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Volumn 444, Issue 1, 2012, Pages 105-114

MEF2 is regulated by CaMKIIδ2 and a HDAC4-HDAC5 heterodimer in vascular smooth muscle cells

Author keywords

Ca2+ calmodulin dependent protein kinase II (CaMKII); Gene transcription; Histone deacetylase (HDAC); Myocyte enhancer factor 2 (MEF2); Vascular smooth muscle cell (VSMC)

Indexed keywords

ANGIOTENSIN II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DNA; HISTONE DEACETYLASE; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; IONOMYCIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOCYTE ENHANCER FACTOR 2; NUCLEAR RECEPTOR NUR77; PLATELET DERIVED GROWTH FACTOR; POLYCLONAL ANTIBODY; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

EID: 84860797875     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120152     Document Type: Article
Times cited : (49)

References (55)
  • 1
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • DOI 10.1152/physrev.00041.2003
    • Owens, G. K., Kumar, M. S. and Wamhoff, B. R. (2004) Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol. Rev. 84, 767-801 (Pubitemid 38823766)
    • (2004) Physiological Reviews , vol.84 , Issue.3 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 2
    • 0034781921 scopus 로고    scopus 로고
    • 2+ and growth signals
    • DOI 10.1046/j.1365-201X.2001.00873.x
    • Lindqvist, A., Nilsson, B. O., Ekblad, E. and Hellstrand, P. (2001) Platelet-derived growth factor receptors expressed in response to injury of differentiated vascular smooth muscle in vitro: effects on Ca2+ and growth signals. Acta Physiol. Scand. 173, 175-184 (Pubitemid 32989450)
    • (2001) Acta Physiologica Scandinavica , vol.173 , Issue.2 , pp. 175-184
    • Lindqvist, A.1    Nilsson, B.-O.2    Ekblad, E.3    Hellstrand, P.4
  • 3
    • 0031898438 scopus 로고    scopus 로고
    • L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells
    • Gollasch, M., Haase, H., Ried, C., Lindschau, C., Morano, I., Luft, F. C. and Haller, H. (1998) L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells. FASEB J. 12, 593-601 (Pubitemid 28183518)
    • (1998) FASEB Journal , vol.12 , Issue.7 , pp. 593-601
    • Gollasch, M.1    Haase, H.2    Ried, C.3    Lindschau, C.4    Morano, I.5    Luft, F.C.6    Haller, H.7
  • 6
    • 33747624445 scopus 로고    scopus 로고
    • Transient receptor potential channels in cardiovascular function and disease
    • DOI 10.1161/01.RES.0000233356.10630.8a, PII 0000301220060721000005
    • Inoue, R., Jensen, L. J., Shi, J., Morita, H., Nishida, M., Honda, A. and Ito, Y. (2006) Transient receptor potential channels in cardiovascular function and disease. Circ. Res. 99, 119-131 (Pubitemid 44297035)
    • (2006) Circulation Research , vol.99 , Issue.2 , pp. 119-131
    • Inoue, R.1    Jensen, L.J.2    Shi, J.3    Morita, H.4    Nishida, M.5    Honda, A.6    Ito, Y.7
  • 7
    • 33646124716 scopus 로고    scopus 로고
    • Excitation-transcription coupling in arterial smooth muscle
    • Wamhoff, B. R., Bowles, D. K. and Owens, G. K. (2006) Excitation-transcription coupling in arterial smooth muscle. Circ. Res. 98, 868-878
    • (2006) Circ. Res. , vol.98 , pp. 868-878
    • Wamhoff, B.R.1    Bowles, D.K.2    Owens, G.K.3
  • 9
    • 40749153151 scopus 로고    scopus 로고
    • CaMKII-δ isoform regulation of neointima formation after vascular injury
    • House, S. J. and Singer, H. A. (2008) CaMKII-δ isoform regulation of neointima formation after vascular injury. Arterioscler. Thromb. Vasc. Biol. 28, 441-447
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 441-447
    • House, S.J.1    Singer, H.A.2
  • 10
    • 0034111687 scopus 로고    scopus 로고
    • Inhibition of CaM kinase II activation and force maintenance by KN-93 in arterial smooth muscle
    • Rokolya, A. and Singer, H. A. (2000) Inhibition of CaM kinase II activation and force maintenance by KN-93 in arterial smooth muscle. Am. J. Physiol. Cell Physiol. 278, C537-C545 (Pubitemid 30154933)
    • (2000) American Journal of Physiology - Cell Physiology , vol.278 , Issue.3
    • Rokolya, A.1    Singer, H.A.2
  • 11
    • 79953149132 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinase IIδ(CaMKIIδ) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21
    • 2+/calmodulin-dependent kinase IIδ(CaMKIIδ) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21. J. Biol. Chem. 286, 7990-7999
    • (2011) J. Biol. Chem. , vol.286 , pp. 7990-7999
    • Li, W.1    Li, H.2    Sanders, P.N.3    Mohler, P.J.4    Backs, J.5    Olson, E.N.6    Anderson, M.E.7    Grumbach, I.M.8
  • 14
    • 33745133033 scopus 로고    scopus 로고
    • MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field
    • DOI 10.1002/dvdy.20828
    • Vong, L., Bi, W., O'Connor-Halligan, K. E., Li, C., Cserjesi, P. and Schwarz, J. J. (2006) MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field. Dev. Dyn. 235, 1809-1821 (Pubitemid 43902340)
    • (2006) Developmental Dynamics , vol.235 , Issue.7 , pp. 1809-1821
    • Vong, L.1    Bi, W.2    O'Connor-Halligan, K.E.3    Li, C.4    Cserjesi, P.5    Schwarz, J.J.6
  • 15
    • 0036851837 scopus 로고    scopus 로고
    • Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
    • DOI 10.1038/nm789
    • Naya, F. J., Black, B. L., Wu, H., Bassel-Duby, R., Richardson, J. A., Hill, J. A. and Olson, E. N. (2002) Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat. Med. 8, 1303-1309 (Pubitemid 35373564)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1303-1309
    • Naya, F.J.1    Black, B.L.2    Wu, H.3    Bassel-Duby, R.4    Richardson, J.A.5    Hill, J.A.6    Olson, E.N.7
  • 17
    • 14244264689 scopus 로고    scopus 로고
    • Mef2c is activated directly by Ets transcription factors through an evolutionarily conserved endothelial cell-specific enhancer
    • DOI 10.1016/j.ydbio.2004.08.016
    • De Val, S., Anderson, J. P., Heidt, A. B., Khiem, D., Xu, S. M. and Black, B. L. (2004) Mef2c is activated directly by Ets transcription factors through an evolutionarily conserved endothelial cell-specific enhancer. Dev. Biol. 275, 424-434 (Pubitemid 40288096)
    • (2004) Developmental Biology , vol.275 , Issue.2 , pp. 424-434
    • De Val, S.1    Anderson, J.P.2    Heidt, A.B.3    Khiem, D.4    Xu, S.-M.5    Black, B.L.6
  • 18
    • 38049147787 scopus 로고    scopus 로고
    • MEF2: A central regulator of diverse developmental programs
    • Potthoff, M. J. and Olson, E. N. (2007) MEF2: a central regulator of diverse developmental programs. Development 134, 4131-4140
    • (2007) Development , vol.134 , pp. 4131-4140
    • Potthoff, M.J.1    Olson, E.N.2
  • 19
    • 1942453894 scopus 로고    scopus 로고
    • HRC Is a Direct Transcriptional Target of MEF2 during Cardiac, Skeletal, and Arterial Smooth Muscle Development In Vivo
    • DOI 10.1128/MCB.24.9.3757-3768.2004
    • Anderson, J. P., Dodou, E., Heidt, A. B., De Val, S. J., Jaehnig, E. J., Greene, S. B., Olson, E. N. and Black, B. L. (2004) HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo. Mol. Cell. Biol. 24, 3757-3768 (Pubitemid 38496155)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.9 , pp. 3757-3768
    • Anderson, J.P.1    Dodou, E.2    Heidt, A.B.3    De Val, S.J.4    Jaehnig, E.J.5    Greene, S.B.6    Olson, E.N.7    Black, B.L.8
  • 20
    • 33751534932 scopus 로고    scopus 로고
    • Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development
    • DOI 10.1242/dev.02610
    • Creemers, E. E., Sutherland, L. B., McAnally, J., Richardson, J. A. and Olson, E. N. (2006) Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development. Development 133, 4245-4256 (Pubitemid 44830668)
    • (2006) Development , vol.133 , Issue.21 , pp. 4245-4256
    • Creemers, E.E.1    Sutherland, L.B.2    McAnally, J.3    Richardson, J.A.4    Olson, E.N.5
  • 21
    • 0030049945 scopus 로고    scopus 로고
    • Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells: Association with the activated phenotype
    • Firulli, A. B., Miano, J. M., Bi, W., Johnson, A. D., Casscells, W., Olson, E. N. and Schwarz, J. J. (1996) Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells: association with the activated phenotype. Circ. Res. 78, 196-204 (Pubitemid 26042838)
    • (1996) Circulation Research , vol.78 , Issue.2 , pp. 196-204
    • Firulli, A.B.1    Miano, J.M.2    Bi, W.3    Johnson, A.D.4    Casscells, W.5    Olson, E.N.6    Schwarz, J.J.7
  • 22
    • 0029002558 scopus 로고
    • Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation
    • Suzuki, E., Guo, K., Kolman, M., Yu, Y. T. and Walsh, K. (1995) Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation. Mol. Cell. Biol. 15, 3415-3423
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3415-3423
    • Suzuki, E.1    Guo, K.2    Kolman, M.3    Yu, Y.T.4    Walsh, K.5
  • 23
    • 67650520173 scopus 로고    scopus 로고
    • Protein kinase A-regulated assembly of a MEF2·HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells
    • Gordon, J. W., Pagiatakis, C., Salma, J., Du, M., Andreucci, J. J., Zhao, J., Hou, G., Perry, R. L., Dan, Q., Courtman, D. et al. (2009) Protein kinase A-regulated assembly of a MEF2·HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells. J. Biol. Chem. 284, 19027-19042
    • (2009) J. Biol. Chem. , vol.284 , pp. 19027-19042
    • Gordon, J.W.1    Pagiatakis, C.2    Salma, J.3    Du, M.4    Andreucci, J.J.5    Zhao, J.6    Hou, G.7    Perry, R.L.8    Dan, Q.9    Courtman, D.10
  • 24
    • 0033568028 scopus 로고    scopus 로고
    • HDAC4 deacetylase associates with and represses the MEF2 transcription factor
    • DOI 10.1093/emboj/18.18.5099
    • Miska, E. A., Karlsson, C., Langley, E., Nielsen, S. J., Pines, J. and Kouzarides, T. (1999) HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J. 18, 5099-5107 (Pubitemid 29443811)
    • (1999) EMBO Journal , vol.18 , Issue.18 , pp. 5099-5107
    • Miska, E.A.1    Karlsson, C.2    Langley, E.3    Nielsen, S.J.4    Pines, J.5    Kouzarides, T.6
  • 26
    • 33745812011 scopus 로고    scopus 로고
    • CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy
    • DOI 10.1172/JCI27438
    • Backs, J., Song, K., Bezprozvannaya, S., Chang, S. and Olson, E. N. (2006) CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. J. Clin. Invest. 116, 1853-1864 (Pubitemid 44033310)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1853-1864
    • Backs, J.1    Song, K.2    Bezprozvannaya, S.3    Chang, S.4    Olson, E.N.5
  • 27
    • 43249121693 scopus 로고    scopus 로고
    • Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4
    • DOI 10.1128/MCB.01611-07
    • Backs, J., Backs, T., Bezprozvannaya, S., McKinsey, T. A. and Olson, E. N. (2008) Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4. Mol. Cell. Biol. 28, 3437-3445 (Pubitemid 351657105)
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.10 , pp. 3437-3445
    • Backs, J.1    Backs, T.2    Bezprozvannaya, S.3    McKinsey, T.A.4    Olson, E.N.5
  • 28
    • 0037287068 scopus 로고    scopus 로고
    • CaM kinase IIδC phosphorylation of 14-3-3β in vascular smooth muscle cells: Activation of class II HDAC repression
    • DOI 10.1023/A:1021158216582
    • Ellis, J. J., Valencia, T. G., Zeng, H., Roberts, L. D., Deaton, R. A. and Grant, S. R. (2003) CaM kinase IIδC phosphorylation of 14-3-3β in vascular smooth muscle cells: activation of class II HDAC repression. Mol. Cell. Biochem. 242, 153-161 (Pubitemid 36240541)
    • (2003) Molecular and Cellular Biochemistry , vol.242 , Issue.1-2 , pp. 153-161
    • Ellis, J.J.1    Valencia, T.G.2    Zeng, H.3    Don, R.L.4    Deaton, R.A.5    Grant, S.R.6
  • 31
    • 36049028271 scopus 로고    scopus 로고
    • Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy
    • DOI 10.1161/ATVBAHA.107.151704, PII 0004360520071100000013
    • Xu, X., Ha, C. H., Wong, C., Wang, W., Hausser, A., Pfizenmaier, K., Olson, E. N., McKinsey, T. A. and Jin, Z. G. (2007) Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy. Arterioscler. Thromb. Vasc. Biol. 27, 2355-2362 (Pubitemid 350203950)
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.11 , pp. 2355-2362
    • Xu, X.1    Ha, C.-H.2    Wong, C.3    Wang, W.4    Hausser, A.5    Pfizenmaier, K.6    Olson, E.N.7    McKinsey, T.A.8    Jin, Z.-G.9
  • 32
    • 0030610249 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II γ-subunit variants expressed in vascular smooth muscle, brain, and cardiomyocytes
    • 2+/calmodulin-dependent protein kinase II γ-subunit variants expressed in vascular smooth muscle, brain, and cardiomyocytes. J. Biol. Chem. 272, 9393-9400
    • (1997) J. Biol. Chem. , vol.272 , pp. 9393-9400
    • Singer, H.A.1    Benscoter, H.A.2    Schworer, C.M.3
  • 35
    • 0023916169 scopus 로고
    • Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
    • Geisterfer, A. A., Peach, M. J. and Owens, G. K. (1988) Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ. Res. 62, 749-756
    • (1988) Circ. Res. , vol.62 , pp. 749-756
    • Geisterfer, A.A.1    Peach, M.J.2    Owens, G.K.3
  • 36
    • 0030610640 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II in the mitogen-activated protein kinase signaling cascade of cultured rat aortic vascular smooth muscle cells
    • 2+/calmodulin-dependent protein kinase II in the mitogen-activated protein kinase signaling cascade of cultured rat aortic vascular smooth muscle cells. Circ. Res. 81, 575-584
    • (1997) Circ. Res. , vol.81 , pp. 575-584
    • Abraham, S.T.1    Benscoter, H.A.2    Schworer, C.M.3    Singer, H.A.4
  • 39
    • 25444466164 scopus 로고    scopus 로고
    • Adhesion-dependent activation of CaMKII and regulation of ERK activation in vascular smooth muscle
    • DOI 10.1152/ajpcell.00064.2005
    • Lu, K. K., Armstrong, S. E., Ginnan, R. and Singer, H. A. (2005) Adhesion-dependent activation of CaMKII and regulation of ERK activation in vascular smooth muscle. Am. J. Physiol. Cell Physiol. 289, C1343-C1350 (Pubitemid 41456851)
    • (2005) American Journal of Physiology - Cell Physiology , vol.289 , Issue.5
    • Lu, K.K.1    Armstrong, S.E.2    Ginnan, R.3    Singer, H.A.4
  • 40
    • 0037728615 scopus 로고    scopus 로고
    • HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis
    • DOI 10.1016/S1074-7613(03)00109-2
    • Dequiedt, F., Kasler, H., Fischle, W., Kiermer, V., Weinstein, M., Herndier, B. G. and Verdin, E. (2003) HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity 18, 687-698 (Pubitemid 36588585)
    • (2003) Immunity , vol.18 , Issue.5 , pp. 687-698
    • Dequiedt, F.1    Kasler, H.2    Fischle, W.3    Kiermer, V.4    Weinstein, M.5    Herndier, B.G.6    Verdin, E.7
  • 41
    • 75149163016 scopus 로고    scopus 로고
    • CREB-dependent Nur77 induction following depolarization in PC12 cells and neurons is modulated by MEF2 transcription factors
    • Lam, B. Y., Zhang, W., Ng, D. C., Maruthappu, M., Roderick, H. L. and Chawla, S. (2010) CREB-dependent Nur77 induction following depolarization in PC12 cells and neurons is modulated by MEF2 transcription factors. J. Neurochem. 112, 1065-1073
    • (2010) J. Neurochem. , vol.112 , pp. 1065-1073
    • Lam, B.Y.1    Zhang, W.2    Ng, D.C.3    Maruthappu, M.4    Roderick, H.L.5    Chawla, S.6
  • 43
    • 77955686258 scopus 로고    scopus 로고
    • Regulatory signal transduction pathways for class IIa histone deacetylases
    • Parra, M. and Verdin, E. (2010) Regulatory signal transduction pathways for class IIa histone deacetylases. Curr. Opin. Pharmacol. 10, 454-460
    • (2010) Curr. Opin. Pharmacol. , vol.10 , pp. 454-460
    • Parra, M.1    Verdin, E.2
  • 44
    • 45749116898 scopus 로고    scopus 로고
    • Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis
    • Ha, C. H., Wang, W., Jhun, B. S., Wong, C., Hausser, A., Pfizenmaier, K., McKinsey, T. A., Olson, E. N. and Jin, Z. G. (2008) Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis. J. Biol. Chem. 283, 14590-14599
    • (2008) J. Biol. Chem. , vol.283 , pp. 14590-14599
    • Ha, C.H.1    Wang, W.2    Jhun, B.S.3    Wong, C.4    Hausser, A.5    Pfizenmaier, K.6    McKinsey, T.A.7    Olson, E.N.8    Jin, Z.G.9
  • 47
    • 33947311828 scopus 로고    scopus 로고
    • Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
    • DOI 10.1101/gad.1513107
    • Parra, M., Mahmoudi, T. and Verdin, E. (2007) Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev. 21, 638-643 (Pubitemid 46440285)
    • (2007) Genes and Development , vol.21 , Issue.6 , pp. 638-643
    • Parra, M.1    Mahmoudi, T.2    Verdin, E.3
  • 49
    • 0033623655 scopus 로고    scopus 로고
    • 2+/calmodulin- dependent protein kinase II associated with an endoplasmic reticulum stress response in vascular smooth muscle
    • 2+/calmodulin-dependent protein kinase II associated with an endoplasmic reticulum stress response in vascular smooth muscle. Mol. Cell. Biochem. 213, 83-92
    • (2000) Mol. Cell. Biochem. , vol.213 , pp. 83-92
    • Van Riper, D.A.1    Schworer, C.M.2    Singer, H.A.3
  • 50
    • 33746228132 scopus 로고    scopus 로고
    • Histone Deacetylase 7 Maintains Vascular Integrity by Repressing Matrix Metalloproteinase 10
    • DOI 10.1016/j.cell.2006.05.040, PII S0092867406008130
    • Chang, S., Young, B. D., Li, S., Qi, X., Richardson, J. A. and Olson, E. N. (2006) Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 126, 321-334 (Pubitemid 44092958)
    • (2006) Cell , vol.126 , Issue.2 , pp. 321-334
    • Chang, S.1    Young, B.D.2    Li, S.3    Qi, X.4    Richardson, J.A.5    Olson, E.N.6
  • 51
    • 70249105417 scopus 로고    scopus 로고
    • Chemokine degradation by the Group A streptococcal serine proteinase ScpC can be reconstituted in vitro and requires two separate domains
    • Fritzer, A., Noiges, B., Schweiger, D., Rek, A., Kungl, A. J., von, G. A., Nagy, E. and Meinke, A. L. (2009) Chemokine degradation by the Group A streptococcal serine proteinase ScpC can be reconstituted in vitro and requires two separate domains. Biochem. J. 422, 533-542
    • (2009) Biochem. J. , vol.422 , pp. 533-542
    • Fritzer, A.1    Noiges, B.2    Schweiger, D.3    Rek, A.4    Kungl, A.J.5    Von, G.A.6    Nagy, E.7    Meinke, A.L.8
  • 52
    • 0033681541 scopus 로고    scopus 로고
    • Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2
    • Youn, H. D. and Liu, J. O. (2000) Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2. Immunity 13, 85-94
    • (2000) Immunity , vol.13 , pp. 85-94
    • Youn, H.D.1    Liu, J.O.2
  • 54
    • 0037126018 scopus 로고    scopus 로고
    • Protective function of transcription factor TR3 orphan receptor in atherogenesis: Decreased lesion formation in carotid artery ligation model in TR3 transgenic mice
    • Arkenbout, E. K., de Waard, V., van Braqt, M., van Achterberg, T. A., Grimbergen, J. M., Pichon, B., Pannekoek, H. and de Vries, C. J. (2002) Protective function of transcription factor TR3 orphan receptor in atherogenesis: decreased lesion formation in carotid artery ligation model in TR3 transgenic mice. Circulation 106, 1530-1535
    • (2002) Circulation , vol.106 , pp. 1530-1535
    • Arkenbout, E.K.1    De Waard, V.2    Van Braqt, M.3    Van Achterberg, T.A.4    Grimbergen, J.M.5    Pichon, B.6    Pannekoek, H.7    De Vries, C.J.8
  • 55
    • 0037805720 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy
    • DOI 10.1074/jbc.M209998200
    • Davis, F. J., Gupta, M., Camoretti-Mercado, B., Schwartz, R. J. and Gupta, M. P. (2003) Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4: implications in cardiac muscle gene regulation during hypertrophy. J. Biol. Chem. 278, 20047-20058 (Pubitemid 36799198)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.22 , pp. 20047-20058
    • Davis, F.J.1    Gupta, M.2    Camoretti-Mercado, B.3    Schwartz, R.J.4    Gupta, M.P.5


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