Considerations on methylmercury (MeHg) treatments in in vitro studies

NeuroToxicology

Volumn 33, Issue 3, 2012, Pages 512-513

  Aschner, Michael ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DRINKING WATER; MERCURY; METHYLMERCURY;

ANIMAL BEHAVIOR; ASTROCYTE; BEHAVIOR CHANGE; BRAIN CORTEX; BRAIN LEVEL; CELL LEVEL; CELL SIZE; CELL STRUCTURE; CEREBELLUM; COGNITION; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; LONG TERM EXPOSURE; MATHEMATICAL ANALYSIS; NERVE CELL CULTURE; NEUROANATOMY; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; NOTE; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT;

ANIMALS; ASTROCYTES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; RISK ASSESSMENT;

EID: 84861148678     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.05.002     Document Type: Note

References (14)

1. Burbacher T.M., Rodier P.M., Weiss B. Methylmercury developmental neurotoxicity: a comparison of effects in humans and animals. Neurotoxicol Teratol 1990, 12:191-202.
2. Castoldi A.F., Onishchenko N., Johansson C., Coccini T., Roda E., Vahter M., et al. Neurodevelopmental toxicity of methylmercury: laboratory animal data and their contribution to human risk assessment. Regul Toxicol Pharmacol 2008, 51:215-229.
3. Choi B.H., Lapham L.W., Amin-Zaki L., Saleem T. Abnormal neuronal migration, deranged cerebral cortical organization, and diffuse white matter astrocytosis of human fetal brain: a major effect of methylmercury poisoning in utero. J Neuropathol Exp Neurol 1978, 37:719-733.
4. Fujimura M., Usuki F., Sawada M., Takashima A. Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain. Neurotoxicology 2009, 30:1000-1007.
5. Lapham L.W., Cernichiari E., Cox C., Myers G.J., Baggs R.B., Brewer R., et al. An analysis of autopsy brain tissue from infants prenatally exposed to methymercury. Neurotoxicology 1995, 16:689-704.
6. Lewandowski T.A., Ponce R.A., Charleston J.S., Hong S., Faustman E.M. Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment. Toxicol Sci 2003, 75:124-133.
7. Matthews B.W. Determination of molecular weight from protein crystals. J Mol Biol 1974, 82:513-526.
8. Newland M.C., Rasmussen E.B. Aging unmasks adverse effects of gestational exposure to methylmercury in rats. Neurotoxicol Teratol 2000, 22:819-828.
9. Newland M.C., Reed M.N., LeBlanc A., Donlin W.D. Brain and blood mercury and selenium after chronic and developmental exposure to methylmercury. Neurotoxicology 2006, 27:710-720.
10. Sager P.R., Aschner M., Rodier P.M. Persistent, differential alterations in developing cerebellar cortex of male and female mice after methylmercury exposure. Brain Res 1984, 314:1-11.
11. Shapiro A.M., Chan H.M. Characterization of demethylation of methylmercury in cultured astrocytes. Chemosphere 2008, 74:112-118.
12. Takeuchi T. Human effects of methylmercury as an environmental neurotoxicant. Neurotoxicology 1985, 345-367. Marcel Dekker, New York. K. Blum, L. Manzo (Eds.).
13. Takizawa Y. Mercury content in recognized patients and non-recognized patients exposed to methylmercury from Minamata Bay in the last ten years. Recent advances in minamata disease studies 1986, 1-39. Kodansha Ltd., Tokyo. T. Tsubaki, H. Takahashi (Eds.).
14. Toyama T., Shinkai Y., Yasutake A., Uchida K., Yamamoto M., Kumagai Y. Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury. Environ Health Perspect 2011, 119:1117-1122.