메뉴 건너뛰기




Volumn 13, Issue 7, 2012, Pages 477-486

p63 expression correlates with sensitivity to the Eg5 inhibitor AZD4877 in bladder cancer cells

Author keywords

Np63; Apoptosis; C myc; Gene expression profiling

Indexed keywords

ANTIMITOTIC AGENT; AZD 4877; CISPLATIN; DOCETAXEL; GEMCITABINE; KINESIN 5; MYC PROTEIN; PROTEIN P63; UNCLASSIFIED DRUG;

EID: 84861147306     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.19590     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • PMID:20610543
    • Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010; 60:277-300; PMID:20610543; http://dx.doi.org/10.3322/caac.20073.
    • (2010) CA Cancer J Clin , vol.60 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3    Ward, E.4
  • 3
    • 31444453665 scopus 로고    scopus 로고
    • The role of taxanes in the management of bladder cancer
    • PMID:16314289
    • Galsky MD. The role of taxanes in the management of bladder cancer. Oncologist 2005; 10:792-8; PMID:16314289; http://dx.doi.org/10.1634/ theoncologist. 10-10-792.
    • (2005) Oncologist , vol.10 , pp. 792-798
    • Galsky, M.D.1
  • 4
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • PMID:15057285
    • Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004; 4:253-65; PMID:15057285; http://dx.doi.org/10.1038/nrc1317.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 5
    • 34547136704 scopus 로고    scopus 로고
    • Targeting mitosis for anti-cancer therapy
    • PMID:17628120
    • Sudakin V, Yen TJ. Targeting mitosis for anti-cancer therapy. BioDrugs 2007; 21:225-33; PMID:17628120; http://dx.doi.org/10.2165/00063030-200721040- 00003.
    • (2007) BioDrugs , vol.21 , pp. 225-233
    • Sudakin, V.1    Yen, T.J.2
  • 6
    • 0036158822 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathy
    • PMID:11954874
    • Quasthoff S, Hartung HP. Chemotherapy-induced peripheral neuropathy. J Neurol 2002; 249:9- 17; PMID:11954874; http://dx.doi.org/10.1007/ PL00007853.
    • (2002) J Neurol , vol.249 , pp. 9-17
    • Quasthoff, S.1    Hartung, H.P.2
  • 7
    • 52749097817 scopus 로고    scopus 로고
    • Progress on kinesin spindle protein inhibitors as anti-cancer agents
    • PMID:18690830
    • Zhang Y, Xu W. Progress on kinesin spindle protein inhibitors as anti-cancer agents. Anticancer Agents Med Chem 2008; 8:698-704; PMID:18690830.
    • (2008) Anticancer Agents Med Chem , vol.8 , pp. 698-704
    • Zhang, Y.1    Xu, W.2
  • 8
    • 34548101379 scopus 로고    scopus 로고
    • The mitotic checkpoint in cancer therapy
    • PMID:16258280
    • Tao W. The mitotic checkpoint in cancer therapy. Cell Cycle 2005; 4:1495-9; PMID:16258280; http:// dx.doi.org/10.4161/cc.4.11.2130.
    • (2005) Cell Cycle , vol.4 , pp. 1495-1499
    • Tao, W.1
  • 9
    • 0026739078 scopus 로고
    • Mitotic spindle organization by a plus-end-directed microtubule motor
    • PMID:1406972
    • Sawin KE, LeGuellec K, Philippe M, Mitchison TJ. Mitotic spindle organization by a plus-end-directed microtubule motor. Nature 1992; 359:540-3; PMID:1406972; http://dx.doi.org/10.1038/359540a0.
    • (1992) Nature , vol.359 , pp. 540-543
    • Sawin, K.E.1    LeGuellec, K.2    Philippe, M.3    Mitchison, T.J.4
  • 10
    • 0029417238 scopus 로고
    • cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • PMID:8548803
    • cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 1995; 83:1159-69; PMID:8548803; http://dx.doi. org/10.1016/0092-8674(95) 90142-6.
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1    Lane, H.A.2    D'Hérin, P.3    Harper, M.4    Kress, M.5    Nigg, E.A.6
  • 11
    • 4444245218 scopus 로고    scopus 로고
    • Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells
    • PMID:15210851
    • Lee EA, Keutmann MK, Dowling ML, Harris E, Chan G, Kao GD. Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells. Mol Cancer Ther 2004; 3:661-9; PMID:15210851.
    • (2004) Mol Cancer Ther , vol.3 , pp. 661-669
    • Lee, E.A.1    Keutmann, M.K.2    Dowling, M.L.3    Harris, E.4    Chan, G.5    Kao, G.D.6
  • 12
    • 0042926426 scopus 로고    scopus 로고
    • Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers
    • PMID:12937152
    • Masuda A, Maeno K, Nakagawa T, Saito H, Takahashi T. Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers. Am J Pathol 2003; 163:1109-16; PMID:12937152; http://dx.doi.org/10.1016/S0002-9440(10)63470-0.
    • (2003) Am J Pathol , vol.163 , pp. 1109-1116
    • Masuda, A.1    Maeno, K.2    Nakagawa, T.3    Saito, H.4    Takahashi, T.5
  • 13
    • 1942474378 scopus 로고    scopus 로고
    • Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint
    • PMID:15059905
    • Sudo T, Nitta M, Saya H, Ueno NT. Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res 2004; 64:2502-8; PMID:15059905; http://dx.doi.org/10.1158/0008-5472.CAN-03-2013.
    • (2004) Cancer Res , vol.64 , pp. 2502-2508
    • Sudo, T.1    Nitta, M.2    Saya, H.3    Ueno, N.T.4
  • 14
    • 0028029834 scopus 로고
    • High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells
    • PMID:7526093
    • Tang C, Willingham MC, Reed JC, Miyashita T, Ray S, Ponnathpur V, et al. High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells. Leukemia 1994; 8:1960-9; PMID:7526093.
    • (1994) Leukemia , vol.8 , pp. 1960-1969
    • Tang, C.1    Willingham, M.C.2    Reed, J.C.3    Miyashita, T.4    Ray, S.5    Ponnathpur, V.6
  • 15
    • 0031045308 scopus 로고    scopus 로고
    • Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells
    • PMID:9009089
    • Huang Y, Ibrado AM, Reed JC, Bullock G, Ray S, Tang C, et al. Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells. Leukemia 1997; 11:253-7; PMID:9009089; http:// dx.doi.org/10.1038/sj.leu.2400557.
    • (1997) Leukemia , vol.11 , pp. 253-257
    • Huang, Y.1    Ibrado, A.M.2    Reed, J.C.3    Bullock, G.4    Ray, S.5    Tang, C.6
  • 16
    • 0030758777 scopus 로고    scopus 로고
    • Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization
    • PMID:9202030
    • Giannakakou P, Sackett DL, Kang YK, Zhan Z, Buters JT, Fojo T, et al. Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. J Biol Chem 1997; 272:17118-25; PMID:9202030; http://dx.doi. org/10.1074/jbc.272.27.17118.
    • (1997) J Biol Chem , vol.272 , pp. 17118-17125
    • Giannakakou, P.1    Sackett, D.L.2    Kang, Y.K.3    Zhan, Z.4    Buters, J.T.5    Fojo, T.6
  • 18
    • 33750455086 scopus 로고    scopus 로고
    • Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint
    • PMID:17041103
    • Chin GM, Herbst R. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint. Mol Cancer Ther 2006; 5:2580-91; PMID:17041103; http://dx.doi. org/10.1158/1535-7163.MCT- 06-0201.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2580-2591
    • Chin, G.M.1    Herbst, R.2
  • 19
    • 44849127993 scopus 로고    scopus 로고
    • Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5
    • PMID:18451153
    • Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008; 68:3269-76; PMID:18451153; http://dx.doi.org/10.1158/0008-5472.CAN-07-6699.
    • (2008) Cancer Res , vol.68 , pp. 3269-3276
    • Shi, J.1    Orth, J.D.2    Mitchison, T.3
  • 20
    • 34347379049 scopus 로고    scopus 로고
    • p63: Revving up epithelial stem-cell potential
    • PMID:17603506
    • Blanpain C, Fuchs E. p63: revving up epithelial stem-cell potential. Nat Cell Biol 2007; 9:731-3; PMID:17603506; http://dx.doi.org/10.1038/ ncb0707-731.
    • (2007) Nat Cell Biol , vol.9 , pp. 731-733
    • Blanpain, C.1    Fuchs, E.2
  • 21
    • 48249148324 scopus 로고    scopus 로고
    • Label-retaining cells of the bladder: Candidate urothelial stem cells
    • PMID:18367656
    • Kurzrock EA, Lieu DK, Degraffenried LA, Chan CW, Isseroff RR. Label-retaining cells of the bladder: candidate urothelial stem cells. Am J Physiol Renal Physiol 2008; 294:1415-21; PMID:18367656; http://dx.doi. org/10.1152/ajprenal.00533.2007.
    • (2008) Am J Physiol Renal Physiol , vol.294 , pp. 1415-1421
    • Kurzrock, E.A.1    Lieu, D.K.2    Degraffenried, L.A.3    Chan, C.W.4    Isseroff, R.R.5
  • 22
    • 79952747169 scopus 로고    scopus 로고
    • Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression
    • PMID:21356385
    • Karni-Schmidt O, Castillo-Martin M, Shen TH, Gladoun N, Domingo-Domenech J, Sanchez-Carbayo M, et al. Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. Am J Pathol 2011; 178:1350- 60; PMID:21356385; http://dx.doi.org/10.1016/j. ajpath.2010.11.061.
    • (2011) Am J Pathol , vol.178 , pp. 1350-1360
    • Karni-Schmidt, O.1    Castillo-Martin, M.2    Shen, T.H.3    Gladoun, N.4    Domingo-Domenech, J.5    Sanchez-Carbayo, M.6
  • 23
    • 0036791603 scopus 로고    scopus 로고
    • Loss of p63 expression is associated with tumor progression in bladder cancer
    • PMID:12368193
    • Urist MJ, Di Como CJ, Lu ML, Charytonowicz E, Verbel D, Crum CP, et al. Loss of p63 expression is associated with tumor progression in bladder cancer. Am J Pathol 2002; 161:1199-206; PMID:12368193; http://dx.doi.org/10.1016/S0002- 9440(10)64396-9.
    • (2002) Am J Pathol , vol.161 , pp. 1199-1206
    • Urist, M.J.1    Di Como, C.J.2    Lu, M.L.3    Charytonowicz, E.4    Verbel, D.5    Crum, C.P.6
  • 24
    • 84855579092 scopus 로고    scopus 로고
    • p63 expression defines a lethal subset of muscle-invasive bladder cancers
    • PMID:22253920
    • Choi W, Shah JB, Tran M, Svatek R, Marquis L, Lee IL, et al. p63 expression defines a lethal subset of muscle-invasive bladder cancers. PLoS One 2012; 7:30206; PMID:22253920; http://dx.doi.org/10.1371/journal. pone.0030206.
    • (2012) PLoS One , vol.7 , pp. 30206
    • Choi, W.1    Shah, J.B.2    Tran, M.3    Svatek, R.4    Marquis, L.5    Lee, I.L.6
  • 25
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • PMID:11357141
    • Evan GI, Vousden KH. Proliferation, cell cycle and apoptosis in cancer. Nature 2001; 411:342-8; PMID:11357141; http://dx.doi. org/10.1038/35077213.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 26
    • 0028241451 scopus 로고
    • Cytotoxicity of the anticancer agents cisplatin and taxol during cell proliferation and the cell cycle
    • PMID:7911457
    • Donaldson KL, Goolsby GL, Wahl AF. Cytotoxicity of the anticancer agents cisplatin and taxol during cell proliferation and the cell cycle. Int J Cancer 1994; 57:847-55; PMID:7911457; http://dx.doi. org/10.1002/ijc.2910570614.
    • (1994) Int J Cancer , vol.57 , pp. 847-855
    • Donaldson, K.L.1    Goolsby, G.L.2    Wahl, A.F.3
  • 27
    • 19044363045 scopus 로고    scopus 로고
    • DeltaNp63 induces beta-catenin nuclear accumulation and signaling
    • PMID:12086851
    • Patturajan M, Nomoto S, Sommer M, Fomenkov A, Hibi K, Zangen R, et al. DeltaNp63 induces beta-catenin nuclear accumulation and signaling. Cancer Cell 2002; 1:369-79; PMID:12086851; http://dx.doi. org/10.1016/S1535-6108(02)00057-0.
    • (2002) Cancer Cell , vol.1 , pp. 369-379
    • Patturajan, M.1    Nomoto, S.2    Sommer, M.3    Fomenkov, A.4    Hibi, K.5    Zangen, R.6
  • 28
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • PMID:9727977
    • He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, et al. Identification of c-MYC as a target of the APC pathway. Science 1998; 281:1509- 12; PMID:9727977; http://dx.doi.org/10.1126/science. 281.5382.1509.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3    Hermeking, H.4    Zawel, L.5    Da Costa, L.T.6
  • 29
    • 57349146621 scopus 로고    scopus 로고
    • A genomewide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression
    • PMID:18852287
    • Yochum GS, Cleland R, Goodman RH. A genomewide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol 2008; 28:7368- 79; PMID:18852287; http://dx.doi.org/ 10.1128/ MCB.00744-08.
    • (2008) Mol Cell Biol , vol.28 , pp. 7368-7379
    • Yochum, G.S.1    Cleland, R.2    Goodman, R.H.3
  • 30
    • 76249105057 scopus 로고    scopus 로고
    • A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers
    • PMID:19966299
    • Yochum GS, Sherrick CM, Macpartlin M, Goodman RH. A beta-catenin/TCF- coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Proc Natl Acad Sci USA 2010; 107:145- 50; PMID:19966299; http://dx.doi.org/10. 1073/ pnas.0912294107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 145-150
    • Yochum, G.S.1    Sherrick, C.M.2    Macpartlin, M.3    Goodman, R.H.4
  • 31
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • PMID:1555236
    • Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69:119-28; PMID:1555236; http://dx.doi.org/10.1016/0092- 8674(92)90123-T.
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1    Wyllie, A.H.2    Gilbert, C.S.3    Littlewood, T.D.4    Land, H.5    Brooks, M.6
  • 32
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • PMID:1923514
    • Askew DS, Ashmun RA, Simmons BC, Cleveland JL. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 1991; 6:1915-22; PMID:1923514.
    • (1991) Oncogene , vol.6 , pp. 1915-1922
    • Askew, D.S.1    Ashmun, R.A.2    Simmons, B.C.3    Cleveland, J.L.4
  • 33
    • 33748925553 scopus 로고    scopus 로고
    • Clinical model of lifetime cost of treating bladder cancer and associated complications
    • PMID:16979735
    • Avritscher EB, Cooksley CD, Grossman HB, Sabichi AL, Hamblin L, Dinney CP, et al. Clinical model of lifetime cost of treating bladder cancer and associated complications. Urology 2006; 68:549-53; PMID:16979735; http://dx.doi.org/10.1016/j.urology. 2006.03.062.
    • (2006) Urology , vol.68 , pp. 549-553
    • Avritscher, E.B.1    Cooksley, C.D.2    Grossman, H.B.3    Sabichi, A.L.4    Hamblin, L.5    Dinney, C.P.6
  • 34
    • 0035887279 scopus 로고    scopus 로고
    • Integrated therapy for locally advanced bladder cancer: Final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC
    • PMID:11600601
    • Millikan R, Dinney C, Swanson D, Sweeney P, Ro JY, Smith TL, et al. Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC. J Clin Oncol 2001; 19:4005-13; PMID:11600601.
    • (2001) J Clin Oncol , vol.19 , pp. 4005-4013
    • Millikan, R.1    Dinney, C.2    Swanson, D.3    Sweeney, P.4    Ro, J.Y.5    Smith, T.L.6
  • 35
    • 0041429507 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer
    • PMID:12944571
    • Grossman HB, Natale RB, Tangen CM, Speights VO, Vogelzang NJ, Trump DL, et al. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003; 349:859-66; PMID:12944571; http:// dx.doi.org/10.1056/NEJMoa022148.
    • (2003) N Engl J Med , vol.349 , pp. 859-866
    • Grossman, H.B.1    Natale, R.B.2    Tangen, C.M.3    Speights, V.O.4    Vogelzang, N.J.5    Trump, D.L.6
  • 37
    • 79151474407 scopus 로고    scopus 로고
    • A 20-gene model for molecular nodal staging of bladder cancer: Development and prospective assessment
    • PMID:21256081
    • Smith SC, Baras AS, Dancik G, Ru Y, Ding KF, Moskaluk CA, et al. A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment. Lancet Oncol 2011; 12:137-43; PMID:21256081; http://dx.doi.org/10.1016/S1470-2045(10)70296-5.
    • (2011) Lancet Oncol , vol.12 , pp. 137-143
    • Smith, S.C.1    Baras, A.S.2    Dancik, G.3    Ru, Y.4    Ding, K.F.5    Moskaluk, C.A.6
  • 38
    • 77950194890 scopus 로고    scopus 로고
    • The COXEN principle: Translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer
    • PMID:20160033
    • Smith SC, Baras AS, Lee JK, Theodorescu D. The COXEN principle: translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer. Cancer Res 2010; 70:1753-8; PMID:20160033; http://dx.doi. org/10.1158/0008-5472.CAN-09-3562.
    • (2010) Cancer Res , vol.70 , pp. 1753-1758
    • Smith, S.C.1    Baras, A.S.2    Lee, J.K.3    Theodorescu, D.4
  • 39
    • 76649134077 scopus 로고    scopus 로고
    • Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer
    • PMID:20012924
    • McConkey DJ, Choi W, Marquis L, Martin F, Williams MB, Shah J, et al. Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer. Cancer Metastasis Rev 2009; 28:335- 44; PMID:20012924; http://dx.doi.org/10.1007/s10555-009-9194-7.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 335-344
    • McConkey, D.J.1    Choi, W.2    Marquis, L.3    Martin, F.4    Williams, M.B.5    Shah, J.6
  • 40
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR- 205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • PMID:18376396
    • Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR- 205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10:593- 601; PMID:18376396; http://dx.doi.org/10.1038/ncb1722.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 41
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • PMID:19487818
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119:1420- 8; PMID:19487818; http://dx.doi.org/10.1172/ JCI39104.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 42
    • 0034234312 scopus 로고    scopus 로고
    • Frequent alteration of p63 expression in human primary bladder carcinomas
    • PMID:10910040
    • Park BJ, Lee SJ, Kim JI, Lee SJ, Lee CH, Chang SG, et al. Frequent alteration of p63 expression in human primary bladder carcinomas. Cancer Res 2000; 60:3370- 4; PMID:10910040.
    • (2000) Cancer Res , vol.60 , pp. 3370-3374
    • Park, B.J.1    Lee, S.J.2    Kim, J.I.3    Lee, S.J.4    Lee, C.H.5    Chang, S.G.6
  • 43
    • 0028051625 scopus 로고
    • Accumulation of nuclear p53 and tumor progression in bladder cancer
    • PMID:7935683
    • Esrig D, Elmajian D, Groshen S, Freeman JA, Stein JP, Chen SC, et al. Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 1994; 331:1259-64; PMID:7935683; http://dx.doi. org/10.1056/ NEJM199411103311903.
    • (1994) N Engl J Med , vol.331 , pp. 1259-1264
    • Esrig, D.1    Elmajian, D.2    Groshen, S.3    Freeman, J.A.4    Stein, J.P.5    Chen, S.C.6
  • 44
    • 0027759847 scopus 로고
    • p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade and stage in bladder cancer
    • PMID:7901994
    • Esrig D, Spruck CH, 3rd, Nichols PW, Chaiwun B, Steven K, Groshen S, et al. p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade and stage in bladder cancer. Am J Pathol 1993; 143:1389-97; PMID:7901994.
    • (1993) Am J Pathol , vol.143 , pp. 1389-1397
    • Esrig, D.1    Spruck III, C.H.2    Nichols, P.W.3    Chaiwun, B.4    Steven, K.5    Groshen, S.6
  • 45
    • 0027411102 scopus 로고
    • Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: A marker for disease progression
    • PMID:7677935
    • Sarkis AS, Dalbagni G, Cordon-Cardo C, Zhang ZF, Sheinfeld J, Fair WR, et al. Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: a marker for disease progression. J Natl Cancer Inst 1993; 85:53-9; PMID:7677935; http://dx.doi. org/10.1093/jnci/85.1.53.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 53-59
    • Sarkis, A.S.1    Dalbagni, G.2    Cordon-Cardo, C.3    Zhang, Z.F.4    Sheinfeld, J.5    Fair, W.R.6
  • 46
    • 78149483788 scopus 로고    scopus 로고
    • FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
    • PMID:21072204
    • Kompier LC, Lurkin I, van der Aa MN, van Rhijn BW, van der Kwast TH, Zwarthoff EC. FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PLoS One 2010; 5:13821; PMID:21072204; http://dx.doi.org/10.1371/journal.pone.0013821.
    • (2010) PLoS One , vol.5 , pp. 13821
    • Kompier, L.C.1    Lurkin, I.2    Van Der Aa, M.N.3    Van Rhijn, B.W.4    Van Der Kwast, T.H.5    Zwarthoff, E.C.6
  • 47
    • 1542405934 scopus 로고    scopus 로고
    • FGFR3 and p53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma
    • PMID:15026322
    • van Rhijn BW, van der Kwast TH, Vis AN, Kirkels WJ, Boevé ER, Jöbsis AC, et al. FGFR3 and p53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma. Cancer Res 2004; 64:1911- 4; PMID:15026322; http://dx.doi.org/10.1158/0008-5472.CAN-03-2421.
    • (2004) Cancer Res , vol.64 , pp. 1911-1914
    • Van Rhijn, B.W.1    Van Der Kwast, T.H.2    Vis, A.N.3    Kirkels, W.J.4    Boevé, E.R.5    Jöbsis, A.C.6
  • 48
    • 80052266351 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
    • PMID:21822268
    • Gui Y, Guo G, Huang Y, Hu X, Tang A, Gao S, et al. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet 2011; 43:875-8; PMID:21822268; http://dx.doi. org/10.1038/ng.907.
    • (2011) Nat Genet , vol.43 , pp. 875-878
    • Gui, Y.1    Guo, G.2    Huang, Y.3    Hu, X.4    Tang, A.5    Gao, S.6
  • 49
    • 0029155694 scopus 로고
    • Isolation and characterization of meta-static variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice
    • PMID:7658585
    • Dinney CP, Fishbeck R, Singh RK, Eve B, Pathak S, Brown N, et al. Isolation and characterization of meta-static variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice. J Urol 1995; 154:1532-8; PMID:7658585; http://dx.doi.org/10.1016/S0022-5347(01)66923-4.
    • (1995) J Urol , vol.154 , pp. 1532-1538
    • Dinney, C.P.1    Fishbeck, R.2    Singh, R.K.3    Eve, B.4    Pathak, S.5    Brown, N.6
  • 50
    • 78549284338 scopus 로고    scopus 로고
    • Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells
    • PMID:20814238
    • Metwalli AR, Khanbolooki S, Jinesh G, Sundi D, Shah JB, Shrader M, et al. Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells. Cancer Biol Ther 2010; 10:885- 92; PMID:20814238; http://dx.doi.org/10.4161/ cbt.10.9.13237.
    • (2010) Cancer Biol Ther , vol.10 , pp. 885-892
    • Metwalli, A.R.1    Khanbolooki, S.2    Jinesh, G.3    Sundi, D.4    Shah, J.B.5    Shrader, M.6
  • 51
    • 80054765267 scopus 로고    scopus 로고
    • Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63
    • PMID:21207227
    • Chow SE, Chang YL, Chuang SF, Wang JS. Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. Cancer Chemother Pharmacol 2011; 68:835-45; PMID:21207227; http://dx.doi.org/10.1007/ s00280-010-1552-1.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 835-845
    • Chow, S.E.1    Chang, Y.L.2    Chuang, S.F.3    Wang, J.S.4
  • 52
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small micro-array experiments
    • PMID:14668230
    • Wright GW, Simon RM. A random variance model for detection of differential gene expression in small micro-array experiments. Bioinformatics 2003; 19:2448-55; PMID:14668230; http://dx.doi.org/10.1093/bioinformatics/ btg345.
    • (2003) Bioinformatics , vol.19 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 53
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
    • PMID:19584296
    • Arumugam T, Ramachandran V, Fournier KF, Wang H, Marquis L, Abbruzzese JL, et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res 2009; 69:5820-8; PMID:19584296; http://dx.doi.org/10.1158/0008-5472.CAN-08-2819.
    • (2009) Cancer Res , vol.69 , pp. 5820-5828
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3    Wang, H.4    Marquis, L.5    Abbruzzese, J.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.