Inappropriate medication use as a risk factor for Self-reported adverse drug effects in older adults

Journal of the American Geriatrics Society

Volumn 57, Issue 6, 2009, Pages 1000-1006

  Chrischilles, Elizabeth A ^a   Vangilder, Rachel ^b   Wright, Kara ^a   Kelly, Michael ^a   Wallace, Robert B ^a  

^a UNIVERSITY OF IOWA   (United States)

^b Wellmark Blue Cross Blue Shield   (United States)

Author keywords

Adverse drug effects; Medicare; Medication

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DEXTROPROPOXYPHENE;

ADVERSE DRUG REACTION; AGED; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG INTERACTION; DRUG UTILIZATION; FEMALE; FOLLOW UP; GASTROINTESTINAL DISEASE; HEALTH SURVEY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICARE; RISK FACTOR; SELF REPORT; WALKING DIFFICULTY;

AGED; AGED, 80 AND OVER; COHORT STUDIES; DRUG INTERACTIONS; FEMALE; HUMANS; MALE; MEDICATION ERRORS; PHARMACEUTICAL PREPARATIONS; POSTAL SERVICE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 66549125080     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2009.02269.x     Document Type: Article

References (32)

1. Kohn LT, Corrigan JM, Donaldson MS, editors, Committee on Quality of Healthcare in America, Institute of Medicine. To Err Is Human. Building a Safer Health System. Washington, DC : National Academy Press, 2000.
2. Field TS, Gurwitz JH, Harrold LR et al. Risk factors for adverse drug events among older adults in the ambulatory setting. J Am Geriatr Soc 2004 52 : 1349 1354. (Pubitemid 39038210)
3. Mannesse CK, Derkx FHM, deRidder MAJ et al. Contribution of adverse drug reactions to hospital admission of older patients. Age Ageing 2000 29 : 35 39. (Pubitemid 30055061)
4. Onder G, Pedone C, Landi F et al. Adverse drug reactions as cause of hospital admissions: Results from the Italian group of pharmacoepidemiology in the elderly (GIFA). J Am Geriatr Soc 2002 50 : 1962 1968. (Pubitemid 35462441)
5. Gandhi TK, Burstin HR, Cook EF et al. Drug complications in outpatients. J Gen Intern Med 2000 15 : 149 154. (Pubitemid 30155346)
6. Beard K. Adverse reactions as a cause of hospital admission in the aged. Drugs Aging 1992 2 : 356 367.
7. Routledge PA, O'Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol 2004 57 : 121 126. (Pubitemid 38223523)
8. Atkin PA, Veitch PC, Veitch EM et al. The epidemiology of serious adverse drug reactions among the elderly. Drugs Aging 1999 2 : 141 152. (Pubitemid 29086114)
9. Laroche ML, Charmes JP, Nouaille Y et al. Is inappropriate medication use a major cause of adverse drug reactions in the elderly? Br J Clin Pharmacol 2007 63 : 177 186. (Pubitemid 46072104)
10. Onder G, Landi F, Liperoti R et al. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol 2005 61 : 453 459. (Pubitemid 41569324)
11. Chang CM, Liu PY, Yang YH et al. Use of the Beers criteria to predict adverse drug reactions among first-visit elderly outpatients. Pharmacotherapy 2005 25 : 831 838.
12. Rask KJ, Wells KJ, Teitel GS et al. Can an algorithm for appropriate prescribing predict adverse drug events? Am J Manage Care 2005 11 : 145 151. (Pubitemid 40387637)
13. Page RL, Ruscin JM. The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use. Am J Geriatr Pharmacother 2006 4 : 297 305.
14. Passarelli MC, Jacob-Filho W, Figueras A. Adverse drug reactions in an elderly hospitalised population: Inappropriate prescription is a leading cause. Drugs Aging 2005 22 : 767 777.
15. Budnitz DS, Shehab N, Kegler SR et al. Medication use leading to emergency department visits for adverse drug events in older adults. Ann Intern Med 2007 147 : 755 665.
16. Spinewine A, Schmader KE, Barber N et al. Appropriate prescribing in elderly people: How well can it be measured and optimized? Lancet 2007 370 : 173 184. (Pubitemid 47049724)
17. Beers MH, Ouslander JG, Rollingher I et al. Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med 1991 151 : 1825 1832.
18. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 1997 157 : 1531 1536. (Pubitemid 27305197)
19. Fick DM, Cooper JW, Wade WE et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: Results of a US consensus panel of experts. Arch Intern Med 2003 163 : 2716 2724. (Pubitemid 37517412)
20. McLeod PJ, Huang AR, Tamblyn RM et al. Defining inappropriate practices in prescribing for elderly people: A national consensus panel. Can Med Assoc J 1997 156 : 385 391. (Pubitemid 27078035)
21. Chrischilles E, Rubenstein L, VanGlider R et al. Risk factors for adverse drug events in older adults with mobility limitations in the community setting. J Am Geriatr Soc 2007 55 : 29 34. (Pubitemid 46046225)
22. Klabunde CN, Potosky AL, Legler JM et al. Development of a comorbidity index using physician claims data. J Clin Epidemiol 2000 53 : 1258 1267. (Pubitemid 32007842)
23. Chrischilles EA, Segar ET, Wallace RB. Self-reported adverse drug reactions and related resource use. A study of community-dwelling persons 65 years of age and older. Ann Intern Med 1992 117 : 634 640.
24. VanGilder R. Implementing the Beers Medication Appropriateness Measures in a Linked Database of Surveys, Dispensing Records, and Medicare Claims. University of Iowa College of Public Health Technical Report # 08-01 [on-line]. Available at Accessed August 29, 2008.
25. Hansten PD, Horn JR. Hansten and Horn's Managing Clinically Important Drug Interactions. Vancouver, WA : Applied Therapeutics Inc, 1998.
26. Fitzgerald LS, Hanlon JT, Shelton PS et al. Reliability of a modified medication appropriateness index in ambulatory older persons. Ann Pharmacother 1997 31 : 543 548. (Pubitemid 27203949)
27. Aspden P, Wolcott J, Bootman JL et al., (Editors) Preventing Medication Errors. Washington, DC : National Academy Press, 2006.
28. Steinman MA, Landefeld CS, Rosenthal GE et al. Polypharmacy and prescribing quality in older people. J Am Geriatr Soc 2006 54 : 1516 1523. (Pubitemid 44564145)
29. Kuijpers MAJ, van Marum RJ, Egberts ACG et al. Relationship between polypharmacy and underprescribing. Br J Clin Pharmacol 2008 65 : 130 133. (Pubitemid 350265160)
30. Wenger NS, Shekelle PG. Assessing care of vulnerable elders: ACOVE project overview. Ann Intern Med 2001 135 : 642 646. (Pubitemid 33015477)
31. Malone DC, Abarca J, Hansten PD et al. Identification of serious drug-drug interactions: Results of the partnership to prevent drug-drug interactions. J Am Pharm Assoc 2004 44 : 142 151.
32. Lindblad CI, Hanlon JT, Gross CR et al. Clinically important drug-disease interactions and their prevalence in older adults. Clin Therap 2006 28 : 1133 1143. (Pubitemid 44374751)