Barriers to and Determinants of Medication Adherence in Hypertension Management: Perspective of the Cohort Study of Medication Adherence Among Older Adults

Medical Clinics of North America

Volumn 93, Issue 3, 2009, Pages 753-769

  Krousel Wood, Marie A ^a,b,c   Muntner, Paul ^d   Islam, Tareq ^b   Morisky, Donald E ^e   Webber, Larry S ^b  

^a OCHSNER CLINIC FOUNDATION   (United States)

^b TULANE UNIVERSITY   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Barriers; Blood pressure control; Cohort; Hypertension; Medication adherence; Morisky scale; Older adults; Pharmacy fill adherence

Indexed keywords

AGE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RISK; HUMAN; HYPERTENSION; PATIENT COMPLIANCE; PREVALENCE; PRIORITY JOURNAL; QUALITY CONTROL; RACE DIFFERENCE; REVIEW; SEX DIFFERENCE; SOCIAL ASPECT; STAFF TRAINING;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIHYPERTENSIVE AGENTS; COHORT STUDIES; CONTINENTAL POPULATION GROUPS; DATA COLLECTION; FEMALE; HEALTH SERVICES ACCESSIBILITY; HEALTH SERVICES NEEDS AND DEMAND; HUMANS; HYPERTENSION; MALE; MEDICATION ADHERENCE; RISK FACTORS;

EID: 65449169135     PISSN: 00257125     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcna.2009.02.007     Document Type: Review

References (80)

1. Chobanian A.V., Bakris G.L., Black H.R., et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. JAMA 289 (2003) 2560-2572
2. Krousel-Wood M., Thomas S., Muntner P., et al. Medication adherence: a key factor in achieving blood pressure control and good clinical outcomes in hypertensive patients. Curr Opin Cardiol 19 (2004) 357-362
3. Ong K.L., Cheung B.M., Man Y.B., et al. Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004. Hypertension 49 (2007) 69-75
4. Hamilton G.A. Measuring adherence in a hypertension clinic trial. Eur J Cardiovasc Nurs 2 (2003) 219-228
5. Dusing R. Overcoming barriers to effective blood pressure control in patients with hypertension. Curr Med Res Opin 22 8 (2006) 1545-1553
6. Borzecki A.M., Oliveria S.A., and Berlowitz D.R. Barriers to hypertension control. Am Heart J 149 (2005) 785-794
7. Osterberg L., and Blaschke T. Adherence to medication. N Engl J Med 353 (2005) 487-497
8. Callahan C.M., Unverzaqt F.W., Hui S.L., et al. Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care 40 (2002) 771-781
9. Stanley E., Wood R.F., Kergosien L., et al. A comparison of self reported versus administrative race data. [abstract]. J Investig Med 56 (2008) 485
10. Morisky D.E., Ang A., Krousel-Wood M.A., et al. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens 10 (2008) 348-354
11. Krousel-Wood M.A., Islam T., Webber L.S., et al. New medication adherence scale versus pharmacy fill rates in hypertensive seniors. Am J Managed Care 15 (2009) 59-66
12. Kopjar B., Sales A.E.B., Pineros S.L., et al. Adherence with statin therapy in secondary prevention of coronary heart disease in veterans administration male population. Am J Cardiol 92 (2003) 1106-1108
13. Rizzo J.A., and Simons W.R. Variations in compliance among hypertensive patients by drug class: implications for health care costs. Clin Ther 19 (1997) 1446-1457
14. Sikka R., Xia F., and Aubert R.E. Estimating medication persistency using administrative claims data. Am J Manag Care 11 (2005) 449-457
15. Simpson E., Beck C., Richard H., et al. Drug prescriptions after acute myocardial infarction: dosage, compliance, and persistence. Am Heart J 145 (2003) 438-444
16. Charlson M.E., Pompei P., Ales K.L., et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40 (1987) 373-383
17. Deyo R.A., Cherkin D.C., and Ciol M.A. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 45 (1992) 613-619
18. Russell C., Conn V., and Jantarakupt P. Older adult medication compliance: integrated review of randomized controlled trials. Am J Health Behav 30 (2006) 636-650
19. Fongwa M.N., Evangelista L.S., Hays R.D., et al. Adherence treatment factors in hypertensive African American women. Vasc Health Risk Manag 4 1 (2008) 157-166
20. Ogedegbe G., Mancuso C.A., Allegrante J.P., et al. Development and evaluation of a medication adherence self-efficacy scale in hypertensive African-American patients. J Clin Epidemiol 56 (2003) 520-529
21. Ogedegbe G., Harrison M., Robbins L., et al. Barriers and facilitators of medication adherence in hypertensive African Americans: a qualitative study. Ethn Dis 14 (2004) 3-12
22. Harmon G., Lefante J., and Krousel-Wood M.A. The role of providers in improving patient adherence to antihypertensive medications. Curr Opin Cardiol 21 (2006) 310-315
23. Hawkshead J., and Krousel-Wood M.A. Techniques for measuring medication adherence in hypertensive patients in outpatient settings: advantages and limitations. Dis Manage Health Outcomes 15 (2007) 109-118
24. Krousel-Wood M., Hyre A., Muntner P., et al. Methods to improve medication adherence in hypertensive patients: current status and future directions. Curr Opin Cardiol 20 (2005) 296-300
25. Marentette M.A., Gerth W.C., Billings D.K., et al. Antihypertensive persistence and drug class. Can J Cardiol 18 (2002) 649-656
26. Monane M., Bohn R.L., Gurwitz J.H., et al. The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly. Am J Hypertens 10 (1997) 697-704
27. Caro J.J., Salas M., Speckman J.L., et al. Persistence with treatment for hypertension in actual practice. CMAJ 160 (1999) 31-37
28. Hyre A., Krousel-Wood M.A., Muntner P., et al. Prevalence and predictors of poor antihypertensive medication adherence in an urban health clinic setting. J Clin Hypertens 9 (2007) 179-186
29. Sharkness C.M., and Snow D.A. The patient's view of hypertension and compliance. Am J Prev Med 8 (1992) 141-146
30. Wang P.S., Bohn R.L., Knight E., et al. Noncompliance with antihypertensive medications: the impact of depressive symptoms and psychosocial factors. J Gen Intern Med 17 (2002) 504-511
31. Wang P.S., Avorn J., Brookhart M.A., et al. Effects of noncardiovascular comorbidites on antihypertensive use in elderly hypertensives. Hypertension 46 (2005) 273-279
32. Egan B.H., Lackland D.T., and Cutler N.E. Awareness, knowledge and attitudes of older Americans about high blood pressure: implications for health care policy, education, and research. Arch Intern Med 163 (2003) 681-687
33. Iskedjian M., Einarson T.R., MacKeigan L.D., et al. Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: evidence from meta-analysis. Clin Ther 24 (2002) 302-316
34. Brown C.M., and Segal R. The effects of health and treatment perceptions on the use of prescribed medication and home remedies among African American and white American hypertensives. Soc Sci Med 43 (1996) 903-917
35. Steinman M.A., Sands L.P., and Covinsky K.E. Self-retriction of medications due to cost in seniors without prescription coverage: a national survey. J Gen Intern Med 16 (2001) 793-799
36. Gohar F., Greenfield S.M., Beevers D.G., et al. Self-care and adherence to medication: a survey in the hypertension outpatient clinic. BMC Complement Altern Med 8 (2008) 4
37. World Health Organization. Hypertension in adherence to long-term therapies evidence for action (2003), World Health Organization, Geneva Switzerland p. 107-14
38. Grimm R.H., Grandits G.A., Prineas R.J., et al. Long-term effects on sexual function of five antihypertensive drugs and nutritional hygenic treatment in hypertensive men and women. Treatment of Mild Hypertension Study. Hypertension 29 (1997) 8-14
39. Wassertheil-Smoller S., Blaufox M.D., Oberman A., et al. Effects of antihypertensives on sexual function and quality of life: the TAIM study. Ann Intern Med 114 (1991) 613-620
40. Gregoire J.P., Moisan J., Guibert R., et al. Tolerability of antihypertensive drugs in a community-based setting. Clin Ther 23 (2001) 715-726
41. Morisky D.E., Green W., Levine D.M., et al. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care 24 (1986) 67-74
42. Schroeder K., Fahey T., Hollinghurst S., et al. Nurse-led adherence support in hypertension: a randomized controlled trial. Fam Pract 22 (2005) 144-151
43. Islam T., Muntner P., Webber L.S., et al. Cohort study of medication adherence in older adults: extended effects of Hurricane Katrina on medication adherence among older adults. Am J Med Sci 336 2 (2008) 105-110
44. Krousel-Wood M., Islam T., Muntner P., et al. Medication adherence in older patients with hypertension after Hurricane Katrina: implications for clinical practice and disaster management. Am J Med Sci 336 (2008) 99-104
45. McDonald H.P., Garg A.X., and Haynes R.B. Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA 288 22 (2002) 2868-2879
46. Morrison A., Wertheimer A., and Berger M. Interventions to improve antihypertensive drug adherence: a quantitative review of trials. Formulary 35 (2000) 234-255
47. Roter D.L., Hall J.A., Merisca R., et al. Effectiveness of interventions to improve patient compliance: a meta-analysis. Med Care 36 8 (1998) 1138-1161
48. Schroeder K., Fahey T., and Ebrahim S. How can we improve adherence to blood pressure-lowering medication in ambulatory care? Systematic review of randomized controlled trials. Arch Intern Med 164 7 (2004) 722-732
49. Takiya L.N., Peterson A.M., and Finley R.S. Meta-analysis of interventions for medication adherence to antihypertensives. Ann Pharmacother 38 10 (2004) 1617-1624
50. Wetzels G.E., Nelemans P., Schouten J.S., et al. Facts and fiction of poor compliance as a cause of inadequate blood pressure control: a systematic review. J Hypertens 22 10 (2004) 1849-1855
51. Inui T.S., Yourtee E.L., and Williamson J.W. Improved outcomes in hypertension after physician tutorials: a controlled trial. Ann Intern Med 84 (1976) 646-651
52. Bokhour B.G., Belowitz D.R., Long J.A., et al. How do providers assess antihypertensive medication adherence in medical encounters?. J Gen Intern Med 21 (2006) 577-583
53. Grymonpre R., Cheang M., Fraser M., et al. Validity of a prescription claims database to estimate medication adherence in older persons. Med Care 44 (2006) 471-477
54. Jones D.W., Appel L.J., Sheps S.G., et al. Measuring blood pressure accurately. New and persistent challenges. JAMA 289 (2003) 1027-1030
55. Elder N.C., and Hickner J. Missing clinical information. The system is down. JAMA 293 (2005) 617-619
56. Sherbourne C.D., and Stewart A.L. The MOS social support survey. Soc Sci Med 32 (1991) 705-714
57. Williams M.V., Baker D.W., Parker R.M., et al. Relationship of functional health literacy to patients' knowledge of their chronic disease: a study of patients with hypertension and diabetes. Arch Intern Med 158 (1998) 166-172
58. Labbate L.A., and Lare S.B. Sexual dysfunction in male psychiatric outpatients: validity of the Massachusetts General Hospital Sexual Functioning Questionnaire. Psychother Psychosom 70 (2001) 221-225
59. Kim M.T., Han H.R., Hill M.N., et al. Depression, substance use, adherence behaviors, and blood pressure in urban hypertensive black men. Ann Behav Med 26 (2003) 24-31
60. Knight R.G., Williams S., McGee R., et al. Psychometric properties of the Center for Epidemiologic Studies Depression Scale (CES-D) in a sample of women in middle life. Behav Res Ther 35 (1997) 373-380
61. Radloff L.S. The CES-D scale: a self-report depression scale for research in the general population. Applied Psychological Measurement 1 (1977) 385-401
62. Roberts R.E., Vernon S.W., and Rhoades H.M. Effests of language and ethnic status on reliability and validity of the CES-D with psychiatric patients. J Nerv Ment Dis 177 (1989) 581-592
63. Fernander A., Duran R., Saab P., et al. Assessing the reliability and validity of the John Henry Scale in an urban sample of African-Americans and white-Americans. Ethn Health 8 (2003) 147-161
64. Cohen S., Kamarck T., and Mermelstein R. A global measure of perceived stress. J Health Soc Behav 24 (1983) 385-396
65. 2003-04 Blood Pressure Questionnaire-BPQ_C. Available at:. http://www.cdc.gov/nchs/data/nhanes/nhanes_03_04/sp_bpq_c.pdf Accessed February 15, 2008
66. Lengacher C., Bennett M.P., Kipp K.E., et al. Design and testing of the use of a complementary and alternative therapies survey in women with breast cancer. Oncol Nurs Forum 30 (2003) 811-821
67. Davies A.R., and Ware J.E. GHAA's Consumer Satisfaction Survey and User's Manual. 2nd edition (1991), Group Health Association of America, Inc., Washington, DC p. 1-48
68. Jatulis D.E., Bundek N.I., and Legorreta A.P. Identifying predictors of satisfaction with access to medical care and quality of care. Am J Med Qual 12 (1997) 11-18
69. Krousel-Wood M.A., Re R., Abdoh A., et al. Patient and physician satisfaction in a clinical study of telemedicine in a hypertensive patient population. J Telemed Telecare 7 (2001) 206-211
70. Meng Y.Y., Jatulis D.E., McDonald J.P., et al. Satisfaction with access to and quality of health care among Medicare enrollees in a health maintenance organization. West J Med 166 (1997) 242-247
71. Holmes T.H., and Rahe R.H. The social readjustment rating scale. J Psychosom Res 11 (1967) 213-218
72. Inui A., Kitaoaka H., Majima M., et al. Effects of the Kobe Earthquake on stress and glycemic control in patients with diabetes mellitus. Arch Intern Med 158 (1998) 274-278
73. Benight C., Ironson G., and Durham R. Psychometric properties of a hurricane coping self-efficacy measure. J Trauma Stress 12 (1999) 379-386
74. Ruggiero K.J., Del Ben K., Scotti J.R., et al. Psychometric properties of the PTSD checklist-civilian version. J Trauma Stress 16 (2003) 495-502
75. Weathers FW, Huska JA, Keane TM. PCL-C for DSM-IV Boston: National Center for PTSD-Behavioral Division; 1991.
76. Bland S.H., Parinaro E., Krogh V., et al. Long term relations between earthquake experiences and coronary heart disease risk factors. Am J Epidemiol 151 (2000) 1086-1090
77. Krousel-Wood M.A., and Re R.N. Health status assessment in a hypertension section of an internal medicine clinic. Am J Med Sci 308 (1994) 211-217
78. McHorney C.A., Ware J.E., Rogers W., et al. The validity and relative precision of MOS short-and long-form health scales and Dartmouth COOP chart. Results from the Medical Outcomes Study. Med Care 30 (1992) MS253-MS265
79. Ware J.E., and Sherbourne C.D. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med Care 30 (1992) 473-483
80. Ware J.E., Snow K.K., Kosinski M., et al. SF-36 Health survey-manual and interpretation guide (1993), New England Medical Center, Boston