Conjugation of chelating agents to proteins and radiolabeling with trivalent metallic isotopes

Nature Protocols

Volumn 1, Issue 1, 2006, Pages 314-317

  Cooper, Maggie S ^a   Sabbah, Emmanuelle M ^a   Mather, Stephen J ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; METAL; PROTEIN; RADIOISOTOPE;

ARTICLE; CHEMISTRY; ISOTOPE LABELING; METHODOLOGY;

CHELATING AGENTS; ISOTOPE LABELING; METALS; PROTEINS; RADIOISOTOPES;

EID: 33947365801     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2006.49     Document Type: Article

References (3)

1. Ginj, M. & Maecke, H.R. Radiometallo-labeled peptides in tumor diagnosis and therapy. Met. Ions Biol. Syst. 42, 109-142 (2004).
2. Mather, S. Radiolabelling of monoclonal antibodies. in Monoclonal Antibodies: A Practical Approach (P. Shepherd & C. Dean, eds.) 207-236 (Oxford University Press, Oxford, UK, 2000).
3. Meares, C.F. et al. Conjugation of antibodies with bifunctional chelating agents: Isothiocyanate and bromoacetamide reagents, methods of analysis and subsequent addition of metal ions. Anal. Biochem. 142, 68-78 (1984).