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Volumn 1, Issue 1, 2011, Pages 143-152

Exocytosis from pancreatic β-cells: Mathematical modelling of the exit of low-molecular-weight granule content

Author keywords

Exocytosis; Insulin; Kiss and run; Mathematical modelling; Pancreas

Indexed keywords


EID: 84860846205     PISSN: 20428898     EISSN: 20428901     Source Type: Journal    
DOI: 10.1098/rsfs.2010.0006     Document Type: Article
Times cited : (16)

References (38)
  • 1
    • 1842579441 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus: Not quite exciting enough?
    • Ashcroft, F. & Rorsman, P. 2004 Type 2 diabetes mellitus: not quite exciting enough? Hum. Mol. Genet. 13, R21-R31.
    • (2004) Hum. Mol. Genet. , vol.13
    • Ashcroft, F.1    Rorsman, P.2
  • 2
    • 0024917106 scopus 로고
    • Electrophysiology of the pancreatic beta-cell
    • (doi:10.1016/0079-6107(89)90013-8)
    • Ashcroft, F. M. & Rorsman, P. 1989 Electrophysiology of the pancreatic beta-cell. Prog. Biophys. Mol. Biol. 54, 87-143. (doi:10.1016/0079-6107(89)90013-8)
    • (1989) Prog. Biophys. Mol. Biol. , vol.54 , pp. 87-143
    • Ashcroft, F.M.1    Rorsman, P.2
  • 4
    • 0015610440 scopus 로고
    • Ultrastructural morphometry of the pancreatic β-cell
    • (doi:10.1007/BF01230690)
    • Dean, P. M. 1973 Ultrastructural morphometry of the pancreatic β-cell. Diabetologia 9, 115-119. (doi:10.1007/BF01230690)
    • (1973) Diabetologia , vol.9 , pp. 115-119
    • Dean, P.M.1
  • 5
    • 0036261251 scopus 로고    scopus 로고
    • Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic β-cells
    • (doi:10.1007/s00424-002-0781-5)
    • Olofsson, C. S., Gopel, S. O., Barg, S., Galvanovskis, J., Ma, X., Salehi, A., Rorsman, P. & Eliasson, L. 2002 Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic β-cells. Pflugers Arch. 444, 43-51. (doi:10.1007/s00424-002-0781-5)
    • (2002) Pflugers Arch. , vol.444 , pp. 43-51
    • Olofsson, C.S.1    Gopel, S.O.2    Barg, S.3    Galvanovskis, J.4    Ma, X.5    Salehi, A.6    Rorsman, P.7    Eliasson, L.8
  • 6
    • 0042879951 scopus 로고    scopus 로고
    • Insulin granule dynamics in pancreatic β-cells
    • (doi:10.1007/s00125-003-1153-1)
    • Rorsman, P. & Renstrom, E. 2003 Insulin granule dynamics in pancreatic β-cells. Diabetologia 46, 1029-1045. (doi:10.1007/s00125-003-1153-1)
    • (2003) Diabetologia , vol.46 , pp. 1029-1045
    • Rorsman, P.1    Renstrom, E.2
  • 7
    • 0037380131 scopus 로고    scopus 로고
    • Multiple forms of 'kissand-run' exocytosis revealed by evanescent wave microscopy
    • (doi:10.1016/S0960-9822(03)00176-3)
    • Tsuboi, T. & Rutter, G. A. 2003 Multiple forms of 'kissand-run' exocytosis revealed by evanescent wave microscopy. Curr. Biol. 13, 563-567. (doi:10.1016/S0960-9822(03)00176-3)
    • (2003) Curr. Biol. , vol.13 , pp. 563-567
    • Tsuboi, T.1    Rutter, G.A.2
  • 8
    • 0020581761 scopus 로고
    • Lowmolecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphate
    • Hutton, J. C., Penn, E. J. & Peshavaria, M. 1983 Lowmolecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphate. Biochem. J. 210, 297-305.
    • (1983) Biochem. J. , vol.210 , pp. 297-305
    • Hutton, J.C.1    Penn, E.J.2    Peshavaria, M.3
  • 9
    • 33751163058 scopus 로고    scopus 로고
    • Mechanisms of peptide hormone secretion
    • (doi:10.1016/j. tem.2006.10.011)
    • Michael, D. J., Cai, H., Xiong, W., Ouyang, J. & Chow, R. H. 2006 Mechanisms of peptide hormone secretion. Trends Endocrinol. Metab. 17, 408-415. (doi:10.1016/j. tem.2006.10.011)
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 408-415
    • Michael, D.J.1    Cai, H.2    Xiong, W.3    Ouyang, J.4    Chow, R.H.5
  • 10
    • 77954252193 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells
    • (doi:10.2337/db09-0797)
    • Braun, M., Ramracheya, R., Bengtsson, M., Clark, A., Walker, J. N., Johnson, P. R. & Rorsman, P. 2010 Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. Diabetes 59, 1694-1701. (doi:10.2337/db09-0797)
    • (2010) Diabetes , vol.59 , pp. 1694-1701
    • Braun, M.1    Ramracheya, R.2    Bengtsson, M.3    Clark, A.4    Walker, J.N.5    Johnson, P.R.6    Rorsman, P.7
  • 11
    • 77950885567 scopus 로고    scopus 로고
    • ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell
    • (doi:10.1073/pnas. 0908935107)
    • Jacques-Silva, M. C. et al. 2010 ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell. Proc. Natl Acad. Sci. USA 107, 6465-6470. (doi:10.1073/pnas. 0908935107)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 6465-6470
    • Jacques-Silva, M.C.1
  • 12
    • 67349092443 scopus 로고    scopus 로고
    • Quantal ATP release in rat betacells by exocytosis of insulin-containing LDCVs
    • (doi:10.1007/s00424-008-0610-6)
    • Karanauskaite, J., Hoppa, M. B., Braun, M., Galvanovskis, J. & Rorsman, P. 2009 Quantal ATP release in rat betacells by exocytosis of insulin-containing LDCVs. Pflugers Arch. 458, 389-401. (doi:10.1007/s00424-008-0610-6)
    • (2009) Pflugers Arch. , vol.458 , pp. 389-401
    • Karanauskaite, J.1    Hoppa, M.B.2    Braun, M.3    Galvanovskis, J.4    Rorsman, P.5
  • 13
    • 33847342070 scopus 로고    scopus 로고
    • Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic β-cells
    • (doi:10.1085/jgp. 200609658)
    • Braun, M., Wendt, A., Karanauskaite, J., Galvanovskis, J., Clark, A., MacDonald, P. E. & Rorsman, P. 2007 Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic β-cells. J. Gen. Physiol. 129, 221-231. (doi:10.1085/jgp. 200609658)
    • (2007) J. Gen. Physiol. , vol.129 , pp. 221-231
    • Braun, M.1    Wendt, A.2    Karanauskaite, J.3    Galvanovskis, J.4    Clark, A.5    McDonald, P.E.6    Rorsman, P.7
  • 14
    • 27144434554 scopus 로고    scopus 로고
    • Selective nucleotide-release from dense-core granules in insulinsecreting cells
    • (doi:10. 1242/jcs.02549)
    • Obermuller, S., Lindqvist, A., Karanauskaite, J., Galvanovskis, J., Rorsman, P. & Barg, S. 2005 Selective nucleotide-release from dense-core granules in insulinsecreting cells. J. Cell Sci. 118, 4271-4282. (doi:10. 1242/jcs.02549)
    • (2005) J. Cell Sci. , vol.118 , pp. 4271-4282
    • Obermuller, S.1    Lindqvist, A.2    Karanauskaite, J.3    Galvanovskis, J.4    Rorsman, P.5    Barg, S.6
  • 15
    • 2942527205 scopus 로고    scopus 로고
    • FMRFamide tagging-how an ionotropic receptor can be used to measure peptide secretion
    • (doi:10.1016/j.ymeth. 2004.01.007)
    • Whim, M. D. & Moss, G. W. 2004 FMRFamide tagging-how an ionotropic receptor can be used to measure peptide secretion. Methods 33, 295-301. (doi:10.1016/j.ymeth. 2004.01.007)
    • (2004) Methods , vol.33 , pp. 295-301
    • Whim, M.D.1    Moss, G.W.2
  • 16
    • 0031919679 scopus 로고    scopus 로고
    • Comparison of secretory responses as measured by membrane capacitance and by amperometry
    • (doi:10.1016/S0006-3495(98)77917-2)
    • Haller, M., Heinemann, C., Chow, R. H., Heidelberger, R. & Neher, E. 1998 Comparison of secretory responses as measured by membrane capacitance and by amperometry. Biophys. J. 74, 2100-2113. (doi:10.1016/S0006-3495(98)77917-2)
    • (1998) Biophys. J. , vol.74 , pp. 2100-2113
    • Haller, M.1    Heinemann, C.2    Chow, R.H.3    Heidelberger, R.4    Neher, E.5
  • 17
    • 0028863731 scopus 로고
    • A fluorimetric and amperometric study of calcium and secretion in isolated mouse pancreatic β-cells
    • (doi:10.1007/BF00386180)
    • Smith, P. A., Duchen, M. R. & Ashcroft, F. M. 1995 A fluorimetric and amperometric study of calcium and secretion in isolated mouse pancreatic β-cells. Pflugers Arch. 430, 808-818. (doi:10.1007/BF00386180)
    • (1995) Pflugers Arch. , vol.430 , pp. 808-818
    • Smith, P.A.1    Duchen, M.R.2    Ashcroft, F.M.3
  • 18
    • 0015134317 scopus 로고
    • Monoamines in the pancreatic islets of the mouse. Subcellular localization of 5-hydroxytryptamine by electron microscopic autoradiography
    • (doi:10.1007/BF01219468)
    • Ekholm, R., Ericson, L. E. & Lundquist, I. 1971 Monoamines in the pancreatic islets of the mouse. Subcellular localization of 5-hydroxytryptamine by electron microscopic autoradiography. Diabetologia 7, 339-348. (doi:10.1007/BF01219468)
    • (1971) Diabetologia , vol.7 , pp. 339-348
    • Ekholm, R.1    Ericson, L.E.2    Lundquist, I.3
  • 19
    • 0020957897 scopus 로고
    • 5-Hydroxytryptamine transport in cells and secretory granules from a transplantable rat insulinoma
    • Hutton, J. C., Peshavaria, M. & Tooke, N. E. 1983 5-Hydroxytryptamine transport in cells and secretory granules from a transplantable rat insulinoma. Biochem. J. 210, 803-810.
    • (1983) Biochem. J. , vol.210 , pp. 803-810
    • Hutton, J.C.1    Peshavaria, M.2    Tooke, N.E.3
  • 20
    • 33748946239 scopus 로고    scopus 로고
    • Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β-cells
    • (doi:10.1016/j.cmet.2006.08.011)
    • MacDonald, P. E., Braun, M., Galvanovskis, J. & Rorsman, P. 2006 Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β-cells. Cell Metab. 4, 283-290. (doi:10.1016/j.cmet.2006.08.011)
    • (2006) Cell Metab. , vol.4 , pp. 283-290
    • McDonald, P.E.1    Braun, M.2    Galvanovskis, J.3    Rorsman, P.4
  • 21
    • 0030739061 scopus 로고    scopus 로고
    • Multiple exocytotic pathways in pancreatic β-cells
    • (doi:10.1083/jcb.138.1.55)
    • Takahashi, N., Kadowaki, T., Yazaki, Y., Miyashita, Y. & Kasai, H. 1997 Multiple exocytotic pathways in pancreatic β-cells. J. Cell Biol. 138, 55-64. (doi:10.1083/jcb.138.1.55)
    • (1997) J. Cell Biol. , vol.138 , pp. 55-64
    • Takahashi, N.1    Kadowaki, T.2    Yazaki, Y.3    Miyashita, Y.4    Kasai, H.5
  • 22
    • 0141600640 scopus 로고    scopus 로고
    • Compound exocytosis in voltage-clamped mouse pancreatic β-cells revealed by carbon fibre amperometry
    • (doi:10.1007/s00424005 0987)
    • Bokvist, K., Holmqvist, M., Gromada, J. & Rorsman, P. 2000 Compound exocytosis in voltage-clamped mouse pancreatic β-cells revealed by carbon fibre amperometry. Pflugers Arch. 439, 634-645. (doi:10.1007/s00424005 0987)
    • (2000) Pflugers Arch. , vol.439 , pp. 634-645
    • Bokvist, K.1    Holmqvist, M.2    Gromada, J.3    Rorsman, P.4
  • 23
    • 0025875235 scopus 로고
    • GABA and pancreatic β-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
    • Reetz, A., Solimena, M., Matteoli, M., Folli, F., Takei, K. & De Camilli, P. 1991 GABA and pancreatic β-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J. 10, 1275-1284.
    • (1991) EMBO J. , vol.10 , pp. 1275-1284
    • Reetz, A.1    Solimena, M.2    Matteoli, M.3    Folli, F.4    Takei, K.5    de Camilli, P.6
  • 24
    • 27844539359 scopus 로고    scopus 로고
    • Exocytosis and endocytosis of small vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis
    • (doi:10.1113/jphysiol.2005.094011)
    • Liu, T. T., Kishimoto, T., Hatakeyama, H., Nemoto, T., Takahashi, N. & Kasai, H. 2005 Exocytosis and endocytosis of small vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis. J. Physiol. 568, 917-929. (doi:10.1113/jphysiol.2005.094011)
    • (2005) J. Physiol. , vol.568 , pp. 917-929
    • Liu, T.T.1    Kishimoto, T.2    Hatakeyama, H.3    Nemoto, T.4    Takahashi, N.5    Kasai, H.6
  • 25
    • 0030768802 scopus 로고    scopus 로고
    • The exocytotic event in chromaffin cells revealed by patch amperometry
    • (doi:10.1038/39081)
    • Albillos, A., Dernick, G., Horstmann, H., Almers, W., Alvarez de Toledo, G. & Lindau, M. 1997 The exocytotic event in chromaffin cells revealed by patch amperometry. Nature 389, 509-512. (doi:10.1038/39081)
    • (1997) Nature , vol.389 , pp. 509-512
    • Albillos, A.1    Dernick, G.2    Horstmann, H.3    Almers, W.4    Alvarez de Toledo, G.5    Lindau, M.6
  • 26
    • 0037122871 scopus 로고    scopus 로고
    • Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells
    • (doi:10.1016/S0896-6273(02)00563-9)
    • Barg, S., Olofsson, C. S., Schriever-Abeln, J., Wendt, A., Gebre-Madhin, S., Renström, E. & Rorsman, P. 2002 Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells. Neuron 33, 287-299. (doi:10.1016/S0896-6273(02)00563-9)
    • (2002) Neuron , vol.33 , pp. 287-299
    • Barg, S.1    Olofsson, C.S.2    Schriever-Abeln, J.3    Wendt, A.4    Gebre-Madhin, S.5    Renström, E.6    Rorsman, P.7
  • 27
    • 0027516245 scopus 로고
    • The secretory granule matrix: A fast-acting smart polymer
    • (doi:10.1126/science.8438154)
    • Nanavati, C. & Fernandez, J. M. 1993 The secretory granule matrix: a fast-acting smart polymer. Science 259, 963-965. (doi:10.1126/science.8438154)
    • (1993) Science , vol.259 , pp. 963-965
    • Nanavati, C.1    Fernandez, J.M.2
  • 28
    • 0037162886 scopus 로고    scopus 로고
    • Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet
    • (doi:10.1126/science.1073806)
    • Takahashi, N., Kishimoto, T., Nemoto, T., Kadowaki, T. & Kasai, H. 2002 Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet. Science 297, 1349-1352. (doi:10.1126/science.1073806)
    • (2002) Science , vol.297 , pp. 1349-1352
    • Takahashi, N.1    Kishimoto, T.2    Nemoto, T.3    Kadowaki, T.4    Kasai, H.5
  • 29
    • 0028973129 scopus 로고
    • Rapid desensitization of a 1 b 1 GABA A receptors expressed in Sf9 cells under optimized conditions
    • Birnir, B., Tierney, M. L., Pillai, N. P., Cox, G. B. & Gage, P. W. 1995 Rapid desensitization of a 1 b 1 GABA A receptors expressed in Sf9 cells under optimized conditions. J. Membr. Biol. 148, 193-202.
    • (1995) J. Membr. Biol. , vol.148 , pp. 193-202
    • Birnir, B.1    Tierney, M.L.2    Pillai, N.P.3    Cox, G.B.4    Gage, P.W.5
  • 31
    • 0032940264 scopus 로고    scopus 로고
    • Single channel properties of P2X2 purinoceptors
    • (doi:10.1085/jgp.113.5.695)
    • Ding, S. & Sachs, F. 1999 Single channel properties of P2X2 purinoceptors. J. Gen. Physiol. 113, 695-720. (doi:10.1085/jgp.113.5.695)
    • (1999) J. Gen. Physiol. , vol.113 , pp. 695-720
    • Ding, S.1    Sachs, F.2
  • 33
    • 0016661064 scopus 로고
    • Adenine nucleotides in the secretory granule fraction of rat islets
    • Leitner, J. W., Sussman, K. E., Vatter, A. E. & Schneider, F. H. 1975 Adenine nucleotides in the secretory granule fraction of rat islets. Endocrinology 96, 662-677.
    • (1975) Endocrinology , vol.96 , pp. 662-677
    • Leitner, J.W.1    Sussman, K.E.2    Vatter, A.E.3    Schneider, F.H.4
  • 34
    • 0032545293 scopus 로고    scopus 로고
    • The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in β-cells but not in alpha cells and are also observed in human islets
    • (doi:10.1074/jbc.273.51.33905)
    • Detimary, P., Dejonghe, S., Ling, Z., Pipeleers, D., Schuit, F. & Henquin, J. C. 1998 The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in β-cells but not in alpha cells and are also observed in human islets. J. Biol. Chem. 273, 33 905-33 908. (doi:10.1074/jbc.273.51.33905)
    • (1998) J. Biol. Chem. , vol.273 , pp. 33905-33908
    • Detimary, P.1    Dejonghe, S.2    Ling, Z.3    Pipeleers, D.4    Schuit, F.5    Henquin, J.C.6
  • 35
    • 0029833117 scopus 로고    scopus 로고
    • Stable and diffusible pools of nucleotides in pancreatic islet cells
    • (doi:10.1210/en.137.11.4671)
    • Detimary, P., Jonas, J. C. & Henquin, J. C. 1996 Stable and diffusible pools of nucleotides in pancreatic islet cells. Endocrinology 137, 4671-4676. (doi:10.1210/en.137.11.4671)
    • (1996) Endocrinology , vol.137 , pp. 4671-4676
    • Detimary, P.1    Jonas, J.C.2    Henquin, J.C.3
  • 37
    • 21344449293 scopus 로고    scopus 로고
    • Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility
    • (doi:10.2337/diabetes.54.7.2126)
    • Salehi, A., Qader, S. S., Grapengiesser, E. & Hellman, B. 2005 Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility. Diabetes 54, 2126-2131. (doi:10.2337/diabetes.54.7.2126)
    • (2005) Diabetes , vol.54 , pp. 2126-2131
    • Salehi, A.1    Qader, S.S.2    Grapengiesser, E.3    Hellman, B.4
  • 38
    • 1842422955 scopus 로고    scopus 로고
    • Glucose inhibition of glucagon secretion from rat α-cells is mediated by GABA released from neighboring bβ-cells
    • (doi:10.2337/diabetes.53.4.1038)
    • Wendt, A., Birnir, B., Buschard, K., Gromada, J., Salehi, A., Sewing, S., Rorsman, P. & Braun, M. 2004 Glucose inhibition of glucagon secretion from rat α-cells is mediated by GABA released from neighboring β-cells. Diabetes 53, 1038-1045. (doi:10.2337/diabetes.53.4.1038)
    • (2004) Diabetes , vol.53 , pp. 1038-1045
    • Wendt, A.1    Birnir, B.2    Buschard, K.3    Gromada, J.4    Salehi, A.5    Sewing, S.6    Rorsman, P.7    Braun, M.8


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