메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

Overstimulation of NMDA receptors impairs early brain development in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN; EXCITATORY AMINO ACID TRANSPORTER 1; MICROTUBULE ASSOCIATED PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; EXCITATORY AMINO ACID TRANSPORTER 2; NR1 NMDA RECEPTOR; PRIMER DNA; SLC1A2 PROTEIN, MOUSE; SLC1A3 PROTEIN, MOUSE;

EID: 84860990369     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036853     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fantemi SH, Folsom TD, (2009) The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull 35: 528-548.
    • (2009) Schizophr Bull , vol.35 , pp. 528-548
    • Fantemi, S.H.1    Folsom, T.D.2
  • 2
    • 73949136265 scopus 로고    scopus 로고
    • Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
    • Belforte JE, Zsiros V, Sklar ER, Jiang Z, Yu G, et al. (2010) Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat Neurosci 13: 76-83.
    • (2010) Nat Neurosci , vol.13 , pp. 76-83
    • Belforte, J.E.1    Zsiros, V.2    Sklar, E.R.3    Jiang, Z.4    Yu, G.5
  • 3
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR, (1991) Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148: 1301-1308.
    • (1991) Am J Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 4
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
    • Krystal JH, Karper LP, Seibyl JP, FreemanGK, DelaneyR, et al. (1994) Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51: 199-214.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3    Freeman, G.K.4    Delaney, R.5
  • 5
    • 0030749913 scopus 로고    scopus 로고
    • Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics
    • Malhotra AK, Pinals DA, Adler CM, Elman I, Clifton A, et al. (1997) Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology 17: 141-150.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 141-150
    • Malhotra, A.K.1    Pinals, D.A.2    Adler, C.M.3    Elman, I.4    Clifton, A.5
  • 6
    • 0034843738 scopus 로고    scopus 로고
    • The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
    • Goff DC, Coyle JT, (2001) The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am J Psychiatry 158: 1367-1377.
    • (2001) Am J Psychiatry , vol.158 , pp. 1367-1377
    • Goff, D.C.1    Coyle, J.T.2
  • 7
    • 33749063363 scopus 로고    scopus 로고
    • Modeling madness in mice: One piece at a time
    • Arguello PA, Gogos JA, (2006) Modeling madness in mice: One piece at a time. Neuron 52: 179-196.
    • (2006) Neuron , vol.52 , pp. 179-196
    • Arguello, P.A.1    Gogos, J.A.2
  • 9
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, et al. (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial. Nat Med 13: 1102-1107.
    • (2007) Nat Med , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3    Lowe, S.L.4    Jackson, K.A.5
  • 10
    • 80052563319 scopus 로고    scopus 로고
    • Neocortical excitation/inhibition balance in information processing and social dysfunction
    • Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, et al. (2011) Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 477: 171-178.
    • (2011) Nature , vol.477 , pp. 171-178
    • Yizhar, O.1    Fenno, L.E.2    Prigge, M.3    Schneider, F.4    Davidson, T.J.5
  • 11
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison PJ, (1999) The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122: 593-624.
    • (1999) Brain , vol.122 , pp. 593-624
    • Harrison, P.J.1
  • 12
    • 0033914076 scopus 로고    scopus 로고
    • Cellular and molecular neuropathology of the parahippocampal region in schizophrenia
    • Arnold SE, (2000) Cellular and molecular neuropathology of the parahippocampal region in schizophrenia. Ann N Y Acad Sci 911: 275-292.
    • (2000) Ann N Y Acad Sci , vol.911 , pp. 275-292
    • Arnold, S.E.1
  • 14
    • 0035101941 scopus 로고    scopus 로고
    • Perinatal brain injury: from pathogenesis to neuroprotection
    • Volpe JJ, (2001) Perinatal brain injury: from pathogenesis to neuroprotection. Ment Retard Dev Disabil Res Rev 7: 56-64.
    • (2001) Ment Retard Dev Disabil Res Rev , vol.7 , pp. 56-64
    • Volpe, J.J.1
  • 15
    • 33747042753 scopus 로고    scopus 로고
    • Indispensability of the glutamate transporters GLAST and GLT1 to brain development
    • Matsugami TR, Tanemura K, Mieda M, Nakatomi R, Yamada K, et al. (2006) Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Proc Natl Acad Sci U S A 103: 12161-12166.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12161-12166
    • Matsugami, T.R.1    Tanemura, K.2    Mieda, M.3    Nakatomi, R.4    Yamada, K.5
  • 16
    • 0027092373 scopus 로고
    • Developmental changes in distribution of NMDA receptor channel subunit mRNAs
    • Watanabe M, Inoue Y, Sakimura K, Mishina M, (1992) Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport 3: 1138-1140.
    • (1992) Neuroreport , vol.3 , pp. 1138-1140
    • Watanabe, M.1    Inoue, Y.2    Sakimura, K.3    Mishina, M.4
  • 17
    • 0025804443 scopus 로고
    • Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing
    • Monyer H, Seeburg PH, Wisden W, (1991) Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing. Neuron 6: 799-810.
    • (1991) Neuron , vol.6 , pp. 799-810
    • Monyer, H.1    Seeburg, P.H.2    Wisden, W.3
  • 18
    • 0028018273 scopus 로고
    • Kainate receptor gene expression in the developing rat brain
    • Bahn S, Volk B, Wisden W, (1994) Kainate receptor gene expression in the developing rat brain. J Neurosci 14: 5525-5547.
    • (1994) J Neurosci , vol.14 , pp. 5525-5547
    • Bahn, S.1    Volk, B.2    Wisden, W.3
  • 19
    • 0026716350 scopus 로고
    • Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat
    • Shigemoto R, Nakanishi S, Mizuno N, (1992) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. J Comp Neurol 322: 121-135.
    • (1992) J Comp Neurol , vol.322 , pp. 121-135
    • Shigemoto, R.1    Nakanishi, S.2    Mizuno, N.3
  • 20
    • 0028173680 scopus 로고
    • Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
    • Li Y, Erzurumlu RS, Chen C, Jhaveri S, Tonegawa S, (1994) Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76: 427-437.
    • (1994) Cell , vol.76 , pp. 427-437
    • Li, Y.1    Erzurumlu, R.S.2    Chen, C.3    Jhaveri, S.4    Tonegawa, S.5
  • 21
    • 0034066615 scopus 로고    scopus 로고
    • Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus
    • Aamodt SM, Shi J, Colonnese MT, Veras W, Constantine-Paton M, (2000) Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus. J Neurophysiol 83: 1580-1591.
    • (2000) J Neurophysiol , vol.83 , pp. 1580-1591
    • Aamodt, S.M.1    Shi, J.2    Colonnese, M.T.3    Veras, W.4    Constantine-Paton, M.5
  • 22
    • 0036719162 scopus 로고    scopus 로고
    • Excitatory actions of gaba during development: the nature of the nurture
    • Ben-Ari Y, (2002) Excitatory actions of gaba during development: the nature of the nurture. Nat Rev Neurosci 3: 718-739.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 718-739
    • Ben-Ari, Y.1
  • 23
    • 34147174017 scopus 로고    scopus 로고
    • Prenatal and perinatal risk factors for autism: a review and integration of findings
    • Kolevzon A, Gross R, Reichenberg A, (2007) Prenatal and perinatal risk factors for autism: a review and integration of findings. Arch Pediatr Adolesc Med 161: 326-333.
    • (2007) Arch Pediatr Adolesc Med , vol.161 , pp. 326-333
    • Kolevzon, A.1    Gross, R.2    Reichenberg, A.3
  • 24
    • 33646522416 scopus 로고    scopus 로고
    • Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia
    • Schmidt-Kastner R, van Os J, Steinbusch HMW, Schmitz C, (2006) Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia. Schizophr Res 84: 253-271.
    • (2006) Schizophr Res , vol.84 , pp. 253-271
    • Schmidt-Kastner, R.1    van Os, J.2    Steinbusch, H.M.W.3    Schmitz, C.4
  • 25
    • 32244439440 scopus 로고    scopus 로고
    • Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone
    • Weidenhofer J, Bowden NA, Scott RJ, Tooney PA, (2006) Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone. Mol Cell Neurosci 31: 243-250.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 243-250
    • Weidenhofer, J.1    Bowden, N.A.2    Scott, R.J.3    Tooney, P.A.4
  • 26
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, et al. (2008) Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320: 539-543.
    • (2008) Science , vol.320 , pp. 539-543
    • Walsh, T.1    McClellan, J.M.2    McCarthy, S.E.3    Addington, A.M.4    Pierce, S.B.5
  • 27
    • 53249142500 scopus 로고    scopus 로고
    • Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist
    • Karlsson RM, Tanaka K, Heilig M, Holmes A, (2008) Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. Biol Psychiatry 64: 810-814.
    • (2008) Biol Psychiatry , vol.64 , pp. 810-814
    • Karlsson, R.M.1    Tanaka, K.2    Heilig, M.3    Holmes, A.4
  • 28
    • 64949144447 scopus 로고    scopus 로고
    • Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia
    • Karlsson RM, Tanaka K, Saksida LM, Bussey TJ, Heilig M, et al. (2009) Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology 34: 1578-1589.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1578-1589
    • Karlsson, R.M.1    Tanaka, K.2    Saksida, L.M.3    Bussey, T.J.4    Heilig, M.5
  • 29
    • 58149089452 scopus 로고    scopus 로고
    • Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism
    • Xu S, Han JC, Morales A, Menzie CM, Williams K, et al. (2008) Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism. Cytogenet Genome Res 122: 181-187.
    • (2008) Cytogenet Genome Res , vol.122 , pp. 181-187
    • Xu, S.1    Han, J.C.2    Morales, A.3    Menzie, C.M.4    Williams, K.5
  • 30
    • 33847327313 scopus 로고    scopus 로고
    • Mapping autism risk loci using genetic linkage and chromosomal rearrangements
    • Autism Genome Project Consortium
    • Autism Genome Project Consortium, Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, et al. (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet 39: 319-328.
    • (2007) Nat Genet , vol.39 , pp. 319-328
    • Szatmari, P.1    Paterson, A.D.2    Zwaigenbaum, L.3    Roberts, W.4
  • 31
    • 35548991088 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons
    • Homayoun H, Moghaddam B, (2007) NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J Neurosci 27: 11496-11500.
    • (2007) J Neurosci , vol.27 , pp. 11496-11500
    • Homayoun, H.1    Moghaddam, B.2
  • 32
    • 2942537881 scopus 로고    scopus 로고
    • NMDA receptor hypo- function produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex
    • Jackson ME, Homayoun H, Moghaddam B, (2004) NMDA receptor hypo- function produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc Natl Acad SciUSA101: 8467-8472.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8467-8472
    • Jackson, M.E.1    Homayoun, H.2    Moghaddam, B.3
  • 33
    • 35548983971 scopus 로고    scopus 로고
    • Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine
    • Kargieman L, Santana N, Mengod G, Celada P, Artigas F, (2007) Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine. Proc Natl Acad SciUSA 104: 14843-14848.
    • (2007) Proc Natl Acad SciUSA , vol.104 , pp. 14843-14848
    • Kargieman, L.1    Santana, N.2    Mengod, G.3    Celada, P.4    Artigas, F.5
  • 34
    • 17544391947 scopus 로고    scopus 로고
    • Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice
    • Watase K, Hashimoto K, Kano M, Yamada K, Watanabe M, et al. (1998) Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci 10: 976-988.
    • (1998) Eur J Neurosci , vol.10 , pp. 976-988
    • Watase, K.1    Hashimoto, K.2    Kano, M.3    Yamada, K.4    Watanabe, M.5
  • 35
    • 0030812843 scopus 로고    scopus 로고
    • Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
    • Tanaka K, Watase K, Manabe T, Yamada K, Watanabe M, et al. (1997) Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science 276: 1699-1702.
    • (1997) Science , vol.276 , pp. 1699-1702
    • Tanaka, K.1    Watase, K.2    Manabe, T.3    Yamada, K.4    Watanabe, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.