Layered inorganic nanocomposites: A promising carrier for 5-fluorouracil (5-FU)

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 1, 2012, Pages 91-101

  Kevadiya, Bhavesh D ^a,d   Patel, Tapan A ^b   Jhala, Devendrasinh D ^b   Thumbar, Rahul P ^c   Brahmbhatt, Harshad ^a   Pandya, Maharshi P ^d   Rajkumar, Shalini ^d   Jena, Prasant K ^d   Joshi, Ghanshyam V ^a   Gadhia, Pankaj K ^c   Tripathi, C B ^e   Bajaj, Hari C ^a  

^a CSIR CENTRAL SALT AND MARINE CHEMICALS RESEARCH INSTITUTE   (India)

^b GUJARAT UNIVERSITY   (India)

^c VEER NARMAD SOUTH GUJARAT UNIVERSITY   (India)

^d NIRMA UNIVERSITY   (India)

^e GOVERNMENT MEDICAL COLLEGE   (India)

Author keywords

Controlled drug release; Genotoxicity; Intercalation; Na + clay; Nanocomposites

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHITOSAN; FLUOROURACIL; NANOCOMPOSITE; SODIUM ION;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANCER CELL; CANCER CHEMOTHERAPY; CELL VIABILITY; CLAY; COMET ASSAY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DNA DAMAGE; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG RELEASE; DRUG TISSUE LEVEL; GENOTOXICITY; HEART; IC 50; IN VITRO STUDY; IN VIVO STUDY; INTERCALATION COMPLEX; KIDNEY; LIVER HISTOLOGY; LIVER TOXICITY; LUNG; LYMPHOCYTE CULTURE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SPLEEN; TESTIS; THERMAL ANALYSIS; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BENTONITE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CHITOSAN; COMET ASSAY; DELAYED-ACTION PREPARATIONS; DNA DAMAGE; DRUG CARRIERS; FLUOROURACIL; HUMANS; LIVER; LYMPHOCYTES; MALE; NANOCOMPOSITES; RATS; RATS, WISTAR; STATIC ELECTRICITY; TISSUE DISTRIBUTION; X-RAY DIFFRACTION;

EID: 84861093781     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.01.004     Document Type: Article

References (32)

1. S.N. Gupta, and N. Aggarwal A gastro-retentive floating delivery system for 5-fluorouracil Asian J. Pharm. Sci. 2 2007 143 149
2. M.S. Lesniak, and H. Brem Targeted therapy for brain tumours Nat. Rev. Drug Discov. 3 2004 499 508
3. B. Arica, S. Calis, H.S. Kas, M.F. Sargon, and A.A. Hincal 5-Fluorouracil encapsulated alginate beads for the treatment of breast cancer Int. J. Pharm. 242 2002 267 269
4. F. Qian, N. Nasongkla, and J. Gao Membrane-encased polymer millirods for sustained release of 5-fluorouracil J. Biomed. Mater. Res. 61 2002 203 211
5. V.S. Shenoy, R.P. Gude, and R.S. Ramachandra Murthy In vitro anticancer evaluation of 5-fluorouracil lipid nanoparticles using B16F10 melanoma cell Lines Int. Nano Lett. 2 2012 14 24
6. D. Elias, T. de Baere, L. Sideris, and M. Ducreux Regional chemotherapeutic techniques for liver tumors: current knowledge and future directions Surg. Clin. North Am. 84 2004 607 625
7. Y. Wang, C. Gong, L. Yang, Q. Wu, S. Shi, H. Shi, Z. Qian, and Y. Wei 5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice BMC Cancer 10 2010 402
8. P. Kalantarian, A.R. Najafabadi, I. Haririan, A. Vatanara, Y. Yamini, M. Darabi, and K. Gilani Preparation of 5-fluorouracil nanoparticles by supercritical antisolvents for pulmonary delivery Int. J. Nanomed. 5 2010 763 770
9. I. Jungkyun, B. Goutam, K. Wanil, K. Kyong-Tai, and Sung-Kee Chung A blood-brain barrier permeable derivative of 5-fluorouracil: preparation, intracellular localization, and mouse tissue distribution Bull. Korean Chem. Soc. 32 2011 873 879
10. D.B. Longley, D.P. Harkin, and P.G. Johnston 5-Fluorouracil: mechanisms of action and clinical strategies Nat. Rev. Cancer 3 2003 330 338
11. P. Noordhuis, U. Holwerda, C.L. Van der Wilt, C.J. Van Groeningen, K. Smid, S. Meijer, H.M. Pinedo, and G.J. Peters 5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers Ann. Oncol. 15 2004 1025 1032
12. N.H. Nicolay, D.P. Berry, and R.A. Sharma Liver metastases from colorectal cancer: radioembolization with systemic therapy Nat. Rev. Clin. Oncol. 6 2009 687 697
13. R.B. Diasio, and Z. Lu Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy J. Clin. Oncol. 12 11 1994 2239 2242
14. E.C. Gamelin, E.M. Danquechin-Dorval, Y.F. Dumesnil, P.J. Maillart, M.J. Goudier, and P.C. Burtin Relationship between 5-fluorouracil (5-FU) dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU Cancer 77 3 1996 441 451
15. E. Aranda, E. Diaz-Rubio, A. Cervantes, A. Anton-Torres, A. Carrato, and T. Massuti Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with weekly high-dose 48-hour continuous-infusion fluorouracil for advanced colorectal cancer: a Spanish Cooperative Group for Gastrointestinal Tumor Therapy (TTD) study Ann. Oncol. 9 7 1998 727 731
16. R.L. Schilsky, J. Hohneker, M.J. Ratain, L. Janisch, L. Smetzer, and V.S. Lucas 3rd Phase I clinical and pharmacologic study of eniluracil plus fluorouracil in patients with advanced cancer J. Clin. Oncol. 16 4 1998 1450 1457
17. S. Li, A. Wang, W. Jiang, and Z. Guan Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles BMC Cancer 8 103 2008 1 9
18. B.D. Kevadiya, G.V. Joshi, and H.C. Bajaj Layered bionanocomposites as carrier for procainamide Int. J. Pharm. 388 2010 280 286
19. Y. Dong, and S.S. Feng Poly (d,l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs Biomaterials 26 2005 6068 6076
20. S.S. Feng, L. Mei, P. Anitha, C.W. Gan, and W. Zhou Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of docetaxel Biomaterials 30 2009 3206 3297
21. F.H. Lin, Y.H. Lee, C.H. Jian, J.M. Wong, M.J. Shieh, and C.Y. Wang A study of purified montmorillonite intercalated with 5-fluorouracil as drug carrier Biomaterials 23 2002 1981 1987
22. R.W. Korsmeyer, R. Gurny, E. Doelker, P. Buri, and N.A. Peppas Mechanisms of solute release from porous hydrophilic polymers Int. J. Pharm. 15 1983 25 35
23. D.A. Hungerford Leukocytes cultured from small inoculum of whole blood and the preparation of chromosomes by treatment with hypotonic KCI Stain. Technol. 40 1965 333 338
24. N.P. Singh, M.T. McCoy, R.R. Tice, and E.L. Schneider A simple technique for quantitation of low levels of damage in individual cells Exp. Cell Res. 175 1988 184 191
25. 2 and γ-irradiation, with the alkaline comet assay Mut. Res. 383 1997 71 80
26. Z. Rahman, K. Kohli, S.Q. Zhang, R.K. Khar, M. Ali, and N.A. Charoo In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil J. Pharm. Pharm. 60 2008 615 623
27. M. Darder, M. Colilla, and E. Ruiz-Hitzky Biopolymer-clay nanocomposites based on chitosan intercalated in montmorillonite Chem. Mater. 15 2003 3774 3780
28. Y. Shchipunov, N. Ivanova, and V. Silantev Bionanocomposites formed by in situ charged chitosan with clay Green Chem. 11 2009 1758 1761
29. M. Kondo, and M. Araie Iontophoresis of 5-fluorourocil into the conjunctiva and sclera Invest. Ophthal. Vis. Sci. 30 3 1989 583 585
30. B.N. Singh, R.B. Singh, and J. Singh Effects of ionization and penetration enhancers on the transdermal delivery of 5-fluorouracil through excised human stratum corneum Int. J. Pharm. 298 2005 98 107
31. G.V. Joshi, B.D. Kevadiya, H.A. Patel, H.C. Bajaj, and R.V. Jasra Montmorillonite as a drug delivery system: intercalation and in vitro release of timolol maleate Int. J. Pharm. 374 2009 53 57
32. Q. Yuan, J. Shah, S. Hein, and R.D.K. Misra Controlled and extended drug release behavior of chitosan-based nanoparticle carrier Acta Biomater. 6 2010 1140 1148