A gallotannin-rich fraction from Caesalpinia spinosa (Molina) Kuntze displays cytotoxic activity and raises sensitivity to doxorubicin in a leukemia cell line

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Castañeda, Diana M ^a   Pombo, Luis M ^b   Urueña, Claudia P ^a   Hernandez, John F ^a   Fiorentino, Susana ^a  

^a PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^b Juan N Corpas University   (Colombia)

Author keywords

Adjuvants; C.spinosa; Gallotannins; Leukemia; Tumor

Indexed keywords

CAESALPINIA SPINOSA EXTRACT; CAMPTOTHECIN; CASPASE 3; DOXORUBICIN; ETOPOSIDE; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOL DERIVATIVE; ISOFLAVONE DERIVATIVE; PACLITAXEL; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SAPONIN DERIVATIVE; TANNIN; TRITERPENOID; UNCLASSIFIED DRUG; VINCRISTINE; ANTINEOPLASTIC AGENT; PHARMACEUTICAL VEHICLES AND ADDITIVES;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CAESALPINIA; CAESALPINIA SPINOSA; CANCER COMBINATION CHEMOTHERAPY; CELL MEMBRANE DEPOLARIZATION; CHEMICAL COMPOSITION; CHEMOSENSITIVITY; CHROMATIN CONDENSATION; CLONOGENESIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMATOPOIETIC CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MASS SPECTROMETRY; MEDICINAL PLANT; MITOCHONDRION; PHYTOCHEMISTRY; THIN LAYER CHROMATOGRAPHY; CELL LINE; CHEMISTRY; CHROMATIN; DRUG EFFECT; DRUG POTENTIATION; HEMATOPOIESIS; LEUKEMIA; METABOLISM; PHYTOTHERAPY; TUMOR CELL LINE;

ADJUVANTS, PHARMACEUTIC; ANTINEOPLASTIC AGENTS; CAESALPINIA; CASPASE 3; CELL LINE; CELL LINE, TUMOR; CHROMATIN; DOXORUBICIN; DRUG SYNERGISM; HEMATOPOIESIS; HUMANS; HYDROLYZABLE TANNINS; INHIBITORY CONCENTRATION 50; LEUKEMIA; MITOCHONDRIA; PHYTOTHERAPY; PLANT EXTRACTS;

EID: 84860997062     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-38     Document Type: Article

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