Osteopontin expression in chronic plaque psoriasis: An association with the severity of disease

Analytical and Quantitative Cytology and Histology

Volumn 34, Issue 2, 2012, Pages 79-85

  Abdou, Asmaa Gaber ^a   El Farargy, Shawky ^a   Seleit, Iman ^a   Antar, Azaa Gaber ^a   Elhefny, Mohammed ^a   Elnaidany, Nada Farag ^b  

^a MENOUFIA UNIVERSITY   (Egypt)

^b October University for Modern Sciences and Arts   (Egypt)

Author keywords

Inflammation; Osteopontin; Psoriasis

Indexed keywords

OSTEOPONTIN;

ADULT; ARTICLE; CELL NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIUM CELL; EPIDERMIS; FEMALE; HAIR FOLLICLE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; KERATINOCYTE; MALE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PSORIASIS VULGARIS; PUVA; SEBACEOUS GLAND; SKIN BIOPSY; SWEAT GLAND;

ADOLESCENT; ADULT; AGED; BIOPSY; CHILD; CHRONIC DISEASE; DERMATITIS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; OSTEOPONTIN; PSORIASIS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84861006664     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Buback F, Renkl AC, Schulz G, Weiss JM: Osteopontin and the skin: Multiple emerging roles in cutaneous biology and pathology. Exp Dermatol 2009;18:750-759
2. Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS: Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001;107:1055-1061
3. Chiocchetti A, Indelicato M, Bensi T, Mesturini R, Giordano M, Sametti S, Castelli L, Bottarel F, Mazzarino MC, Garbarini L, Giacopelli F, Valesini G, Santoro C, Dianzani I, Ramenghi U, Dianzani U: High levels of osteopontin associated with polymorphisms in its gene are a risk factor for development of autoimmunity/lymphoproliferation. Blood 2004;103: 1376-1382
4. Tanaka K, Morimoto J, Kon S, Kimura C, Inobe M, Diao H, Hirschfeld G, Weiss JM, Uede T: Effect of osteopontin alleles on beta-glucan-induced granuloma formation in the mouse liver. Am J Pathol 2004;164:567-575
5. O'Regan A, Berman JS: Osteopontin: A key cytokine in cell mediated and granulomatous inflammation. Int J Exp Pathol 2000;81:373-390
6. Buommino E, Tufano MA, Balato N, Canozo N, Donnarumma M, Gallo L, Balato A, Ayala F: Osteopontin: A new emerging role in psoriasis. Arch Dermatol Res 2009;301:397-404
7. Louden BA, Pearce DJ, Lang W, Feldman SR: A Simplified Psoriasis Area Severity Index (SPASI) for rating psoriasis severity in clinic patients. Dermatol Online J 2004;10:7
8. Chang PL, Harkins L, Hsieh YH, Hicks P, Sappayatosok K, Yodsanga S, Swasdison S, Chambers AF, Elmets CA, Ho KJ: Osteopontin expression in normal skin and non-melanoma skin tumors. J Histochem Cytochem 2008;56:57-66
9. Chang PL, Ridall AL, Prince CW: Calcitriol regulation of osteopontin expression in mouse epidermal cells. Endocrinology 1994;135:863-869
10. Kadota J, Mizunoe S, Mito K, Mukae H, Yoshioka S, Kawakami K, Koguchi Y, Fukushima K, Kon S, Kohno S, Saito A, Uede T, Nasu M: High plasma concentrations of osteopontin in patients with interstitial pneumonia. Respir Med 2005;99: 111-117
11. Potter MR, Rittling SR, Denhardt DT, Roper RJ, Weis JH, Teuscher C, Weis JJ: Role of osteopontin in murine Lyme arthritis and host defense against Borrelia burgdorferi. Infect Immun 2002;70:1372-1381
12. Hsieh YH, Juliana MM, Hicks PH, Feng G, Elmets C, Liaw L, Chang PL: Papilloma development is delayed in osteopontinnull mice: Implicating an antiapoptosis role for osteopontin. Cancer Res 2006;66:7119-7127
13. Yu DW, Yang T, Sonoda T, Gong Y, Cao Q, Gaffney K, Jensen PJ, Freedberg IM, Lavker RM, Sun TT: Osteopontin gene is expressed in the dermal papilla of pelage follicles in a haircycle-dependent manner. J Invest Dermatol 2001;117:1554-1558
14. Feng B, Rollo EE, Denhardt DT: Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: Evidence from cell lines downregulated for OPN expression by a targeted ribozyme. Clin Exp Metastasis 1995;13:453-462
15. Schilli MB, Paus R, Menrad A: Reduction of intrafollicular apoptosis in chemotherapy-induced alopecia by topical calcitriol-analogs. J Invest Dermatol 1998;111:598-604
16. Szegedi A, Aleksza M, Gonda A, Irinyi B, Sipka S, Hunyadi J, Antal-Szalmás P: Elevated rate of Thelper1 (T(H)1) lymphocytes and serum IFN-λ levels in psoriatic patients. Immunol Lett 2003;86:277-288
17. Weiss JM, Renkl AC, Maier CS, Kimmig M, Liaw L, Ahrens T, Kon S, Maeda M, Hotta H, Uede T, Simon JC: Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med 2001:194:1219-1229
18. Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L: Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol 2007;8:74-83
19. Senger DR, Ledbetter SR, Claffey KP, Papadopoulos-Sergiou A, Peruzzi CA, Detmar M: Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 1996;149:293-305
20. Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31
21. Chen YJ, Shen JL, Wu CY, Chang YT, Chen CM, Lee FY: Elevated plasma osteopontin level is associated with occurrence of psoriasis and is an unfavorable cardiovascular risk factor in patients with psoriasis. J Am Acad Dermatol 2009;60:225-230
22. Wong CK, Lit LC, Tam LS, Li EK, Lam CW: Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxf) 2005;44:602-606
23. Okada H, Moriwaki K, Konishi K, Kobayashi T, Sugahara S, Nakamoto H, Saruta T, Suzuki H: Tubular osteopontin expression in human glomerulonephritis and renal vasculitis. Am J Kidney Dis 2000;36:498-506
24. Kitamura M, Iwabuchi K, Kitaichi N, Kon S, Kitamei H, Namba K, Yoshida K, Denhardt DT, Rittling SR, Ohno S, Uede T, Onoé K: Osteopontin aggravates experimental autoimmune uveoretinitis in mice. J Immunol 2007;178:6567-6572