Osteopontin expression in normal skin and non-melanoma skin tumors

Journal of Histochemistry and Cytochemistry

Volumn 56, Issue 1, 2008, Pages 57-66

  Chang, Pi Ling ^a   Harkins, Louie ^b   Hsieh, Yu Hua ^a   Hicks, Patricia ^a   Sappayatosok, Kraisorn ^c   Yodsanga, Somchai ^d   Swasdison, Somporn ^d   Chambers, Ann F ^e   Elmets, Craig A ^a   Ho, Kang Jey ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c SRINAKHARINWIROT UNIVERSITY   (Thailand)

^d CHULALONGKORN UNIVERSITY   (Thailand)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Actinic keratosis; Apoptosis; Basal cell carcinoma; Calcitriol; Differentiation; Epidermis; Osteopontin; Squamous cell carcinoma; Ultraviolet light

Indexed keywords

OSTEOPONTIN;

ARTICLE; BASAL CELL; BASAL CELL CARCINOMA; CELL DIFFERENTIATION; CONTROLLED STUDY; GRANULAR CELL; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEBACEOUS GLAND; SKIN; SKIN CANCER; SQUAMOUS CELL CARCINOMA; SUN EXPOSURE; SWEAT GLAND;

CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; HUMANS; IMMUNOHISTOCHEMISTRY; KERATOSIS; OSTEOPONTIN; PHOTOSENSITIVITY DISORDERS; PRECANCEROUS CONDITIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN; SKIN NEOPLASMS; SUNLIGHT;

EID: 37249014473     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.7A7325.2007     Document Type: Article

References (75)

1. Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, et al. (2002) Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst 94:513-521
2. Allan AL, George R, Vantyghem SA, Lee MW, Hodgson NC, Engel CJ, Holliday RL, et al. (2006) Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer. Am J Pathol 169:233-246
3. Atkins GJ, Anderson PH, Findlay DM, Welldon KJ, Vincent C, Zannettino AC, O'Loughlin PD, et al. (2007) Metabolism of vitamin D(3) in human osteoblasts: Evidence for autocrine and paracrine activities of 1α,25-dihydroxyvitamin D(3). Bone 40:1517-1528
4. Atkins KB, Simpson RU, Somerman MJ (1997) Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. Arch Biochem Biophys 343:157-163
5. Baccarani-Contri M, Taparelli F, Pasquali-Ronchetti I (1995) Osteopontin is a constitutive component of normal elastic fibers in human skin and aorta. Matrix Biol 14:553-560
6. Bautista DS, Xuan JW, Hota C, Chambers AF, Harris JF (1994) Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. J Biol Chem 269:23280-23285
7. Bellahcene A, Castronovo V (1995) Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer. Am J Pathol 146:95-100
8. Boudreau N, Bissell MJ (1998) Extracellular matrix signaling: integration of form and function in normal and malignant cells. Curr Opin Cell Biol 10:640-646
9. Brash DE, Ziegler A, Jonason AS, Simon JA, Kunala S, Leffell DJ (1996) Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion. J Investig Dermatol Symp Proc 1:136-142
10. Brown LF, Berse B, Van de Water L, Papadopoulos-Sergiou A, Perruzzi CA, Manseau EJ, Dvorak HF, et al. (1992) Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Mol Biol Cell 3:1169-1180
11. Brown LF, Papadopoulos-Sergiou A, Berse B, Manseau EJ, Tognazzi K, Perruzzi CA, Dvorak HF, et al. (1994) Osteopontin expression and distribution in human carcinomas. Am J Pathol 145:610-623
12. Chambers AF, Wilson SM, Kerkvliet N, O'Malley FP, Harris JF, Casson AG (1996) Osteopontin expression in lung cancer. Lung Cancer 15:311-323
13. Chang PL, Cao M, Hicks P (2003) Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells. Carcinogenesis 24:1749-1758
14. Chang PL, Prince CW (1991) 1 α,25-dihydroxyvitamin D3 stimulates synthesis and secretion of nonphosphorylated osteopontin (secreted phosphoprotein 1) in mouse JB6 epidermal cells. Cancer Res 51:2144-2150
15. Chang PL, Ridall AL, Prince CW (1994) Calcitnol regulation of osteopontin expression in mouse epidermal cells. Endocrinology 135:863-869
16. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
17. Coppola D, Szabo M, Boulware D, Muraca P, Alsarraj M, Chambers AF, Yeatman TJ (2004) Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. Clin Cancer Res 10:184-190
18. Denhardt DT, Mistretta D, Chambers AF, Krishna S, Porter JF, Raghuram S, Rittling SR (2003) Transcriptional regulation of osteopontin and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter. Clin Exp Metastasis 20:77-84
19. Devoll RE, Li W, Woods KV, Pinero GJ, Butler WT, Farach-Carson MC, Happonen RP (1999) Osteopontin (OPN) distribution in premalignant and malignant lesions of oral epithelium and expression in cell lines derived from squamous cell carcinoma of the oral cavity. J Oral Pathol Med 28:97-101
20. El-Abaseri TB, Fuhrman J, Trempus C, Shendrik I, Tennant RW, Hansen LA (2005) Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor. Cancer Res 65:3958-3965
21. Fedarko NS, Jain A, Karadag A, Van Eman MR, Fisher LW (2001) Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res 7:4060-4066
22. Fet V, Dickinson ME, Hogan BL (1989) Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance). Genomics 5:375-377
23. Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS (2001) Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin. Biochem Biophys Res Commun 280:460-465
24. Forootan SS, Foster CS, Aachi VR, Adamson J, Smith PH, Lin K, Ke Y (2006) Prognostic significance of osteopontin expression in human prostate cancer. Int J Cancer 118:2255-2261
25. Gailani MR, Stahle-Backdahl M, Leffell DJ, Glynn M, Zaphiropoulos PG, Pressman C, Unden AB, et al. (1996) The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat Genet 14:78-81
26. Graessmann M, Berg B, Fuchs B, Klein A, Graessmann A (2006) Chemotherapy resistance of mouse WAP-SVT/t breast cancer cells is mediated by osteopontin, inhibiting apoptosis downstream of caspase-3. Oncogene 26:2840-2850
27. Hamada Y, Yuki K, Okazaki M, Fujitani W, Matsumoto T, Hashida MK, Harutsugu K, et al. (2004) Osteopontin-derived peptide SWYGLR induces angiogenesis in vivo. Dent Mater J 23:650-655
28. Hirota S, Ito A, Nagoshi J, Takeda M, Kurata A, Takatsuka Y, Kohri K, et al. (1995) Expression of bone matrix protein messenger ribonucleic acids in human breast cancers. Possible involvement of osteopontin in development of calcifying foci. Lab Invest 72:64-69
29. Hotte SJ, Winquist EW, Stitt L, Wilson SM, Chambers AF (2002) Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma. Cancer 95:506-512
30. Hsieh YH, Juliana MM, Hicks PH, Feng G, Elmets C, Liaw L, Chang PL (2006) Papilloma development is delayed in osteopontin-null mice: implicating an antiapoptosis role for osteopontin. Cancer Res 66:7119-7127
31. Ibaraki K, Termine JD, Whitson SW, Young MF (1992) Bone matrix mRNA expression in differentiating fetal bovine osteoblasts. J Bone Miner Res 7:743-754
32. Kadkol SS, Lin AY, Barak V, Kalickman I, Leach L, Valyi-Nagy K, Majumdar D, et al. (2006) Osteopontin expression and serum levels in metastatic uveal melanoma: a pilot study. Invest Ophthalmol Vis Sci 47:802-806
33. Kim JH, Skates SJ, Uede T, Wong Kk KK, Schorge JO, Feltmate CM, Berkowitz RS, et al. (2002) Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA 287:1671-1679
34. Koopmann J, Fedarko NS, Jain A, Maitra A, Iacobuzio-Donahue C, Rahman A, Hruban RH, et al. (2004) Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev 13:487-491
35. Kusafuka K, Yamaguchi A, Kayano T, Takemura T (1999) Expression of bone matrix proteins, osteonectin and osteopontin, in salivary pleomorphic adenomas. Pathol Res Pract 195:733-739
36. Lecanda F, Avioli LV, Cheng SL (1997) Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem 67:386-396
37. Liaw L, Birk DE, Ballas CB, Whitsitt JS, Davidson JM, Hogan BL (1998) Altered wound healing in mice lacking a functional osteopontin gene (spp1). J Clin Invest 101:1468-1478
38. Liu JG, Zhang HZ, Wei YP, Wu C, Cao YK, Wang M (2007) Expression of Ras-GTPase-activating protein SH 3 domain binding protein and osteopontin in esophageal squamous carcinoma and their effects on prognosis. Zhonghua Wei Chang Wai Ke Za Zhi 10:73-76
39. Marks R (1995) An overview of skin cancers. Incidence and causation. Cancer 75:607-612
40. Marks R, Rennie G, Selwood TS (1988) Malignant transformation of solar keratoses to squamous cell carcinoma. Lancet 1:795-797
41. Morimoto I, Sasaki Y, Ishida S, Imai K, Tokino T (2002) Identification of the osteopontin gene as a direct target of TP53. Genes Chromosomes Cancer 33:270-278
42. Nakamachi T, Nomiyama T, Gizard F, Heywood EB, Jones KL, Zhao Y, Fuentes L, et al. (2007) PPAR{α} agonists suppress osteopontin expression in macrophages and decrease plasma levels in patients with type 2 diabetes. Diabetes 56:1662-1670
43. Nystrom T, Duner P, Hultgardh-Nilsson A (2007) A constitutive endogenous osteopontin production is important for macrophage function and differentiation. Exp Cell Res 313:1149-1160
44. Ogbureke KU, Fisher LW (2004) Expression of SIBLINGS and their partner MMPs in salivary glands. J Dent Res 83:664-670
45. Ogbureke KU, Fisher LW (2005) Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs). Kidney Int 68:155-166
46. Ogbureke KU, Fisher LW (2007) SIBLING expression patterns in duct epithelia reflect the degree of metabolic activity. J Histochem Cytochem 55:403-409
47. Pan HW, Ou YH, Peng SY, Liu SH, Lai PL, Lee PH, Sheu JC, et al. (2003) Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma. Cancer 98:119-127
48. Patarca R, Freeman GJ, Singh RP, Wei F-Y, Durfee T, Blattner F, Regnier DC, et al. (1989) Structual and functional studies of the early T lymphocyte activation (Eta-1) gene. J Exp Med 170:145-161
49. Pierceall WE, Goldberg LH, Tainsky MA, Mukhopadhyay T, Ananthaswamy HN (1991) Ras gene mutation and amplification in human nonmelanoma skin cancers. Mol Carcinog 4:196-202
50. Prince CW, Oosawa T, Butler WT, Tomana M, Bhown AS, Bhown M, Schrohenloher RE (1987) Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone. J Biol Chem 262:2900-2907
51. Qu H, Brown LF, Senger DR, Geng LL, Dvorak HF, Dvorak AM (1994) Ultrastructural immunogold localization of osteopontin in human gallbladder epithelial cells. J Histochem Cytochem 42:351-361
52. Rangaswami H, Bulbule A, Kundu GC (2006) Osteopontin: role in cell signaling and cancer progression. Trends Cell Biol 16:79-87
53. Rittling SR, Chambers AF (2004) Role of osteopontin in tumour progression. Br J Cancer 90:1877-1881
54. Rittling SR, Matsumoto HN, McKee MD, Nanci A, An XR, Novick KE, Kowalski AJ, et al. (1998) Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 13:1101-1111
55. Rittling SR, Novick KE (1997) Osteopontin expression in mammary gland development and tumorigenesis. Cell Growth Differ 8:1061-1069
56. Rivet J, Lebbe C, Urena P, Cordoliani F, Martinez F, Baglin AC, Aubert P, et al. (2006) Cutaneous calcification in patients with end-stage renal disease: a regulated process associated with in situ osteopontin expression. Arch Dermatol 142:900-906
57. Saitoh Y, Kuratsu J, Takeshima H, Yamamoto S, Ushio Y (1995) Expression of osteopontin in human glioma. Its correlation with the malignancy. Lab Invest 72:55-63
58. Sanders RJ, Mainiero F, Giancotti FG (1998) The role of integrins in tumorigenesis and metastasis. Cancer Invest 16:329-344
59. Senger DR, Perruzzi CA, Papadopoulos A (1989) Elevated expression of secreted phosphoprotein I (osteopontin, 2ar) as a consequence of neoplastic transformation. Anticancer Res 9:1291-1299
60. Shijubo N, Uede T, Kon S, Maeda M, Segawa T, Imada A, Hirasawa M, et al. (1999) Vascular endothelial growth factor and osteopontin in stage I lung adenocarcinoma. Am J Respir Crit Care Med 160:1269-1273
61. Singhal H, Bautista DS, Tonkin KS, Omalley FP, Tuck AB, Chambers AF, Harris JF (1997) Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 3:605-611
62. Somerman MJ, Berry JE, Khalkhali-Ellis Z, Osdoby P, Simpson RU (1995) Enhanced expression of alpha v integrin subunit and osteopontin during differentiation of HL-60 cells along the monocytic pathway. Exp Cell Res 216:335-341
63. Sorensen S, Justesen SJ, Johnsen AH (2003) Purification and characterization of osteopontin from human milk. Protein Expr Purif 30:238-245
64. Spencer JM, Kahn SM, Jiang W, DeLeo VA, Weinstein IB (1995) Activated ras genes occur in human actinic keratoses, premalignant precursors to squamous cell carcinomas. Arch Dermatol 131:796-800
65. Tataria M, Quarto N, Longaker MT, Sylvester KG (2006) Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells. J Pediatr Surg 41:624-632
66. Thalmann GN, Sikes RA, Devoll RE, Kiefer JA, Markwalder R, Klima I, Farach-Carson CM, et al. (1999) Osteopontin: possible role in prostate cancer progression. Clin Cancer Res 5:2271-2277
67. Tiniakos DG, Yu H, Liapis H (1998) Osteopontin expression in ovarian carcinomas and tumors of low malignant potential (LMP). Hum Pathol 29:1250-1254
68. Tunio GM, Hirota S, Nomura S, Kitamura Y (1998) Possible relation of osteopontin to development of psammoma bodies in human papillary thyroid cancer. Arch Pathol Lab Med 122:1087-1090
69. Ue T, Yokozaki H, Kitadai Y, Yamamoto S, Yasui W, Ishikawa T, Tahara E (1998) Co-expression of osteopontin and CD44v9 in gastric cancer. Int J Cancer 79:127-132
70. Verhulst A, Persy VP, Van Rompay AR, Verstrepen WA, Helbert MF, De Broe ME (2002) Osteopontin synthesis and localization along the human nephron. J Am Soc Nephrol 13:1210-1218
71. Wai PY, Kuo PC (2004) The role of Osteopontin in tumor metastasis. J Surg Res 121:228-241
72. Weiss MJ, Henthorn PS, Lafferty MA, Slaughter C, Raducha M, Harris H (1986) Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase. Proc Natl Acad Sci USA 83:7182-7186
73. Wu Y, Denhardt DT, Rittling ST (2000) Osteopontin is required for full expression of the transformed phenotype by the ras oncogene. Br J Cancer 83:156-163
74. Young MF, Kerr JM, Termine JD, Wewer UM, Wang MG, McBride OW, Fisher LW (1990) cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN). Genomics 7:491-502
75. Yu DW, Yang T, Sonoda T, Gong Y, Cao Q, Gaffney K, Jensen PJ, et al. (2001) Osteopontin gene is expressed in the dermal papilla of pelage follicles in a hair-cycle-dependent manner. J Invest Dermatol 117:1554-1558