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Volumn 109, Issue 19, 2012, Pages 7136-7137

Naturally improving insulin resistance with amorfrutins

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; AMORFRUTIN 1; ANTIDIABETIC AGENT; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR BINDING PROTEIN; GLUCOSE; HEMOGLOBIN A1C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; ROSIGLITAZONE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

EID: 84860794310     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204455109     Document Type: Note
Times cited : (11)

References (27)
  • 1
    • 79960202841 scopus 로고    scopus 로고
    • Type 2 diabetes across generations: From pathophysiology to prevention and management
    • Nolan CJ, Damm P, Prentki M (2011) Type 2 diabetes across generations: From pathophysiology to prevention and management. Lancet 378:169-181.
    • (2011) Lancet , vol.378 , pp. 169-181
    • Nolan, C.J.1    Damm, P.2    Prentki, M.3
  • 2
    • 79960995107 scopus 로고    scopus 로고
    • Macrovascular effects and safety issues of therapies for type 2 diabetes
    • Plutzky J (2011) Macrovascular effects and safety issues of therapies for type 2 diabetes. Am J Cardiol 108(3, suppl)25B-32B.
    • (2011) Am J Cardiol , vol.108 , Issue.3 SUPPL.
    • Plutzky, J.1
  • 3
    • 70349329717 scopus 로고    scopus 로고
    • Antidiabetic agents and cardiovascular risk in type 2 diabetes
    • Zarich SW (2009) Antidiabetic agents and cardiovascular risk in type 2 diabetes. Nat Rev Endocrinol 5: 500-506.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 500-506
    • Zarich, S.W.1
  • 4
    • 79959807374 scopus 로고    scopus 로고
    • Type 2 diabetes can be prevented with early pharmacological intervention
    • DeFronzo RA, Abdul-Ghani M (2011) Type 2 diabetes can be prevented with early pharmacological intervention. Diabetes Care 34(suppl 2):S202-S209.
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 2
    • DeFronzo, R.A.1    Abdul-Ghani, M.2
  • 5
    • 84860795758 scopus 로고    scopus 로고
    • Amorfrutins are potent anti-diabetic dietary natural products
    • Weidner C, et al. (2012) Amorfrutins are potent anti-diabetic dietary natural products. Proc Natl Acad Sci USA 109:7257-7262.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 7257-7262
    • Weidner, C.1
  • 6
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator- Activated receptor gamma (PPAR gamma)
    • Lehmann JM, et al. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator- activated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1
  • 7
    • 77955657267 scopus 로고    scopus 로고
    • Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: The missing links. The Claude Bernard Lecture 2009
    • DeFronzo RA (2010) Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: The missing links. The Claude Bernard Lecture 2009. Diabetologia 53: 1270-1287.
    • (2010) Diabetologia , vol.53 , pp. 1270-1287
    • DeFronzo, R.A.1
  • 8
    • 76049086229 scopus 로고    scopus 로고
    • PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization
    • Sugii S, et al. (2009) PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proc Natl Acad Sci USA 106:22504-22509.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 22504-22509
    • Sugii, S.1
  • 9
    • 34547431645 scopus 로고    scopus 로고
    • Adipose tissue expandability in the maintenance of metabolic homeostasis
    • Gray SL, Vidal-Puig AJ (2007) Adipose tissue expandability in the maintenance of metabolic homeostasis. Nutr Rev 65:S7-S12.
    • (2007) Nutr Rev , vol.65
    • Gray, S.L.1    Vidal-Puig, A.J.2
  • 11
    • 79955694276 scopus 로고    scopus 로고
    • Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones
    • Lu M, et al. (2011) Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med 17:618-622.
    • (2011) Nat Med , vol.17 , pp. 618-622
    • Lu, M.1
  • 12
    • 77955285732 scopus 로고    scopus 로고
    • Rosiglitazone revisited: An updated meta-analysis of risk for myocardial infarction and cardiovascular mortality
    • Nissen SE, Wolski K (2010) Rosiglitazone revisited: An updated meta-analysis of risk for myocardial infarction and cardiovascular mortality. Arch Intern Med 170: 1191-1201.
    • (2010) Arch Intern Med , vol.170 , pp. 1191-1201
    • Nissen, S.E.1    Wolski, K.2
  • 13
    • 63849148589 scopus 로고    scopus 로고
    • Safety and tolerability of pioglitazone in high-risk patients with type 2 diabetes: An overview of data from PROactive
    • PROactive Investigators
    • Dormandy J, Bhattacharya M, van Troostenburg de Bruyn AR; PROactive Investigators (2009) Safety and tolerability of pioglitazone in high-risk patients with type 2 diabetes: An overview of data from PROactive. Drug Saf 32:187-202.
    • (2009) Drug Saf , vol.32 , pp. 187-202
    • Dormandy, J.1    Bhattacharya, M.2    Van Troostenburg De Bruyn, A.R.3
  • 14
    • 79951716557 scopus 로고    scopus 로고
    • Type 2 diabetes: Uses of thiazolidinediones and insulin
    • Bloomgarden ZT (2011) Type 2 diabetes: Uses of thiazolidinediones and insulin. Diabetes Care 34:e11-e16.
    • (2011) Diabetes Care , vol.34
    • Bloomgarden, Z.T.1
  • 15
    • 77952492038 scopus 로고    scopus 로고
    • Discovery and development of selective PPAR gamma modulators as safe and effective antidiabetic agents
    • Doshi LS, Brahma MK, Bahirat UA, Dixit AV, Nemmani KV (2010) Discovery and development of selective PPAR gamma modulators as safe and effective antidiabetic agents. Expert Opin Investig Drugs 19: 489-512.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 489-512
    • Doshi, L.S.1    Brahma, M.K.2    Bahirat, U.A.3    Dixit, A.V.4    Nemmani, K.V.5
  • 19
    • 77951865861 scopus 로고    scopus 로고
    • Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans
    • Lefebvre B, et al. (2010) Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans. J Clin Invest 120:1454-1468.
    • (2010) J Clin Invest , vol.120 , pp. 1454-1468
    • Lefebvre, B.1
  • 20
    • 80053131732 scopus 로고    scopus 로고
    • Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
    • Choi JH, et al. (2011) Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. Nature 477:477-481.
    • (2011) Nature , vol.477 , pp. 477-481
    • Choi, J.H.1
  • 21
    • 84863012459 scopus 로고    scopus 로고
    • Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones
    • Dutchak PA, et al. (2012) Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones. Cell 148:556-567.
    • (2012) Cell , vol.148 , pp. 556-567
    • Dutchak, P.A.1
  • 22
    • 84859157277 scopus 로고    scopus 로고
    • Roles of PPARs in NAFLD: Potential therapeutic targets
    • Tailleux A, Wouters K, Staels B (2011) Roles of PPARs in NAFLD: Potential therapeutic targets. Biochim Biophys Acta 1821:809-818.
    • (2011) Biochim Biophys Acta , vol.1821 , pp. 809-818
    • Tailleux, A.1    Wouters, K.2    Staels, B.3
  • 23
    • 81055144760 scopus 로고    scopus 로고
    • Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity
    • Li P, et al. (2011) Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity. Cell 147:815-826.
    • (2011) Cell , vol.147 , pp. 815-826
    • Li, P.1
  • 24
    • 25144441178 scopus 로고    scopus 로고
    • Fluid retention mediated by renal PPAR-gamma
    • Staels B (2005) Fluid retention mediated by renal PPAR-gamma. Cell Metab 2:77-78.
    • (2005) Cell Metab , vol.2 , pp. 77-78
    • Staels, B.1
  • 25
    • 56049115334 scopus 로고    scopus 로고
    • Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression
    • Dat NT, et al. (2008) Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod 71:1696-1700.
    • (2008) J Nat Prod , vol.71 , pp. 1696-1700
    • Dat, N.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.