Serpin B1 protects colonic epithelial cell via blockage of neutrophil elastase activity and its expression is enhanced in patients with ulcerative colitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 10, 2012, Pages

  Uchiyama, Kazuhiko ^a   Naito, Yuji ^a   Takagi, Tomohisa ^a   Mizushima, Katsura ^a   Hirai, Yasuko ^a   Hayashi, Natsuko ^a   Harusato, Akihito ^a   Inoue, Ken ^a   Fukumoto, Kohei ^a   Yamada, Shinya ^a   Handa, Osamu ^a   Ishikawa, Takeshi ^a   Yagi, Nobuaki ^a   Kokura, Satoshi ^a   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Inflammatory bowel disease

Indexed keywords

DEXTRAN SULFATE; HYDROGEN PEROXIDE; LEUKOCYTE ELASTASE; MESSENGER RNA; SERINE PROTEINASE INHIBITOR; SERPIN B1; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CROHN DISEASE; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ULCERATIVE COLITIS; WESTERN BLOTTING;

ADULT; ANIMALS; CELL LINE; COLITIS, ULCERATIVE; COLON; FEMALE; HUMANS; HYDROGEN PEROXIDE; INTESTINAL MUCOSA; LEUKOCYTE ELASTASE; MALE; MICE; MIDDLE AGED; SERPINS; UP-REGULATION;

EID: 84861164282     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00292.2011     Document Type: Article

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