A novel Phex mutation in a new mouse model of hypophosphatemic rickets

Journal of Cellular Biochemistry

Volumn 113, Issue 7, 2012, Pages 2432-2441

  Owen, Celeste ^a   Chen, Frieda ^b   Flenniken, Ann M ^a   Osborne, Lucy R ^a,b   Ichikawa, Shoji ^c   Adamson, S Lee ^a,b,d   Rossant, Janet ^a,b,e   Aubin, Jane E ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

bone; endopeptidase; mineralization; N Ethyl N nitrosourea mutagenesis

Indexed keywords

ADENINE; ALKALINE PHOSPHATASE; CALCIUM; ETHYLNITROSOUREA; GENOMIC DNA; MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN; MESSENGER RNA; OSTEOCALCIN; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; PHOSPHORUS; SCLEROSTIN; SIALOPROTEIN; THYMINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MARROW CELL; CELL DIFFERENTIATION; CLINICAL FEATURE; CONTROLLED STUDY; EXON; FEMALE; FEMUR; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GROWTH RETARDATION; HEMIZYGOTE; IMMUNOBLOTTING; MALE; MINERALIZATION; MOUSE; MOUSE MUTANT; MUTAGENESIS; NONHUMAN; OSTEOBLAST; OSTEOMALACIA; POINT MUTATION; PRIORITY JOURNAL; STOP CODON; STROMA CELL; WILD TYPE; X LINKED HYPOPHOSPHATEMIC RICKETS;

ANIMALS; BASE SEQUENCE; BONE AND BONES; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELLS, CULTURED; CHROMOSOME MAPPING; DISEASE MODELS, ANIMAL; ETHYLNITROSOUREA; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GLYCOPROTEINS; HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT; INTEGRIN-BINDING SIALOPROTEIN; MALE; MICE; MICE, INBRED C57BL; MUTAGENS; OSTEOBLASTS; OSTEOCALCIN; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; PHOSPHOPROTEINS; POINT MUTATION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; STROMAL CELLS;

MUS;

EID: 84861027682     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24115     Document Type: Article

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