Influence of some formulation variables on the optimization of pH-dependent, colon-targeted, sustained-release mesalamine microspheres

AAPS PharmSciTech

Volumn 13, Issue 1, 2012, Pages 75-84

  El Bary, Ahmed Abd ^a   Aboelwafa, Ahmed A ^a   Al Sharabi, Ibrahim M ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Colon; Ethylcellulose; Eudragit; Mesalamine; Sustained release

Indexed keywords

ETHYL CELLULOSE; EUDRAGIT; MESALAZINE; MICROSPHERE;

ARTICLE; COLON; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; EMULSION; EVAPORATION; IN VITRO STUDY; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PULSATILE DRUG RELEASE; SCANNING ELECTRON MICROSCOPY; SUSTAINED RELEASE FORMULATION;

CHEMISTRY, PHARMACEUTICAL; COLON; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; MESALAMINE; MICROSPHERES; POLYMETHACRYLIC ACIDS;

EID: 84861101568     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-011-9721-z     Document Type: Article

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