Comparison of 64cu-complexing bifunctional chelators for radioimmunoconjugation: Labeling efficiency, specific activity, and in vitro / in vivo stability

Bioconjugate Chemistry

Volumn 23, Issue 5, 2012, Pages 1029-1039

  Cooper, Maggie S ^a   Ma, Michelle T ^b   Sunassee, Kavitha ^a   Shaw, Karen P ^a   Williams, Jennifer D ^a   Paul, Rowena L ^a   Donnelly, Paul S ^b   Blower, Philip J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BODY FLUIDS; CHELATION; CHEMICAL BONDS; MOLECULES; STABILITY;

BI-FUNCTIONAL; CONDITION; HIGH SPECIFIC ACTIVITIES; IMMUNOCONJUGATE; IN-VITRO; IN-VIVO; LABELING EFFICIENCIES; MACROCYCLICS; RADIOIMMUNOCONJUGATES; RADIOLABELLING;

EFFICIENCY;

CHELATING AGENT; COPPER 64; PENTETIC ACID DERIVATIVE; RITUXIMAB; SARCOPHAGINE; TETRAXETAN; THIOUREA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG STABILITY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOLECULAR IMAGING; MOUSE; NONHUMAN; SERUM;

MUS;

ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHELATING AGENTS; COPPER RADIOISOTOPES; DRUG STABILITY; FEMALE; IMMUNOCONJUGATES; ISOTOPE LABELING; MACROCYCLIC COMPOUNDS; MICE; MICE, INBRED BALB C; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 84861166770     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300037w     Document Type: Article

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