TGF-beta 1/Smad3 expression and its effects on carotid intimal hyperplasia

Frontiers in Bioscience - Elite

Volumn 4 E, Issue 6, 2012, Pages 2022-2028

  Lu, Ping ^a   Wang, Songhao ^a   Cai, Wenwei ^a   Sheng, Jing ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Adenovirus; Antisense Smad3; Balloon injury; Intimal hyperplasia; TGF beta 1 Stand3 signaling pathway

Indexed keywords

ADENOVIRUS VECTOR; CYCLINE; KI 67 ANTIGEN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NEOINTIMA; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; CAROTID ARTERY; DISEASE MODEL; HYPERPLASIA; INTIMA; METABOLISM; PATHOLOGY;

ADENOVIRIDAE; RATTUS;

ANIMALS; CAROTID ARTERIES; DISEASE MODELS, ANIMAL; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; REAL-TIME POLYMERASE CHAIN REACTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUNICA INTIMA;

EID: 84860847341     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T: Heart disease and stroke statistics-2006 update: a report fromthe American Heart Association Statistics Committee and StrokesStatistics Subcommittee. Circulation 113, e85-e151 (2006))
2. Babapulle MN, Joseph L, Belisle P, Brophy JM, Eisenberg MJ: Ahierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents. Lancet 364, 583-91 (2004)) (Pubitemid 39094175)
3. Mitra AK, Agrawal DK: In stent restenosis: bane of the stent era. J Clin Pathol 59, 232-9 (2006)) (Pubitemid 43344881)
4. Newby AC, Zaltsman AB: Molecular mechanisms in intimal hyperplasia. J Pathol 190, 300-9 (2000)) (Pubitemid 30141376)
5. Ollinger R, Bilban M, Erat A: Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation. Circulation 112, 1030-9 (2005))
6. Mallat Z, Tedgni A: The role of transforming growth factor beta in atheroselerosis:novel insights and future perspectives.Curr Opin Lipidol 13(5), 523-9 (2002)) (Pubitemid 35231932)
7. Welt FG, Tso C, Edelman ER: Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vasc Med, 8(1):1-7 (2003)) (Pubitemid 36781066)
8. Dabek J, Kulach A, Monastyrska-Cup B: Transforminggrowth factor beta and cardiovascular diseases:the other facet of the " protective cytokine". Pharmacol Re p 58(6):799-805 (2006))
9. Nikol S, Isner JM, Pickering JG, Kearney M, Leclerc G, Weir L: Expression of transforming growth factor-beta 1 is increased in human vascular restenosis lesions. J Clin Invest 90: 1582-1592 (1992))
10. Ryan ST, Koteliansky VE, Gotwals PJ, Lindner V: Transforming growth factor-beta-dependent events in vascular remodeling following arterial injury. J Vasc Res 40: 37-46 (2003)) (Pubitemid 36351194)
11. Bobik A. Transforming growth factor-betas and vascular disorders. Arterioscler Thromb Vasc Biol 26, 1712-20 2006;; (Pubitemid 44305323)
12. Kanzaki T, Tamura K, Takahashi K, Saito Y, Akikusa B, Oohashi H, Kasayuki N, Ueda M, Morisaki N: In vivo effect of TGF-beta 1. Enhanced intimal thickening by administration of TGF- beta 1 in rabbit arteries injured with a balloon catheter. Arterioscler Thromb Vasc Biol 15, 1951-1957 (1995))
13. Ward MR, Agrotis A, Kanellakis P, Hall J, Jennings G, Bobik A: Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting. Arterioscler Thromb Vasc Biol 22, 940-8 (2002)) (Pubitemid 34655221)
14. Merrilees M, Beaumont B, Scott L, Hermanutz V, Fennessy P: Effect of TGF-beta(1) antisense Soligonucleotide on synthesis and accumulation of matrix proteoglycans in balloon catheter-injured neointima of rabbit carotid arteries. J Vasc Res 37, 50-60 (2000)) (Pubitemid 30158041)
15. Ryer EJ, Hom RP, Sakakibara K, Nakayama KI, Nakayama K, Faries PL, Liu B, Kent KC. PKCdelta is necessary for Smad3 expression and transforming growth factor beta-induced fibronectin synthesis in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 26, 780-6 (2006)) (Pubitemid 43732151)
16. Wu juanjuan, Wang danru, Lu hongjun: Establishment of inverse smad3 vector and expression in vitro. Magazine of shanghai second medical university 4(8), 600-2 (2004))
17. Tsai S, Hollenbeck ST, Ryer EJ: TGF-{beta}through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation. Am J Physiol Heart Circ Physiol 297(2), H540-9 (2009))
18. Meyer C, Meindl-Beinker NM, Dooley S: TGF-beta signaling in alcohol induced hepatic injury. Front Biosci 15, 740-9 (2010))
19. Reiner JE, Datta PK: TGF-beta-dependent and - independent roles of STRAP in cancer. Front Biosci 16, 105-15 (2011))
20. Smith JD, Bryant SR, Couper LL: Soluble Transforming growth factor. beta type II receptor inhibits negative remodeling,fibroblast transdiferentiation,and intimal lesion form ation but not endothelial growth. Circ Res, 84(10), 1212-22 (1999)) (Pubitemid 29244783)
21. Yamamoto K, Morishita R, Tomita N: Ribozyme oligonucleo. tides against transforming growth factor-13 inhibited neointimal formation after vascular injury in rat model. Circulation 102 (11), 1308-14 (2000))