-
2
-
-
0035857020
-
New drug targets for type 2 diabetes and the metabolic syndrome
-
DOI 10.1038/414821a
-
Moller D E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 2001 414 821-827 (Pubitemid 34000786)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 821-827
-
-
Moller, D.E.1
-
3
-
-
0037317489
-
PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity
-
Zhang Z Y., Lee S Y. PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity. Exp Opin Invest Drugs 2003 12 223-233
-
(2003)
Exp Opin Invest Drugs
, vol.12
, pp. 223-233
-
-
Zhang, Z.Y.1
Lee, S.Y.2
-
4
-
-
0031036223
-
Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin
-
DOI 10.1074/jbc.272.3.1639
-
Bandyopadhyay D, Kusari A, Kenner K A., Liu F, Chernoff J, Gustafson T A., Kusari J. PTP1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin. J Biol Chem 1997 272 1639-1645 (Pubitemid 27043246)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.3
, pp. 1639-1645
-
-
Bandyopadhyay, D.1
Kusari, A.2
Kenner, K.A.3
Liu, F.4
Chernoff, J.5
Gustafson, T.A.6
Kusari, J.7
-
5
-
-
36549059075
-
Inhibition of the protein tyrosine phosphatase PTP1B: Potential therapy for obesity, insulin resistance and type-2 diabetes mellitus
-
DOI 10.1016/j.beem.2007.08.004, PII S1521690X07000814, New Therapies for Diabetes
-
Koren S, Fantus I G. Inhibition of the protein tyrosine phosphatase 1B: potential therapy for obesity, insulin resistance and type II diabetes mellitus. Best Pract Res Clin Endocrinol Metab 2007 21 621-640 (Pubitemid 350185860)
-
(2007)
Best Practice and Research in Clinical Endocrinology and Metabolism
, vol.21
, Issue.4
, pp. 621-640
-
-
Koren, S.1
Fantus, I.G.2
-
6
-
-
0033525870
-
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase 1B gene
-
Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy A L., Normandin D, Cheng A, Himms-Hagen J, Chan C C., Ramachandran C, Gresser M J., Tremblay M L., Kennedy B. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase 1B gene. Science 1999 283 1544-1548
-
(1999)
Science
, vol.283
, pp. 1544-1548
-
-
Elchebly, M.1
Payette, P.2
Michaliszyn, E.3
Cromlish, W.4
Collins, S.5
Loy, A.L.6
Normandin, D.7
Cheng, A.8
Himms-Hagen, J.9
Chan, C.C.10
Ramachandran, C.11
Gresser, M.J.12
Tremblay, M.L.13
Kennedy, B.14
-
7
-
-
80052175121
-
Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and proinflammatory mediators in vitro
-
Baumgartner L, Sosa S, Atanasov A G., Bodensieck A, Fakhrudin N, Bauer J, Del Favero G, Ponti C, Heiss E H., Schwaiger S, Ladurner A, Widowitz U, Della Loggia R, Rollinger J M., Werz O, Bauer R, Dirsch V M., Tubaro A, Stuppner H. Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and proinflammatory mediators in vitro. J Nat Prod 2011 74 1779-1786
-
(2011)
J Nat Prod
, vol.74
, pp. 1779-1786
-
-
Baumgartner, L.1
Sosa, S.2
Atanasov, A.G.3
Bodensieck, A.4
Fakhrudin, N.5
Bauer, J.6
Del Favero, G.7
Ponti, C.8
Heiss, E.H.9
Schwaiger, S.10
Ladurner, A.11
Widowitz, U.12
Della Loggia, R.13
Rollinger, J.M.14
Werz, O.15
Bauer, R.16
Dirsch, V.M.17
Tubaro, A.18
Stuppner, H.19
-
8
-
-
84861097050
-
Synthesis, molecular docking and PTP1B inhibitory activity of functionalized 4,5-dihydronaphtofurans and dibenzofurans
-
Dixit M, Saeed U, Kumar A, Siddigi M, Tamrakar A K., Srivastava A K., Goel A. Synthesis, molecular docking and PTP1B inhibitory activity of functionalized 4,5-dihydronaphtofurans and dibenzofurans. Med Chem 2010 20 3329-3337
-
(2010)
Med Chem
, vol.20
, pp. 3329-3337
-
-
Dixit, M.1
Saeed, U.2
Kumar, A.3
Siddigi, M.4
Tamrakar, A.K.5
Srivastava, A.K.6
Goel, A.7
-
9
-
-
33748882713
-
Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake
-
DOI 10.1016/j.bbagen.2006.05.009, PII S0304416506001607
-
Zhang W, Hong D, Zhou Y, Zhang Y, Shen Q, Li J Y., Hu L H., Li J. Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and glucose uptake. Biochim Biophys Acta 2006 1760 1505-1512 (Pubitemid 44428024)
-
(2006)
Biochimica et Biophysica Acta - General Subjects
, vol.1760
, Issue.10
, pp. 1505-1512
-
-
Zhang, W.1
Hong, D.2
Zhou, Y.3
Zhang, Y.4
Shen, Q.5
Li, J.-y.6
Hu, L.-h.7
Li, J.8
-
10
-
-
77957223996
-
Bioactivity-guided isolation of 1,2,3,4,6-penta- O -galloyl-D- glucopyranose from Paeonia lactiflora as PTP1B inhibitor
-
Baumgartner R R., Steinmann D, Heiss E H., Atanasov A G., Ganzera M, Stuppner H, Dirsch V M. Bioactivity-guided isolation of 1,2,3,4,6-penta- O -galloyl-D-glucopyranose from Paeonia lactiflora as PTP1B inhibitor. J Nat Prod 2010 73 1578-1581
-
(2010)
J Nat Prod
, vol.73
, pp. 1578-1581
-
-
Baumgartner, R.R.1
Steinmann, D.2
Heiss, E.H.3
Atanasov, A.G.4
Ganzera, M.5
Stuppner, H.6
Dirsch, V.M.7
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