    Rumsfeld, J.S.3
  • 44
    • 67349227964 scopus 로고    scopus 로고
    • Risk factors for poor adherence to eyedrops in electronically monitored patients with glaucoma
    • Friedman D.S., Okeke C.O., Jampel H.D., et al. Risk factors for poor adherence to eyedrops in electronically monitored patients with glaucoma. Ophthalmology 2009, 116(6):1097-1105.
    • (2009) Ophthalmology , vol.116 , Issue.6 , pp. 1097-1105
    • Friedman, D.S.1    Okeke, C.O.2    Jampel, H.D.3
  • 45
    • 71549115759 scopus 로고    scopus 로고
    • Predictors of medication nonadherence among patients with diabetes in Medicare Part D programs: a retrospective cohort study
    • [discussion: 2150-51]
    • Yang Y., Thumula V., Pace P.F., et al. Predictors of medication nonadherence among patients with diabetes in Medicare Part D programs: a retrospective cohort study. Clin Ther 2009, 31(10):2178-2188. [discussion: 2150-51].
    • (2009) Clin Ther , vol.31 , Issue.10 , pp. 2178-2188
    • Yang, Y.1    Thumula, V.2    Pace, P.F.3
  • 46
    • 77956793010 scopus 로고    scopus 로고
    • Inhaler costs and medication nonadherence among seniors with chronic pulmonary disease
    • Castaldi P.J., Rogers W.H., Safran D.G., et al. Inhaler costs and medication nonadherence among seniors with chronic pulmonary disease. Chest 2010, 138(3):614-620.
    • (2010) Chest , vol.138 , Issue.3 , pp. 614-620
    • Castaldi, P.J.1    Rogers, W.H.2    Safran, D.G.3
  • 47
    • 79958740350 scopus 로고    scopus 로고
    • Associations between prescription copayment levels and β-blocker medication adherence in commercially insured heart failure patients 50 years and older
    • Patterson M.E., Blalock S.J., Smith A.J., et al. Associations between prescription copayment levels and β-blocker medication adherence in commercially insured heart failure patients 50 years and older. Clin Ther 2011, 33(5):608-616.
    • (2011) Clin Ther , vol.33 , Issue.5 , pp. 608-616
    • Patterson, M.E.1    Blalock, S.J.2    Smith, A.J.3
  • 48
    • 33748785457 scopus 로고    scopus 로고
    • The effects of prescription drug copayments on statin adherence
    • Gibson T.B., Mark T.L., McGuigan K.A., et al. The effects of prescription drug copayments on statin adherence. Am J Manag Care 2006, 12(9):509-517.
    • (2006) Am J Manag Care , vol.12 , Issue.9 , pp. 509-517
    • Gibson, T.B.1    Mark, T.L.2    McGuigan, K.A.3
  • 49
    • 79959325702 scopus 로고    scopus 로고
    • Association between prescription co-payment amount and compliance with adjuvant hormonal therapy in women with early-stage breast cancer
    • Neugut A.I., Subar M., Wilde E.T., et al. Association between prescription co-payment amount and compliance with adjuvant hormonal therapy in women with early-stage breast cancer. J Clin Oncol 2011, 29(18):2534-2542.
    • (2011) J Clin Oncol , vol.29 , Issue.18 , pp. 2534-2542
    • Neugut, A.I.1    Subar, M.2    Wilde, E.T.3
  • 50
    • 47749091710 scopus 로고    scopus 로고
    • Barriers to medication adherence in poorly controlled diabetes mellitus
    • Odegard P.S., Gray S.L. Barriers to medication adherence in poorly controlled diabetes mellitus. Educ 2008, 34(4):692-697.
    • (2008) Educ , vol.34 , Issue.4 , pp. 692-697
    • Odegard, P.S.1    Gray, S.L.2
  • 51
    • 34250179723 scopus 로고    scopus 로고
    • Fixed-dose combinations improve medication compliance: a meta-analysis
    • Bangalore S., Kamalakkannan G., Parkar S., et al. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 2007, 120(8):713-719.
    • (2007) Am J Med , vol.120 , Issue.8 , pp. 713-719
    • Bangalore, S.1    Kamalakkannan, G.2    Parkar, S.3
  • 52
    • 67650651982 scopus 로고    scopus 로고
    • Improving outcomes in hypertensive patients: focus on adherence and persistence with antihypertensive therapy
    • Elliott W.J. Improving outcomes in hypertensive patients: focus on adherence and persistence with antihypertensive therapy. J Clin Hypertens (Greenwich) 2009, 11(7):376-382.
    • (2009) J Clin Hypertens (Greenwich) , vol.11 , Issue.7 , pp. 376-382
    • Elliott, W.J.1
  • 53
    • 80052961455 scopus 로고    scopus 로고
    • Factors associated with medication adherence in patients with chronic obstructive pulmonary disease
    • Agh T., Inotai A., Meszaros A. Factors associated with medication adherence in patients with chronic obstructive pulmonary disease. Respiration 2011, 82(4):328-334.
    • (2011) Respiration , vol.82 , Issue.4 , pp. 328-334
    • Agh, T.1    Inotai, A.2    Meszaros, A.3
  • 54
    • 79955912187 scopus 로고    scopus 로고
    • Association between patient beliefs and medication adherence following hospitalization for acute coronary syndrome
    • Allen LaPointe N.M., Ou F.S., Calvert S.B., et al. Association between patient beliefs and medication adherence following hospitalization for acute coronary syndrome. Am Heart J 2011, 161(5):855-863.
    • (2011) Am Heart J , vol.161 , Issue.5 , pp. 855-863
    • Allen LaPointe, N.M.1    Ou, F.S.2    Calvert, S.B.3
  • 55
    • 78751611384 scopus 로고    scopus 로고
    • Medication beliefs predict medication adherence in older adults with multiple illnesses
    • Schüz B., Marx C., Wurm S., et al. Medication beliefs predict medication adherence in older adults with multiple illnesses. J Psychosom Res 2011, 70(2):179-187.
    • (2011) J Psychosom Res , vol.70 , Issue.2 , pp. 179-187
    • Schüz, B.1    Marx, C.2    Wurm, S.3
  • 56
    • 79952498421 scopus 로고    scopus 로고
    • A review of diabetes treatment adherence and the association with clinical and economic outcomes
    • Asche C., LaFleur J., Conner C. A review of diabetes treatment adherence and the association with clinical and economic outcomes. Clin Ther 2011, 33(1):74-109.
    • (2011) Clin Ther , vol.33 , Issue.1 , pp. 74-109
    • Asche, C.1    LaFleur, J.2    Conner, C.3
  • 57
    • 79551600980 scopus 로고    scopus 로고
    • Medication persistence in the treatment of HIV infection: a review of the literature and implications for future clinical care and research
    • Bae J.W., Guyer W., Grimm K., et al. Medication persistence in the treatment of HIV infection: a review of the literature and implications for future clinical care and research. AIDS 2011, 25(3):279-290.
    • (2011) AIDS , vol.25 , Issue.3 , pp. 279-290
    • Bae, J.W.1    Guyer, W.2    Grimm, K.3
  • 58
    • 0036719562 scopus 로고    scopus 로고
    • Patient adherence and medical treatment outcomes: a meta-analysis
    • DiMatteo M.R., Giordani P.J., Lepper H.S., et al. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care 2002, 40(9):794-811.
    • (2002) Med Care , vol.40 , Issue.9 , pp. 794-811
    • DiMatteo, M.R.1    Giordani, P.J.2    Lepper, H.S.3
  • 59
    • 77957297196 scopus 로고    scopus 로고
    • American Society of Hypertension Writing Group. ASH position paper: adherence and persistence with taking medication to control high blood pressure
    • Hill M.N., Miller N.H., DeGeest S. American Society of Hypertension Writing Group. ASH position paper: adherence and persistence with taking medication to control high blood pressure. J Clin Hypertens (Greenwich) 2010, 12(10):757-764.
    • (2010) J Clin Hypertens (Greenwich) , vol.12 , Issue.10 , pp. 757-764
    • Hill, M.N.1    Miller, N.H.2    DeGeest, S.3
  • 60
    • 77957225819 scopus 로고    scopus 로고
    • Lifestyle and psychosocial risk factors predict non-adherence to medication
    • Aggarwal B., Mosca L. Lifestyle and psychosocial risk factors predict non-adherence to medication. Ann Behav Med 2010, 40(2):228-233.
    • (2010) Ann Behav Med , vol.40 , Issue.2 , pp. 228-233
    • Aggarwal, B.1    Mosca, L.2
  • 61
    • 66349097761 scopus 로고    scopus 로고
    • The clinical and economic burden of nonadherence with antihypertensive and lipid-lowering therapy in hypertensive patients
    • Cherry S.B., Benner J.S., Hussein M.A., et al. The clinical and economic burden of nonadherence with antihypertensive and lipid-lowering therapy in hypertensive patients. Value Health 2009, 12(4):489-497.
    • (2009) Value Health , vol.12 , Issue.4 , pp. 489-497
    • Cherry, S.B.1    Benner, J.S.2    Hussein, M.A.3
  • 62
    • 0022632510 scopus 로고
    • Concurrent and predictive validity of a self-reported measure of medication adherence
    • Morisky D.E., Green L.W., Levine D.M. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care 1986, 24(1):67-74.
    • (1986) Med Care , vol.24 , Issue.1 , pp. 67-74
    • Morisky, D.E.1    Green, L.W.2    Levine, D.M.3
  • 63
    • 79955942432 scopus 로고    scopus 로고
    • Selection of a validated scale for measuring medication adherence
    • Lavsa S.M., Holzworth A., Ansani N.T. Selection of a validated scale for measuring medication adherence. J Am Pharm Assoc (2003) 2011, 51(1):90-94.
    • (2011) J Am Pharm Assoc (2003) , vol.51 , Issue.1 , pp. 90-94
    • Lavsa, S.M.1    Holzworth, A.2    Ansani, N.T.3
  • 64
    • 49349115364 scopus 로고    scopus 로고
    • Predictive validity of a medication adherence measure for hypertension control
    • Morisky D.E., Ang A., Krousel-Wood M., et al. Predictive validity of a medication adherence measure for hypertension control. J Clin Hypertens 2008, 10(5):348-354.
    • (2008) J Clin Hypertens , vol.10 , Issue.5 , pp. 348-354
    • Morisky, D.E.1    Ang, A.2    Krousel-Wood, M.3
  • 65
    • 79957623430 scopus 로고    scopus 로고
    • Defining the minimal detectable change in scores on the eight-item Morisky Medication Adherence Scale
    • Muntner P., Joyce C., Holt E., et al. Defining the minimal detectable change in scores on the eight-item Morisky Medication Adherence Scale. Ann Pharmacother 2011, 45(5):569-575.
    • (2011) Ann Pharmacother , vol.45 , Issue.5 , pp. 569-575
    • Muntner, P.1    Joyce, C.2    Holt, E.3
  • 66
    • 47949124971 scopus 로고    scopus 로고
    • Development of the ASK-20 adherence barrier survey
    • Hahn S.R., Park J., Skinner E.P., et al. Development of the ASK-20 adherence barrier survey. Curr Med Res Opin 2008, 24(7):2127-2138.
    • (2008) Curr Med Res Opin , vol.24 , Issue.7 , pp. 2127-2138
    • Hahn, S.R.1    Park, J.2    Skinner, E.P.3
  • 67
    • 67649370680 scopus 로고    scopus 로고
    • Further testing of the reliability and validity of the ASK-20 adherence barrier questionnaire in a medical center outpatient population
    • Matza L.S., Yu-Isenberg K.S., Coyne K.S. Further testing of the reliability and validity of the ASK-20 adherence barrier questionnaire in a medical center outpatient population. Curr Med Res Opin 2008, 24(11):3197-3206.
    • (2008) Curr Med Res Opin , vol.24 , Issue.11 , pp. 3197-3206
    • Matza, L.S.1    Yu-Isenberg, K.S.2    Coyne, K.S.3
  • 68
    • 70449492021 scopus 로고    scopus 로고
    • Derivation and validation of the ASK-12 adherence barrier survey
    • Matza L.S., Park J., Coyne K.S., et al. Derivation and validation of the ASK-12 adherence barrier survey. Ann Pharmacother 2009, 43(10):1621-1630.
    • (2009) Ann Pharmacother , vol.43 , Issue.10 , pp. 1621-1630
    • Matza, L.S.1    Park, J.2    Coyne, K.S.3
  • 69
    • 79951900573 scopus 로고    scopus 로고
    • Strategies to improve medication adherence reported by diabetes patients and caregivers: results of a taking control of your diabetes survey
    • Morello C.M., Chynoweth M., Kim H., et al. Strategies to improve medication adherence reported by diabetes patients and caregivers: results of a taking control of your diabetes survey. Ann Pharmacother 2011, 45:145-153.
    • (2011) Ann Pharmacother , vol.45 , pp. 145-153
    • Morello, C.M.1    Chynoweth, M.2    Kim, H.3
  • 70
    • 77955982904 scopus 로고    scopus 로고
    • Comparative effectiveness research: evaluating pharmacist interventions and strategies to improve medication adherence
    • Carter B.L., Foppe van Mil J.W. Comparative effectiveness research: evaluating pharmacist interventions and strategies to improve medication adherence. Am J Hypertens 2010, 23(9):949-955.
    • (2010) Am J Hypertens , vol.23 , Issue.9 , pp. 949-955
    • Carter, B.L.1    Foppe van Mil, J.W.2
  • 71
    • 79955644501 scopus 로고    scopus 로고
    • Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: review and meta-analysis
    • Morgado M.P., Morgado S.R., Mendes L.C., et al. Pharmacist interventions to enhance blood pressure control and adherence to antihypertensive therapy: review and meta-analysis. Am J Health Syst Pharm 2011, 68(3):241-253.
    • (2011) Am J Health Syst Pharm , vol.68 , Issue.3 , pp. 241-253
    • Morgado, M.P.1    Morgado, S.R.2    Mendes, L.C.3
  • 72
    • 33845450660 scopus 로고    scopus 로고
    • Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial
    • Lee J.K., Grace K.A., Taylor A.J. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial. JAMA 2006, 296(21):2563-2571.
    • (2006) JAMA , vol.296 , Issue.21 , pp. 2563-2571
    • Lee, J.K.1    Grace, K.A.2    Taylor, A.J.3
  • 73
    • 84861131508 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011
    • Reports received and reports entered into AERS by year 2011, U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011. http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/ucm070434.htm.
    • (2011) Reports received and reports entered into AERS by year
  • 74
    • 84861130584 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011
    • AERS patient outcomes by year 2011, U.S. Food and Drug Administration, Available at:, Accessed August 15, 2011. http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/ucm070461.htm.
    • (2011) AERS patient outcomes by year
  • 75
    • 80052517354 scopus 로고    scopus 로고
    • Adverse drug events in U.S. adult ambulatory medical care
    • Sarkkar U., Lopez A., Maselli J.H., et al. Adverse drug events in U.S. adult ambulatory medical care. Health Serv Res 2011, 46(5):1517-1533.
    • (2011) Health Serv Res , vol.46 , Issue.5 , pp. 1517-1533
    • Sarkkar, U.1    Lopez, A.2    Maselli, J.H.3
  • 76
    • 0037420274 scopus 로고    scopus 로고
    • Incidence and preventability of adverse drug events among older persons in the ambulatory setting
    • Gurwitz J.H., Field T.S., Harrold L.R., et al. Incidence and preventability of adverse drug events among older persons in the ambulatory setting. JAMA 2003, 289(9):1107-1116.
    • (2003) JAMA , vol.289 , Issue.9 , pp. 1107-1116
    • Gurwitz, J.H.1    Field, T.S.2    Harrold, L.R.3
  • 77
    • 33646928882 scopus 로고    scopus 로고
    • Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay
    • Hanlon J.T., Pieper C.F., Hajjar E.R., et al. Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay. J Gerontol A Biol Sci Med Sci 2006, 61(5):511-515.
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , Issue.5 , pp. 511-515
    • Hanlon, J.T.1    Pieper, C.F.2    Hajjar, E.R.3
  • 78
    • 15744386347 scopus 로고    scopus 로고
    • Adverse drug reaction risk factors in older outpatients
    • Hajjar E.R., Hanlon J.T., Artz M.B., et al. Adverse drug reaction risk factors in older outpatients. Am J Geriatr Pharmacother 2003, 1(2):82-89.
    • (2003) Am J Geriatr Pharmacother , vol.1 , Issue.2 , pp. 82-89
    • Hajjar, E.R.1    Hanlon, J.T.2    Artz, M.B.3
  • 79
    • 3843146052 scopus 로고    scopus 로고
    • Risk factors for adverse drug events among older adults in the ambulatory setting
    • Field T.S., Gurwitz J.H., Harrold L.R., et al. Risk factors for adverse drug events among older adults in the ambulatory setting. J Am Geriatr Soc 2004, 52(8):1349-1354.
    • (2004) J Am Geriatr Soc , vol.52 , Issue.8 , pp. 1349-1354
    • Field, T.S.1    Gurwitz, J.H.2    Harrold, L.R.3
  • 81
    • 24044491590 scopus 로고    scopus 로고
    • Medication-related problems in the elderly
    • Simonson W., Feinberg J.L. Medication-related problems in the elderly. Drugs Aging 2005, 22(7):559-569.
    • (2005) Drugs Aging , vol.22 , Issue.7 , pp. 559-569
    • Simonson, W.1    Feinberg, J.L.2
  • 82
    • 0344395633 scopus 로고    scopus 로고
    • Principles of drug therapy for the elderly patient
    • Bressler R., Bahl J.J. Principles of drug therapy for the elderly patient. Mayo Clin Proc 2003, 78(12):1564-1577.
    • (2003) Mayo Clin Proc , vol.78 , Issue.12 , pp. 1564-1577
    • Bressler, R.1    Bahl, J.J.2
  • 83
    • 41549107131 scopus 로고    scopus 로고
    • The effect of computerized physician order entry with clinical decision support on the rates of adverse drug events: a systematic review
    • Wolfstadt J.I., Gurwitz J.H., Field T.S. The effect of computerized physician order entry with clinical decision support on the rates of adverse drug events: a systematic review. J Gen Intern Med 2008, 23(4):451-458.
    • (2008) J Gen Intern Med , vol.23 , Issue.4 , pp. 451-458
    • Wolfstadt, J.I.1    Gurwitz, J.H.2    Field, T.S.3
  • 84
    • 84861118941 scopus 로고    scopus 로고
    • Healthpeople.gov, Available at:, Accessed August 15, 2011
    • Medical product safety 2011, Healthpeople.gov, Available at:, Accessed August 15, 2011. http://www.healthypeople.gov/2020/topicsobjectives2020/overview.aspx%3Ftopicid%3D27.
    • (2011) Medical product safety


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