Hsp27 silencing coordinately inhibits proliferation and promotes Fas-induced apoptosis by regulating the PEA-15 molecular switch

Cell Death and Differentiation

Volumn 19, Issue 6, 2012, Pages 990-1002

  Hayashi, N ^a   Peacock, J W ^a   Beraldi, E ^a   Zoubeidi, A ^a   Gleave, M E ^a   Ong, C J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Akt; Hsp27; PEA 15 PED; Prostate cancer

Indexed keywords

FAS ASSOCIATED DEATH DOMAIN PROTEIN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN PEA 15; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTROCYTE; CANCER CELL; CANCER INHIBITION; CELL LINE; CELL PROLIFERATION; CELL STRAIN LNCAP; CHROMOSOME 10; GROWTH INHIBITION; HUMAN; HUMAN CELL; NULL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; WILD TYPE;

ANTIGENS, CD95; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HSP27 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84860757279     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.184     Document Type: Article

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