Anti-inflammatory IgG production requires functional P1 promoter in β-galactoside α2,6-sialyltransferase 1 (ST6Gal-1) gene

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15365-15370

  Jones, Mark B ^a   Nasirikenari, Mehrab ^a   Lugade, Amit A ^a   Thanavala, Yasmin ^a   Lau, Joseph T Y ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ,6-SIALYLTRANSFERASE; ACUTE-PHASE RESPONSE; ANTI-INFLAMMATORIES; B CELLS; BASE LINE; CHRONIC INFLAMMATION; EXTRACELLULAR; GLYCANS; IN-VIVO; INFLAMMATORY PROCESS; N-GLYCANS; NONTYPEABLE HAEMOPHILUS INFLUENZAE; OVALBUMINS; PROINFLAMMATORY; SIALIC ACIDS; SIALYLATION; SYSTEMIC CIRCULATION;

ANIMALS; CARBOXYLIC ACIDS; GENE EXPRESSION;

GLYCOSYLATION;

FC RECEPTOR; GLYCAN; IMMUNOGLOBULIN G; SIALIC ACID;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE SEVERITY; ENZYME SYNTHESIS; FUCOSYLATION; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIALYLATION; ST6GAL 1 GENE;

ACUTE-PHASE REACTION; ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-ACETYLNEURAMINIC ACID; OVALBUMIN; PNEUMONIA; POLYSACCHARIDES; PROMOTER REGIONS, GENETIC; SIALYLTRANSFERASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TURPENTINE;

ANIMALIA; HAEMOPHILUS INFLUENZAE;

EID: 84860848749     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.345710     Document Type: Article

References (29)

1. Bruhns, P., Samuelsson, A., Pollard, J. W., and Ravetch, J. V. (2003) Colony- stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 18, 573-581 (Pubitemid 36513638)
2. Samuelson, P. (2001) Anticircumvention rules: threat to science. Science 293, 2028-2031
3. - mouse model. Bone Marrow Transplantation 47, 439-450
4. Sokos, D. R., Berger, M., and Lazarus, H. M. (2002) Intravenous immunoglobulin: appropriate indications and uses in hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant. 8, 117-130 (Pubitemid 34285070)
5. Sullivan, K. M., Kopecky, K. J., Jocom, J., Fisher, L., Buckner, C. D., Meyers, J. D., Counts, G. W., Bowden, R. A., Peterson, F. B., and Witherspoon, R. P. (1990) Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation. N. Engl. J. Med. 323, 705-712 (Pubitemid 20288939)
6. Sullivan, K. M., Storek, J., Kopecky, K. J., Jocom, J., Longton, G., Flowers, M., Siadak, M., Nims, J., Witherspoon, R. P., Anasetti, C., Appelbaum, F. R., Bowden, R. A., Buckner, C. D., Crawford, S. W., Deeg, H. J., Hansen, J. A., McDonald, G. B., Sanders, J. E., and Storb, R. (1996) A controlled trial of long-term administration of intravenous immunoglobulin to prevent late infection and chronic graft-vs.-host disease after marrow transplantation: clinical outcome and effect on subsequent immune recovery. Biol. Blood Marrow Transplant. 2, 44-53 (Pubitemid 126488195)
7. H2 pathway. Nature 475, 110-113
8. Kaneko, Y., Nimmerjahn, F., and Ravetch, J. V. (2006) Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 313, 670-673 (Pubitemid 44201145)
9. Anthony, R. M., Wermeling, F., Karlsson, M. C., and Ravetch, J. V. (2008) Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc. Natl. Acad. Sci. U.S.A. 105, 19571-19578
10. Anthony, R. M., Nimmerjahn, F., Ashline, D. J., Reinhold, V. N., Paulson, J. C., and Ravetch, J. V. (2008) Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science 320, 373-376 (Pubitemid 351555659)
11. Nasirikenari, M., Chandrasekaran, E. V., Matta, K. L., Segal, B. H., Bogner, P. N., Lugade, A. A., Thanavala, Y., Lee, J. J., and Lau, J. T. (2010) Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation. J. Leukoc. Biol. 87, 457-466
12. Nasirikenari, M., Segal, B. H., Ostberg, J. R., Urbasic, A., and Lau, J. T. (2006) Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal-1. Blood 108, 3397-3405
13. Dalziel, M., Huang, R. Y., Dall'Olio, F., Morris, J. R., Taylor-Papadimitriou, J., and Lau, J. T. (2001) Mouse ST6Gal sialyltransferase gene expression during mammary gland lactation. Glycobiology 11, 407-412 (Pubitemid 32685214)
14. Wuensch, S. A., Huang, R. Y., Ewing, J., Liang, X., and Lau, J. T. (2000) Murine B cell differentiation is accompanied by programmed expression of multiple novel β-galactoside α2,6-sialyltransferase mRNA forms. Glycobiology 10, 67-75 (Pubitemid 30122201)
15. Hu, Y. P., Dalziel, M., and Lau, J. T. (1997) Murine hepatic β-galactoside α2,6-sialyltransferase gene expression involves usage of a novel upstream exon region. Glycoconj. J. 14, 407-411 (Pubitemid 27231682)
16. Jones, M. B., Nasirikenari, M., Feng, L., Migliore, M. T., Choi, K. S., Kazim, L., and Lau, J. T. (2010) Role for hepatic and circulatory ST6Gal-1 sialyl-transferase in regulating myelopoiesis. J. Biol. Chem. 285, 25009-25017
17. Appenheimer, M. M., Huang, R. Y., Chandrasekaran, E. V., Dalziel, M., Hu, Y. P., Soloway, P. D., Wuensch, S. A., Matta, K. L., and Lau, J. T. (2003) Biologic contribution of P1 promoter-mediated expression of ST6Gal-1 sialyltransferase. Glycobiology 13, 591-600 (Pubitemid 36939575)
18. Hennet, T., Chui, D., Paulson, J. C., and Marth, J. D. (1998) Immune regulation by the ST6Gal sialyltransferase. Proc. Natl. Acad. Sci. U.S.A. 95, 4504-4509 (Pubitemid 128620781)
19. Lugade, A. A., Vethanayagam, R. R., Nasirikenari, M., Bogner, P. N., Segal, B. H., and Thanavala, Y. (2011) Nrf2 regulates chronic lung inflammation and B cell responses to nontypeable Haemophilus influenzae. Am. J. Respir. Cell Mol. Biol. 45, 557-565
20. Lugade, A. A., Bogner, P. N., Murphy, T. F., and Thanavala, Y. (2011) The role of TLR2 and bacterial lipoprotein in enhancing airway inflammation and immunity. Front. Immun. 2, 10
21. Lugade, A. A., Bogner, P. N., and Thanavala, Y. (2011) Murine model of chronic respiratory inflammation. Adv. Exp. Med. Biol. 780, 125-141
22. Murphy, T. F. (2003) Respiratory infections caused by nontypeable Haemophilus influenzae. Curr. Opin. Infect. Dis. 16, 129-134
23. Martin, L. T., Marth, J. D., Varki, A., and Varki, N. M. (2002) Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation. J. Biol. Chem. 277, 32930-32938 (Pubitemid 34987555)
24. Blomme, B., Van Steenkiste, C., Grassi, P., Haslam, S. M., Dell, A., Callewaert, N., and Van Vlierberghe, H. (2011) Alterations of serum protein N-glycosylation in two mouse models of chronic liver disease are hepatocyte and not B cell-driven. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G833-F842
25. Baumann, H., and Gauldie, J. (1994) The acute phase response. Immunol. Today 15, 74-80 (Pubitemid 24049800)
26. Kötz, K., Hänsler, M., Sauer, H., Kaltenhäuser, S., and Häntzschel, H. (1996) Immunoglobulin G galactosylation deficiency determined by iso-electric focusing and lectin affinoblotting in differential diagnosis of rheumatoid arthritis. Electrophoresis 17, 533-534
27. van de Geijn, F. E., Wuhrer, M., Selman, M. H., Willemsen, S. P., de Man, Y. A., Deelder, A. M., Hazes, J. M., and Dolhain, R. J. (2009) Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study. Arthritis Res. Ther. 11, R193
28. Stadlmann, J., Weber, A., Pabst, M., Anderle, H., Kunert, R., Ehrlich, H. J., Peter Schwarz, H., and Altmann, F. (2009) A close look at human IgG sialylation and subclass distribution after lectin fractionation. Proteomics 9, 4143-4153
29. Stadlmann, J., Pabst, M., and Altmann, F. (2010) Analytical and functional aspects of antibody sialylation. J. Clin. Immunol. 30, Suppl. 1, 15-19