Development of a low toxicity, effective pdna vector based on noncovalent assembly of bioresponsive amino-β-cyclodextrin:adamantane-poly(vinyl alcohol)-poly(ethylene glycol) transfection complexes

Bioconjugate Chemistry

Volumn 23, Issue 5, 2012, Pages 933-940

  Kulkarni, Aditya ^a   Deng, Wei ^a   Hyun, Seok Hee ^a   Thompson, David H ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CONDENSATION; CYTOTOXICITY; ETHYLENE GLYCOL; GENE TRANSFER; LANTHANUM COMPOUNDS; MOLECULAR BIOLOGY; NUCLEIC ACIDS; POLYOLS; POLYVINYL ALCOHOLS; SELF ASSEMBLY;

ADAMANTANES; CATIONIC POLYMERS; CATIONICS; HOST:GUEST; LOW TOXICITY; NONCOVALENT ASSEMBLIES; POLY (VINYL ALCOHOL) (PVA); POLY(VINYL ALCOHOL); POLY(VINYL ALCOHOL) (PVA); Β-CD;

POLYETHYLENE GLYCOLS;

ACETAL; ADAMANTANE; AMINO BETA CYCLODEXTRIN ADAMANTANE MACROGOL 2000 POLYVINYL ALCOHOL CONJUGATE; BENZYLIDINE; BETA CYCLODEXTRIN DERIVATIVE; DRUG VEHICLE; MACROGOL; MACROGOL 2000; NUCLEIC ACID; PLASMID DNA; POLYVINYL ALCOHOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONJUGATION; CYTOTOXICITY; DNA VECTOR; DRUG DESIGN; DRUG SYNTHESIS; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL;

ADAMANTANE; AMINATION; BETA-CYCLODEXTRINS; CELL SURVIVAL; DNA; HELA CELLS; HUMANS; PLASMIDS; POLYETHYLENE GLYCOLS; POLYVINYL ALCOHOL; TRANSFECTION;

EID: 84861130065     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc2005158     Document Type: Article

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