Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis

Molecular BioSystems

Volumn 8, Issue 6, 2012, Pages 1806-1814

  Liebal, Ulf W ^a   Sappa, Praveen K ^b   Millat, Thomas ^a   Steil, Leif ^b   Homuth, Georg ^b   Völker, Uwe ^b   Wolkenhauer, Olaf ^a,c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS SUBTILIS;

BACTERIAL PROTEIN; BETA GALACTOSIDASE; CARRIER PROTEIN; MESSENGER RNA; PEPTIDE HYDROLASE; RSBW PROTEIN, BACTERIA; SIGB PROTEIN, BACTERIA; SIGMA FACTOR;

ADAPTATION; ARTICLE; BACILLUS SUBTILIS; BIOLOGICAL MODEL; ENZYME STABILITY; GENETIC TRANSCRIPTION; GENETICS; LACTOSE OPERON; METABOLISM; METHODOLOGY; MUTATION; PHYSIOLOGY; PROTEIN DEGRADATION; SOLUTION AND SOLUBILITY; SYSTEMS BIOLOGY;

ADAPTATION, BIOLOGICAL; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BETA-GALACTOSIDASE; CARRIER PROTEINS; ENZYME STABILITY; LAC OPERON; MODELS, BIOLOGICAL; MUTATION; PEPTIDE HYDROLASES; PROTEOLYSIS; RNA, MESSENGER; SIGMA FACTOR; SOLUTIONS; SYSTEMS BIOLOGY; TRANSCRIPTION, GENETIC;

EID: 84861128131     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c2mb25031d     Document Type: Article

References (47)

1. C. W. Price, General stress response, Bacillus Subtilis and Its Closest Relatives: From Genes to Cells, American Society for Microbiology, 2002, pp. 369-384
2. M. Hecker J. Pane-Farre U. Völker SigB-Dependent General Stress Response in Bacillus subtilis and Related Gram-Positive Bacteria Annu. Rev. Microbiol. 2007 61 215 236
3. M. A. van der Horst J. Key K. J. Hellingwerf Photosensing in chemotrophic, non-phototrophic bacteria: let there be light sensing too Trends Microbiol. 2007 15 12 554 562
4. C. W. Price P. Fawcett H. Ceremonie N. Su C. K. Murphy P. Youngman Genome-wide analysis of the general stress response in Bacillus subtilis Mol. Microbiol. 2001 41 4 757 774
5. J. D. Helmann M. F. W. Wu P. A. Kobel F. J. Gamo M. Wilson M. M. Morshedi M. Navre C. Paddon Global transcriptional response of Bacillus subtilis to heat shock J. Bacteriol. 2001 183 24 7318 7328
6. A. Petersohn M. Brigulla S. Haas J. D. Hoheisel U. Völker M. Hecker Global Analysis of the General Stress Response of Bacillus subtilis J. Bacteriol. 2001 183 19 5617 5631
7. M. Hecker U. Völker General stress response of Bacillus subtilis and other bacteria Adv. Microb. Physiol. 2001 44 35 91
8. W. G. Haldenwang The sigma factors of Bacillus subtilis Microbiol. Rev. 1995 59 1 1 30
9. X. Yang C. M. Kang M. S. Brody C. W. Price Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor Genes Dev. 1996 10 18 2265 2275
10. A. Benson W. Haldenwang Bacillus subtilis SigmaB is regulated by a binding protein (RsbW) that blocks its association with core RNA polymerase Proc. Natl. Acad. Sci. U. S. A. 1993 90 6 2330 2334
11. A. Dufour W. G. Haldenwang Interactions between a Bacillus subtilis anti-sigma factor (RsbW) and its antagonist (RsbV) J. Bacteriol. 1994 176 7 1813 1820
12. A. K. Benson W. G. Haldenwang Regulation of SigmaB levels and activity in Bacillus subtilis J. Bacteriol. 1993 175 8 2347 2356
13. U. Völker A. Völker W. G. Haldenwang Reactivation of the Bacillus subtilis anti-sigma B antagonist, RsbV, by stress-or starvation-induced phosphatase activities J. Bacteriol. 1996 178 18 5456 5463
14. U. Völker A. Völker B. Maul M. Hecker A. Dufour W. G. Haldenwang Separate mechanisms activate SigmaB of Bacillus subtilis in response to environmental and metabolic stresses J. Bacteriol. 1995 177 13 3771 3780
15. K. Vijay M. S. Brody E. Fredlund C. W. Price A PP2C phosphatase containing a PAS domain is required to convey signals of energy stress to the SigmaB transcription factor of Bacillus subtilis Mol. Microbiol. 2000 35 1 180 188
16. J. Pane-Farre R. J. Lewis J. Stülke The RsbRST Stress Module in Bacteria: A Signalling System That May Interact with Different Output Modules J. Mol. Microbiol. Biotechnol. 2005 9 2 65 76
17. A. Francez-Charlot J. Frunzke C. Reichen J. Z. Ebneter B. Gourion J. A. Vorholt Sigma factor mimicry involved in regulation of general stress response Proc. Natl. Acad. Sci. U. S. A. 2009 106 9 3467 3472
18. U. W. Liebal T. Millat I. G. de Jong O. P. Kuipers U. Völker O. Wolkenhauer How mathematical modelling elucidates signalling in Bacillus subtilis Mol. Microbiol. 2010 77 5 1083 1095
19. O. A. Igoshin M. S. Brody C. W. Price M. A. Savageau Distinctive Topologies of Partner-switching Signaling Networks Correlate with their Physiological Roles J. Mol. Biol. 2007 369 5 1333 1352
20. M. Brigulla T. Hoffmann A. Krisp A. Völker E. Bremer U. Völker Chill Induction of the SigB-Dependent General Stress Response in Bacillus subtilis and Its Contribution to Low-Temperature Adaptation J. Bacteriol. 2003 185 15 4305 4314
21. T. J. Silhavy J. R. Beckwith Uses of lac fusions for the study of biological problems Microbiol. Mol. Biol. Rev. 1985 49 4 398 418
22. I. G. Serebriiskii E. A. Golemis Uses of lacZ to study gene function: evaluation of β-galactosidase assays employed in the yeast two-hybrid system Anal. Biochem. 2000 285 1 1 15
23. M. Santillán M. C. Mackey Quantitative approaches to the study of bistability in the lac operon of Escherichia coli J. R. Soc. Interface 2008 5 Suppl 1 S29
24. D. Cazorla J. X. Feliu A. Villaverde Variable specific activity of Escherichia coli β-galactosidase in bacterial cells Biotechnol. Bioeng. 2001 72 3 255 260
25. A. Mogk R. Hayward W. Schumann Integrative vectors for constructing single-copy transcriptional fusions between Bacillus subtilis promoters and various reporter genes encoding heat-stable enzymes Gene 1996 182 1-2 33 36
26. U. Zuber W. Schumann CIRCE, a novel heat shock element involved in regulation of heat shock operon dnaK of Bacillus subtilis J. Bacteriol. 1994 176 5 1359 1363
27. S. Nakano E. Küster-Schöck A. D. Grossman P. Zuber Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis Proc. Natl. Acad. Sci. U. S. A. 2003 100 23 13603 13608
28. K. J. Newberry S. Nakano P. Zuber R. G. Brennan Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the α C-terminal domain of RNA polymerase Proc. Natl. Acad. Sci. U. S. A. 2005 102 44 15839 15844
29. A. Reder D. Höper C. Weinberg U. Gerth M. Fraunholz M. Hecker The Spx paralogue MgsR (YqgZ) controls a subregulon within the general stress response of Bacillus subtilis Mol. Microbiol. 2008 69 5 1104 1120
30. A. Y. Mitrophanov E. A. Groisman Signal integration in bacterial two-component regulatory systems Genes Dev. 2008 22 19 2601 2611
31. E. Krüger U. Völker M. Hecker Stress induction of clpC in Bacillus subtilis and its involvement in stress tolerance J. Bacteriol. 1994 176 11 3360 3367
32. O. Schrögel R. Allmansberger Optimisation of the BgaB reporter system: determination of transcriptional regulation of stress responsive genes in Bacillus subtilis FEMS Microbiol. Lett. 1997 153 1 237 243
33. B J. Bacteriol. 2000 182 5 1452 1456
34. T.-J. Kim T. A. Gaidenko C. W. Price A Multicomponent Protein Complex Mediates Environmental Stress Signaling in Bacillus subtilis J. Mol. Biol. 2004 341 1 135 150
35. O. Delumeau S. Dutta M. Brigulla G. Kuhnke S. W. Hardwick U. Völker M. D. Yudkin R. J. Lewis Functional and Structural Characterization of RsbU, a Stress Signaling Protein Phosphatase 2C J. Biol. Chem. 2004 279 39 40927 40937
36. B Inducibility J. Bacteriol. 2005 187 24 8520 8525
37. T. Msadek When the going gets tough: survival strategies and environmental signaling networks in Bacillus subtilis Trends Microbiol. 1999 7 5 201 207
38. U. Völker A. Dufour W. G. Haldenwang The Bacillus subtilis rsbU gene product is necessary for RsbX-dependent regulation of sigma B J. Bacteriol. 1995 177 1 114 122
39. J. C. Locke J. W. Young M. Fontes M. J. Jiménez M. B. Elowitz Stochastic Pulse Regulation in Bacterial Stress Response Science (New York, NY) 2011 334 6054 366 369
40. B J. Bacteriol. 2007 189 17 6168 6175
41. W. Ma A. Trusina H. El-Samad W. A. Lim C. Tang Defining Network Topologies that Can Achieve Biochemical Adaptation Cell 2009 138 4 760 773
42. E. Botella M. Fogg M. Jules S. Piersma G. Doherty A. Hansen E. Denham et al. pBaSysBioII: an integrative plasmid generating gfp transcriptional fusions for high-throughput analysis of gene expression in Bacillus subtilis Microbiology 2010 156 6 1600 1608
43. T. Msadek V. Dartois F. Kunst M. L. Herbaud F. Denizot G. Rapoport ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation Mol. Microbiol. 1998 27 5 899 914
44. G. Homuth S. Masuda A. Mogk Y. Kobayashi W. Schumann The dnaK operon of Bacillus subtilis is heptacistronic J. Bacteriol. 1997 179 4 1153 1164
45. C. Eymann G. Homuth C. Scharf M. Hecker Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis J. Bacteriol. 2002 184 9 2500 2520
46. H. Schmidt M. Jirstrand Systems Biology Toolbox for MATLAB: a computational platform for research in systems biology Bioinformatics 2006 22 4 514 515
47. A. I. F. Vaz L. N. Vicente A particle swarm pattern search method for bound constrained global optimization J. Global Optim. 2007 39 2 197 219