Intra-ophthalmic artery chemotherapy triggers vascular toxicity through endothelial cell inflammation and leukostasis

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 4, 2012, Pages 2439-2445

  Steinle, Jena J ^a   Zhang, Qiuhua ^a   Thompson, Karin Emmons ^a   Toutounchian, Jordan ^a   Ryan Yates, C ^a   Soderland, Carl ^b   Wang, Fan ^c   Stewart, Clinton F ^c   Haik, Barrett G ^a,c   Scott Williams, J ^a   Scott Jackson, J ^a   Mandrell, Timothy D ^a   Johnson, Dianna ^a   Wilson, Matthew W ^a,c  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Cell Systems Corporation   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MELPHALAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL ADHESION; CELL DEATH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOSTASIS; MACACCA MULATTA; MALE; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPHTHALMIC ARTERY; PRIORITY JOURNAL; RETINA; RETINA BLOOD VESSEL OCCLUSION; RETINOBLASTOMA; SUPER SELECTIVE INTRA OPHTHALMIC ARTERY CHEMOTHERAPY; TOXICITY; VASCULAR ENDOTHELIUM; VASCULAR TOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CARBOPLATIN; ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; MACACA MULATTA; MELPHALAN; NEUTROPHILS; OPHTHALMIC ARTERY; RNA, MESSENGER;

EID: 84861158349     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9466     Document Type: Article

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