Methoxetamine associated reversible cerebellar toxicity: Three cases with analytical confirmation

Clinical Toxicology

Volumn 50, Issue 5, 2012, Pages 438-440

  Shields, Jennifer E ^a   Dargan, Paul I ^b   Wood, David M ^b   Puchnarewicz, Malgorzata ^c   Davies, Susannah ^c   Waring, W Stephen ^a  

^a YORK TEACHING HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Acute toxicity; Ketamine; Methoxetamine; Nervous system; Recreational drug

Indexed keywords

4' METHYLMETHCATHINONE; CREATINE KINASE; KETAMINE; METHOXETAMINE; PSYCHOTROPIC AGENT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ADOLESCENT; ADULT; ANALYTICAL RESEARCH; ARTICLE; BLOOD PRESSURE; BODY TEMPERATURE; BRAIN TOXICITY; CASE REPORT; CEREBELLAR ATAXIA; CONSCIOUSNESS LEVEL; CREATINE KINASE BLOOD LEVEL; DROWSINESS; DRUNK SENSATION; DYSARTHRIA; ELECTROCARDIOGRAM; ENZYME ACTIVITY; GAIT; HEART RATE; HUMAN; LEUKOCYTE COUNT; MALE; MYDRIASIS; NEUTROPHIL COUNT; NYSTAGMUS; PHYSICAL EXAMINATION; PR INTERVAL; QRS COMPLEX; QT INTERVAL; SINUS TACHYCARDIA; SLURRED SPEECH; UNCONSCIOUSNESS;

ADOLESCENT; CEREBELLAR ATAXIA; CONSCIOUSNESS DISORDERS; CYCLOHEXANONES; CYCLOHEXYLAMINES; HUMANS; MALE; NEUROTOXICITY SYNDROMES; POSTURAL BALANCE; SPEECH DISORDERS; STREET DRUGS; YOUNG ADULT;

EID: 84861023782     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2012.683437     Document Type: Article

References (10)

1. Hofer KE, Grager B, Muller DM, Rauber-Luthy C, Kupferschmidt H, Rentsch KM, et al. Ketamine-like effects after recreational use of methoxetamine. Ann Emerg Med [Epub] 2012 Jan 9.
2. Gibbons S. Legal highs: Novel and emerging psychoactive drugs: A chemical overview for the toxicologist. Clin Toxicol 2012; 50:15-24.
3. Wood DM, Davies S, Puchnarewicz M, Johnston A, Dargan PI. Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. Eur J Clin Phamacol [Epub] 2011 Dec 29.
4. Mak SK, Chan MT, Bower WF, Yip SK, Hou SS, Wu BB, Man CY. Lower urinary tract changes in young adults using ketamine. J Urol 2011; 186:610-614.
5. Rosenbaum CD, Carreiro SP, Babu KM. Here today, gone tomorrowand back again. A review of herbal marijuana alternatives (K2, spice), synthetic cathinones (bath salts), kratom, salvia divinorum, methoxetamine, and piperazines. J Med Toxicol 2012; 8:15-32.
6. Ward J, Rhyee S, Plansky J, Boyer E. Methoxetamine: A novel ketamine analog and growing health-care concern. Clin Toxicol 2011; 49:874-875.
7. Waring WS, McGettigan P. Clinical toxicology and drug regulation: A United Kingdom perspective. Clin Toxicol 2011; 49:452-456.
8. Mark M. Emerging drugs of abuse: what was new yesterday is new today. J Med Toxicol. 2012;8:1-2.
9. Erowid: Methoxetamine website http://www.erowid.org/chemicals/ methoxetamine/methoxetamine.shtml [accessed 01/03/2012].
10. Kalsi SS, Wood DM, Dargan PI. The epidemiology and patterns of acute and chronic toxicity associated with recreational ketamine use. Emerg Health Threat J 2011; 4:7107.