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Volumn 114, Issue 5, 2012, Pages 520-526

Simultaneous quantification of serum phytosterols and cholesterol precursors using a simple gas chromatographic method

Author keywords

Analytical parameters; Gas chromatography; Phytosterols; Serum; Sterols; Validation

Indexed keywords


EID: 84861132492     PISSN: 14387697     EISSN: 14389312     Source Type: Journal    
DOI: 10.1002/ejlt.201100331     Document Type: Article
Times cited : (20)

References (33)
  • 1
    • 77950861552 scopus 로고    scopus 로고
    • Very high plant stanol intake and serum plant stanols and non-cholesterol sterols
    • Gylling, H., Hallikainen, M., Nissinen, M. J., Simonen, P., Miettinen, T. A., Very high plant stanol intake and serum plant stanols and non-cholesterol sterols. Eur. J. Nutr. 2010, 49, 111- 117.
    • (2010) Eur. J. Nutr. , vol.49 , pp. 111-117
    • Gylling, H.1    Hallikainen, M.2    Nissinen, M.J.3    Simonen, P.4    Miettinen, T.A.5
  • 2
    • 69949136579 scopus 로고    scopus 로고
    • Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean diet
    • Escurriol, V., Cofán, M., Serra, M., Bulló, M. et al., Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean diet. Eur. J. Nutr. 2009, 48, 373- 382.
    • (2009) Eur. J. Nutr. , vol.48 , pp. 373-382
    • Escurriol, V.1    Cofán, M.2    Serra, M.3    Bulló, M.4
  • 3
    • 77957903949 scopus 로고    scopus 로고
    • Effects of phytosterol ester-enriched low-fat milk on serum lipoprotein profile in mildly hypercholesterolaemic patients are not related to dietary cholesterol or saturated fat intake
    • Hernández-Mijares, A., Bañuls, C., Rocha, M., Morillas, C. et al., Effects of phytosterol ester-enriched low-fat milk on serum lipoprotein profile in mildly hypercholesterolaemic patients are not related to dietary cholesterol or saturated fat intake. Br. J. Nutr. 2010, 104, 1018- 1025.
    • (2010) Br. J. Nutr. , vol.104 , pp. 1018-1025
    • Hernández-Mijares, A.1    Bañuls, C.2    Rocha, M.3    Morillas, C.4
  • 4
    • 79951510425 scopus 로고    scopus 로고
    • Non-cholesterol sterols in serum and endarterectomized carotid arteries after a short-term plant stanol and sterol ester challenge
    • Miettinen, T. A., Nissinen, M., Lepäntalo, M., Albäck, A. et al., Non-cholesterol sterols in serum and endarterectomized carotid arteries after a short-term plant stanol and sterol ester challenge. Nutr. Metab. Cardiovasc. Dis. 2011, 21, 182- 188.
    • (2011) Nutr. Metab. Cardiovasc. Dis. , vol.21 , pp. 182-188
    • Miettinen, T.A.1    Nissinen, M.2    Lepäntalo, M.3    Albäck, A.4
  • 5
    • 80051471067 scopus 로고    scopus 로고
    • Current and new insights on phytosterol oxides in plant sterol-enriched food
    • García-Llatas, G., Rodríguez-Estrada, M. T., Current and new insights on phytosterol oxides in plant sterol-enriched food. Chem. Phys. Lipids 2011, 164, 607- 624.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 607-624
    • García-Llatas, G.1    Rodríguez-Estrada, M.T.2
  • 6
    • 0025794067 scopus 로고
    • Use of determinations of 7-lathosterol (5α-cholest-7-en-3β-ol) and other cholesterol precursors in serum in the study and treatment of disturbances of sterol metabolism, particularly cerebrotendinous xanthomatosis
    • Wolthers, B. G., Walrecht, H. T., van der Molen, J. C., Nagel, G. T. et al., Use of determinations of 7-lathosterol (5α-cholest-7-en-3β-ol) and other cholesterol precursors in serum in the study and treatment of disturbances of sterol metabolism, particularly cerebrotendinous xanthomatosis. J. Lipid Res. 1991, 32, 603- 612.
    • (1991) J. Lipid Res. , vol.32 , pp. 603-612
    • Wolthers, B.G.1    Walrecht, H.T.2    van der Molen, J.C.3    Nagel, G.T.4
  • 7
    • 3442881581 scopus 로고    scopus 로고
    • High dietary intake of phytosterol esters decreases carotenoids and increases plasma plant sterol levels with no additional cholesterol lowering
    • Clifton, P. M., Noakes, M., Ross, D., Fassoulakis, A. et al., High dietary intake of phytosterol esters decreases carotenoids and increases plasma plant sterol levels with no additional cholesterol lowering. J. Lipid Res. 2004, 45, 1493- 1499.
    • (2004) J. Lipid Res. , vol.45 , pp. 1493-1499
    • Clifton, P.M.1    Noakes, M.2    Ross, D.3    Fassoulakis, A.4
  • 8
    • 40949164211 scopus 로고    scopus 로고
    • The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes
    • Simonen, P., Gylling, H., Miettinen, T. A., The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes. Atherosclerosis 2008, 197, 883- 888.
    • (2008) Atherosclerosis , vol.197 , pp. 883-888
    • Simonen, P.1    Gylling, H.2    Miettinen, T.A.3
  • 10
    • 33749523918 scopus 로고    scopus 로고
    • Plasma concentrations of plant sterols: Physiology and relationship with coronary heart disease
    • Chan, Y. M., Varady, K. A., Lin, Y., Trautwein, E. et al., Plasma concentrations of plant sterols: Physiology and relationship with coronary heart disease. Nutr. Rev. 2006, 64, 385- 402.
    • (2006) Nutr. Rev. , vol.64 , pp. 385-402
    • Chan, Y.M.1    Varady, K.A.2    Lin, Y.3    Trautwein, E.4
  • 11
    • 0034019728 scopus 로고    scopus 로고
    • Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients-relation to basal serum cholestanol
    • Miettinen, T., Strandberg, T., Gylling, H., Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients-relation to basal serum cholestanol. Artherioscler. Thromb. Vasc. Biol. 2000, 20, 1340- 1346.
    • (2000) Artherioscler. Thromb. Vasc. Biol. , vol.20 , pp. 1340-1346
    • Miettinen, T.1    Strandberg, T.2    Gylling, H.3
  • 12
    • 0035940733 scopus 로고    scopus 로고
    • Plasma non-cholesterol sterols
    • Kuksis, A., Plasma non-cholesterol sterols. J. Chromatogr. A 2001, 935, 203- 236.
    • (2001) J. Chromatogr. A , vol.935 , pp. 203-236
    • Kuksis, A.1
  • 13
    • 3042640736 scopus 로고    scopus 로고
    • High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs
    • Lütjohann, D., Stroick, M., Bertshc, T., Kühl, S. et al., High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs. Steroids 2004, 69, 431- 438.
    • (2004) Steroids , vol.69 , pp. 431-438
    • Lütjohann, D.1    Stroick, M.2    Bertshc, T.3    Kühl, S.4
  • 14
    • 34247240561 scopus 로고    scopus 로고
    • Gas chromatographic-mass spectrometric determination of brain levels of alpha-cholest-8-en-3 beta-ol (lathosterol)
    • Luzón-Toro, B., Zafra-Gómez, A., Ballesteros, O., Gas chromatographic-mass spectrometric determination of brain levels of alpha-cholest-8-en-3 beta-ol (lathosterol). J. Chromatogr. B 2007, 850, 177- 182.
    • (2007) J. Chromatogr. B , vol.850 , pp. 177-182
    • Luzón-Toro, B.1    Zafra-Gómez, A.2    Ballesteros, O.3
  • 15
    • 77955051100 scopus 로고    scopus 로고
    • Quantitative analysis of five sterols in amniotic fluid by GC-MS: Application to the diagnosis of cholesterol biosynthesis defects
    • Amaral, C., Gallardo, E., Rodrigues, R., Pinto Leite, R. et al., Quantitative analysis of five sterols in amniotic fluid by GC-MS: Application to the diagnosis of cholesterol biosynthesis defects. J. Chromatogr. B 2010, 878, 2130- 2136.
    • (2010) J. Chromatogr. B , vol.878 , pp. 2130-2136
    • Amaral, C.1    Gallardo, E.2    Rodrigues, R.3    Pinto Leite, R.4
  • 16
    • 0032851393 scopus 로고    scopus 로고
    • Precise quantitative determination of phytosterols, stanols, and cholesterol metabolites in human serum by capillary gas-liquid chromatography
    • Phillips, K. M., Ruggio, D. M., Bailey, J. A., Precise quantitative determination of phytosterols, stanols, and cholesterol metabolites in human serum by capillary gas-liquid chromatography. J. Chromatogr. B 1999, 732, 17- 29.
    • (1999) J. Chromatogr. B , vol.732 , pp. 17-29
    • Phillips, K.M.1    Ruggio, D.M.2    Bailey, J.A.3
  • 17
    • 33748151339 scopus 로고    scopus 로고
    • Simultaneous determination of plasmatic phytosterols and cholesterol precursors using gas chromatography-mass spectrometry (GC-MS) with selective ion monitoring (SIM)
    • Ahmida, H. S. M., Bertucci, P., Franzò, L., Massoud, R. et al., Simultaneous determination of plasmatic phytosterols and cholesterol precursors using gas chromatography-mass spectrometry (GC-MS) with selective ion monitoring (SIM). J. Chromatogr. B 2006, 842, 43- 47.
    • (2006) J. Chromatogr. B , vol.842 , pp. 43-47
    • Ahmida, H.S.M.1    Bertucci, P.2    Franzò, L.3    Massoud, R.4
  • 18
    • 0028852402 scopus 로고
    • Simultaneous measurement of phytosterols (campesterol and beta-sitosterol) and 7-ketocholesterol in human lipoproteins by capillary column gas-chromatography
    • Dyer, R. G., Hetherington, C. S., Alberti, K. G. M. M., Laker, M. F., Simultaneous measurement of phytosterols (campesterol and beta-sitosterol) and 7-ketocholesterol in human lipoproteins by capillary column gas-chromatography. J. Chromatogr. B 1995, 663, 1- 7.
    • (1995) J. Chromatogr. B , vol.663 , pp. 1-7
    • Dyer, R.G.1    Hetherington, C.S.2    Alberti, K.G.M.M.3    Laker, M.F.4
  • 19
    • 18144389061 scopus 로고    scopus 로고
    • Determination of sterols in biological samples by SPME with on-fiber derivatization and GC
    • Domeño, C., Ruiz, B., Nerín, C., Determination of sterols in biological samples by SPME with on-fiber derivatization and GC. Anal. Bioanal. Chem. 2005, 381, 1576- 1583.
    • (2005) Anal. Bioanal. Chem. , vol.381 , pp. 1576-1583
    • Domeño, C.1    Ruiz, B.2    Nerín, C.3
  • 20
    • 33745109326 scopus 로고    scopus 로고
    • High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels
    • Thelen, K. M., Laaksonen, R., Päivä, H., Lehtimäki, T., Lütjohann, D., High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels. J. Clin. Pharmacol. 2006, 46, 812- 816.
    • (2006) J. Clin. Pharmacol. , vol.46 , pp. 812-816
    • Thelen, K.M.1    Laaksonen, R.2    Päivä, H.3    Lehtimäki, T.4    Lütjohann, D.5
  • 21
    • 34247859014 scopus 로고    scopus 로고
    • Customary use of plant sterol and plant stanol enriched margarine is associated with changes in serum plant sterol and stanol concentrations in humans
    • Fransen, H. P., de Jong, N., Wolfs, M., Verhagen, H. et al., Customary use of plant sterol and plant stanol enriched margarine is associated with changes in serum plant sterol and stanol concentrations in humans. J. Nutr. 2007, 137, 1301- 1306.
    • (2007) J. Nutr. , vol.137 , pp. 1301-1306
    • Fransen, H.P.1    de Jong, N.2    Wolfs, M.3    Verhagen, H.4
  • 22
    • 79959358167 scopus 로고    scopus 로고
    • Simultaneous determination of trace sterols in complicated biological samples by gas chromatography-mass spectrometry coupled with extraction using β-sitosterol magnetic molecularly imprinted polymer beads
    • Zhang, Z., Tan, W., Hu, Y., Li, G., Simultaneous determination of trace sterols in complicated biological samples by gas chromatography-mass spectrometry coupled with extraction using β-sitosterol magnetic molecularly imprinted polymer beads. J. Chromatogr. A 2011, 1218, 4275- 4283.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 4275-4283
    • Zhang, Z.1    Tan, W.2    Hu, Y.3    Li, G.4
  • 23
    • 11244261408 scopus 로고    scopus 로고
    • Rapid quantification of free and esterified phytosterols in human serum using APPI-LC-MS/MS
    • Lembcke, J., Ceglarek, U., Fiedler, G. M., Baumann, S. et al., Rapid quantification of free and esterified phytosterols in human serum using APPI-LC-MS/MS. J. Lipid Res. 2005, 46, 21- 26.
    • (2005) J. Lipid Res. , vol.46 , pp. 21-26
    • Lembcke, J.1    Ceglarek, U.2    Fiedler, G.M.3    Baumann, S.4
  • 24
    • 77955426065 scopus 로고    scopus 로고
    • Highly sensitive and specific analysis of sterol profiles in biological samples by HPLC-ESI-MS/MS
    • Honda, A., Miyazaki, T., Ikegami, T., Iwamoto, J. et al., Highly sensitive and specific analysis of sterol profiles in biological samples by HPLC-ESI-MS/MS. J. Steroid Biochem. Mol. Biol. 2010, 121, 556- 564.
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.121 , pp. 556-564
    • Honda, A.1    Miyazaki, T.2    Ikegami, T.3    Iwamoto, J.4
  • 25
    • 77954895552 scopus 로고    scopus 로고
    • Simultaneous determination of beta-sitosterol, campesterol, stigmasterol, and brassicasterol in serum by high-performance liquid chromatography with electrochemical detection
    • Ito, N., Hakamata, H., Kusu, F., Simultaneous determination of beta-sitosterol, campesterol, stigmasterol, and brassicasterol in serum by high-performance liquid chromatography with electrochemical detection. Anal. Methods 2010, 2, 174- 179.
    • (2010) Anal. Methods , vol.2 , pp. 174-179
    • Ito, N.1    Hakamata, H.2    Kusu, F.3
  • 26
    • 79952899864 scopus 로고    scopus 로고
    • Simultaneous determination of serum lathosterol and cholesterol by semi-micro high-performance liquid chromatography with electrochemical detection
    • Hojo, K., Hakamata, H., Kusu, F., Simultaneous determination of serum lathosterol and cholesterol by semi-micro high-performance liquid chromatography with electrochemical detection. J. Chromatogr. B 2011, 879, 751- 755.
    • (2011) J. Chromatogr. B , vol.879 , pp. 751-755
    • Hojo, K.1    Hakamata, H.2    Kusu, F.3
  • 27
    • 0029068338 scopus 로고
    • Adsorption of oxysterols on different microtube materials during silanyzation prior to gas-chromatographic determination
    • Guardiola, F., Codony, R., Rafecas, M., Boatella, J., Adsorption of oxysterols on different microtube materials during silanyzation prior to gas-chromatographic determination. J. Chromatogr. A 1995, 705, 396- 399.
    • (1995) J. Chromatogr. A , vol.705 , pp. 396-399
    • Guardiola, F.1    Codony, R.2    Rafecas, M.3    Boatella, J.4
  • 28
    • 40849087737 scopus 로고    scopus 로고
    • Validation of a gas chromatography-mass spectrometry method for the analysis of sterol oxidation products in serum
    • Menéndez-Carreño, M., García-Herreros, C., Astiasarán, I., Ansorena, D., Validation of a gas chromatography-mass spectrometry method for the analysis of sterol oxidation products in serum. J. Chromatogr. B 2008, 864, 61- 68.
    • (2008) J. Chromatogr. B , vol.864 , pp. 61-68
    • Menéndez-Carreño, M.1    García-Herreros, C.2    Astiasarán, I.3    Ansorena, D.4
  • 29
    • 84871629942 scopus 로고    scopus 로고
    • International Conference on Harmonisation (ICH) of technical requirements for registration of pharmaceuticals for human use (2005, step 4 version). ICH Harmonised tripartite guideline. Available at: Accessed September 2011.
    • International Conference on Harmonisation (ICH) of technical requirements for registration of pharmaceuticals for human use (2005, step 4 version). ICH Harmonised tripartite guideline. Available at: Accessed September 2011.
  • 30
    • 0022130712 scopus 로고
    • Estimation of the limit of detection in chromatography
    • Knoll, J. E., Estimation of the limit of detection in chromatography. J. Chromatogr. Sci. 1985, 23, 422- 425.
    • (1985) J. Chromatogr. Sci. , vol.23 , pp. 422-425
    • Knoll, J.E.1
  • 31
    • 0027512873 scopus 로고
    • International coordination and validation of analytical methods
    • Horwitz, W., International coordination and validation of analytical methods. Food Addit. Contam. 1993, 10, 61- 69.
    • (1993) Food Addit. Contam. , vol.10 , pp. 61-69
    • Horwitz, W.1
  • 32
    • 33847312344 scopus 로고    scopus 로고
    • A practical guide to analytical method validation, including measurement uncertainty and accuracy profiles
    • González, A. G., Herrador, M. A., A practical guide to analytical method validation, including measurement uncertainty and accuracy profiles. Trends Anal. Chem. 2007, 26, 227- 238.
    • (2007) Trends Anal. Chem. , vol.26 , pp. 227-238
    • González, A.G.1    Herrador, M.A.2
  • 33
    • 77950607537 scopus 로고    scopus 로고
    • Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohort
    • Escurriol, V., Cofán, M., Moreno-Iribas, C., Larrañaga, N. et al., Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohort. J. Lipid Res. 2010, 51, 618- 624.
    • (2010) J. Lipid Res. , vol.51 , pp. 618-624
    • Escurriol, V.1    Cofán, M.2    Moreno-Iribas, C.3    Larrañaga, N.4


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