Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15826-15835

  Senavirathne, Gayan ^a   Jaszczur, Malgorzata ^b   Auerbach, Paul A ^b   Upton, Thomas G ^b   Chelicos, Linda ^b,c   Goodman, Myron F ^b   Rueda, David ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; IN-VITRO; IN-VIVO; MECHANISTIC STUDIES; MOTIF SEQUENCE; RESONANCE ENERGY TRANSFER; SCANNING TRAJECTORY; SINGLE MOLECULE; SINGLE-MOLECULE RESOLUTION; SINGLE-STRANDED (SS) DNA; SINGLE-STRANDED DNA; SMALL TARGETS;

AMINES; DISEASES; ENERGY TRANSFER; ENZYMES; IONIC STRENGTH; MOLECULES; SCANNING; VIRUSES;

DNA;

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; SINGLE STRANDED DNA;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DEAMINATION; DNA DETERMINATION; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; IONIC STRENGTH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; SINGLE MOLECULE FORSTER RESONANCE ENERGY TRANSFER;

BACTERIOPHAGE M13; BASE SEQUENCE; BINDING SITES; BIOCATALYSIS; CYTIDINE DEAMINASE; DEAMINATION; DNA, SINGLE-STRANDED; DNA, VIRAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84860855710     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.342790     Document Type: Article

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