Analytical characterization of an orally-delivered peptide pharmaceutical product

Analytical Chemistry

Volumn 84, Issue 10, 2012, Pages 4357-4372

  Kelley, Wayne P ^a   Chen, Shujun ^a   Floyd, Philip D ^a   Hu, Ping ^a   Kapsi, Shiva G ^a   Kord, Alireza S ^a   Sun, Mingjiang ^a   Vogt, Frederick G ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; ANALYSIS AND CHARACTERIZATION; ANALYTICAL CHARACTERIZATION; ANALYTICAL METHOD; DEGRADATION PRODUCTS; DRUG DELIVERY SYSTEM; ENTERIC-COATING; HIGH RESOLUTION MASS SPECTROMETRY; MULTI-DISCIPLINARY APPROACH; NON DESTRUCTIVE; PARATHYROID HORMONES; PEPTIDE PRODUCTS; PHARMACEUTICAL PRODUCTS; RAMAN MAPPING; RAMAN MICROSCOPY; SECONDARY STRUCTURES; SMALL-MOLECULE DRUGS; SOLID STATE NMR; SPECTROSCOPIC METHOD;

COATINGS; DEGRADATION; DRUG DELIVERY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; SPECTROSCOPIC ANALYSIS; SPHERES; SUGAR (SUCROSE);

CHARACTERIZATION;

PARATHYROID HORMONE; PEPTIDE; RECOMBINANT PROTEIN; SUCROSE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG FORMULATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORAL DRUG ADMINISTRATION; PROTEIN SECONDARY STRUCTURE; RAMAN SPECTROMETRY;

ADMINISTRATION, ORAL; AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMPOUNDING; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PARATHYROID HORMONE; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS, RAMAN; SUCROSE;

EID: 84861150397     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac203478r     Document Type: Article

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